Zalophus californianus (California sea lion): 113933431
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Entry
113933431 CDS
T07874
Symbol
TSC2
Name
(RefSeq) tuberin isoform X1
KO
K07207
tuberous sclerosis 2
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04072
Phospholipase D signaling pathway
zca04115
p53 signaling pathway
zca04140
Autophagy - animal
zca04150
mTOR signaling pathway
zca04151
PI3K-Akt signaling pathway
zca04152
AMPK signaling pathway
zca04211
Longevity regulating pathway
zca04218
Cellular senescence
zca04714
Thermogenesis
zca04910
Insulin signaling pathway
zca04919
Thyroid hormone signaling pathway
zca05163
Human cytomegalovirus infection
zca05165
Human papillomavirus infection
zca05168
Herpes simplex virus 1 infection
zca05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
113933431 (TSC2)
04151 PI3K-Akt signaling pathway
113933431 (TSC2)
04152 AMPK signaling pathway
113933431 (TSC2)
04150 mTOR signaling pathway
113933431 (TSC2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
113933431 (TSC2)
09143 Cell growth and death
04115 p53 signaling pathway
113933431 (TSC2)
04218 Cellular senescence
113933431 (TSC2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
113933431 (TSC2)
04919 Thyroid hormone signaling pathway
113933431 (TSC2)
09149 Aging
04211 Longevity regulating pathway
113933431 (TSC2)
09159 Environmental adaptation
04714 Thermogenesis
113933431 (TSC2)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
113933431 (TSC2)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
113933431 (TSC2)
05163 Human cytomegalovirus infection
113933431 (TSC2)
05165 Human papillomavirus infection
113933431 (TSC2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
zca01009
]
113933431 (TSC2)
Protein phosphatases and associated proteins [BR:
zca01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
113933431 (TSC2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Tuberin
DUF3384
Rap_GAP
HEAT
Cnd1
Motif
Other DBs
NCBI-GeneID:
113933431
NCBI-ProteinID:
XP_027469309
UniProt:
A0A6J2EK05
LinkDB
All DBs
Position
10:71055212..71088347
Genome browser
AA seq
1813 aa
AA seq
DB search
MAKPTSKDSGLKEKFRILLGLGTPRPNPRSAEGKQTEFIITADILRELSVECGINNRIRV
IGQICEVAKTKKFEEHAVEALWKAVADLLHPERPPEARHAVLALLKAIVQGQGDRLGVLR
ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAGFVLQWMDIGLSSEFLLVL
VNLVKFNSCYLDEYIASMVHMICLLCVQTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI
VTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMEDAPLLRGAVFFVG
MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRRELQAVAWDI
LLNIMERLLQQLQSLDSPELRAIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPE
SSLLNLITYRAQSIHPAKDGWIHNLQLLMERFFRNESRSAVRIKVLDVLSFVLLINRQFY
EEELISSVVISQLSHVPEDKDPQVRKLATQLLVDLAEGCHTHHFNSLLDIVEKVIARSLS
PPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYALPASHAVRVYETLVSHMELHYRR
DYTLPIASSIRLQAFDFLLLLRADSLHRLGLPSKDGAVRFSPYCVCDAMEPERGPEKKAS
GPLSPPTGPPGSAPVGPAVRLGSLPYSLLFRVLLQCLKQEADWKVLKLVLSKLPESLRYK
VLIFTSPCSVDQLSSALCSVLSGPRTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL
DKTRQREMVYCLEQGLIHRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA
IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC
RLPFRKDFVPFITKGLRSNVLLPFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNS
PPVKEFKESPAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHL
ELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSL
LGLDSGELQGGPESSSDPGAHVRQTKEAPAKLESQAGQQVCRGARDRVRSMSGGHGLRVG
ALDTPASHFPGGPTSPGAQTALTSKSERASAGTQFPVQEKTSLAAYVPLLTQGWAEILVR
RPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKERRDTALYKSLSVPAAGS
SKPPPPPRSNTVASFSSLCQSSCQAKLHRSISWADSAVVPEEGSTSETHLSAEPMELEDF
EATLGTDRRGDRAEAYSRSSSSSSQEEKFPAEELAAGGIPIERAVSSEGTRPSVELSFQP
SQPLSKSSSSPELQTLQDVLGDPGDKTDVGRLSPEAKARSQSGILDGAGASWSAPGAESR
GRGPAQPEGPLPSSCPRSPSGLRPRGYTISDSAPSRRGKRAEKDAFKSRAGASNTEKVPG
INPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSS
SELAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQ
AVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIRGQFNFVHVIITPL
DYECNLVTLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIY
PSKWIARLRHIKRLRHRIREEAHYSNPSLPLMQMHPPGHAKAPAQAPAEPTPTYETGQRK
RLISSVDDFTEFV
NT seq
5442 nt
NT seq
+upstream
nt +downstream
nt
atggccaagccaacaagcaaagattcaggcttgaaggagaagttcaggattctcttggga
ctgggaaccccgaggccaaaccccaggtctgcagagggcaaacagacggagtttatcatc
acggcggacatcctgagagaactgagtgttgaatgtggtatcaacaatcgcatccgggtg
atagggcagatctgtgaagttgcaaaaacgaagaaatttgaagagcatgccgtggaggcg
ctgtggaaggccgtggcggacctgctgcacccggagcggcccccggaggcccggcatgcg
gtgctggctctgctgaaggccatcgtgcaggggcagggggaccggttgggtgttctcagg
gccctcttcttcaaggtcataaaggattacccctctaatgaagacctccacgagagactg
gaagtgttcaaggccctcacggacaatgggagacacatcacctacttggaagaagaactg
gctgggtttgtcctgcagtggatggacatcggcctatcctcagaattcctcctggtgctt
gtgaacttggtcaagttcaacagctgctacctggatgaatatattgcatcaatggtccac
atgatctgcctgttgtgcgtccagaccgtgtcgtccgtggacatagaggtctccctgcag
gtgctggatgccgtggtctgttacaactgcctgccggctgagagcctccccctgttcatt
gtcaccctctgccgtaccatcaatgtcaaggagctttgtgagccttgctggaagctgatg
cgtaacctcctgggcacccacctgggccacagtgccatctacaacatgtgtcgtatcatg
gaggacagagcctacatggaagatgccccactgctgagaggggctgtgttctttgtgggc
atggcgctctggggagcgcaccgactctactccctcaagaactccccgacgtccgtgctg
ccatcgttttatgaggccatgacctgtccaaacgaggtggtgtcctacgaaatcgtgctt
tctataaccagactcatcaagaagtaccgcagggagctccaggctgtggcgtgggacatc
ctgctgaacatcatggagcgcctgcttcagcagctccagagcctggacagcccagagctc
agagctatcgtccacgacctgctgaccacagtggaagagctgtgtgaccagaacgagttc
cacggctctcaggagagatactttgagctggttgagcgatgcgcagaccagaggcctgag
tcctccctcttaaacttaataacctacagggcacagtcaatccatccggcgaaggacggc
tggattcacaacctgcagttgctgatggagagattcttcaggaatgaatcccgcagtgcc
gttcgcatcaaggtgctggatgtcctgtccttcgtgctgctcatcaacaggcagttctat
gaggaggagctgatcagctcagtggtcatctcccagctctcccacgtccctgaggacaaa
gacccccaagtccggaaactggccacccagttgctggtggacctggccgaaggctgtcat
acccaccacttcaacagcctgctggacattgtggaaaaggtgattgcccgctccctttct
ccaccccctgagctggaggagagagatgtggcggcgtactcagcctccttagaggatgtg
aagaccgccgtcttggggctcctggtcatccttcagaccaagctgtacgccttgcctgcc
agccacgcggtgcgtgtgtacgagacgctcgtcagccacatggagctgcattacaggcgc
gactacaccctacccatcgcaagcagcatccggttgcaggccttcgacttcctgctgctg
ctgagggccgactcactgcaccgcctcggcctgcccagcaaggatggggccgtgaggttc
agcccttactgcgtctgtgacgccatggagccggagaggggcccggagaagaaggccagc
ggccccctgtcgcctcccaccgggccgcctggctctgcgcccgtaggccccgcggtgcgg
ctcggctctctgccctactccctgctcttccgcgtcctcctacagtgcttgaagcaggag
gcagactggaaggtgctgaagctcgtgctcagcaagctgcccgagtccctgcgctacaag
gtgctcatcttcacgtctccgtgcagcgtcgaccagctgtcttccgccctctgctccgtg
ctttcaggtcccagaaccctggagcggcttcgaggcaccccggaaggattttccagaacc
gacctgcatctggctgtggttcctgtgctgacggcgctgatctcttaccataattacttg
gacaagaccagacagcgggagatggtgtactgcctggagcaaggcctgatccaccgctgt
gctagccagtgtgtggtggcgctggccatctgcagcgtggagatgcccgacatcatcatt
aaggcgcttcccgtcctggtcgtgaagctcacacacatctcagccacggccagcatggcc
attccacttctcgaattcttatcaactctggcccggctgccccacctctaccggaacttt
gcagctgagcagtacgcgagcgtctttgccatttccctgccttacaccaacccctccaag
tttaatcagtacatcgtgtgcttggcccatcatgttatagccatgtggttcattagatgc
cgcctgcccttccggaaggattttgttccttttatcactaagggcttgcgctccaacgtt
ctcctgcccttcgatgacacccctgagaaggacagcttcagagctcgaagcaccagtctc
aacgagaggcccaagagtttgaggatagccagaccccccaaacaaggcttgaataactct
ccacccgtgaaagaattcaaggagagccctgcagccgaggccttccggtgccgcagcatc
agtgtgtctgaacatgtggtccgcagcaggatccagacgtccctcaccagcgccagcttg
gggtctgcagatgagaattcgatggcccaggctgatgacaacttgaaaaatctccacctg
gagctcacagaaacatgtctggacatgatggccagatacgtgttctccaatttcacagcg
gttcccaagaggtcacctgtgggcgagttcctcctggctggcggcaggaccaaaacctgg
ctggttgggaacaagcttgttaccgtgacaacgagcgtggggaccgggacccggtcgctg
ctgggcttggattcaggagagctgcagggtggccccgagtcgagctcagaccctggcgcg
catgtgagacagaccaaggaggcgcctgccaagctggagtcccaggctgggcagcaggtg
tgccgcggggcccgggaccgggtccgctccatgtccgggggccatggccttcgtgttggt
gccctggacactccagcctcccacttcccgggtggccccacttccccgggtgcacagact
gctctcaccagcaagtctgagagggcgtcagctggtacccagttcccagtgcaggagaag
acgagcctggcagcctatgtccccctgctgacccagggctgggcagagatcctggtccgg
aggcccacagggaacaccagttggctgatgagcctggagaacccactcagccccttctcc
tcagacatcaacaacatgcccctgcaggagctgtccaacgcgctcatggccgccgagcgc
tttaaggagcgtcgcgacacagctctgtacaagtcgctgtcggtgccggcggcgggctca
tccaagccccctccacccccgcggtctaacacggtggcctctttctcctccctgtgccag
tccagttgccaagcaaagctgcacaggagcatttcctgggcagactcggcagtggttccg
gaggaggggagcacaagcgagactcatttgtccgcggagcccatggagttggaggacttt
gaggcgacgctaggcacagaccggcgtggtgaccgtgctgaggcttacagcaggtcatct
tcaagctccagccaagaggagaagttccctgcagaggagctggcggctggagggatcccc
atcgagcgggccgtctcttctgagggcacccggccttctgtggagctctccttccagccc
tcccagcccctcagcaagtccagctcctcgcctgagctgcagaccctgcaggacgtgctg
ggggaccctggagacaagactgacgttggccggctgagccctgaggccaaggcccggtcg
cagtccgggatcctggacggggcaggtgcctcctggtcagccccaggcgcagagagccgg
ggccggggccccgcgcagcccgagggtcccttgccttctagctgcccccgctcccccagt
ggcctgcggcccagaggctacaccatctctgattcggccccatcacgcagaggcaagaga
gcagagaaggacgccttcaagagcagagcgggggcctccaatactgagaaggtgccaggc
atcaatcccagttttgtgttcctgcaactctaccattcacctttctttggtgacgagtcc
aacaagcccatccttctacccaatgagtccttcgagcggtcagtgcagcttctcgaccag
attccatcctatgacacgcacaagattgccgtcctgtacgtgggagaaggccagagcagc
agcgagctggccatcctgtccaatgagcacggctcgtacaggtacacggagttcctgacc
ggcctgggcaagctcatcgaactcaaggactgccagccggacaaggtgtacctggggggt
ctggatgtgtgtggggaggacggccagttcacctactgttggcacgacgacatcatgcaa
gctgtcttccacatcgccaccctgatgcccaccaaggacgtggacaagcaccgctgtgac
aagaagcgtcatctgggcaatgacttcgtgtccattgtgtacaatgactccggcgaggac
ttcaagctgggcaccatcagaggtcagttcaactttgtccatgtcatcatcacccccctg
gactatgagtgcaacctggtgaccctgcagtgcaggaaagacatggagggtctcgtggat
accagcgtggccaagatcgtgtcagaccgcaacctgccttttgtggcccgtcagatggct
ctgcacgcaaacatggcctcacaggtacatcacagccgctccaaccccactgacatctac
ccctccaagtggatcgccaggctccgccacatcaagcggctccgccaccggatccgggag
gaagcccactattccaaccccagcctgcccctgatgcagatgcaccccccgggccacgcc
aaagcccctgctcaggcgccggcagagcccacgcccacgtatgagacgggccagcggaag
cgcctcatctcctcagtggatgacttcacggagttcgtgtga
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integrated database retrieval system
