+E Replication protein KO
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DNA Replication Proteins - Aspergillus clavatus
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D ACLA_024800 origin recognition complex subunit Orc1, putative K02603 ORC1; origin recognition complex subunit 1
D ACLA_012410 origin recognition complex subunit 2, putative K02604 ORC2; origin recognition complex subunit 2
D ACLA_057590 hypothetical protein K02605 ORC3; origin recognition complex subunit 3
D ACLA_070130 origin recognition complex subunit Orc4, putative K02606 ORC4; origin recognition complex subunit 4
D ACLA_031900 hypothetical protein K02607 ORC5; origin recognition complex subunit 5
D ACLA_084200 hypothetical protein K02608 ORC6; origin recognition complex subunit 6
D ACLA_006010 cell division control protein Cdc6, putative K02213 CDC6; cell division control protein 6
D ACLA_041360 DNA replication licensing factor Mcm2, putative K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D ACLA_030670 DNA replication licensing factor MCM3 K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D ACLA_080870 DNA replication licensing factor MCM4 K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D ACLA_002640 DNA replication licensing factor Mcm5, putative K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D ACLA_013890 DNA replication licensing factor Mcm6, putative K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D ACLA_069170 DNA replication licensing factor Mcm7, putative K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
D ACLA_033550 cell cycle protein kinase, putative K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
D ACLA_083210 DBF zinc finger domain protein K02309 DBF4; regulatory subunit for Cdc7p protein kinase
C GINS complex
D ACLA_051420 PSF1 domain protein K10732 GINS1; GINS complex subunit 1
D ACLA_070050 DNA replication complex GINS protein (Psf2), putative K10733 GINS2; GINS complex subunit 2
D ACLA_050690 GINS complex subunit Psf3, putative K10734 GINS3; GINS complex subunit 3
D ACLA_082460 GINS DNA replication complex subunit Sld5, putative K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D ACLA_016370 subunit of DNA polymerase II K03507 DPB11; DNA replication regulator DPB11
D ACLA_020010 cell division control protein 45, putative K06628 CDC45; cell division control protein 45
D ACLA_038150 DNA replication protein, putative K10736 MCM10; minichromosome maintenance protein 10
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D ACLA_069720 DNA polymerase alpha catalytic subunit, putative K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D ACLA_016000 DNA polymerase alpha/primase associated subunit K02321 POLA2; DNA polymerase alpha subunit B
D ACLA_036970 DNA primase subunit Pri1, putative K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D ACLA_031200 DNA primase large subunit K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D ACLA_037330 DNA polymerase epsilon, catalytic subunit A/POL2, putative K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D ACLA_068130 DNA polymerase epsilon subunit B, putative K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
C DNA polymerase delta complex
D ACLA_075510 DNA polymerase delta large chain K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D ACLA_047340 DNA polymerase delta subunit 2, putative K02328 POLD2; DNA polymerase delta subunit 2
D ACLA_075620 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D ACLA_084290 DNA polymerase delta subunit 4, putative K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
D ACLA_015680 DNA polymerase gamma K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
C RPA (replication protein A)
D ACLA_068000 replication factor A 1, rfa1 K07466 RFA1; replication factor A1
D ACLA_084790 possible replication factor-a protein K10739 RFA2; replication factor A2
C RFC (replication factor C)
D ACLA_071100 chromosome transmission fidelity factor K10754 RFC1; replication factor C subunit 1
D ACLA_036280 DNA replication factor C subunit Rfc2, putative K10755 RFC2_4; replication factor C subunit 2/4
D ACLA_095520 DNA replication factor C subunit Rfc4, putative K10755 RFC2_4; replication factor C subunit 2/4
D ACLA_071120 DNA replication factor C subunit Rfc5, putative K10756 RFC3_5; replication factor C subunit 3/5
D ACLA_003460 DNA replication factor C subunit Rfc3, putative K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D ACLA_025490 reverse transcriptase, RNaseH, putative K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D ACLA_027410 RNase H domain protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D ACLA_027000 ribonuclease HI large subunit K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D ACLA_089130 hypothetical protein K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D ACLA_029740 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D ACLA_051220 DNA replication helicase Dna2, putative K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D ACLA_094400 DNA helicase, putative K19783 HCS1; DNA polymerase alpha-associated DNA helicase A [EC:5.6.2.3]
D ACLA_034020 Flap endonuclease, putative K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D ACLA_037000 exonuclease, putative K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D ACLA_080840 DNA ligase Cdc9, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D ACLA_076130 hypothetical protein K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D ACLA_096870 C-5 cytosine methyltransferase DmtA K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
E ACLA_075070 telomere-binding protein alpha subunit, central domain, putative K11109 POT1; protection of telomeres protein 1
E ACLA_081720 hypothetical protein K11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
E ACLA_063800 SIR2 family histone deacetylase, putative K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
E ACLA_051130 chromatin regulatory protein sir2 K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
E ACLA_068430 SIR2 family histone deacetylase, putative K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
E ACLA_024990 SIR2 family histone deacetylase (Hst4), putative K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
C Telomerase complex (animals)
D ACLA_006280 telomerase reverse transcriptase K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E ACLA_052640 snoRNP protein (gar1), putative K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E ACLA_021850 ribosome biogenesis protein Nhp2 K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E ACLA_001170 Nop10 family nucleolar RNA-binding protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E ACLA_008990 centromere/microtubule binding protein cbf5 K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D ACLA_006280 telomerase reverse transcriptase K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E ACLA_047110 small nuclear ribonucleoprotein SmB, putative K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E ACLA_089530 small nuclear ribonucleoprotein SmD1, putative K11087 SNRPD1; small nuclear ribonucleoprotein D1
E ACLA_015740 small nuclear ribonucleoprotein SmD2, putative K11096 SNRPD2; small nuclear ribonucleoprotein D2
E ACLA_049460 small nuclear ribonucleoprotein SmD3, putative K11088 SNRPD3; small nuclear ribonucleoprotein D3
E ACLA_007670 small nuclear ribonucleoprotein SmE, putative K11097 SNRPE; small nuclear ribonucleoprotein E
E ACLA_074440 LSM domain protein K11098 SNRPF; small nuclear ribonucleoprotein F
E ACLA_058360 small nuclear ribonucleoprotein SmG, putative K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D ACLA_036280 DNA replication factor C subunit Rfc2, putative K10755 RFC2_4; replication factor C subunit 2/4
D ACLA_095520 DNA replication factor C subunit Rfc4, putative K10755 RFC2_4; replication factor C subunit 2/4
D ACLA_071120 DNA replication factor C subunit Rfc5, putative K10756 RFC3_5; replication factor C subunit 3/5
D ACLA_003460 DNA replication factor C subunit Rfc3, putative K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D ACLA_085070 meiotic recombination protein Mre11 K10865 MRE11; double-strand break repair protein MRE11
D ACLA_051660 DNA repair protein Rad50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
C Other termination factors
D ACLA_015700 ataxia telangiectasia mutated (atm) K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D ACLA_089690 RecQ family helicase MusN K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D ACLA_097940 DNA repair protein RAD1, putative K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D ACLA_010570 poly(ADP)-ribose polymerase PARP, putative K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D ACLA_005360 G-patch domain protein K11135 PINX1; Pin2-interacting protein X1
D ACLA_073900 hypothetical protein K11137 TELO2; telomere length regulation protein
D ACLA_016360 mitochondrial DNA helicase (Pif1), putative K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D ACLA_084470 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
D ACLA_085900 hypothetical protein K25059 SDE2; replication stress response regulator SDE2
D ACLA_005800 DUF602 domain protein K25186 RTF2; replication termination factor 2
D ACLA_014560 MYB DNA binding protein (Tbf1), putative K22485 TBF1; protein TBF1
B DNA Topoisomerases
C ACLA_031120 topoisomerase I K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C ACLA_087000 DNA topoisomerase II K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C ACLA_092130 DNA topoisomerase III, putative K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E ACLA_025490 reverse transcriptase, RNaseH, putative K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E ACLA_027410 RNase H domain protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E ACLA_025490 reverse transcriptase, RNaseH, putative K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E ACLA_027410 RNase H domain protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E ACLA_051220 DNA replication helicase Dna2, putative K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E ACLA_034020 Flap endonuclease, putative K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E ACLA_080840 DNA ligase Cdc9, putative K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022