KEGG   Zalophus californianus (California sea lion): 113914876
Entry
113914876         CDS       T07874                                 
Symbol
HRAS
Name
(RefSeq) GTPase HRas isoform X1
  KO
K02833  GTPase HRas
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca01521  EGFR tyrosine kinase inhibitor resistance
zca01522  Endocrine resistance
zca04010  MAPK signaling pathway
zca04012  ErbB signaling pathway
zca04014  Ras signaling pathway
zca04015  Rap1 signaling pathway
zca04062  Chemokine signaling pathway
zca04068  FoxO signaling pathway
zca04071  Sphingolipid signaling pathway
zca04072  Phospholipase D signaling pathway
zca04137  Mitophagy - animal
zca04140  Autophagy - animal
zca04144  Endocytosis
zca04150  mTOR signaling pathway
zca04151  PI3K-Akt signaling pathway
zca04210  Apoptosis
zca04211  Longevity regulating pathway
zca04213  Longevity regulating pathway - multiple species
zca04218  Cellular senescence
zca04360  Axon guidance
zca04370  VEGF signaling pathway
zca04371  Apelin signaling pathway
zca04510  Focal adhesion
zca04540  Gap junction
zca04550  Signaling pathways regulating pluripotency of stem cells
zca04625  C-type lectin receptor signaling pathway
zca04630  JAK-STAT signaling pathway
zca04650  Natural killer cell mediated cytotoxicity
zca04660  T cell receptor signaling pathway
zca04662  B cell receptor signaling pathway
zca04664  Fc epsilon RI signaling pathway
zca04714  Thermogenesis
zca04720  Long-term potentiation
zca04722  Neurotrophin signaling pathway
zca04725  Cholinergic synapse
zca04726  Serotonergic synapse
zca04730  Long-term depression
zca04810  Regulation of actin cytoskeleton
zca04910  Insulin signaling pathway
zca04912  GnRH signaling pathway
zca04915  Estrogen signaling pathway
zca04916  Melanogenesis
zca04917  Prolactin signaling pathway
zca04919  Thyroid hormone signaling pathway
zca04921  Oxytocin signaling pathway
zca04926  Relaxin signaling pathway
zca04929  GnRH secretion
zca04933  AGE-RAGE signaling pathway in diabetic complications
zca04935  Growth hormone synthesis, secretion and action
zca05010  Alzheimer disease
zca05022  Pathways of neurodegeneration - multiple diseases
zca05034  Alcoholism
zca05132  Salmonella infection
zca05160  Hepatitis C
zca05161  Hepatitis B
zca05163  Human cytomegalovirus infection
zca05165  Human papillomavirus infection
zca05166  Human T-cell leukemia virus 1 infection
zca05167  Kaposi sarcoma-associated herpesvirus infection
zca05170  Human immunodeficiency virus 1 infection
zca05200  Pathways in cancer
zca05203  Viral carcinogenesis
zca05205  Proteoglycans in cancer
zca05206  MicroRNAs in cancer
zca05207  Chemical carcinogenesis - receptor activation
zca05208  Chemical carcinogenesis - reactive oxygen species
zca05210  Colorectal cancer
zca05211  Renal cell carcinoma
zca05213  Endometrial cancer
zca05214  Glioma
zca05215  Prostate cancer
zca05216  Thyroid cancer
zca05218  Melanoma
zca05219  Bladder cancer
zca05220  Chronic myeloid leukemia
zca05221  Acute myeloid leukemia
zca05223  Non-small cell lung cancer
zca05224  Breast cancer
zca05225  Hepatocellular carcinoma
zca05226  Gastric cancer
zca05230  Central carbon metabolism in cancer
zca05231  Choline metabolism in cancer
zca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
zca05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:zca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113914876 (HRAS)
   04012 ErbB signaling pathway
    113914876 (HRAS)
   04014 Ras signaling pathway
    113914876 (HRAS)
   04015 Rap1 signaling pathway
    113914876 (HRAS)
   04370 VEGF signaling pathway
    113914876 (HRAS)
   04371 Apelin signaling pathway
    113914876 (HRAS)
   04630 JAK-STAT signaling pathway
    113914876 (HRAS)
   04068 FoxO signaling pathway
    113914876 (HRAS)
   04072 Phospholipase D signaling pathway
    113914876 (HRAS)
   04071 Sphingolipid signaling pathway
    113914876 (HRAS)
   04151 PI3K-Akt signaling pathway
    113914876 (HRAS)
   04150 mTOR signaling pathway
    113914876 (HRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    113914876 (HRAS)
   04140 Autophagy - animal
    113914876 (HRAS)
   04137 Mitophagy - animal
    113914876 (HRAS)
  09143 Cell growth and death
   04210 Apoptosis
    113914876 (HRAS)
   04218 Cellular senescence
    113914876 (HRAS)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    113914876 (HRAS)
   04540 Gap junction
    113914876 (HRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    113914876 (HRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    113914876 (HRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    113914876 (HRAS)
   04650 Natural killer cell mediated cytotoxicity
    113914876 (HRAS)
   04660 T cell receptor signaling pathway
    113914876 (HRAS)
   04662 B cell receptor signaling pathway
    113914876 (HRAS)
   04664 Fc epsilon RI signaling pathway
    113914876 (HRAS)
   04062 Chemokine signaling pathway
    113914876 (HRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    113914876 (HRAS)
   04929 GnRH secretion
    113914876 (HRAS)
   04912 GnRH signaling pathway
    113914876 (HRAS)
   04915 Estrogen signaling pathway
    113914876 (HRAS)
   04917 Prolactin signaling pathway
    113914876 (HRAS)
   04921 Oxytocin signaling pathway
    113914876 (HRAS)
   04926 Relaxin signaling pathway
    113914876 (HRAS)
   04935 Growth hormone synthesis, secretion and action
    113914876 (HRAS)
   04919 Thyroid hormone signaling pathway
    113914876 (HRAS)
   04916 Melanogenesis
    113914876 (HRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    113914876 (HRAS)
   04726 Serotonergic synapse
    113914876 (HRAS)
   04720 Long-term potentiation
    113914876 (HRAS)
   04730 Long-term depression
    113914876 (HRAS)
   04722 Neurotrophin signaling pathway
    113914876 (HRAS)
  09158 Development and regeneration
   04360 Axon guidance
    113914876 (HRAS)
  09149 Aging
   04211 Longevity regulating pathway
    113914876 (HRAS)
   04213 Longevity regulating pathway - multiple species
    113914876 (HRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    113914876 (HRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113914876 (HRAS)
   05206 MicroRNAs in cancer
    113914876 (HRAS)
   05205 Proteoglycans in cancer
    113914876 (HRAS)
   05207 Chemical carcinogenesis - receptor activation
    113914876 (HRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    113914876 (HRAS)
   05203 Viral carcinogenesis
    113914876 (HRAS)
   05230 Central carbon metabolism in cancer
    113914876 (HRAS)
   05231 Choline metabolism in cancer
    113914876 (HRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    113914876 (HRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    113914876 (HRAS)
   05225 Hepatocellular carcinoma
    113914876 (HRAS)
   05226 Gastric cancer
    113914876 (HRAS)
   05214 Glioma
    113914876 (HRAS)
   05216 Thyroid cancer
    113914876 (HRAS)
   05221 Acute myeloid leukemia
    113914876 (HRAS)
   05220 Chronic myeloid leukemia
    113914876 (HRAS)
   05218 Melanoma
    113914876 (HRAS)
   05211 Renal cell carcinoma
    113914876 (HRAS)
   05219 Bladder cancer
    113914876 (HRAS)
   05215 Prostate cancer
    113914876 (HRAS)
   05213 Endometrial cancer
    113914876 (HRAS)
   05224 Breast cancer
    113914876 (HRAS)
   05223 Non-small cell lung cancer
    113914876 (HRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    113914876 (HRAS)
   05170 Human immunodeficiency virus 1 infection
    113914876 (HRAS)
   05161 Hepatitis B
    113914876 (HRAS)
   05160 Hepatitis C
    113914876 (HRAS)
   05163 Human cytomegalovirus infection
    113914876 (HRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    113914876 (HRAS)
   05165 Human papillomavirus infection
    113914876 (HRAS)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    113914876 (HRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    113914876 (HRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    113914876 (HRAS)
  09165 Substance dependence
   05034 Alcoholism
    113914876 (HRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113914876 (HRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    113914876 (HRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    113914876 (HRAS)
   01522 Endocrine resistance
    113914876 (HRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:zca04131]
    113914876 (HRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:zca04147]
    113914876 (HRAS)
   04031 GTP-binding proteins [BR:zca04031]
    113914876 (HRAS)
Membrane trafficking [BR:zca04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    113914876 (HRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    113914876 (HRAS)
Exosome [BR:zca04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   113914876 (HRAS)
  Exosomal proteins of colorectal cancer cells
   113914876 (HRAS)
GTP-binding proteins [BR:zca04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    113914876 (HRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 Septin Ldh_1_N
Other DBs
NCBI-GeneID: 113914876
NCBI-ProteinID: XP_027436278
UniProt: A0A6J2C2P6
LinkDB
Position
11:113263009..113266250
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKVRKLSPPDEGGPG
CMSCKCLLS
NT seq 570 nt   +upstreamnt  +downstreamnt
atgacagaatataagcttgtggtggtgggtgctggaggtgtggggaagagtgccctgacc
atccagctcatccagaaccacttcgtggatgagtatgaccccaccatcgaggactcctat
cggaagcaagtggttatcgatggcgagacgtgcctgctggacattttggacacggcgggc
caggaagaatatagcgccatgcgggaccagtacatgcgcaccggagaaggcttcctgtgt
gtgtttgccatcaacaacaccaagtccttcgaggacatccaccagtaccgggagcagatc
aagcgagtgaaggactccgatgacgtgcccatggtgctggtggggaacaagtgtgacctg
gctgcccgcaccgtggagtcccggcaggcgcaggacctcgcccgcagctatggcatcccc
tacatcgagacgtcggccaagacacgccagggcgtggaggatgccttctacacgctggtg
cgagagatccggcagcacaaggtgcgaaagctgagcccgcctgacgagggtggccccggc
tgcatgagctgcaagtgcctgctctcctga

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