Zalophus californianus (California sea lion): 113916105
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Entry
113916105 CDS
T07874
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04217
Necroptosis
zca04380
Osteoclast differentiation
zca04620
Toll-like receptor signaling pathway
zca04621
NOD-like receptor signaling pathway
zca04630
JAK-STAT signaling pathway
zca04658
Th1 and Th2 cell differentiation
zca04659
Th17 cell differentiation
zca05145
Toxoplasmosis
zca05160
Hepatitis C
zca05161
Hepatitis B
zca05162
Measles
zca05164
Influenza A
zca05165
Human papillomavirus infection
zca05167
Kaposi sarcoma-associated herpesvirus infection
zca05168
Herpes simplex virus 1 infection
zca05169
Epstein-Barr virus infection
zca05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
113916105 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
113916105 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
113916105 (TYK2)
04621 NOD-like receptor signaling pathway
113916105 (TYK2)
04658 Th1 and Th2 cell differentiation
113916105 (TYK2)
04659 Th17 cell differentiation
113916105 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
113916105 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
113916105 (TYK2)
05160 Hepatitis C
113916105 (TYK2)
05171 Coronavirus disease - COVID-19
113916105 (TYK2)
05164 Influenza A
113916105 (TYK2)
05162 Measles
113916105 (TYK2)
05168 Herpes simplex virus 1 infection
113916105 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
113916105 (TYK2)
05169 Epstein-Barr virus infection
113916105 (TYK2)
05165 Human papillomavirus infection
113916105 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
113916105 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113916105 (TYK2)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
113916105 (TYK2)
Protein kinases [BR:
zca01001
]
Non-receptor tyrosine kinases
JAK family [OT]
113916105 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
Kdo
Kinase-like
FERM_C_FAK1
RIO1
ABC1
Motif
Other DBs
NCBI-GeneID:
113916105
NCBI-ProteinID:
XP_035582010
EnsemblRapid:
ENSZCAG00025000614
UniProt:
A0A6P9F4B3
LinkDB
All DBs
Position
1:complement(7647874..7667584)
Genome browser
AA seq
1195 aa
AA seq
DB search
MASLFLAKPAVKSMPLCHWGATTRDSRPDGDGAQPMATRGGLKVLLHWAGPGGGDPWVTF
SEATLTAEEVCIHIAQKVGITPSCLNLFALFDAQAQVWLPPNHVLEISGDMSLTLYFRMR
FYFRNWHGTNPQEPAVYRCGPPGPKSSSEQAEQGMQLLDPASFEYLFEQGKHEFVNDVAS
LSELSSEEEIHHFKNESLGMAFLHLCHLALYHGIPLGKVAKKISFKDCIPRSFRLQIRQH
NALTRLRLRNIFRRFVRAFQPGHVSQQVIMVKYLATLELLAPRFGTERLPVCHLELPAQA
VGEPYYIRDGGQAPSEPGPELATGPPTHEVLVTGTGGIQWRPIHAEGPRGDGSSRNPRAG
PFGKKTKVPEVGNQPEDRPQEAPWAYFCDFKDITHVVLKERHVSIRCQDNKSLELTLPSR
AMALSLVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIQDGIHGPLLEPFVLAKLRPEDGL
YLIHWSTSHLNRLILTVAQREQAPGTQHLHLRKFPIELQAGGFMLEGWDRSFPSVRELRA
ALQGCSLRAGDDCFSLRRCCLPRPGEISNLIIMRGHRASTGPPNLSQLSFHRICQDDITQ
LSHLGQGTRTNVYEGILRVGGRGPKEGTANDEDPPTPGGDCGQELRVVLKVLDPSHHDIA
LAFYETASLMSQVSHVHLAFVHGICVHGSENIMVTEYVEHGPLDVWLRREKGHVPVAWKV
AVAQQLASALSYLEDKSLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALSREER
VERIPWTAPECLSGGANSLTTAADKWGFGATLLEICFDGEAPLQGRGPSEKECFYQKQHR
LPQPSCPELATLTSQCLTYEPAQRPSFRTILRDLTQLQPQNLADLLAVNPDSPASDPTIF
HKRYLKKIRDLGEGHFGKVSLSCYDPTNDGTGEMVAVKALKADCGPQLRSGWRREIDILR
TLYHKHIVKYKGCCEDPGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMA
YLHAQHYVHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPEC
LKECKFYYASDVWSFGVTMYELLTYCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGE
RLPRPERCPCEIYLLMKNCWEAEASFRPTFQNLIPILKTVQEKYQGQAASVFSVC
NT seq
3588 nt
NT seq
+upstream
nt +downstream
nt
atggcctctctctttctagccaagccagctgtcaaaagcatgcctctgtgccattggggt
gccaccaccagggacagcaggcctgatggcgatggagctcagcccatggccaccagggga
ggcctgaaggtccttctgcactgggctggccctggcggcggggacccctgggtcaccttc
agcgaggccacactgaccgcagaggaggtctgcatccacattgcacaaaaagtcggcatc
actccgtcctgcctcaatctctttgctctcttcgatgcccaggctcaggtctggctgccc
ccaaaccacgtcttggagatctccggagacatgagcctgacattgtacttccgcatgagg
ttttatttccggaactggcatggcacgaatcctcaggagccggctgtataccgctgtggg
cccccagggcccaagtcttcctcagaacaggcagagcaggggatgcaactgctggaccca
gcctcctttgagtacctctttgagcagggcaagcatgagtttgtgaatgacgtggcatcg
ctgtcagagctgtcgagcgaggaggagatccaccattttaagaacgagagtctgggcatg
gccttcctgcatctctgccaccttgctctctaccacggcatccccctggggaaggtggcc
aagaagatcagcttcaaggactgcatcccacgctccttccggctgcagatccggcagcac
aacgcgctcacgcggctgcgcctgcggaacatcttccgcaggttcgtgcgggccttccag
ccaggccacgtgtcacagcaggtcatcatggtcaaatacctggccacgctcgagctgctg
gcaccccgctttggcactgagcgcctgcccgtgtgccacctggagctgccggcccaggcc
gtcggggagccctactacatccgggacggcgggcaggctccctcagagcctgggccggag
ttggccaccgggccccccactcatgaggtgctggtgacgggcacgggtggcatccagtgg
cggccgatacacgcagagggtcccagaggtgatggcagcagcaggaatccccgtgctggc
ccatttgggaagaaaaccaaggtcccagaggtgggcaaccagcccgaggacaggcctcag
gaagcgccctgggcctacttctgtgacttcaaggatatcacgcacgtggtgctgaaggaa
cgccacgtcagcatccgctgtcaggacaacaagagcctggagctgaccctgccttcccgg
gccatggccctgtccttggtgtcgctggtggacggctatttccgcctgaccgctgactcg
agccactacctgtgccacgaggtggctccgccacggctagtgatgagcatccaggacggt
atccacggacccctgctggagccatttgtgctggccaagctgcggcctgaggatggcctc
tacctcatccattggagcaccagccacctcaaccgcctcatcctcacggtggcccagcgt
gagcaggccccgggcacacagcacctgcacctgcgtaaattccccattgagctgcaggcc
gggggcttcatgctggagggctgggaccggtccttccccagcgtgcgggagctgcgggct
gccctccagggttgctccctgcgggctggtgatgactgtttctccctgcgccgctgctgc
ctgcctcggccgggagagatctccaacctcatcatcatgcgggggcatcgggccagcact
ggtccgcccaacctcagccagctcagcttccaccggatctgccaggatgacatcacccag
ctgtcccacttgggccaaggcacgaggaccaatgtgtatgagggcatcttacgagtgggg
ggcagaggccccaaggagggcactgccaatgatgaggacccccccacgcccggtggggac
tgtgggcaagagctccgagtggtactcaaggtgctggaccccagtcaccacgacatcgcc
ctggccttctacgagacagccagcctcatgagccaggtttcccacgtgcacctggccttt
gtacacggcatctgcgtgcacggctctgagaacatcatggtaacagagtacgtggagcac
gggcccctggacgtgtggctgcggcgggagaagggccacgtgcctgtggcctggaaggtg
gccgtggcccagcagctggccagcgccctcagctatctggaagacaagagcctggttcat
ggtaatgtgtgtggccggaacatcctgctggcgaggctgggactggcagagggcactagc
cccttcatcaagctgagcgaccctggtgtgggcctgggtgccctttctagagaggagcgg
gtggagcggatcccctggacagcccccgagtgcctatctggaggagccaacagcctaacc
actgcagctgataaatggggctttggtgccaccctcctggagatctgctttgacggggag
gcccctctgcagggccgtggcccttctgagaaagagtgcttctaccagaagcagcaccgg
cttcctcagccctcctgcccggagctggccacactcaccagccagtgcctgacctatgaa
ccagctcagcggccctccttccgcaccatcctgcgtgacctcactcagctgcagccccaa
aatcttgctgacctcttggctgtgaatcccgactcgcctgcgtcagaccccaccattttc
cacaagcgctatttgaaaaagatccgggatctgggcgagggtcatttcggcaaggtcagc
ctgtcctgctacgaccccacgaacgacggcaccggtgagatggtggccgtgaaggccctc
aaggcggactgcggcccccagctccgcagcggctggaggcgggagatcgacatcctgcgc
acgctctaccacaagcacatcgtcaagtacaagggctgctgcgaggacccaggcgagaag
tcggtgcagctggtcatggagtacgtgcccctgggaagcctgcgggactacctgccccgg
cacagcgtgggcctggcgcagctgcttctcttcgcccagcagatctgtgagggcatggcc
taccttcacgcacagcactacgtgcaccgagacctggctgcccgcaacgtgctgctggac
aacgacaggctggtcaaaatcggggactttggcctagccaaggctgtgcctgaaggccat
gagtactaccgcgtgcgggaagatggggacagccccgtattctggtatgccccagagtgc
ctgaaggagtgtaagttctactatgcatctgacgtctggtccttcggggtcaccatgtat
gagctgctgacctactgtgactccagccagagccccccgtcgaaattcatcgagctcata
ggcctcacccaggggcagatgacggtgctgaggctcactgagctgctggaacgaggggag
aggctgccccggccagagagatgtccttgtgagatctatctcctcatgaagaactgctgg
gaggcagaggcttcattccgccccaccttccagaacctcatacccattctcaagacagtc
caggagaaataccaaggccaggctgcctccgtgttcagtgtgtgctga
DBGET
integrated database retrieval system
