Zalophus californianus (California sea lion): 113925340
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Entry
113925340 CDS
T07874
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca01521
EGFR tyrosine kinase inhibitor resistance
zca04010
MAPK signaling pathway
zca04014
Ras signaling pathway
zca04015
Rap1 signaling pathway
zca04020
Calcium signaling pathway
zca04072
Phospholipase D signaling pathway
zca04144
Endocytosis
zca04151
PI3K-Akt signaling pathway
zca04510
Focal adhesion
zca04540
Gap junction
zca04630
JAK-STAT signaling pathway
zca04810
Regulation of actin cytoskeleton
zca05163
Human cytomegalovirus infection
zca05200
Pathways in cancer
zca05206
MicroRNAs in cancer
zca05214
Glioma
zca05215
Prostate cancer
zca05218
Melanoma
zca05230
Central carbon metabolism in cancer
zca05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113925340 (PDGFRA)
04014 Ras signaling pathway
113925340 (PDGFRA)
04015 Rap1 signaling pathway
113925340 (PDGFRA)
04630 JAK-STAT signaling pathway
113925340 (PDGFRA)
04020 Calcium signaling pathway
113925340 (PDGFRA)
04072 Phospholipase D signaling pathway
113925340 (PDGFRA)
04151 PI3K-Akt signaling pathway
113925340 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
113925340 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113925340 (PDGFRA)
04540 Gap junction
113925340 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
113925340 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113925340 (PDGFRA)
05206 MicroRNAs in cancer
113925340 (PDGFRA)
05230 Central carbon metabolism in cancer
113925340 (PDGFRA)
05231 Choline metabolism in cancer
113925340 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
113925340 (PDGFRA)
05218 Melanoma
113925340 (PDGFRA)
05215 Prostate cancer
113925340 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
113925340 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113925340 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113925340 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
zca04090
]
113925340 (PDGFRA)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
113925340 (PDGFRA)
Protein kinases [BR:
zca01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
113925340 (PDGFRA)
CD molecules [BR:
zca04090
]
Proteins
113925340 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
V-set
VEGFR-1-like_Ig-like
Herpes_gE
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
113925340
NCBI-ProteinID:
XP_027455810
UniProt:
A0A6J2DJG4
LinkDB
All DBs
Position
2:42698682..42744384
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSLPALLILGCLLRGPSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTEETEIEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLRSNDGVVHASYDSRQGFNG
TFSVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLRVPEATVKDSGDYECAARQATKEVK
EMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIERIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWAILANNISNIITEVHPRD
RSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKEELDIFGLNPADDSTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVEHLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNTYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccttccggccctcctgatcttaggctgtctcctcagagggcccagccta
atcctctgccagctttcattaccgtctatcctcccgaacgaaaatgaaaaggtcgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaaccccaatgtggaaatcagaaatgaggaaaacaacagtggcctt
tttgtgaccgtgctggaggtggtcaacgcgtcggcggcgcacacaggcttgtacacttgc
tattacaatcacactcagacggaggaaaccgagatcgaaggcaggcacatctacatctac
gtgccagacccagatgtagcctttgtacctctaggaatgacagattatttagtcatcgtg
gaggatgatgattctgccatcataccttgtcgcacaactgatcccgagactccggtcacc
ttgcgcagcaatgatggggtggtgcatgcctcctatgacagcagacagggctttaatggg
accttcagcgttgggccctatatctgcgaagccaccgtcagagggaagaagttccagacc
atcccatttaatgtttatgctttaaaagcaacatcagaacttgatctagaaatggaagct
cttaaaaccgtgtataagtcaggggagacgattgtggtcacctgcgccgtctttaacaat
gaggtggttgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcaccatg
ctggaggaaatcaaggtcccgtccatcaaattggtgtacactctgagggtccccgaggcc
acggtgaaagatagtggagattatgaatgtgctgcccgccaggccaccaaggaggtcaaa
gagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaacccaac
ttcagcccgttggaagctgttgacctacatgaagtcaaacattttgtggtggacgtgcag
gcctacccccctcccaggatatcctggctgaaggacaacctgactctgattgaaaatctc
acggagatcaccacggacatagaaaggattcaggaaataaggtatcggagcaaattaaag
ctgatccgcgctaaggaggaagacagtggccattacacgattgtcgttcaaaatgaagac
gacgtgaagagctatactttcgaactcttaactcaagttccctcgtctattctggacttg
gttgatgaccaccatggctctacggggggacagaccgtgagatgcaccgctgaagggacg
cctcttcctgatattgagtggatgatctgcaaggatattaagaagtgtaataatgaaact
tcatgggcgattttggccaacaatatctcaaacattatcacggaggtccacccccgagat
aggagtactgtggagggccgagtgacattcaccagggtggaggagaccatcgctgttcga
tgtctggccaagaatctccttggggccgagagccgagagctgaagctggtggctcccacg
ctgcgttctgaactcaccgtcgccgctgcggtcctcgtgctgttggtgattgtgatcatc
tcacttattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctggagg
gtcattgaatccatcagccctgatggacatgaatatatttacgtggacccgatgcagctg
ccttatgactcaagatgggagtttccaagggatggactcgtgcttggtcgtatcctggga
tctggtgcgtttgggaaagtggttgaaggaactgcctatgggttaagccgctcccagcct
gtcatgaaagtggcagtgaagatgctaaaacccacagccagatccagtgagaaacaagct
ctcatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaacttg
ctgggagcctgtaccaagtcaggccctatttacatcatcaccgagtactgcttctatggg
gatttggtcaactatttgcataagaatagggatagcttcctgagccgccacccggagaag
ccaaaggaagagctggacattttcggattgaaccctgccgatgacagcacacggagttat
gttattttatcttttgaaaacaatggtgactacatggacatgaagcaagctgacaccaca
cagtatgtccccatgctggaaaggaaagaggtttctaaatactcggacatccagagatcg
ctgtatgaccgcccagcctcgtataagaagaaatctatgttagactcggaagtcaaaaac
ctcctttcagacgataactcagaaggccttactttgttggacttgttgagctttacctat
caagttgcgcgaggaatggaatttttggcttcaaaaaattgtgtccatcgggacctggct
gctcgaaatgtcctcctggcgcaggggaaaatcgtgaagatctgtgacttcggcctggcc
agagacatcatgcatgattcaaactacgtgtccaaaggcagtacctttctccccgtgaag
tggatggcccctgagagcatcttcgacaacctctacaccacgctgagtgacgtgtggtcc
tacggcattctgctctgggagatcttttcccttggtggcacaccctaccctggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgaccac
gccaccagcgaagtctatgagatcatggtgaagtgctggcacagcgagccggagaagaga
ccctccttctaccacctgagtgagattgtggagcatctgctgcctggacagtataagaag
agttatgaaaagattcatctggacttcctgaagagcgaccaccccgccgtggcgcgcatg
cgcgtggactcggacaacacctacattggcgtcacctacaaaaacgaggaagacaagctg
aaggactgggagggcagcctggacgagcagaggctgagcgcggacagcggctacatcatc
cccctgcccgacatcgaccctgttcctgaggaggaagacctgggcaagaggaacagacac
agctcacagacctcagaagagagcgctatcgagacaggttccagcagctctactttcatc
aagagagaggatgaaaccatcgaggatatcgacatgatggacgacattggcatagactcc
tcagacctggtagaggacagcttcctgtga
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