KEGG   Zalophus californianus (California sea lion): 113937725
Entry
113937725         CDS       T07874                                 
Symbol
SRC
Name
(RefSeq) proto-oncogene tyrosine-protein kinase Src isoform X2
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
zca  Zalophus californianus (California sea lion)
Pathway
zca01521  EGFR tyrosine kinase inhibitor resistance
zca01522  Endocrine resistance
zca04012  ErbB signaling pathway
zca04015  Rap1 signaling pathway
zca04062  Chemokine signaling pathway
zca04081  Hormone signaling
zca04137  Mitophagy - animal
zca04144  Endocytosis
zca04360  Axon guidance
zca04370  VEGF signaling pathway
zca04510  Focal adhesion
zca04520  Adherens junction
zca04530  Tight junction
zca04540  Gap junction
zca04611  Platelet activation
zca04613  Neutrophil extracellular trap formation
zca04625  C-type lectin receptor signaling pathway
zca04727  GABAergic synapse
zca04750  Inflammatory mediator regulation of TRP channels
zca04810  Regulation of actin cytoskeleton
zca04912  GnRH signaling pathway
zca04915  Estrogen signaling pathway
zca04917  Prolactin signaling pathway
zca04919  Thyroid hormone signaling pathway
zca04921  Oxytocin signaling pathway
zca04926  Relaxin signaling pathway
zca05100  Bacterial invasion of epithelial cells
zca05135  Yersinia infection
zca05152  Tuberculosis
zca05161  Hepatitis B
zca05163  Human cytomegalovirus infection
zca05167  Kaposi sarcoma-associated herpesvirus infection
zca05168  Herpes simplex virus 1 infection
zca05203  Viral carcinogenesis
zca05205  Proteoglycans in cancer
zca05207  Chemical carcinogenesis - receptor activation
zca05208  Chemical carcinogenesis - reactive oxygen species
zca05219  Bladder cancer
zca05417  Lipid and atherosclerosis
zca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:zca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    113937725 (SRC)
   04015 Rap1 signaling pathway
    113937725 (SRC)
   04370 VEGF signaling pathway
    113937725 (SRC)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    113937725 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    113937725 (SRC)
   04137 Mitophagy - animal
    113937725 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    113937725 (SRC)
   04520 Adherens junction
    113937725 (SRC)
   04530 Tight junction
    113937725 (SRC)
   04540 Gap junction
    113937725 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    113937725 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    113937725 (SRC)
   04613 Neutrophil extracellular trap formation
    113937725 (SRC)
   04625 C-type lectin receptor signaling pathway
    113937725 (SRC)
   04062 Chemokine signaling pathway
    113937725 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    113937725 (SRC)
   04915 Estrogen signaling pathway
    113937725 (SRC)
   04917 Prolactin signaling pathway
    113937725 (SRC)
   04921 Oxytocin signaling pathway
    113937725 (SRC)
   04926 Relaxin signaling pathway
    113937725 (SRC)
   04919 Thyroid hormone signaling pathway
    113937725 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    113937725 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113937725 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    113937725 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    113937725 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    113937725 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    113937725 (SRC)
   05203 Viral carcinogenesis
    113937725 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    113937725 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    113937725 (SRC)
   05168 Herpes simplex virus 1 infection
    113937725 (SRC)
   05163 Human cytomegalovirus infection
    113937725 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    113937725 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    113937725 (SRC)
   05152 Tuberculosis
    113937725 (SRC)
   05100 Bacterial invasion of epithelial cells
    113937725 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    113937725 (SRC)
   05418 Fluid shear stress and atherosclerosis
    113937725 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    113937725 (SRC)
   01522 Endocrine resistance
    113937725 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:zca01001]
    113937725 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:zca04131]
    113937725 (SRC)
Enzymes [BR:zca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     113937725 (SRC)
Protein kinases [BR:zca01001]
 Non-receptor tyrosine kinases
  SRC family
   113937725 (SRC)
Membrane trafficking [BR:zca04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    113937725 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    113937725 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    113937725 (SRC)
  Macropinocytosis
   Kinases
    113937725 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 SH2_1 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 113937725
NCBI-ProteinID: XP_027478288
UniProt: A0A6J2FFL6
LinkDB
Position
8:118110162..118160032
AA seq 542 aa
MGSNKSKPKDASQRRRSLEPAENTHGGGGGAFPTSQTPSKPASADGHRGPSTAFPSAAAE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNSENPRGT
FLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYS
KHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTR
VAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLK
GETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLI
EDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREV
LDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGE
NL
NT seq 1629 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccaaggatgccagccaacggcgccgcagcctggagcct
gctgagaacacccacggtggcggcgggggtgccttccccacctcacagacacccagcaag
ccagcctccgctgatggccaccgaggccccagtacggccttcccctccgcagctgctgag
cccaagctgttcgggggcttcaactcctcagacacagtcacctccccgcagagggcgggg
ccgctggctggtggagtgaccacctttgtggccctctatgactatgagtctcggacagag
accgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagagagggtgactggtggctggcccactcgctcagcacgggacagacgggttac
atccccagcaactatgtggcgccctccgactctatccaggccgaggagtggtacttcggc
aagatcacaagacgggagtcagagcggttactgctcaattcggagaacccgagagggacc
tttctagtgcgagaaagcgagaccacgaaaggtgcctactgcctctccgtgtccgatttc
gacaacgccaagggcctcaacgtgaagcactacaagatccgcaagctggacagcggcggc
ttctatatcacctcccgcacccagttcagcagcctgcagcagctggtggcctactactcc
aaacatgctgacggcttgtgccaccgcctcaccactgtgtgccccacgtccaagccccag
actcagggcctggccaaggatgcttgggagatccctcgggagtccctgcggctggaggtc
aagctgggccagggctgtttcggagaggtgtggatggggacctggaatggaaccaccagg
gtggccatcaaaaccctgaagccaggcacaatgtctccggaggccttcctgcaggaggcc
caggtcatgaagaaactgaggcacgagaagctggtgcagctgtacgcagtggtgtctgag
gaacccatctacatcgtcacggagtacatgagcaaggggagtctgctggactttctcaag
ggggagacaggcaagtacctgcggctgcctcagctggtggacatggctgctcagatcgcc
tccggcatggcctacgtggaacggatgaactacgtccaccgggacctccgtgctgccaac
atcctggttggagagaacctcgtgtgcaaagtggctgactttgggctggctcggctcatc
gaagacaatgagtacacggcccggcaaggtgccaaattccccatcaagtggacggctcca
gaagcggccctctacggccggttcaccatcaagtcagatgtgtggtcctttgggatcctg
ctgacggagctcacgacaaagggacgggtgccctaccctgggatggtcaaccgtgaggtt
ttggaccaggtggagcgtggctaccggatgccctgcccgcccgagtgtcccgagtccctg
cacgacctcatgtgccagtgctggcggaaggagccagaggaacggcccaccttcgagtac
ctgcaggccttcctggaggactacttcacatccaccgagccccagtaccagcccggagag
aacctatag

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