+C	Peptidases and inhibitors	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Peptidases and Inhibitors - Azospirillum brasilense Az39</h2>
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A<b>Aspartic peptidases</b>
B  Family A1: pepsin family
B  Family A2: retropepsin family
B  Family A5: thermopsin family
B  Family A8: signal peptidase II family
C    ABAZ39_10510 peptidase A8	K03101 lspA; signal peptidase II [EC:3.4.23.36] 
C    ABAZ39_28655 signal peptidase II	K03101 lspA; signal peptidase II [EC:3.4.23.36] 
B  Family A22: presenilin family
B  Family A24: type IV prepilin peptidase family
C    ABAZ39_26220 hypothetical protein	K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] 
C    ABAZ39_32150 hypothetical protein	K02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43] 
B  Family A25: gpr protease family
B  Family A26: omptin family
B  Family A28
B  Family A31: HybD endopeptidase family
C    ABAZ39_22045 hybD; hydrogenase 2 maturation endopeptidase	K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-] 
C    ABAZ39_23405 hycI; hydrogenase 3 maturation protease	K08315 hycI; hydrogenase 3 maturation protease [EC:3.4.23.51] 
B  Family A36
#
A<b>Cysteine peptidases</b>
B  Family C1: papain family
B  Family C2: calpain family
B  Family C3: picornain family
B  Family C4: NIa protease family
B  Family C5
B  Family C9
B  Family C10: streptopain family
B  Family C11: clostripain family
B  Family C12: ubiquitin C-terminal hydrolase family
B  Family C13: legumain family
B  Family C14: caspase family
B  Family C15: pyroglutamyl peptidase I family
C    ABAZ39_13800 pyrrolidone-carboxylate peptidase	K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3] 
B  Family C16
B  Family C19: ubiquitin-specific protease family
B  Family C25: gingipain family
B  Family C26: gamma-glutamyl hydrolase family
C    ABAZ39_06420 glutamine amidotransferase	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] 
C    ABAZ39_18790 guaA; GMP synthase	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] 
C    ABAZ39_22775 glutamine amidotransferase	K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] 
C    ABAZ39_12930 glutamine amidotransferase	K07010 K07010; putative glutamine amidotransferase 
C    ABAZ39_13860 peptidase C26	K07010 K07010; putative glutamine amidotransferase 
B  Family C27
B  Family C30
B  Family C37
B  Family C39
B  Family C40
B  Family C44
C    ABAZ39_06215 amidophosphoribosyltransferase	K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] 
C    ABAZ39_15580 glutamate synthase	K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] 
C    ABAZ39_05550 glucosamine--fructose-6-phosphate aminotransferase	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] 
C    ABAZ39_24045 iron dicitrate transport regulator FecR	K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] 
C    ABAZ39_04840 asparagine synthase	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] 
C    ABAZ39_20710 asparagine synthase	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] 
C    ABAZ39_24875 asparagine synthase	K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] 
B  Family C45
B  Family C46: hedgehog family
B  Family C47: staphopain family
B  Family C48: Ulp1 endopeptidase family
B  Family C50: separase family
B  Family C54: Aut2 peptidase family
B  Family C55: YopJ protease family
B  Family C56: PfpI endopeptidase family
C    ABAZ39_07490 glutamine amidotransferase	K05520 yhbO; deglycase [EC:3.5.1.124] 
C    ABAZ39_13465 peptidase C56	K05520 yhbO; deglycase [EC:3.5.1.124] 
C    ABAZ39_03600 AraC family transcriptional regulator	K18199 inhA; cyclohexyl-isocyanide hydratase [EC:4.2.1.103] 
B  Family C57: vaccinia virus I7 peptidase family
B  Family C58
B  Family C59
B  Family C60
B  Family C63
B  Family C64
B  Family C65
B  Family C67
B  Family C69
B  Family C70
B  Family C75
B  Family C76
B  Family C78
B  Family C79
B  Family C82
C    ABAZ39_20055 hypothetical protein	K16291 erfK; L,D-transpeptidase ErfK/SrfK 
C    ABAZ39_03060 peptidoglycan-binding protein	K21470 ycbB; L,D-transpeptidase YcbB 
C    ABAZ39_22470 hypothetical protein	K21470 ycbB; L,D-transpeptidase YcbB 
B  Family C83
B  Family C85
B  Family C86
B  Family C88
B  Family C89
B  Family C97
B  Family C98
B  Family C110
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A<b>Glutamic peptidases</b>
B  Family G1
B  Family G4
B  Family G5: prenyl protease 2 family
C    ABAZ39_26025 hypothetical protein	K07052 K07052; CAAX protease family protein 
#
A<b>Metallo peptidases</b>
B  Family M1
C    ABAZ39_17055 pepN; aminopeptidase N	K01256 pepN; aminopeptidase N [EC:3.4.11.2] 
B  Family M2
B  Family M3
C    ABAZ39_23265 peptidase M3	K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5] 
C    ABAZ39_09225 oligoendopeptidase F	K08602 pepF; oligoendopeptidase F [EC:3.4.24.-] 
B  Family M4: thermolysin family
B  Family M5: mycolysin family
B  Family M6: immune inhibitor A family
B  Family M7: snapalysin family
B  Family M8: leishmanolysin family
B  Family M9
B  Family M10
C    ABAZ39_22420 hypothetical protein	K01406 prtC; serralysin [EC:3.4.24.40] 
C    ABAZ39_24920 hypothetical protein	K01406 prtC; serralysin [EC:3.4.24.40] 
C    ABAZ39_32865 hypothetical protein	K01406 prtC; serralysin [EC:3.4.24.40] 
C    ABAZ39_33325 hypothetical protein	K01406 prtC; serralysin [EC:3.4.24.40] 
B  Family M12: astacin/adamalysin family
B  Family M13: neprilysin family
B  Family M14: carboxypeptidase A family
B  Family M15: zinc D-Ala-D-Ala carboxypeptidase family
C    ABAZ39_14355 D-alanyl-D-alanine dipeptidase	K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22] 
B  Family M16: pitrilysin family
C    ABAZ39_10520 zinc protease	K07263 pqqL; zinc protease [EC:3.4.24.-] 
C    ABAZ39_10525 zinc protease	K07263 pqqL; zinc protease [EC:3.4.24.-] 
B  Family M17: leucyl aminopeptidase family
C    ABAZ39_19705 aminopeptidase A	K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] 
B  Family M18
B  Family M19: membrane dipeptidase family
C    ABAZ39_29495 peptidase M19	K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] 
B  Family M20
C    ABAZ39_01565 succinyl-diaminopimelate desuccinylase	K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] 
C    ABAZ39_15670 succinyl-diaminopimelate desuccinylase	K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] 
C    ABAZ39_15755 allantoate amidohydrolase	K02083 allC; allantoate deiminase [EC:3.5.3.9] 
B  Family M23
B  Family M24
C    ABAZ39_06230 methionine aminopeptidase	K01265 map; methionyl aminopeptidase [EC:3.4.11.18] 
C    ABAZ39_11115 methionine aminopeptidase	K01265 map; methionyl aminopeptidase [EC:3.4.11.18] 
C    ABAZ39_02700 X-Pro aminopeptidase	K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] 
B  Family M26
B  Family M27
B  Family M28: aminopeptidase Y family
B  Family M29: aminopeptidase T family
B  Family M32: carboxypeptidase Taq family
C    ABAZ39_04555 peptidase M32	K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19] 
B  Family M34: anthrax lethal factor family
B  Family M35: deuterolysin family
B  Family M36: fungalysin family
B  Family M38: beta-aspartyl dipeptidase family
B  Family M41: FtsH endopeptidase family
C    ABAZ39_04940 cell division protein FtsH	K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] 
C    ABAZ39_07990 cell division protein FtsH	K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] 
B  Family M42: glutamyl aminopeptidase family
B  Family M43: cytophagalysin family
B  Family M44
B  Family M48: Ste24 endopeptidase family
C    ABAZ39_12780 heat shock protein HtpX	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] 
C    ABAZ39_17845 peptidase M48	K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] 
B  Family M49: dipeptidyl-peptidase III family
B  Family M50: S2P protease family
C    ABAZ39_08200 zinc metalloprotease	K11749 rseP; regulator of sigma E protease [EC:3.4.24.-] 
C    ABAZ39_25160 peptidase	K16922 yydH; putative peptide zinc metalloprotease protein 
B  Family M54
B  Family M55: DppA aminopeptidase family
B  Family M56
B  Family M67
B  Family M72
B  Family M73
B  Family M74
C    ABAZ39_09875 peptidase	K07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-] 
C    ABAZ39_14860 hypothetical protein	K07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-] 
B  Family M80
B  Family M82
B  Family M85
B  Family M88
B  Family M90
B  Family M98
#
A<b>Asparagine peptide lyases</b>
B  Family N1
B  Family N8
#
A<b>Mixed peptidases</b>
B  Family P1: DmpA aminopeptidase family
B  Family P2
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A<b>Serine peptidases</b>
B  Family S1: chymotrypsin family
C    ABAZ39_04275 hypothetical protein	K04775 ydgD; protease YdgD [EC:3.4.21.-] 
C    ABAZ39_02685 hypothetical protein	K04771 degP; serine protease Do [EC:3.4.21.107] 
C    ABAZ39_04295 serine protease	K04771 degP; serine protease Do [EC:3.4.21.107] 
C    ABAZ39_07055 serine protease	K04771 degP; serine protease Do [EC:3.4.21.107] 
C    ABAZ39_09025 serine protease	K04771 degP; serine protease Do [EC:3.4.21.107] 
C    ABAZ39_16055 serine protease	K04771 degP; serine protease Do [EC:3.4.21.107] 
B  Family S3: togavirin family
B  Family S6
B  Family S7: flavivirin family
B  Family S8: subtilisin family
B  Family S9: prolyl oligopeptidase family
B  Family S10
B  Family S11: D-Ala-D-Ala carboxypeptidase A family
C    ABAZ39_06680 D-Ala-D-Ala carboxypeptidase	K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] 
B  Family S12: D-Ala-D-Ala carboxypeptidase B family
C    ABAZ39_02295 beta-lactamase	K18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase [EC:3.4.16.4 3.4.21.-] 
B  Family S13: D-Ala-D-Ala peptidase C family
C    ABAZ39_21515 D-alanyl-D-alanine carboxypeptidase	K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] 
B  Family S14: ClpP endopeptidase family
C    ABAZ39_08425 clpP; Clp protease	K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] 
C    ABAZ39_17705 Clp protease	K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] 
B  Family S15
B  Family S16: lon protease family
C    ABAZ39_08410 DNA-binding protein	K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] 
C    ABAZ39_17805 DNA-binding protein	K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53] 
B  Family S21: assemblin family
B  Family S24: LexA family
C    ABAZ39_08125 LexA family transcriptional regulator	K01356 lexA; repressor LexA [EC:3.4.21.88] 
B  Family S26: signal peptidase I family
C    ABAZ39_17745 signal peptidase	K03100 lepB; signal peptidase I [EC:3.4.21.89] 
B  Family S28
B  Family S31
B  Family S32
B  Family S33
C    ABAZ39_00350 proline iminopeptidase	K01259 pip; proline iminopeptidase [EC:3.4.11.5] 
B  Family S41: C-terminal processing peptidase family
C    ABAZ39_02135 peptidase S41	K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] 
C    ABAZ39_19480 peptidase S41	K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] 
C    ABAZ39_22110 carboxyl-terminal protease	K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] 
C    ABAZ39_32770 hypothetical protein	K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] 
B  Family S45
C    ABAZ39_22635 acyl-homoserine-lactone acylase	K01434 pac; penicillin G amidase [EC:3.5.1.11] 
B  Family S49: protease IV family
C    ABAZ39_04350 protease IV	K04773 sppA; protease IV [EC:3.4.21.-] 
B  Family S50
B  Family S51
B  Family S53
B  Family S54: Rhomboid family
C    ABAZ39_07985 membrane protein	K07059 rho2; rhomboid family protease [EC:3.4.21.105] 
B  Family S55: SpoIVB peptidase family
B  Family S62
B  Family S66
B  Family S77: phage prohead processing peptidase family
B  Family S78
#
A<b>Threonine peptidases</b>
B  Family T1: proteasome family
C    ABAZ39_14210 ATP-dependent protease subunit HslV	K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2] 
B  Family T2
B  Family T3: gamma-glutamyltransferase family
C    ABAZ39_01185 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] 
C    ABAZ39_32110 gamma-glutamyltransferase	K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] 
C    ABAZ39_30245 gamma-glutamyltransferase	K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126] 
#
A<b>Peptidases of unknown catalytic type</b>
B  Family U32
C    ABAZ39_27800 protease	K24845 ubiV; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiV [EC:1.97.1.15] 
C    ABAZ39_27805 protease	K24844 ubiU; 2-(all-trans-polyprenyl)phenol 6-hydroxylase (prephenate) UbiU [EC:1.97.1.15] 
B  Family U62
C    ABAZ39_03210 modulator protein	K03592 pmbA; PmbA protein 
C    ABAZ39_04505 tldD; protease TldD	K03568 tldD; TldD protein 
#
A<b>Peptidase inhibitors</b>
B  Family I1: Kazal family
B  Family I2: Kunitz - BPTI family
B  Family I4: serpin family
B  Family I11: ecotin family
B  Family I17: WAP-type family
B  Family I25: cystatin family
B  Family I27: calpastatin family
B  Family I32: IAP family
B  Family I34: IA3 family
B  Family I35: timp family
B  Family I39: alpha2M family
C    ABAZ39_22225 alpha-2-macroglobulin	K06894 yfhM; alpha-2-macroglobulin 
B  Family I47: latexin family
B  Family I49: proSAAS family
B  Family I51: IC family
B  Family I57: staphostatin B family
B  Family I63
B  Family I80
B  Family I87
C    ABAZ39_09035 membrane protein	K04087 hflC; modulator of FtsH protease HflC 
C    ABAZ39_09040 membrane protein	K04088 hflK; modulator of FtsH protease HflK 
B  Family I93
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#Last updated: August 20, 2025
#<br>Classification taken and modified from <a href="https://www.ebi.ac.uk/merops/">MEROPS</a>