Zalophus californianus (California sea lion): 113939180
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Entry
113939180 CDS
T07874
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca04140
Autophagy - animal
zca04141
Protein processing in endoplasmic reticulum
zca04210
Apoptosis
zca04932
Non-alcoholic fatty liver disease
zca05010
Alzheimer disease
zca05012
Parkinson disease
zca05014
Amyotrophic lateral sclerosis
zca05016
Huntington disease
zca05017
Spinocerebellar ataxia
zca05022
Pathways of neurodegeneration - multiple diseases
zca05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
113939180 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
113939180 (ERN1)
09143 Cell growth and death
04210 Apoptosis
113939180 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
113939180 (ERN1)
05012 Parkinson disease
113939180 (ERN1)
05014 Amyotrophic lateral sclerosis
113939180 (ERN1)
05016 Huntington disease
113939180 (ERN1)
05017 Spinocerebellar ataxia
113939180 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
113939180 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
113939180 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
113939180 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
zca01001
]
113939180 (ERN1)
Enzymes [BR:
zca01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
113939180 (ERN1)
Protein kinases [BR:
zca01001
]
Serine/threonine kinases: Other
IRE family
113939180 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
Motif
Other DBs
NCBI-GeneID:
113939180
NCBI-ProteinID:
XP_027480624
UniProt:
A0A6J2FL14
LinkDB
All DBs
Position
16:complement(47660111..47741805)
Genome browser
AA seq
975 aa
AA seq
DB search
MPARLLLALLALLLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVS
QDVEEKYEHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQF
QKELEKIQLLQQQLPFHPPGDMAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSTGS
ASKAGTSPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRTKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPAEVRETLGSLPDDFVRYFTSRFPYLLSHTYRAMEPCSHERLFQPYYF
HEPPEPRPPVTPDTL
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctactgctggcgctgctggcgctgctgctgctgcctggccccgggatt
tttggaagtcccagcacagtgacacttcctgaaaccttgttgtttgtgtcaactctggat
ggaagtttgcatgctgttagcaagaggacaggctcgatcaaatggactttaaaagaagat
ccggttctgcaggttccaacacatgtggaagagcctgccttcctcccagatcccaatgat
ggcagcctgtatacgcttgggggcaagaataatgaaggcctgacgaaacttccttttacc
atcccagagttggtacaggcatccccatgccgaagttcagacggaattctctacatgggt
aaaaagcaggacatttggtacgttatcgaccttctgaccggggagaagcagcagactctg
tcatcggcctttgcagacagcctctgcccatctacctctctgctttatctcgggcgaacg
gagtacaccatcaccatgtacgacaccaaaacccgtgagctccggtggaacgccacctac
tttgactatgcagcctctttgcctgaggacgacggggactataagatgtcccactttgtg
tccaacggcgacgggctggtggtgaccgtggacagtgaatccggcgacgtcctgtggatc
caaaactacgcttcccccgtggtggccttttatgtctggcagagggagggtctgaagaag
gtgatgcacatcaacgttgccgtggagaccctgcgctacctgaccttcatgtctggggag
gtgggccgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagcaag
ctgacgcccaccctgtatgttgggaaatactctaccagcctgtatgcctccccctccatg
gttcacgagggggtcgccgttgtgccccgaggcagcactcttcctttgctggaaggcccc
cagaccgacggggtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagac
ctcaagtttgaccctgggctcaaagggaagaacaagctcaactacctgaggaactactgg
cttctaattggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattc
cccaacaacctgcccaaacatcgggaaaacgtgattcctgccgattcagagaagaagagc
tttgaggaagttatcaacctggttgaccagacttcagaaaacgcgcctaccaccgtttca
caggatgtggaagagaaatacgagcatgcccctgccaagcccgaggcccccgtggactcc
atgctcaaggacattgccaccatcatcctgagcaccttcctgctcatcggctgggtggcc
ttcatcatcacctaccccttgagcatgcatcagcagcagcagctccagcaccagcagttc
cagaaggaactagagaaaatccagctcctgcaacagcagctgcccttccatccacctgga
gacatggctcaggatgctgagctcttggactcgtccggcctatactccgagagctcgggt
accagcagccccagcacgtcccccagagcctccaaccactcgctgcactccactggctcg
gcctccaaggctggcaccagccccttcctggagcaggacgatgaggatgaggaaaccagc
atggtgatagttgggaagatttcattctgtcccaaggacgtgctgggtcacggagctgag
ggtacgattgtgtaccggggcatgtttgacaaccgtgacgtggctgtcaagaggatcctc
cctgagtgtttcagtttcgcggaccgcgaagtccagctacttcgagaatcggatgagcac
cccaacgtgatccgttacttctgcacagagagggaccggcagttccagtacattgccatc
gagttgtgtgcggccaccctgcaggagtacgtggagcagaaggactttgcccacctcggc
ctggagcccatcaccttgctgcagcagaccacctcaggcctggcccatctccactccctc
aacattgttcatagagacctgaagccccacaacattctcctctccatgcccaacgcgcat
ggcaggaccaaggccatgatctcggacttcggcctctgcaagaagctggcggtaggccgg
cacagtttcagccgccgctcaggagtgccgggcacggaaggctggatcgctccagagatg
ttgagcgaagactgcaaggacaacccgacctacacagtggacatcttctctgcaggctgt
gtcttttactatgtgatctcggaaggcagccacccttttggcaagtccctgcagcggcag
gccaacatcctcctgggtgcctacagcctcgactgcttgcaccccgagaagcacgaagat
gtcattgcccgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccgtcc
gcgaagcacgtgctgaaacatccgttcttctggagcctggaaaagcagctgcagttcttt
caggacgtgagtgaccgaatagaaaaggagtccctggacggcccgatagtgaagcagctg
gagcgaggcgggagagctgtggtgaagatggattggagggagaacattaccgtccccctg
caaacagatctgcggaaattcagaacctataaaggtggctccgttcgagacctcctccga
gccatgagaaacaagaagcaccactaccgggagctccccgcggaggtacgggagacgctg
ggttccctccctgatgacttcgtgcgctacttcacgtcccgcttcccctacctcctctcc
cacacctaccgggccatggagccgtgcagccacgagcggctcttccagccctactacttc
cacgagcccccagagccccggcctccagtgactccagacaccctttga
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