Zalophus californianus (California sea lion): 113912650
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Entry
113912650 CDS
T07874
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04020
Calcium signaling pathway
zca04022
cGMP-PKG signaling pathway
zca04024
cAMP signaling pathway
zca04148
Efferocytosis
zca04260
Cardiac muscle contraction
zca04261
Adrenergic signaling in cardiomyocytes
zca04380
Osteoclast differentiation
zca04919
Thyroid hormone signaling pathway
zca04972
Pancreatic secretion
zca05010
Alzheimer disease
zca05017
Spinocerebellar ataxia
zca05022
Pathways of neurodegeneration - multiple diseases
zca05410
Hypertrophic cardiomyopathy
zca05412
Arrhythmogenic right ventricular cardiomyopathy
zca05414
Dilated cardiomyopathy
zca05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
113912650 (ATP2A2)
04024 cAMP signaling pathway
113912650 (ATP2A2)
04022 cGMP-PKG signaling pathway
113912650 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
113912650 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
113912650 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
113912650 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
113912650 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
113912650 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
113912650 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
113912650 (ATP2A2)
05017 Spinocerebellar ataxia
113912650 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
113912650 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
113912650 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
113912650 (ATP2A2)
05414 Dilated cardiomyopathy
113912650 (ATP2A2)
05415 Diabetic cardiomyopathy
113912650 (ATP2A2)
Enzymes [BR:
zca01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
113912650 (ATP2A2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
113912650
NCBI-ProteinID:
XP_027431976
UniProt:
A0A6J2BLV9
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All DBs
Position
14:8323155..8380028
Genome browser
AA seq
997 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDSCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKVERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTPGV
KQKVMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKDDNPDFEGVDCAIFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPAILE
NT seq
2994 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagagatggggttccaacgag
ttaccggctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcttgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgagaatgcaatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtatatcgacaggacagaaagagtgtccagcggatt
aaagctaaagacatcgttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctaagagttgaccagtccattctc
acaggtgagtctgtatctgtcatcaagcacactgaccctgtcccggacccacgggctgtc
aatcaagataaaaagaacatgctcttttctggtacaaacattgctgctggcaaagccatg
ggagtggtggtggcaactggagtgaacacggaaattggcaagatccgggatgaaatggtg
gcaacagagcaggagagaacccccctccagcagaaactagatgagtttggggaacagctt
tccaaagtcatctccctgatttgcattgcagtctggatcataaacattgggcacttcaac
gacccagttcatggaggctcctggatcaggggcgctatttactactttaaaattgcggtg
gctctggctgtggcagccattcctgaaggtctgcctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgctattgttcgaagcctcccttctgtggaa
acccttggttgtacttctgttatctgctcagacaagactggtacactgacaacgaaccag
atgtctgtgtgcaggatgttcattctggacaaagttgaaggtgatagttgttcccttaat
gagtttaccattactggatcaacatacgcccctattggagaagtgcataaagatgataaa
ccagtgaaatgtcatcaatatgatggtcttgtggaattggcaacaatttgtgctctttgt
aatgattctgcgttggattacaatgaggcgaagggtgtgtatgaaaaagttggagaagct
acggagactgctcttacttgcctagtagagaagatgaatgtattcgatactgaattgaag
ggtctttctaaagtagagcgagcaaatgcctgcaactcggtcattaagcaattgatgaag
aaggaatttactctggagttttcacgtgatagaaaatcgatgtcagtttattgtacacca
aacaaaccaagccggacatcgatgagcaaaatgtttgtgaagggtgctcctgaaggtgtc
attgacaggtgcacccacattcgagttggaagtactaaagttcctatgaccccgggagtc
aaacagaaggtcatgtctgtcattcgggaatggggtagtggcagcgacacactgcggtgc
ctggctctggccactcatgacaacccactaagaagagaagaaatgaaccttgaggactct
gccaactttattaaatatgagaccaatctgactttcgttggctgcgtgggcatgctggac
cctccgagaattgaagtggcctcctctgtgaagctgtgccggcaggcaggcatccgggtt
atcatgatcactggggacaacaagggcactgctgtggccatctgtcggcgcattggcatc
ttcgggcaggacgaggatgtgacgtcgaaagcttttacgggtcgggagtttgatgagctc
agtccttcagcccagagagatgcctgtttgaacgcccgatgtttcgctcgagttgaacct
tcccacaagtcaaaaattgtagaatttcttcagtcttttgatgagataacagctatgact
ggggatggcgtgaatgatgctcctgccctgaagaaatctgagatcggcattgccatgggc
tctggcacggcagtggctaaaacggcgtctgagatggttctggccgacgacaacttctcc
accatcgtggctgcagtggaggaggggcgggccatctacaacaatatgaagcagtttatc
cgctacctcatctcgtcgaatgtgggggaagttgtctgtatcttcctgacagcagccctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcccgccactgccctggggttcaaccctcccgatctggacatcatgaataaaccaccc
cggaacccgaaggaacccctgatcagcggatggctctttttccgttatctggccattggc
tgttacgttggcgctgctaccgtgggtgctgctgcgtggtggttcattgctgccgacgga
gggccaagagtgtccttctaccagctgagccacttcctacagtgtaaagatgacaacccg
gactttgaaggagtggattgtgcaatctttgagtccccatacccgatgacaatggcgctt
tctgttctagtaaccatagagatgtgtaacgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgcccccttgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgcttcacttcctcatcctctacgtggaacctttgccacttattttccagatcacaccg
ctgaatttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggac
gagacactcaagtttgtggcccgcaactacctggaacctgcaatactggagtaa
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