+F Repair protein KO
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DNA Repair and Recombination Proteins - Paracholeplasma brassicae
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BN85309620 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BN85312040 phrB; Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E BN85313430 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BN85307600 mutY; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BN85303570 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E BN85311930 Helicase c2 domain-containing protein K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D BN85305040 mutT; Mutator protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BN85311940 mutT; NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BN85313320 dut; DeoxyUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D BN85309620 Methylated DNA-protein cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D BN85312040 phrB; Deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E BN85313430 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E BN85307600 mutY; A/G-specific adenine DNA glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E BN85306410 mutM; Formamidopyrimidine-DNA glycosylase (Fapy-DNA glycosylase) K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E BN85303570 Endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E BN85311120 nfo; Endodeoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
D DNA ligase
E BN85315970 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E BN85306400 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E BN85312900 putative excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
E BN85315960 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E BN85312710 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E BN85305940 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E BN85315980 ATP-dependent DNA helicase, UvrD/REP K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BN85315990 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BN85306400 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E BN85315970 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F BN85303060 rpoB; DNA-directed RNA polymerase, subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F BN85303070 rpoC; DNA-directed RNA polymerase, subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F BN85302600 rpoA; DNA-directed RNA polymerase, subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F BN85316450 rpoE; Putative DNA-directed RNA polymerase, delta subunit K03048 rpoE; DNA-directed RNA polymerase subunit delta
F BN85305930 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F BN85300180 mfd; Transcription-repair coupling factor (Superfamily II helicase) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E BN85310080 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
E BN85309020 mutS; DNA mismatch repair protein MutS, truncated K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
E BN85310070 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E BN85311220 xseA; Exodeoxyribonuclease 7 large subunit XseA K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E BN85311210 xseB; putative exodeoxyribonuclease 7 small subunit XseB K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E BN85312810 dnaE; DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E BN85305120 polC; DNA polymerase III polC-type (PolIII) K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E BN85300020 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E BN85310190 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E BN85302720 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E BN85310180 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E BN85316500 dnaX; DNA polymerase III, gamma and tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E BN85315970 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E BN85315980 ATP-dependent DNA helicase, UvrD/REP K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BN85315990 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E BN85303170 ssb1; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E BN85307770 ssb2; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E BN85312180 recD; ATP-dependent exoDNAse (Exonuclease V), alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E BN85310150 recA; Recombinase A K03553 recA; recombination protein RecA
E BN85308280 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E BN85308290 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E BN85306140 priA; DNA replication factor Y K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E BN85300230 sbcC; DNA repair exonuclease, subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E BN85309430 conserved hypothetical protein (DUF2357) K03546 sbcC; DNA repair protein SbcC/Rad50
E BN85300220 sbcD; DNA repair exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E BN85310150 recA; Recombinase A K03553 recA; recombination protein RecA
E BN85300040 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E BN85303530 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E BN85307150 recO; Recombination repair protein O K03584 recO; DNA repair protein RecO (recombination protein O)
E BN85316480 recR; Recombination protein RecR K06187 recR; recombination protein RecR
E BN85311180 recN; DNA repair protein, ATPase K03631 recN; DNA repair protein RecN (Recombination protein N)
E BN85307860 recU; Holliday junction resolvase RecU K03700 recU; recombination protein U
E BN85308280 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E BN85308290 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D AddAB pathway proteins
E BN85300200 addA; ATP-dependent helicase/nuclease subunit A K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E BN85300230 sbcC; DNA repair exonuclease, subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E BN85309430 conserved hypothetical protein (DUF2357) K03546 sbcC; DNA repair protein SbcC/Rad50
E BN85300220 sbcD; DNA repair exonuclease SbcCD, D subunit K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F BN85300060 gyrA; DNA gyrase, subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F BN85300050 gyrB; DNA gyrase, subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F BN85306350 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F BN85309980 DNA binding protein, histone-like protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F BN85307150 recO; Recombination repair protein O K03584 recO; DNA repair protein RecO (recombination protein O)
F BN85316480 recR; Recombination protein RecR K06187 recR; recombination protein RecR
F BN85315970 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F BN85312900 putative excinuclease ATPase subunit K03701 uvrA; excinuclease ABC subunit A
F BN85315960 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F BN85312710 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D BN85311170 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D BN85310520 DNA-damage repair protein K03502 umuC; DNA polymerase V
C Other SOS response factors
D BN85310150 recA; Recombinase A K03553 recA; recombination protein RecA
D BN85311180 recN; DNA repair protein, ATPase K03631 recN; DNA repair protein RecN (Recombination protein N)
D BN85303170 ssb1; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BN85307770 ssb2; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D BN85306250 recX; Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D BN85305040 mutT; Mutator protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BN85311940 mutT; NTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D BN85313320 dut; DeoxyUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D BN85316230 nrdE; Ribonucleoside-diphosphate reductase, alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BN85316630 nrdA; Ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D BN85316640 nrdB; Ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D BN85316550 Exopolyphosphatase-related protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
D BN85316560 Phosphoesterase RecJ domain protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024