Zootoca vivipara (common lizard): 118082364
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Entry
118082364 CDS
T07275
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
zvi
Zootoca vivipara (common lizard)
Pathway
zvi00270
Cysteine and methionine metabolism
zvi00480
Glutathione metabolism
zvi01100
Metabolic pathways
zvi01240
Biosynthesis of cofactors
zvi04216
Ferroptosis
Module
zvi_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
zvi00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
118082364 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
118082364 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
118082364 (GCLC)
Enzymes [BR:
zvi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
118082364 (GCLC)
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Motif
Pfam:
GCS
Motif
Other DBs
NCBI-GeneID:
118082364
NCBI-ProteinID:
XP_034965681
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Position
LG3:87612583..87641773
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AA seq
634 aa
AA seq
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MGLLSQGSPLSWEKTQRHAEHVRKHGILQFLHIYRAVGERHKDVLKWGDEVEYMLVVFDH
KNKRAQLSLTGGDVLHTLQEKGERANPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRLEAASVLKQNEAVCTVTSFPRLGCPGFTIPECVPTPVETGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEGARAVKPGHVYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAAAPFYRGYVTDIDCRWGV
ISASVDDRTREERGLEPLKNNRYRINKSRYDSIDSYLSECGEKYNDIDLTVDKEIYEQLV
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVVDGCGPAQNGTETDSEEYTLMSIDTIINGKEGVFPGLIPVLN
SYLENMEVDVDTRCSILNYLKLIKKRASGELMTAARWMREFVANHPAYKHDSVITEEINY
SLIWKCYQIAEEQVECPELLGNKVKYSGTKSGTF
NT seq
1905 nt
NT seq
+upstream
nt +downstream
nt
atggggctcctgtcgcagggctccccgctgagctgggagaagacgcagcgccacgcggag
cacgtgcgcaaacacggcatcctccagttcctgcacatctaccgggcggtgggcgagagg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgctggtagtatttgaccat
aaaaacaagagggcgcagttgtccctaactggaggagacgttcttcatactttgcaagag
aaaggggaaagagcaaacccaaaccatccaactctgtggaggccagaatatggaagctat
atgattgaggggacccctgggcaaccctatggagggacaatgtccgaatttaacactgtg
caagacaacatgagaaagcgacgcctggaggctgcttctgtgctgaaacaaaacgaagct
gtttgcactgtgacatcatttccaagattgggctgtccaggatttacgataccggagtgt
gtgcctaccccagttgagacaggagcctccaagtctctcttcttcccggacgaagccatt
aacaaacatcccaggtttagtactttaacgagaaacattcgacacagaagaggagaaaaa
gtagtgataaacgtaccaatatttaaagacaagaatactccatcgccgttcatagaaaca
ttccctaatgatgatggtgagggagcaagagcagtcaagcctggccatgtctacatggat
gccatggggtttggaatgggcaactgctgccttcaggtaacattccaggcttgcagcatc
tctgaagcaagatacctttatgatcagctagcaaccatctgtcccattgtgatggcttta
agtgcggcagctccattctacagaggctacgtgacagatatcgattgccgttggggagtc
atatctgcctccgtagacgacagaacgagggaggagaggggattggagccattgaagaac
aaccgctacagaatcaataaatccagatacgattccatagacagttatctctctgaatgt
ggtgaaaaatacaatgacattgatttgacggtagataaagaaatctacgagcagttagta
aaggaaggcattgaccatctgttggcccaacacattgctcatttatttatccgtgatcct
ttgactctgttcgaagagaaaatacatctggatgatgcaaatgaatctgaccactttgag
aatattcagtcaacaaactggcagacaatgagattcaaaccaccacctccgaattcagac
attggatggagggttgagttcagaccaatggaggtccagttaacagacttcgaaaattcc
gcctatgttgtctttgtagtgttgctgactcgagtcattctctcctacaaactggatttt
ctcattcctttgtccaaggtggatgagaacatgaaagtagctcagaaacgggatgctgtt
cggcaaggcatgttttatttcagaaaagacatttgtaaaggtggcaatgctgtagtggac
ggatgtgggccagctcaaaatggtacagagacagattctgaagagtataccttaatgagc
atagatacaataatcaatggaaaggaaggagtatttcctggattaattccagttttgaac
tcttaccttgaaaacatggaagtggatgtagatacaaggtgcagcattctaaactatctg
aaactcattaaaaagagagcatcaggagaattaatgacagccgctcgatggatgcgagag
tttgtcgcaaaccacccagcatacaaacacgacagtgtgattaccgaagagattaattac
agcctgatttggaaatgctaccaaattgccgaagagcaagttgaatgccctgaactactt
ggtaacaaagtaaaatacagcggaactaaaagcggcactttttga
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