Zalophus californianus (California sea lion): 113926693
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Entry
113926693 CDS
T07874
Symbol
PDE10A
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X2
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca00230
Purine metabolism
zca01100
Metabolic pathways
zca04024
cAMP signaling pathway
zca05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
113926693 (PDE10A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
113926693 (PDE10A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
113926693 (PDE10A)
Enzymes [BR:
zca01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
113926693 (PDE10A)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
113926693 (PDE10A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
113926693
NCBI-ProteinID:
XP_027457761
UniProt:
A0A6J2DPU1
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Position
7:3394643..3977102
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AA seq
926 aa
AA seq
DB search
MDRSSLVPRVLHAASLETPPGGGVGKEEYHTRFRVVSPFPEKICAKSRVPGAFGICLLSG
AEASVLGEVPNLGHRPRLATCFAQFSMEPWTHSVPGRLAYFFPPFPSLFFKHTNLKRSGE
QIRTSAHFGGPSLTKPGAYVEEPGPIRADAICRWGLTDEKVKAYLSLHPQVLDEFVSESV
SAETVEKWLKRKNNKPEDESAPKEVSRYQDTNMQGVVYELNSYIEQRLDTGGDNQLLLYE
LSSIIKIATKADGFALYFLGECNNSLCVFTPPGIKEGKPRLIPAGPIAQGTTISAYVAKS
RKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIVTAIGDLIGILELYRHWGKEAFCMS
HQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLLDVSKTYFDNIVAIDSLLEHIMIYA
KNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKPIFKKTKEIRFSIEKGIAGQVARTG
EVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVSRGSVIGVVQMVNKISGSAFSKTDE
NNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEKLSYHSICTAEEWQGLMRFNLPVRL
CKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWK
HAVTVAHCMYAILQNNHGLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYST
STMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEM
YQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGI
QPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQIFPPTEPLLKACRNNLSQWEKVIRG
EESAVWISAQPGAHGPSEKLPVKIED
NT seq
2781 nt
NT seq
+upstream
nt +downstream
nt
atggaccggtcttcgttggtgcctagagtgctccacgcggcttccctggagacccccccg
ggggggggggtagggaaagaagaataccacactcggtttagagttgtctccccctttcct
gagaagatctgcgcgaaatccagggtgcccggagcctttggaatatgcctgctgagcgga
gcagaagcgagcgttcttggagaggtcccgaacttgggccaccggcctcgcttggcaact
tgctttgcgcagttctcaatggagccctggacccacagtgttcctggccggttggcttat
tttttccctccgttcccctctctcttttttaaacataccaacttgaaacgaagcggagag
cagatccgcacttcagcacactttggcggcccatctctaactaaaccaggagcctacgtt
gaagaacctggacccatcagggctgatgcaatctgtagatggggtttgacagatgaaaaa
gtgaaggcatatctttctcttcatccccaggtgttagacgaatttgtatctgaaagtgtt
agtgcagagactgtagaaaaatggctgaagaggaaaaacaacaaaccagaagatgaatcg
gctcctaaggaagtcagcaggtaccaagacacgaatatgcagggcgttgtgtatgaacta
aacagctacatagaacaacggttggatacaggaggagacaaccagctactcctctatgaa
ttgagtagcatcattaaaatagccacaaaagctgatggatttgcactgtatttccttgga
gagtgcaataatagtctgtgcgtgttcactccacctggaatcaaggaaggaaaaccccgg
ctcatccctgctgggcccattgcccagggcaccaccatctctgcctacgtggccaagtcc
agaaaaacgttgctagtggaagacatccttggggatgaacgatttccaagaggtactgga
ctggagtcagggactcgcatccagtctgttctttgtttaccaattgtcactgcaattggt
gacttgattggtatcctcgagctgtatcggcactggggcaaagaagccttctgtatgagt
catcaggaggttgcaacagcaaatcttgcctgggcttcagtagcaatacatcaggtgcag
gtatgcagaggccttgctaaacagactgaattgaatgacttcctacttgatgtatcaaag
acatattttgataacatagtcgcaatagactctctacttgaacacataatgatatatgca
aaaaatctggtgaatgccgatcgttgtgcacttttccaggtagaccataagaacaaggag
ttatattcagacctttttgatattggagaggaaaaggaaggaaaacctatcttcaagaag
accaaagaaataagattttcaattgagaaaggaattgctggtcaggtagcaagaacaggg
gaagtcctgaacattccagatgcctatgcagacccacgctttaacagggaagtggacttg
tacacaggctacaccacccggaatatcctgtgcatgcccatcgtgagccggggaagcgtg
atcggtgtggtgcagatggtgaacaaaataagcggcagtgccttctcgaaaacggacgaa
aacaacttcaagatgtttgccgtcttctgtgctttagccttacactgtgccaatatgtat
cacagaatccgtcattccgagtgcatttaccgggtgactatggagaagctgtcctaccat
agcatttgtacggcggaggagtggcagggcctcatgcgcttcaacctccccgtgcgcctc
tgcaaagaaattgaactattccactttgacattgggccttttgaaaacatgtggcctgga
atttttgtctacatggtccatcggtcctgtgggacatcctgctttgagcttgaaaagttg
tgtcgttttattatgtctgtgaagaaaaactatcggcgggttccttatcacaactggaag
cacgccgtcactgtggctcactgcatgtacgccattctccagaacaaccacgggctcttc
accgaccttgagcgcaaaggactgctaatcgcgtgtctgtgccatgacctggaccacagg
ggtttcagtaacagctacctgcagaaattcgaccaccctctggcagccctctattccact
tccaccatggagcagcatcacttctcccagacagtgtccatcctccagttggaagggcac
aatatcttctccaccctgagctccagtgaatatgaacaggtgctcgagatcatccgcaaa
gctatcattgccacagaccttgctttgtactttggaaacagaaaacagttggaggagatg
taccagaccggatcgctaaaccttaataatcaatcacatagagatcgtgtcattggtttg
atgatgactgcctgtgatctttgttctgtaacaaaactatggccggttacaaaattgaca
gcaaatgatatatatgcagagttctgggctgagggcgatgagatgaaaaagttgggaata
caacctattcccatgatggacagagacaagaaggacgaggtcccacaaggccagctgggg
ttctacaacgctgtggctatcccctgctacaccaccctcacccagatcttcccgcccaca
gagcctctcctcaaagcatgcaggaataacctcagccagtgggagaaggtgatccgaggg
gaggagagtgcggtatggatctcggcccagccaggggcccacgggccctcagagaagttg
cccgtgaagatcgaagactga
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