Zalophus californianus (California sea lion): 113912439
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Entry
113912439 CDS
T07874
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04022
cGMP-PKG signaling pathway
zca04024
cAMP signaling pathway
zca04062
Chemokine signaling pathway
zca04071
Sphingolipid signaling pathway
zca04270
Vascular smooth muscle contraction
zca04350
TGF-beta signaling pathway
zca04360
Axon guidance
zca04510
Focal adhesion
zca04520
Adherens junction
zca04530
Tight junction
zca04611
Platelet activation
zca04670
Leukocyte transendothelial migration
zca04810
Regulation of actin cytoskeleton
zca04921
Oxytocin signaling pathway
zca05135
Yersinia infection
zca05163
Human cytomegalovirus infection
zca05200
Pathways in cancer
zca05205
Proteoglycans in cancer
zca05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
113912439 (ROCK1)
04071 Sphingolipid signaling pathway
113912439 (ROCK1)
04024 cAMP signaling pathway
113912439 (ROCK1)
04022 cGMP-PKG signaling pathway
113912439 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
113912439 (ROCK1)
04520 Adherens junction
113912439 (ROCK1)
04530 Tight junction
113912439 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113912439 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
113912439 (ROCK1)
04670 Leukocyte transendothelial migration
113912439 (ROCK1)
04062 Chemokine signaling pathway
113912439 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
113912439 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
113912439 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
113912439 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113912439 (ROCK1)
05206 MicroRNAs in cancer
113912439 (ROCK1)
05205 Proteoglycans in cancer
113912439 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
113912439 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
113912439 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113912439 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
zca03036
]
113912439 (ROCK1)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
113912439 (ROCK1)
Protein kinases [BR:
zca01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
113912439 (ROCK1)
Chromosome and associated proteins [BR:
zca03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
113912439 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
113912439
NCBI-ProteinID:
XP_027431278
UniProt:
A0A6J2BN87
LinkDB
All DBs
Position
14:complement(43883585..44036605)
Genome browser
AA seq
1355 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRILENSKTQTD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKHMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNREYLKKIQELQSEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDIELLRKENE
ELTDKTRRAEEEYKLKKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKRWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTSS
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
ccgaaatcggaagtgaattcagattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccactaggaag
gtatatgctatgaagcttctcagtaaatttgaaatgattaagagatccgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaacagcccttgggtcgtccagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctataccgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcatagagatgtgaaa
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattac
atttcccctgaagtattaaaatctcaaggtggtgatggctattatggacgcgaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttacttttcct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcagtgggcttgggaaacactcagagacactgtagcacctgttgtacctgatttaagc
agtgacatcgatacaagtaattttgatgacttggaggaagataaaggagatgaagaaaca
ttccccatacctaaagcttttgttggcaatcagttaccttttgtaggatttacatattat
agcaatcgtagatacttatcttcggcaaatcctaatgataaccgaagtagccccaatgtg
gataagagcttgcaggaaaatttgcaaaaaacaatttataagctggaagaacagctgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaacctagaatctaca
gtgtctcagattgagaaggaaaaaatgttgctccagcatagaattaatgagtaccagaga
aaagcagaacaggaaaatgagaagaggaggaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtaagtcaaaattcacagcttgctaatgagaagctg
gcacaattacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gccgtaagattaaggaagagtcacacagagatgagtaagtcagttagtcagctagagtcc
ctaaacagagaattgcaggagagaaatagaattttagagaattccaagacacagacggac
aaggactattaccagctgcaagctgtgttagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaggaggtgaagcat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaagctcaagacatgcttaat
cactcagaaaaggaaaaaaataatttagagatagatttaaactataagcttaaatcatta
caacaacgtttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaaaaagctg
aaggaagagagagaagctagagagaaggctgaaaatagagttgttcagattgagaaacag
tgttcaatgctagatgttgatctgaaacaatctcagcagaagctcgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatcccttcaactggagcaggaatca
aacaagcgactgttgttacagaatgaattgaagactcaagcatttgaagcagacaattta
aaaggtctagaaaagcacatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgaattagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctccaagatcagcttgaagctgagcagtatttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaatacttaaagaaaatacaagag
ctacaaagtgagaaggaaactcttgctactcagttggatctagcagaaacaaaagctgag
tctgagcagttggctcgagggctgctggaagaacagtattttgaattaacccaagaaagc
aagaaagctgcttccagaaatagacaagagattacagataaagatcatactgttagtcgg
cttgaagaaacaaacagcatgttaaccaaagatattgaattattaagaaaagaaaatgaa
gagctaactgataaaacgaggagggcagaggaagaatataaattgaagaaggaggaggag
atcagtaatcttaaggctgcctttgaaaagaatatcaatacagaaagaacccttaaaacg
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaagaaaaggaaaatcgaaagctgcaactggaa
ctcaaccaagaaagagagaaattcaatcagatggtagtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgaacttcagatgcaattg
gctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggtaaccttccagagtcaaga
attgaaggttggctttcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctataatgatgaacaagataaggaa
caatccaatccatccatggtattggacatagataaattgtttcacgttcgacctgtaacc
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacaacaagcggaaaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcctgcc
aactgtgaggcatgtgccaaacctctctggcatgtttttaagccacctcctgccctggaa
tgtcgaagatgccacgtgaagtgccacagagatcacctggataagaaagaggacttaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcgtgt
tctcaggatgaacaaaaaagatgggtaacacatttggtaaagaagatccctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacgctttctacaagatctactgcaaatcag
tctttccgaaaagtggtcaaaaatacatctggaaaaactagcagttaa
DBGET
integrated database retrieval system