KEGG   Zalophus californianus (California sea lion): 113922232
Entry
113922232         CDS       T07874                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca01521  EGFR tyrosine kinase inhibitor resistance
zca01522  Endocrine resistance
zca04010  MAPK signaling pathway
zca04014  Ras signaling pathway
zca04015  Rap1 signaling pathway
zca04066  HIF-1 signaling pathway
zca04068  FoxO signaling pathway
zca04081  Hormone signaling
zca04114  Oocyte meiosis
zca04115  p53 signaling pathway
zca04150  mTOR signaling pathway
zca04151  PI3K-Akt signaling pathway
zca04152  AMPK signaling pathway
zca04211  Longevity regulating pathway
zca04213  Longevity regulating pathway - multiple species
zca04510  Focal adhesion
zca04550  Signaling pathways regulating pluripotency of stem cells
zca04730  Long-term depression
zca04750  Inflammatory mediator regulation of TRP channels
zca04913  Ovarian steroidogenesis
zca04914  Progesterone-mediated oocyte maturation
zca04935  Growth hormone synthesis, secretion and action
zca04960  Aldosterone-regulated sodium reabsorption
zca05200  Pathways in cancer
zca05202  Transcriptional misregulation in cancer
zca05205  Proteoglycans in cancer
zca05214  Glioma
zca05215  Prostate cancer
zca05218  Melanoma
zca05224  Breast cancer
zca05410  Hypertrophic cardiomyopathy
zca05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:zca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113922232 (IGF1)
   04014 Ras signaling pathway
    113922232 (IGF1)
   04015 Rap1 signaling pathway
    113922232 (IGF1)
   04066 HIF-1 signaling pathway
    113922232 (IGF1)
   04068 FoxO signaling pathway
    113922232 (IGF1)
   04151 PI3K-Akt signaling pathway
    113922232 (IGF1)
   04152 AMPK signaling pathway
    113922232 (IGF1)
   04150 mTOR signaling pathway
    113922232 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    113922232 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    113922232 (IGF1)
   04115 p53 signaling pathway
    113922232 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    113922232 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    113922232 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    113922232 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    113922232 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    113922232 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    113922232 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    113922232 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113922232 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    113922232 (IGF1)
   04213 Longevity regulating pathway - multiple species
    113922232 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113922232 (IGF1)
   05202 Transcriptional misregulation in cancer
    113922232 (IGF1)
   05205 Proteoglycans in cancer
    113922232 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    113922232 (IGF1)
   05218 Melanoma
    113922232 (IGF1)
   05215 Prostate cancer
    113922232 (IGF1)
   05224 Breast cancer
    113922232 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    113922232 (IGF1)
   05414 Dilated cardiomyopathy
    113922232 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    113922232 (IGF1)
   01522 Endocrine resistance
    113922232 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:zca04052]
    113922232 (IGF1)
Cytokines and neuropeptides [BR:zca04052]
 Cytokines
  Growth factors (RTK binding)
   113922232 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 113922232
NCBI-ProteinID: XP_027450006
UniProt: A0A6J2D2R4
LinkDB
Position
9:19360586..19437281
AA seq 187 aa
MGKISSLPTQLFKCCFCDFLKVKMHIMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYHPPSTTKKTKSQRRRKGGPKKRPGGEQKVGTEASQQMKGKKKEQR
RETGARN
NT seq 564 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacatcatgtcctcctcccatctcttctacctggccctgtgcttgctc
accttcaccagctccgccacagctggaccggagacgctctgtggggctgagttggtggac
gctcttcagttcgtgtgtggagacaggggtttttatttcaacaagcccacggggtatggc
tccagcagtcggagggcacctcagacaggcatcgtggacgagtgctgcttccggagctgt
gatttgaggaggctagagatgtactgcgcacccctcaagcctgccaagtctgcccgctca
gtccgtgcccagcgccacaccgacatgcccaaggctcagaagtatcatcccccatctacc
accaagaaaacgaagtctcagaggagaaggaaaggtgggccaaagaaacgcccaggaggg
gaacagaaggtggggacggaagcaagtcagcagatgaaaggaaagaagaaagagcagaga
agggagactggagctagaaactga

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