Zalophus californianus (California sea lion): 113934773
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Entry
113934773 CDS
T07874
Symbol
SETX
Name
(RefSeq) LOW QUALITY PROTEIN: probable helicase senataxin
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
113934773 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
zca03021
]
113934773 (SETX)
Enzymes [BR:
zca01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
113934773 (SETX)
5.6.2.5 RNA 5'-3' helicase
113934773 (SETX)
Transcription machinery [BR:
zca03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
113934773 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
nSTAND3
AAA_22
ResIII
SLFN-g3_helicase
Helicase_RecD
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
113934773
NCBI-ProteinID:
XP_027472116
UniProt:
A0A6J2EV66
LinkDB
All DBs
Position
13:4255447..4339458
Genome browser
AA seq
2692 aa
AA seq
DB search
MSTCCWCTPGGISTVDFLQRYASETHSSEFQTADEDLCYCLECVAEYHKARDDLPFLHEV
LWELETLRLINYFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCFMVILDRL
GSKVWGQRIDPIEAFQTIINNVSYNKEIQNIRNSSVRTKLEPESYLDDATCSQIVYNYNP
EKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMDL
KDLGVAYIVEVIHHLHSEVKDVLNQTDAMCDKVTEFFLLILVSVIELHRNKKCLHLLWVS
SQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLACVQLIRS
LLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIKNIKVKVPQ
CNTFVDLSPAGKSSPASYSKEESEQIERRSNKDLHCLENSSPTFSKEPMKAEAYQIQENI
LIKASNTIEEDNEQNYMKDWKLEDHLSAESCIKKSSKNVFTERAQDQVKISTGKQKSVKE
NCTSRNVLQNCTSRNGPERGYDRGIIMSTRLLTDSSTDSLEKACTSNEDLSFKDDALGKT
AKSKTKAHKDEICAKLSHVIKKQHRKSTLINNTGNLEENVTVSNIDSFYSRKDSGGQKGD
GFMHNLSLDPLGILDEKNGEQKSQKSLLLKKKQLKSEELEIFSSHENSYQIQECHDDKDL
VSFTEVTNTFVRKTSPFKDPVTVLESKDKEISKNTSQMSSHLREQAPGLSPQSDTLTDSQ
IDRDLHKLSLIAQASVIKFPSDSTQKSSSQLQRRVKDDRRCFPADQNNTGEACRGQIIII
SDSDDDDDDDEGILGLEKRIKQDKIGIKKECPEQHTSIASTNVEKSLIKEEETKSLLQFE
ESDSQFFEFESPCEVFSVWQDQEPDKNSVQESEKNSCSTDIADITNDWGYETDYVSEEVI
KKVAEGIEKHTEPQGSISVGEFCEIEVKKRKRKRFEKPMAEGPLRPSPSDRNEDQPDILN
ERGLTENDFKSMDLRTVSPTSGVQRDKDTTVSLKKSSPKLRTYSKPIRRVPLSKTPKKTH
SDTKKGQNKSSNYISCRTTPAIVPPKKFRQCPEPTLTVEKLGLKKAPRRAFELSQRSLEC
LVRLRHHGKTVGVVDTSKKTKLISPQTLSVRNNKKLLTSQDLQLRRQMRPKSQQNRQGLL
DYENKDTTRAGLCTAQNSDIPVPESDGSDYSYKGGTEVVANSTGKQTKCVSSEPEPMKTK
YVSQVTNDACLLNQSAAVVLNGRIPTNEIIVSASADPLGGGDRTVHHLELATLKDGEPES
NSDTEDENIFLTQHDPEDMDLCSQMENGNEKLIEVVHGKDTAQVEEDSVSQPQLESWNST
KCKYKDCVETPKNQGDYCSKHCEAKAADEDVFRKPGLPLSASKPSRPSTAKIFSSSSTSR
IANLSKSLESTSALPPALKNKSNGAQAVLKVPQPASLVSPKPGGEVKSLGNVFHPQTPSN
SSRQGYKLTFGESKSFSASSPVHILLSSQSISDTFVKEVLKWKYEMFVNFDQCGPPASLC
QSISRPVPVRFQDCGDYFNVFFPLMVLNTFETVAQEWISSPNKEKFYQLHLRKFPADYKK
YWEFVVHLEECELAKQVHPKENDLVFLVPERQNGEKKDTERNRMQDLREYHCGYIHKFRR
TSVMRNGKSECSLSIQTQDNLPVNLNELVKCVVISSLVTTQRKLKAMSLLSGRNQLARAV
LNPNPMDFCTKDLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPG
TGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKE
KCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQEMHRRKEF
LDHQLDELSRQRALCRGGREIQRQELDEKIAKVSKERQELASKIKEVQGRPQKTQSIIIL
ESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVG
DPKQLPPTVISMKAQEYGYDQSMMARFYKLLEDNVEHNMIGRLPILQLTVQYRMHPDICL
FPSNYVYNRSLKTNRQTETNRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEI
IKLIKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDKKGPAEVDTVDGFQGRQKDCVI
VTCVRANTMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGA
IIKTCDKNYRHDAAKILKLKPVLQRSLTHPPAVAPEASRPQGGLPSNKLDSEFAKTSFTS
SLYHTPPDSKESSGTVTTKDPERPLVQDRLRDPRLLRRMGLDPEAKGMCLRDPQPLSPQH
PGATPPSGEPGFPASHQDLGGAQQSAARGTALNNHEPHAQCEPPAAGTGVSTSKSRCDWE
GGLSHRRETRAFSEGDRGRWSPESHYSKRSPGWDRTGPQKEGCSSKRRRLLW
NT seq
8079 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacaccaggtggcatttccaccgttgacttcctacagcgc
tatgcatccgagacccactccagtgagtttcaaacagctgatgaagacctctgctactgc
ttagagtgtgtggccgaataccacaaagcaagggatgatttaccattcttgcatgaggtt
ttatgggaattagaaaccttacgtctcataaattactttgaaaaatccatgaaggcagaa
attggagatgatgatgaattgtatatagtagacaacaacggagaggcacaactgtttgac
tttaccggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttatctgcttttacatgagcgtgttaatgaattatgtgttgaagcactttgtcggatg
gaacaagctaattgctcctttcaggtttttgacaaacatccaggcatctatttgtttctg
gtccatcccaatgaaatggttcggcgttgggctatcctgaccgcaagaaatttgggaaaa
gtggacagagatgattattatgacttgcaggaggttttgacttgcctttttaaagtcatt
gaattggggcttttggaaagtccagacatttatacttcttctgttctcgagaagggtaaa
ctgattcttctgccctcacacatgtacgataccaccaactacaaaaactattggttaggt
atttgcatgttgctgaccattctggaggagcaggccatggactcactattgctgggctca
gacaaacagaatgattttatgcaatcaatacttcacaccatggagaggcaagcagatgat
gatagtgtggatcctttttggccagccttacactgtttcatggtgattctggatcgcctt
ggatctaaggtctggggtcaacgtattgatcctattgaggcatttcagaccattatcaac
aatgtgagctacaataaagagatccaaaatatacggaacagctctgtaaggaccaagtta
gaaccggaatcatatttggatgatgcgacttgcagccagattgtatacaattataatccc
gaaaagaccaaaaaggattcagggtggagatcagccatttgcccagattattgtcctaac
atgtatgaagagatggaaacattagccagtgtgcttcagtcagatattggtcaagacatg
cgtgttcataacagcacctttctgtggttcatcccttttgttcagtccctcatggatctt
aaggatttgggtgtggcttatatagtagaggttattcatcatctgcactccgaagtcaag
gatgtcctcaaccaaacagatgccatgtgtgacaaagttactgaattttttcttctgatt
ttggtgtccgtgattgagctgcatagaaataaaaaatgtctgcatttgctgtgggttagt
tcccagcaatgggtagaagctgttgtaaaatgtgccaagctacctaccactgcatttgca
cggagttctgagaagtcatctggaaattgctctaaaggaacagcaatgatatcgtctctg
tcattgcattcaatgccatcaaattctgtacaactggcttgtgtgcagctgattagaagt
ctccttaaagaaggttatcagcttgggcagcaaactttatgtaagcgattctgggataaa
ctcaatttatttctgcgtggaaatttatctctaggttggcagttgactactcaggaaacc
catgagttacaaacttgtttaaagcaaattattaaaaacataaaagtcaaagtacctcaa
tgtaacacttttgtggatttgagtcctgcaggtaaaagctctccggcatcttacagtaaa
gaagaaagtgaacaaatagagaggagatccaataaagatctgcactgtctggaaaactcc
agcccaacattttctaaagaaccaatgaaagctgaggcatatcaaatacaagagaatata
ttgattaaagcaagcaacactatagaagaggataatgagcaaaattatatgaaagattgg
aaactagaagatcatctctcagccgagtcatgcataaagaagagtagtaaaaacgttttc
actgaaagagctcaagatcaagttaaaataagtacagggaagcagaagtccgtgaaagag
aattgtacttcaagaaatgtactgcagaattgtacttcaaggaatggtccagaaagggga
tatgacagaggaataataatgtcaacacgtttgttgaccgactctagcactgattctctg
gagaaggcatgcacatcaaatgaggatttatctttcaaggatgatgctcttggcaaaacc
gcaaaatcaaaaactaaggcacataaagatgaaatctgtgctaagttatcacatgtaata
aagaagcaacacaggaaaagtactttgatcaataatactggtaatttagaggaaaacgta
actgtgtctaacattgacagtttctattcaaggaaagattcaggaggtcagaaaggggat
ggcttcatgcacaatctctctttagaccctctcggcattctggatgaaaaaaatggggaa
caaaaatctcaaaagagtttattgctgaaaaagaaacaactgaagagtgaagagttagag
attttctcttcccatgaaaacagctatcaaatacaggaatgtcatgatgataaagatttg
gtctcatttacggaagtgaccaacactttcgtgaggaaaacgtctcccttcaaagatcct
gtgactgttcttgaatcaaaagataaggaaattagcaagaataccagtcagatgtcttct
cacttgagagaacaagctcctggcctcagtcctcagtctgacaccttaacagattctcag
atagacagagacctccacaagttatctttaatagctcaagccagcgttattaagttccca
tcagattcaactcaaaaaagctcatcccagctacaaaggagagtgaaagacgacagaaga
tgtttcccggctgaccagaataatactggggaagcctgtcggggccagattattattatt
tcagattctgatgatgatgatgatgatgatgaaggaattctaggtttggagaaacgtatt
aaacaagataaaataggcatcaagaaagaatgcccagagcagcatacttcaatagctagt
acgaatgtggaaaagagtttaataaaggaagaggagacaaagtcccttttgcagtttgag
gaatcagattctcagttttttgagtttgaaagtccatgtgaagtgttttcagtttggcaa
gatcaggaaccagacaagaattcagttcaagaaagtgaaaaaaactcttgttcgactgac
atagctgatatcacgaatgattggggttatgagacagattatgtatctgaagaggttatt
aagaaggtagcagagggcattgaaaaacacacagagccacagggtagtatttctgttggg
gaattctgtgaaattgaagtaaaaaaacgtaagagaaaacgatttgaaaaacctatggct
gaaggtcctctaaggccttcaccttctgatagaaatgaggaccagcctgatattcttaat
gagagaggtctgactgaaaatgattttaaaagtatggacctaaggacagtgagtcccact
tcaggtgttcagagagacaaagatactacggtttcactaaagaagtcttctccaaagctt
cgtacttactccaaacccattagaagagtcccactttctaaaactcctaagaaaacacat
tcagataccaagaaagggcagaacaaaagttcaaattatataagttgtaggacaactcct
gctatagttccaccaaagaaatttcgccagtgccctgaaccaactttaacagttgagaaa
cttggtctgaagaaggctcctcgtagggcatttgagttgtctcagcgatctctagagtgt
ttagttcggttacgccaccatggcaaaactgttggagtggttgatactagcaaaaagact
aagttaatttctcctcagactctctctgtcagaaacaataagaaactgctgacaagtcaa
gatcttcagttgcgaaggcagatgagacccaaatcacaacaaaatagacaaggacttttg
gattatgaaaataaagatactacaagagcagggctgtgtacagcacaaaattctgacata
cctgtcccagaatcagatggttcagattatagttacaaaggaggaactgaggtggttgct
aacagcactgggaaacaaacaaaatgtgtgtcttcggaaccagaacccatgaaaacaaaa
tatgtgtctcaggtgaccaatgatgcttgtcttttgaaccagtctgctgctgttgtattg
aatggaagaataccaacaaatgaaatcattgtctctgcttcggcagaccccttaggcggt
ggtgaccgaacagtacatcatttagagttggcaactttgaaagacggagagcctgaatcc
aacagtgatacagaagatgagaatatatttctaacacagcacgatcctgaagatatggat
ttgtgttcacagatggagaatggtaatgagaaactcattgaagtagttcatggcaaagat
acagctcaggtggaagaagattctgtaagtcagcctcagttggaatcttggaatagcaca
aaatgtaagtacaaagattgtgttgaaaccccaaaaaaccagggtgactactgctcaaaa
cactgtgaagctaaagcagcagatgaagatgtatttcgtaaacctggcttgcccctttct
gcatctaagccttccagaccttccactgcgaagatttttagctcaagtagtacttcacga
attgctaacctttccaagtctttggaaagtacctctgcacttccaccagctctaaaaaat
aagtcaaatggggcacaggctgttttgaaagtcccacagccagcctctctggtgtctcca
aagccagggggtgaagtgaagagtttgggcaatgtttttcatccccagactccaagtaat
tccagcaggcaaggttacaaactgacgtttggtgaaagcaaatccttctcggcttcctct
ccagtccacattctcttgtcatcacagtccatctctgacacttttgtcaaagaggtctta
aaatggaaatacgaaatgtttgtgaactttgatcagtgcgggcccccagcaagcctttgt
cagtccatctcgagacctgtgcctgtcagatttcaagattgtggagattattttaatgtt
tttttccctttgatggtattgaatacttttgaaacagtggcacaggagtggatcagctct
ccaaacaaagagaaattctatcagttgcatttacgaaaatttcctgctgattataaaaaa
tactgggagtttgtggttcatcttgaggaatgtgaactagctaaacaggttcatccaaag
gaaaatgatttggtgtttttggttcctgaaagacaaaatggagagaagaaagatacagag
agaaatcgcatgcaagatctccgtgaatatcattgtggttatattcataagtttcgccgc
acttcagtcatgcgcaatgggaaatctgagtgttccctttccatccagactcaagataat
ttaccagtcaatttaaatgaactcgtgaaatgcgttgtaatcagttctctggtaactaca
caaaggaagttgaaagccatgtctttgttgagtggacggaaccaactggccagagctgtt
ctgaatccaaaccccatggacttctgtacaaaagatttactaactacaacatctgagaga
attatcgcctacttaagagatttcaacgaagaccaaaagaaagcgatagaaactgcatat
gccatggtcaaacactccccgtcagttgccaagatctgtctgattcatggaccacctgga
acaggaaaatcaaaaactattgttggcctcctgtaccgcctactgacagagaaccagagg
aaggggcattcagatgaaaactccaatgccaaaatcaaacaaaaccgtgtccttgtgtgt
gcgccttccaacgcagctgttgatgaacttatgaaaaaaatcatcctcgaatttaaagaa
aaatgtaaagacaagaagaatcctttgggaaactgtggagatataaatttagtacgtctc
ggtccagaaaagtctattaataatgaggtcctaaaattcagtttggacagccaagttaac
cacagaatgaaaaaagacttaccttctcatgttcaggagatgcatagaagaaaggaattt
ctagatcaccaacttgatgaactttcccgccagcgtgctttatgccgaggtggaagggaa
atacagaggcaagaattagatgaaaaaattgcgaaagtttcaaaagagaggcaggaacta
gcttctaaaattaaagaggttcaaggacgcccacaaaaaacacagagcatcatcatctta
gagtctcatgtcatctgctgcacattgagcacgagtggtggtttactgcttgagtctgct
tttcgtgggcaagggggtgtccccttcagttgtgtcattgtcgatgaggccgggcagtct
tgtgaggttgagactcttactccactcatccatcgttgtaacaagctcatcctcgtagga
gatcctaaacagctccctcccacggtcatttctatgaaagcacaggaatatggctatgac
cagtcaatgatggcgcgcttctacaagctgctggaagacaacgtggagcacaatatgatc
ggcaggctgcctattttacagcttactgttcagtacaggatgcacccagacatatgtctc
ttcccctctaactatgtttataacagaagcttgaaaacaaatagacagactgaaaccaat
cggtgttcatcagactggccatttcaaccttacctggtgtttgatgtcggagacggctca
gaaagacgggataatgactcatatgtaaatgttcaagaaataaaactggtaatggaaata
attaaacttattaaagacaaaagaagggatgttactttccggaacattggcataataacc
cattacaaggctcagaagacgatgattcagaaggatttggacaaagaatttgataaaaaa
gggccagcggaagtagataccgtggatgggttccagggccggcagaaggattgcgttatt
gttacgtgcgtcagagcaaataccatgcagggctcaattggatttctggcaagtttgcag
agactgaacgtcaccatcacacgagccaagtacagcctcttcatcctcggacatttaagg
accctcatggaaaatcagcattggaaccacctgattcaggatgcacagaagcggggcgcc
atcatcaagacgtgcgacaagaactacaggcacgacgcagcgaagattctgaagctcaag
cccgtgctgcagagaagtctgactcacccgccagccgtagccccggaggcgtccagaccc
cagggcggcttgcccagcaacaagctcgacagtgaatttgccaagacatctttcacttct
tccctgtatcacacgccccctgactccaaggaatcttctggtactgtcactacaaaggac
cccgaaaggcctctcgttcaggaccggcttcgggacccacgactgctcaggaggatgggc
ctggaccccgaagccaaagggatgtgcctaagggatccgcagcccctgagcccgcagcac
cccggagcgacacctccctcgggcgagccaggcttccctgccagtcaccaggatctgggt
ggcgcacagcagtccgctgccagaggaacggctctgaacaaccacgaacctcacgcgcag
tgtgaacctccagctgctgggactggtgtctccacaagtaaaagcagatgtgactgggaa
ggagggctcagccacagaagagagacccgggctttcagtgagggcgaccggggcaggtgg
agcccggagagccactactcgaagaggagccccggctgggacaggacgggaccgcagaag
gagggctgcagctcaaagagaagaaggctcttatggtaa
DBGET
integrated database retrieval system
