+C	Peptidoglycan biosynthesis and degradation proteins	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidoglycan Biosynthesis and Degradation Proteins - Aggregatibacter actinomycetemcomitans D7S-1</h2>
%<!-- w=600, -->
!
A<b>Precursor biosynthesis</b>
B  Transferase/Dehydrogenase
C    D7S_02021 UDP-N-acetylglucosamine 1-carboxyvinyltransferase	K00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7] 
C    D7S_01317 murB; UDP-N-acetylenolpyruvoylglucosamine reductase	K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98] 
B  Amino acid ligase
C    D7S_01482 murC; UDP-N-acetylmuramate--alanine ligase	K01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8] 
C    D7S_01479 murD; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase	K01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9] 
C    D7S_01476 murE; UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase	K01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13] 
C    D7S_03235 D-alanine--D-alanine ligase	K01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4] 
B  Racemase
C    D7S_02382 alr; alanine racemase	K01775 alr; alanine racemase [EC:5.1.1.1] 
C    D7S_01780 glutamate racemase	K01776 murI; glutamate racemase [EC:5.1.1.3] 
B  Carboxypeptidase
B  Glycosyltransferase
C    D7S_01478 phospho-N-acetylmuramoyl-pentapeptide-transferase	K01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13] 
C    D7S_01481 UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-UDP acetylglucosamine transferase	K02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227] 
B  Diphosphatase
B  Flippase
C    D7S_01850 multidrug transporter MurJ	K03980 murJ; putative peptidoglycan lipid II flippase 
#
A<b>Peptidoglycan biosynthesis and degradation</b>
B  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
C    D7S_01096 penicillin-binding protein	K05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4] 
C    D7S_00377 mrcB; bifunctional glycosyl transferase/transpeptidase	K05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4] 
C    D7S_02090 penicillin-binding protein	K05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28] 
B  DD-Transpeptidase (Class B PBP)
C    D7S_01194 penicillin-binding protein 2	K05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4] 
C    D7S_01475 peptidoglycan synthase	K03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4] 
B  DD-Carboxypeptidase/DD-Endopeptidase (Low molecular weight PBP)
C    D7S_01197 D-alanyl-D-alanine carboxypeptidase	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
C    D7S_02221 D-alanyl-D-alanine carboxypeptidase	K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] 
C    D7S_00073 D-alanyl-D-alanine endopeptidase	K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-] 
B  Glycosyltransferase
C    D7S_01520 peptidoglycan transglycosylase	K03814 mtgA; monofunctional glycosyltransferase [EC:2.4.99.28] 
B  Transpeptidase
C    D7S_02154 L,D-transpeptidase	K21470 ycbB; L,D-transpeptidase YcbB 
B  Carboxypeptidase
B  Endopeptidase
C    D7S_00157 mepA; murein endopeptidase	K07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-] 
C    D7S_02238 lipoprotein	K13694 mepS; murein DD-endopeptidase / murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13] 
C    D7S_00212 peptidase M23	K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-] 
B  Sortase
B  Lytic transglycosylase
C    D7S_01522 septation protein A	K08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
C    D7S_02043 murein transglycosylase	K08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29] 
C    D7S_02200 lytic transglycosylase	K08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29] 
C    D7S_01044 mltC; murein transglycosylase	K08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29] 
C    D7S_01913 murein transglycosylase	K18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29] 
C    D7S_01617 aminodeoxychorismate lyase	K07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29] 
C    D7S_01196 RlpA	K03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29] 
B  Amidase
C    D7S_02275 N-acetylmuramoyl-L-alanine amidase	K01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] 
C    D7S_01724 N-acetyl-anhydromuranmyl-L-alanine amidase	K03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28] 
B  Structural protein
!
#<hr>
#[ <a href="/kegg/brite.html">BRITE</a> | <a href="/kegg/kegg2.html">KEGG2</a> | <a href="/kegg/">KEGG</a> ]<br>
#Last updated: January 30, 2024