KEGG   Zalophus californianus (California sea lion): 113916294
Entry
113916294         CDS       T07874                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA
  KO
K04513  Ras homolog gene family, member A
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca04014  Ras signaling pathway
zca04015  Rap1 signaling pathway
zca04022  cGMP-PKG signaling pathway
zca04024  cAMP signaling pathway
zca04062  Chemokine signaling pathway
zca04071  Sphingolipid signaling pathway
zca04072  Phospholipase D signaling pathway
zca04081  Hormone signaling
zca04144  Endocytosis
zca04150  mTOR signaling pathway
zca04270  Vascular smooth muscle contraction
zca04310  Wnt signaling pathway
zca04350  TGF-beta signaling pathway
zca04360  Axon guidance
zca04510  Focal adhesion
zca04517  IgSF CAM signaling
zca04520  Adherens junction
zca04530  Tight junction
zca04611  Platelet activation
zca04621  NOD-like receptor signaling pathway
zca04625  C-type lectin receptor signaling pathway
zca04660  T cell receptor signaling pathway
zca04670  Leukocyte transendothelial migration
zca04722  Neurotrophin signaling pathway
zca04810  Regulation of actin cytoskeleton
zca04921  Oxytocin signaling pathway
zca04928  Parathyroid hormone synthesis, secretion and action
zca04972  Pancreatic secretion
zca05100  Bacterial invasion of epithelial cells
zca05132  Salmonella infection
zca05133  Pertussis
zca05135  Yersinia infection
zca05152  Tuberculosis
zca05163  Human cytomegalovirus infection
zca05200  Pathways in cancer
zca05203  Viral carcinogenesis
zca05205  Proteoglycans in cancer
zca05206  MicroRNAs in cancer
zca05210  Colorectal cancer
zca05417  Lipid and atherosclerosis
zca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:zca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    113916294 (RHOA)
   04015 Rap1 signaling pathway
    113916294 (RHOA)
   04310 Wnt signaling pathway
    113916294 (RHOA)
   04350 TGF-beta signaling pathway
    113916294 (RHOA)
   04072 Phospholipase D signaling pathway
    113916294 (RHOA)
   04071 Sphingolipid signaling pathway
    113916294 (RHOA)
   04024 cAMP signaling pathway
    113916294 (RHOA)
   04022 cGMP-PKG signaling pathway
    113916294 (RHOA)
   04150 mTOR signaling pathway
    113916294 (RHOA)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    113916294 (RHOA)
   04517 IgSF CAM signaling
    113916294 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    113916294 (RHOA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    113916294 (RHOA)
   04520 Adherens junction
    113916294 (RHOA)
   04530 Tight junction
    113916294 (RHOA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    113916294 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    113916294 (RHOA)
   04621 NOD-like receptor signaling pathway
    113916294 (RHOA)
   04625 C-type lectin receptor signaling pathway
    113916294 (RHOA)
   04660 T cell receptor signaling pathway
    113916294 (RHOA)
   04670 Leukocyte transendothelial migration
    113916294 (RHOA)
   04062 Chemokine signaling pathway
    113916294 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    113916294 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    113916294 (RHOA)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    113916294 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    113916294 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    113916294 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    113916294 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113916294 (RHOA)
   05206 MicroRNAs in cancer
    113916294 (RHOA)
   05205 Proteoglycans in cancer
    113916294 (RHOA)
   05203 Viral carcinogenesis
    113916294 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    113916294 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    113916294 (RHOA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    113916294 (RHOA)
   05135 Yersinia infection
    113916294 (RHOA)
   05133 Pertussis
    113916294 (RHOA)
   05152 Tuberculosis
    113916294 (RHOA)
   05100 Bacterial invasion of epithelial cells
    113916294 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113916294 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    113916294 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:zca04131]
    113916294 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:zca04147]
    113916294 (RHOA)
   04031 GTP-binding proteins [BR:zca04031]
    113916294 (RHOA)
Membrane trafficking [BR:zca04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    113916294 (RHOA)
Exosome [BR:zca04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   113916294 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   113916294 (RHOA)
  Exosomal proteins of colorectal cancer cells
   113916294 (RHOA)
  Exosomal proteins of bladder cancer cells
   113916294 (RHOA)
GTP-binding proteins [BR:zca04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    113916294 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 113916294
NCBI-ProteinID: XP_027438147
UniProt: A0A6J2C6D8
LinkDB
Position
1:complement(18474260..18537054)
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatccggaagaaactggtgattgttggtgatggagcctgtggcaagacttgt
ttgctcatcgtctttagcaaggaccagttcccagaagtgtatgtacccacagtgtttgag
aactatgtggcagatattgaagttgatggaaagcaggtagagttggctttgtgggataca
gctgggcaggaagattatgatcgcttgaggcctctctcctatccggacactgatgttata
ctgatgtgtttctccattgacagccctgatagtttagaaaacatcccagaaaaatggacc
ccggaagtcaagcacttctgtcccaacgtgcccatcatcctggttgggaacaagaaggat
cttcggaatgatgagcacacaaggcgggagctagccaagatgaagcaggagccggtgaaa
ccggaagaaggcagagatatggcaaacaggattggcgctttcggttacatggagtgttca
gcaaagaccaaagatggagtgagggaagtttttgaaatggccacaagagctgctctgcaa
gccagacgtgggaagaaaaaatctgggtgccttgtcttgtga

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