Zalophus californianus (California sea lion): 113939562
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Entry
113939562 CDS
T07874
Symbol
NF1
Name
(RefSeq) LOW QUALITY PROTEIN: neurofibromin
KO
K08052
neurofibromin 1
Organism
zca
Zalophus californianus (California sea lion)
Pathway
zca01521
EGFR tyrosine kinase inhibitor resistance
zca04010
MAPK signaling pathway
zca04014
Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:
zca00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113939562 (NF1)
04014 Ras signaling pathway
113939562 (NF1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113939562 (NF1)
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Ortholog
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GFIT
Motif
Pfam:
PH_NF1
RasGAP
CRAL_TRIO_2
CRAL_TRIO
MIF4G_like_2
Motif
Other DBs
NCBI-GeneID:
113939562
NCBI-ProteinID:
XP_035580487
UniProt:
A0A6P9FHP3
LinkDB
All DBs
Position
16:19258049..19534433
Genome browser
AA seq
2841 aa
AA seq
DB search
MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT
ILKNVNNMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQGCGAHPAIRMAPSLTFKEKVTSLKFKEK
PTDLETRSYKYLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE
IAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL
REILICRNKFLLKNKQADRSSCHFLFLYGVGCDVSSSGTTGQMSMNHEELLPSCTPGASL
RKGKGNSSMDSAAGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD
IRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEHPTAGNTEAWE
DTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWI
NMTGFLCALGGVCLQQRSNSGLATYSPPMGPVSERKGSMISVMSSEGNADTPVSKFMDRL
LSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNT
QFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQL
VEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVS
LLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRL
ASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAE
TVLADRFERLVELVTMMGDQGELPIAMALANVVPCSQWDELARVLVTLFDSRHLLYQLLW
NMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVS
FEVDPTRLEQSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLN
KATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG
LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAARRFFLDIASDCPTSDAVNHSLSF
ISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTH
WSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQI
NGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVY
IYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLK
VFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQ
FTLTIANQGTPLTFMHQECEAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIA
LLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAAN
EPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKL
ITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVAL
ASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAA
HLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSL
PKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMR
DIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESC
LKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALL
EQNLHTLDSLRVFNDKSPEEVFMAIRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGY
RHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHR
KSLLLTDISMENVPMDTYPIHHGDPSYRTLKENQPWSSPKGSEGYLAATYPTVGQTSPRA
RKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYE
METQRISSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQRI
LYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQY
QTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLTP
TSPYPPAVQSQLSITANLNLSNSMTSLATSQHSPGIDKENVELSPTTGHCNSGRTRHGSA
SQVQKQRSAGSFKRNSIKKIV
NT seq
8526 nt
NT seq
+upstream
nt +downstream
nt
atggccgcgcacaggccggtggaatgggtccaggccgtggtcagccgcttcgacgagcag
cttccaataaaaacaggacagcagaacacacataccaaagtcagtaccgaacacaacaag
gaatgtcttattaatatttccaaatacaagttttctttggttatcagcggcctcaccact
atcttaaagaatgttaacaatatgagaatatttggagaagctgctgaaaaaaatttatat
ctctctcagttgattatattggatacactggaaaaatgtcttgctgggcaaccaaaggac
acaatgagattagatgaaacaatgctggtcaaacagttgctcccagaaatctgccatttt
cttcatacctgtcgggaaggaaaccagcatgccgctgaacttcggaattctgcctctggt
gttttattttctctcagctgcaacaacttcaatgcagtgtttagtcggatttctaccaga
ttacaggaattgactgtttgttcagaagacaatgttgatgttcatgatatagaattgtta
cagtatatcaatgtggattgtgcaaaattaaaacgactcctaaaggaaactgcatttaaa
tttaaagccctaaagaaggttgcacagttagcagttataaatagcctggaaaaagcattt
tggaactgggtagaaaattatccagatgaatttacaaagctataccagattccacagact
gatatggctgaatgtgcagaaaaactgtttgacttggtggatggttttgctgaaagcacc
aaacgtaaagcagcagtttggccactacaaatcattctccttatcttgtgtccagaaata
atccaggatatctccaaggatgtggttgatgaaaacaacatgaataagaagttgtttttg
gacagtctacgaaaagcacttgccggccacggaggaagcaggcagctgacggaaagtgcc
gcaattgcctgtgtcaaactgtgtaaagcaagtacttacatcaactgggaagataactct
gtcattttcctactagttcagtccatggtggtagatcttaagaacctgctttttaatcca
agtaaaccattctcaagaggcagtcagcctgcagatgtggatctaatgattgactgcctt
gtttcttgctttcgtataagccctcacaacaaccaacactttaagatctgcctggctcag
aattccccttctacatttcactatgtgctggtaaattcactccatcgaatcatcaccaat
tctgcattggattggtggcctaagattgatgctgtatactgtcactcagttgagcttcga
aacatgtttggtgaaacccttcataaagcagtgcagggctgtggagcacacccagcaata
cggatggcacctagtcttacatttaaagaaaaagtaacaagccttaaatttaaagaaaaa
cctacagacctggagacaagaagctataagtatcttctcttgtccatggtgaaactaatt
catgcagatccaaagctcttgctttgtaatccaagaaaacaggggcctgaaacccaaggc
agtacagcggagttaataacagggctcgtccagctggtccctcagtcacacatgccagag
attgctcaggaagcaatggaggctctgctggttcttcatcagttagatagcattgatttg
tggaatcctgatgctcctgtagaaacattctgggaaattagctctcaaatgcttttttac
atctgcaagaaattaactagccatcaaatgcttagtagcacagaaattctcaaatggttg
cgggaaattttgatctgcaggaataaatttcttcttaaaaataagcaggcagatagaagt
tcctgtcactttctcttcctttatggggtaggatgtgatgtttcttcaagtggaactacc
ggtcagatgtccatgaatcatgaagaattactaccttcttgtactcctggagcctctctt
cggaagggaaaaggaaactcatccatggatagtgcagcagggtgcagtggcaccccgccg
atctgccgacaagctcagactaaactagaagtggccctgtatatgttcctgtggagccct
gacactgaagctgttctggtggccatgtcctgtttccgccacctctgcgaggaagcagat
atccggtgtggggtagatgaggtgtcagtgcacaacttcttgcccaactataacacattt
atggaatttgcctctgtcagcaatatgatgtcaacaggaagagcagcacttcagaaaaga
gtgatggcactactaaggcgcattgagcatcccactgcaggaaacaccgaggcttgggaa
gatacacatgcaaagtgggaacaagctacaaaactaatcctcaactacccgaaagctaaa
atggaagatggccaggctgctgaaagccttcacaagaccattgttaagaggcgaatgtct
catgtgagtggaggaggatccatagatttgtctgacacggactccctacaggaatggatc
aacatgactggcttcctttgtgcccttgggggagtgtgcctacagcagagaagcaattct
ggcctggcaacctatagcccacccatgggcccagtcagtgaacgcaagggttccatgatt
tcagtgatgtcttcagagggaaatgcagatacacctgtcagcaaatttatggatcggctg
ttatccttaatggtgtgtaaccatgagaaagtgggacttcaaatacggaccaatgttaag
gatctggtgggtcttgaattgagtcctgctctttatccaatgctgtttaacaaattaaag
aataccatcagcaagttttttgactcccaaggacaggttttattgactgacaccaatact
caatttgtggagcaaaccatagctataatgaagaacttactagataatcatactgaaggc
agctcggaacatctggggcaagctagcattgaaacaatgatgttaaatctagtcagatat
gttcgtgtgcttgggaatatggtccatgcaattcaaataaaaacgaaactgtgtcagtta
gtcgaggtaatgatggcaagaagagatgacctctcattttgtcaagagatgaagtttagg
aataagatggtagaatacctgacagactgggtgatgggaacatcaaaccaagcagcagat
gatgatgtaaaatgtcttacaagagacttggaccaggcgagcatggaagcagtagtttca
ctcctggctggtcttccgctgcagccggaggaaggagatggtgtggaattgatggaagcc
aaatcacagttatttcttaagtatttcacattgttcatgaaccttttgaatgactgtagt
gaagttgaagatgaaaatgcacaaacaggtggcaggaaacgtggcatgtctcggaggctg
gcgtcactgagacactgtacggtcctcgcaatgtcaaacttactgaatgctaatgtggac
agtggcctcatgcactccataggtttaggttatcacaaagatcttcagacaagagctaca
tttatggaagttctgacaaaaatcctccagcaaggcacagaatttgacacacttgcagaa
acggtgctggccgaccggtttgagaggctggtagaattggtcacgatgatgggagaccag
ggggagctcccgatagccatggcgctggccaacgtggtcccgtgttctcagtgggatgaa
ctagctcgagttctagtgactctgtttgattctcggcatttactctaccaactgctctgg
aacatgttttctaaggaagtagaattggcagactccatgcagactcttttccgaggaaac
agcttagccagtaaaataatgaccttctgtttcaaggtatatggtgctacctacctacaa
aaactcctggatccgttattacgaattgtgatcacatcctctgattggcagcatgttagc
tttgaagtggatcctaccaggttagagcagtcagagagtcttgaggaaaaccaacggaac
cttcttcagatgactgaaaagttcttccatgccatcatcagttcctcctcagaattcccc
cctcagcttagaagtgtgtgccactgtttataccaggcaacttgccactccctactgaat
aaagctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccagcgattccct
cagaacagcatcggtgcagtgggaagtgccatgttcctcagatttatcaatcctgccatt
gtctcaccatatgaagcagggattttagataaaaagccaccacctagaatcgaaaggggc
ttgaagttaatgtcaaagatactgcagagtattgccaatcatgttcttttcacaaaagaa
gagcatatgcggccttttaatgattttgtgaaaagcaactttgatgcagcacggaggttt
ttccttgatatagcatctgattgtcctacaagtgatgcagtaaatcatagtctttccttc
atcagtgatggcaatgtgcttgctttacatcgtctgctctggaacaatcaagagaaaatt
ggccagtatctttctagcaacagggatcacaaagctgttggaagacgacctttcgataag
atggcaacacttcttgcgtacctgggtcctccagagcataaacctgtggcagatacacac
tggtccagccttaaccttaccagttcaaagtttgaggaatttatgactaggcatcaagta
catgaaaaagaagaattcaaggctttgaaaacattaagcattttctaccaagctgggact
tccaaagctgggaatcctatattttattatgttgcacggaggtttaaaactggtcaaatc
aatggtgatttgctgatataccacgtcttgctgactttaaagccatattatgcaaagcca
tatgaaattgtagtggaccttacccatactgggcctagcaatcgctttaaaacggacttt
ctctccaagtggtttgttgtttttcctggctttgcttatgacaatgtctctgcagtctat
atctacaactgtaactcctgggtcagggagtataccaagtatcatgagcggctgctgact
ggcctcaaaggcagcaaaaggctcatcttcatagactgtcctgggaaactggctgagcac
atagagcatgaacagcagaaactgcctgctgccacgctggctttagaagaggacttgaag
gtattccacaatgctctcaagctagctcacaaagacaccaaggtttctattaaggttggt
tctactgctgtccaggtaacctcagcagagcggacaaaagtgttggggcaatcagtcttt
ctaaatgatatctattatgcttcggaaattgaagagatatgcctggtggatgagaaccag
ttcaccttgaccattgcaaaccagggcacaccactcaccttcatgcaccaggagtgcgaa
gccattgtccagtctatcattcatattcggacacgctgggagctgtcgcagcctgactcc
atcccccagcacaccaagattcggccaaaagatgtccctgggacgctgctcaatattgca
ttacttaatttaggcagttcagaccctagtttacggtcagccgcctataatcttctgtgt
gccttaacttgtacctttaatttaaaaatcgagggccagttactagagacatcaggttta
tgcatccctgccaacaacaccctctttattgtctctattagtaagacactggcagccaat
gagccacatctcaccttagaatttttggaagagtgtatttctggatttagcaaatctagt
attgaattgaaacacctttgtttggaatacatgactccatggctgtcaaatctagtccgt
ttttgtaaacacaatgatgatgccaaacgacaaagagttactgctattcttgataagctg
ataacaatgaccataaatgaaaaacagatgtacccatctatccaagccaaaatatggggg
agccttgggcagattacagatctccttgatgttgtactagacagtttcatcaaaaccagt
gcaacaggtggcctgggatcaataaaagctgaggtgatggcagatactgctgtagctttg
gcttctggaaatgtgaaattggtttcaagcaaggttattggaaggatgtgcaaaataatt
gacaagacatgcttatctccaactcctaccttagaacaacatcttatgtgggacgatatt
gctattctagcacgctacatgctgatgctgtccttcaacaattcccttgacgtggcagct
catctcccctacctcttccacgttgttactttcttagtagccacagggccgctctccctt
agagcttccacccatggattggtcattaatatcattcactctctgtgtacttgttcacag
cttcattttagtgaagagaccaagcaagttttgagactcagtttgacggagttctcatta
cccaagttttacctgctgtttggcattagcaaagtcaagtcagctgccgtcattgccttc
cgctctagttaccgggacaggtcattctctcccggctcctatgaaagggagacttttgct
ttgacttccctggaaacagtcacagaagctttgttggagatcatggaggcatgtatgaga
gatattccaacatgcaagtggctggaccagtggacagaactagctcaaagatttgcattc
cagtataatccatcactgcaaccaagagctcttgttgtctttggctgtattagcaaacgt
gtgtctcatgggcagataaagcagattatccgtattcttagcaaggcacttgagagttgc
ttaaaaggacctgatacttacaacagtcaagttctgatagaagccacagtaatagcacta
accaagttacaaccacttcttaataaggactcccctctgcacaaagccctcttttgggtc
gctgtggctgtgctacagctcgacgaggtcaacttgtattcagcaggcaccgcacttctg
gaacagaacctgcacaccttagacagtctgcgggtattcaacgacaagagtccagaggaa
gtatttatggcaatccggaatcctcttgaatggcactgcaagcaaatggatcattttgtt
ggactcaatttcaactctaactttaacttcgcactggttggacacctcttaaaagggtac
agacatccttcacctgccattgttgcaagaacagtcagaattttgcatacactactaact
ctggttaacaaacatagaaactgtgataaatttgaggtgaacacacagagcgtggcttac
ttagcagccttactcacagtgtctgaggaggttcgaagtcgctgtagcctaaaacataga
aagtctcttcttcttactgatatttcaatggaaaatgttcctatggatacatatcccatt
catcatggcgaccctagctataggacactaaaggagaaccagccgtggtcatctcccaaa
ggttctgaagggtaccttgcggccacctatccaactgtgggccagaccagtccccgagcc
aggaaatccatgagtctggacatggggcagccttctcaggccaatacgaagaagttgctg
ggaacaaggaaaagttttgatcacttgatatcagacacaaaggctcctaaaaggcaagaa
atggaatcagggatcacaacaccccccaaaatgaggagagtagcagaaactgattatgaa
atggaaactcagaggatttcctcatcacaacaacacccgcatttacgcaaagtttcagtg
tctgaatcaaatgttctcttggatgaagaagtacttactgatccgaagatccaagcactt
cttcttactgttctggctacgctggtaaaatacaccacagacgagtttgatcagcgaatt
ctttatgagtacttagcagaagccagtgttgttttccccaaggtttttcctgtcgtgcac
aatttgttggactctaagatcaataccctgttgtcattgtgccaagatccaaatttgtta
aatccaattcatggaatcgtgcagagtgtggtgtaccatgaggaatccccaccacagtac
caaacatcttacctacaaagttttggttttaatggcttgtggcggtttgcaggacccttt
tcaaagcaaacacaaatcccagactatgctgagcttattgttaagtttcttgatgccttg
attgacacgtatttgcctggaattgatgaagaaaccagtgaggagtccctcctgacaccc
acttctccttatcctcctgcagtgcagagccagcttagtattactgctaaccttaacctt
tctaattccatgacctcacttgcaacttcccagcattccccaggaatcgacaaggagaac
gttgaactctcccccaccaccgggcactgtaacagtggacgaactcgccatggatccgca
agccaagtgcagaagcaaagaagcgctggcagtttcaaacgtaatagcattaagaagatc
gtgtga
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integrated database retrieval system
