Zalophus californianus (California sea lion): 113934243
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Entry
113934243 CDS
T07874
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca00790
Folate biosynthesis
zca01100
Metabolic pathways
zca01240
Biosynthesis of cofactors
zca01523
Antifolate resistance
zca04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
113934243 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
113934243 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
113934243 (FPGS)
Enzymes [BR:
zca01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
113934243 (FPGS)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
113934243
NCBI-ProteinID:
XP_027470623
UniProt:
A0A6J2EYG3
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Position
13:complement(7839490..7859840)
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AA seq
620 aa
AA seq
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MRAGTYLLNPRRSRLDRGALTHESLCAQPRWGVGSPGMKRARSLATLWPAAEKVRWRAAM
ERPGPSASPLSAKTASFQDAVRTLNTLQTNAGYLEQVKRQRGDPQTQLEAMKLYLARSGL
QVEDLDQLNIIHVTGTKGKGSTCAFTERVLRSYGLKTGFFSSPHLVQVRERIRINGQPIS
PELFTKHFWHLYHRLEETKDGSSCVSMPAYFRFLTLMAFHIFLQEKVDLAVVEVGIGGAY
DCTNIIRKPVVCGVSSLGIDHTSLLGDTVEEIAWQKGGIFKHGVPAFTVLQPDGPLAVLR
DRAQQISCPLYLCPPLEALEEGGPPLTLGLDGEHQRFNAALALQLARCWLQQKGHQGLGE
LKVSRPSVLRQMPLAPVFQPTPHMRHGLRDTEWLGRTQVLRRGPLTWYLDGAHTTSSVQA
CVRWFRQALHRGQRPSRGPEVRILLFNSTGDRDSAALLKLLQPCQFDYAVFCPNLTEVSS
AGNADQQNFMVTLDQVLLRCLAHQQYWSHLAEAQASPDLWSPPSPEPGEPTSSLLASHPP
CTHSTSSLVFSCISHALQWISQGRDPVLQPPSPPQGLLAHPVAGSGASVLREAAAIHVLV
TGSLHLVGGVLKLLEPALSQ
NT seq
1863 nt
NT seq
+upstream
nt +downstream
nt
atgagagcaggcacctatctgctgaaccccaggcggagcaggcttgacagaggtgccctc
acccatgaatcactttgtgcccagccccgctggggtgtgggaagcccggggatgaaacgt
gccaggtccctggcaaccctctggccggcggctgagaaggtgaggtggagagcagccatg
gagcgaccaggcccatctgcgagtcctttgtcagctaaaaccgcctccttccaggatgct
gtgcgcacactgaacaccctgcagaccaatgctggttacctggagcaggtaaagcgccag
cggggtgaccctcagacacagctggaagccatgaagctgtacctggcccggagtgggctg
caggtggaagacttggaccagctgaacatcattcacgtcactgggaccaaggggaagggt
tccacgtgtgccttcaccgaacgtgtgctccgcagctatggcctgaagacaggattcttt
agctctccccacctggtgcaggtgcgggagcggatccgcatcaacgggcagcccataagc
cccgagctcttcaccaagcacttctggcacctctaccaccggctggaggagaccaaggac
ggcagcagctgtgtctccatgcctgcctacttccgcttcctcacactcatggccttccac
atcttcctccaagagaaggtggacctggcagtggtggaagtgggcattggtggcgcttac
gactgcaccaacatcatcaggaagcctgtggtatgtggcgtctcctctcttggcatcgac
cacaccagccttctgggggacacagtggaggagatcgcatggcagaaagggggcatcttc
aagcatggcgtccctgccttcacggtgctccagcctgatggtcccctggcagtgctgcgg
gaccgtgcccagcagatctcctgtcctctctacctgtgcccaccactggaagccctggag
gaaggggggccaccgctgaccctgggcctggacggagagcaccagcggttcaacgccgcc
ttggccttgcagctggctcgctgctggctgcagcaaaagggccaccagggcctcggggag
ctgaaggtgtctcggcccagcgtcttgcggcagatgcccctggcacccgtgttccagccc
acgccccacatgcggcatgggcttcgggacacggagtggctgggccggacgcaggtgctg
cggcgcgggcccctcacctggtacctggacggcgcgcacaccaccagcagcgtgcaggcc
tgcgtgcgctggttccgccaggcgctgcaccgcggccagaggcccagccgcggccctgag
gtacgcatcttgctcttcaactccaccggggaccgggattccgcggccctgctgaagctg
ctgcagccctgtcagtttgactatgctgttttctgccctaacctgacagaggtgtcgtct
gctggcaacgcagaccagcagaacttcatggtgaccctggaccaggtgctgctccgttgc
cttgcacatcaacagtactggagccacctggctgaggcgcaggccagcccagacctctgg
agcccccccagcccggagcctggtgagcccacatcctcgctgctggcttcccacccaccc
tgcacccatagcaccagctccctcgtcttcagctgcatctcccacgccctgcagtggatc
agccaaggccgggaccctgtccttcagccacccagtcccccacagggcctccttgcccac
cctgtggcaggcagcggggccagtgtgctccgtgaggctgccgccatccatgtactggtc
acgggcagcttgcacctggtgggcggcgtcctgaagctgctggagcctgccctgtcccag
taa
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