KEGG   Zalophus californianus (California sea lion): 113916866
Entry
113916866         CDS       T07874                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca01522  Endocrine resistance
zca04010  MAPK signaling pathway
zca04014  Ras signaling pathway
zca04020  Calcium signaling pathway
zca04024  cAMP signaling pathway
zca04062  Chemokine signaling pathway
zca04081  Hormone signaling
zca04082  Neuroactive ligand signaling
zca04114  Oocyte meiosis
zca04140  Autophagy - animal
zca04211  Longevity regulating pathway
zca04213  Longevity regulating pathway - multiple species
zca04261  Adrenergic signaling in cardiomyocytes
zca04270  Vascular smooth muscle contraction
zca04310  Wnt signaling pathway
zca04340  Hedgehog signaling pathway
zca04371  Apelin signaling pathway
zca04530  Tight junction
zca04540  Gap junction
zca04611  Platelet activation
zca04713  Circadian entrainment
zca04714  Thermogenesis
zca04720  Long-term potentiation
zca04723  Retrograde endocannabinoid signaling
zca04724  Glutamatergic synapse
zca04725  Cholinergic synapse
zca04726  Serotonergic synapse
zca04727  GABAergic synapse
zca04728  Dopaminergic synapse
zca04740  Olfactory transduction
zca04742  Taste transduction
zca04750  Inflammatory mediator regulation of TRP channels
zca04910  Insulin signaling pathway
zca04911  Insulin secretion
zca04912  GnRH signaling pathway
zca04913  Ovarian steroidogenesis
zca04914  Progesterone-mediated oocyte maturation
zca04915  Estrogen signaling pathway
zca04916  Melanogenesis
zca04918  Thyroid hormone synthesis
zca04919  Thyroid hormone signaling pathway
zca04921  Oxytocin signaling pathway
zca04922  Glucagon signaling pathway
zca04923  Regulation of lipolysis in adipocytes
zca04924  Renin secretion
zca04925  Aldosterone synthesis and secretion
zca04926  Relaxin signaling pathway
zca04927  Cortisol synthesis and secretion
zca04928  Parathyroid hormone synthesis, secretion and action
zca04934  Cushing syndrome
zca04935  Growth hormone synthesis, secretion and action
zca04961  Endocrine and other factor-regulated calcium reabsorption
zca04962  Vasopressin-regulated water reabsorption
zca04970  Salivary secretion
zca04971  Gastric acid secretion
zca04976  Bile secretion
zca05012  Parkinson disease
zca05020  Prion disease
zca05030  Cocaine addiction
zca05031  Amphetamine addiction
zca05032  Morphine addiction
zca05034  Alcoholism
zca05146  Amoebiasis
zca05163  Human cytomegalovirus infection
zca05165  Human papillomavirus infection
zca05166  Human T-cell leukemia virus 1 infection
zca05200  Pathways in cancer
zca05203  Viral carcinogenesis
zca05205  Proteoglycans in cancer
zca05207  Chemical carcinogenesis - receptor activation
zca05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:zca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113916866 (PRKACA)
   04014 Ras signaling pathway
    113916866 (PRKACA)
   04310 Wnt signaling pathway
    113916866 (PRKACA)
   04340 Hedgehog signaling pathway
    113916866 (PRKACA)
   04371 Apelin signaling pathway
    113916866 (PRKACA)
   04020 Calcium signaling pathway
    113916866 (PRKACA)
   04024 cAMP signaling pathway
    113916866 (PRKACA)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    113916866 (PRKACA)
   04081 Hormone signaling
    113916866 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    113916866 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    113916866 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    113916866 (PRKACA)
   04540 Gap junction
    113916866 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    113916866 (PRKACA)
   04062 Chemokine signaling pathway
    113916866 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    113916866 (PRKACA)
   04910 Insulin signaling pathway
    113916866 (PRKACA)
   04922 Glucagon signaling pathway
    113916866 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    113916866 (PRKACA)
   04912 GnRH signaling pathway
    113916866 (PRKACA)
   04913 Ovarian steroidogenesis
    113916866 (PRKACA)
   04915 Estrogen signaling pathway
    113916866 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    113916866 (PRKACA)
   04921 Oxytocin signaling pathway
    113916866 (PRKACA)
   04926 Relaxin signaling pathway
    113916866 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    113916866 (PRKACA)
   04918 Thyroid hormone synthesis
    113916866 (PRKACA)
   04919 Thyroid hormone signaling pathway
    113916866 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    113916866 (PRKACA)
   04916 Melanogenesis
    113916866 (PRKACA)
   04924 Renin secretion
    113916866 (PRKACA)
   04925 Aldosterone synthesis and secretion
    113916866 (PRKACA)
   04927 Cortisol synthesis and secretion
    113916866 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    113916866 (PRKACA)
   04270 Vascular smooth muscle contraction
    113916866 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    113916866 (PRKACA)
   04971 Gastric acid secretion
    113916866 (PRKACA)
   04976 Bile secretion
    113916866 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    113916866 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    113916866 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    113916866 (PRKACA)
   04727 GABAergic synapse
    113916866 (PRKACA)
   04725 Cholinergic synapse
    113916866 (PRKACA)
   04728 Dopaminergic synapse
    113916866 (PRKACA)
   04726 Serotonergic synapse
    113916866 (PRKACA)
   04720 Long-term potentiation
    113916866 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    113916866 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    113916866 (PRKACA)
   04742 Taste transduction
    113916866 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    113916866 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    113916866 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    113916866 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    113916866 (PRKACA)
   04714 Thermogenesis
    113916866 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113916866 (PRKACA)
   05205 Proteoglycans in cancer
    113916866 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    113916866 (PRKACA)
   05203 Viral carcinogenesis
    113916866 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    113916866 (PRKACA)
   05163 Human cytomegalovirus infection
    113916866 (PRKACA)
   05165 Human papillomavirus infection
    113916866 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    113916866 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    113916866 (PRKACA)
   05020 Prion disease
    113916866 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    113916866 (PRKACA)
   05031 Amphetamine addiction
    113916866 (PRKACA)
   05032 Morphine addiction
    113916866 (PRKACA)
   05034 Alcoholism
    113916866 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    113916866 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    113916866 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    113916866 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:zca01001]
    113916866 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:zca03019]
    113916866 (PRKACA)
   03036 Chromosome and associated proteins [BR:zca03036]
    113916866 (PRKACA)
Enzymes [BR:zca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     113916866 (PRKACA)
Protein kinases [BR:zca01001]
 Serine/threonine kinases: AGC group
  PKA family
   113916866 (PRKACA)
Messenger RNA biogenesis [BR:zca03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     113916866 (PRKACA)
Chromosome and associated proteins [BR:zca03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    113916866 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C
Other DBs
NCBI-GeneID: 113916866
NCBI-ProteinID: XP_035578260
UniProt: A0A6P9EU47
LinkDB
Position
1:complement(9880125..9896772)
AA seq 351 aa
MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML
VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF
NT seq 1056 nt   +upstreamnt  +downstreamnt
atgggcaacgccgcagccgccaagaagggcagcgagcaggagagcgtgaaagagttctta
gccaaagccaaagaagattttcttaaaaaatgggaaaatcctgctcagaatacagcccat
ttggatcagtttgaacggatcaagaccctcggcacgggctcctttgggcgagtgatgctg
gtgaagcacaaggagaccgggaaccactttgccatgaagatcctcgacaaacagaaggtg
gtgaagctgaaacagatcgagcataccctgaacgaaaagcgcattctgcaagcggtcaac
tttccgttcctcgtcaaactcgagttctccttcaaggacaactcgaatttatacatggtc
atggagtatgtgcctggcggggagatgttctcgcacctgcggcggatcggaaggttcagt
gaaccacatgcccgcttctacgcggcccagatcgtcctgaccttcgagtacctgcactca
cttgacctcatctaccgggacctgaagccggagaacctcctcattgaccagcagggctac
attcaggtgacagacttcggttttgccaagcgtgtaaaaggccgcacctggaccttatgt
gggacccctgagtacctggccccggagatcatcctgagcaaaggctacaacaaggctgtg
gactggtgggccctgggggttctcatctacgagatggctgctggctacccgcccttcttc
gctgaccagcccatccagatctatgagaagattgtctctgggaaggtgcggttcccatcc
cacttcagctctgacctgaaggatctgctgcggaacctgctgcaggtggacctcaccaaa
cgcttcgggaacctcaagaacggggtcaacgacatcaagaaccacaagtggtttgccaca
actgactggatcgccatctaccagaggaaggtggaagctcccttcataccaaagtttaaa
ggccctggggacacgagtaattttgacgactatgaggaagaagagatccgagtctccatc
aatgagaagtgtggcaaggagtttactgagttttag

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