+F Repair protein KO #

  DNA Repair and Recombination Proteins - Actimicrobium sp. CCC2.4

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D RHM62_18775 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D RHM62_02040 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D RHM62_11525 FAD-binding domain-containing protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D RHM62_01815 FAD-binding domain-containing protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D RHM62_04965 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E RHM62_10565 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E RHM62_03540 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E RHM62_06760 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex E RHM62_13425 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3] D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D RHM62_04410 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D RHM62_17195 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D RHM62_18775 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D RHM62_02040 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D RHM62_11525 FAD-binding domain-containing protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D RHM62_01815 FAD-binding domain-containing protein K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D RHM62_04965 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D RHM62_03345 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13] C BER (base exicision repair) D DNA glycosylases E RHM62_10565 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E RHM62_14430 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E RHM62_15190 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E RHM62_02045 AlkA N-terminal domain-containing protein K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E RHM62_03540 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E RHM62_01940 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E RHM62_03530 mutM; bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E RHM62_06760 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E RHM62_07445 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] E RHM62_02605 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2] D RecJ E RHM62_10655 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] D DNA ligase E RHM62_12650 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E RHM62_18235 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E RHM62_00390 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A E RHM62_01800 excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A E RHM62_10560 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B E RHM62_08690 uvrC; excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C E RHM62_01835 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E RHM62_05125 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E RHM62_18235 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E RHM62_12650 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F RHM62_00755 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F RHM62_00750 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F RHM62_00590 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F RHM62_14650 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F RHM62_11055 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors E RHM62_11970 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS D Molecular matchmaker E RHM62_18835 mutL; DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL D Strand discrimination factor D DNA exonucleases E RHM62_18000 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] E RHM62_17415 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E RHM62_05210 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E RHM62_18445 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E RHM62_01790 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E RHM62_05550 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7] E RHM62_03750 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E RHM62_10115 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E RHM62_07690 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E RHM62_12210 exonuclease domain-containing protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E RHM62_16015 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E RHM62_16355 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E RHM62_12650 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E RHM62_01835 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E RHM62_05125 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E RHM62_00385 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E RHM62_18295 recA; recombinase RecA K03553 recA; recombination protein RecA E RHM62_03585 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA E RHM62_03590 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E RHM62_03580 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E RHM62_01560 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] E RHM62_10310 priB; primosomal replication protein N K02686 priB; primosomal replication protein N E RHM62_18000 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] E RHM62_10070 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50 E RHM62_10075 exonuclease SbcCD subunit D C-terminal domain-containing protein K03547 sbcD; DNA repair protein SbcD/Mre11 D RecFOR pathway proteins E RHM62_18295 recA; recombinase RecA K03553 recA; recombination protein RecA E RHM62_14410 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms E RHM62_05275 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E RHM62_10655 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] E RHM62_08670 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) E RHM62_16345 recR; recombination mediator RecR K06187 recR; recombination protein RecR E RHM62_18145 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) E RHM62_13130 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC E RHM62_03585 ruvA; Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA E RHM62_03590 ruvB; Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E RHM62_03580 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins E RHM62_05455 UvrD-helicase domain-containing protein K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-] E RHM62_05450 PD-(D/E)XK nuclease family protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-] D Other HR factor D Archaeal homologous recombinant proteins E RHM62_10070 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50 E RHM62_10075 exonuclease SbcCD subunit D C-terminal domain-containing protein K03547 sbcD; DNA repair protein SbcD/Mre11 E RHM62_05720 DUF853 domain-containing protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F RHM62_17610 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F RHM62_01795 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] E Supressor F RHM62_16130 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F RHM62_10655 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-] F RHM62_08670 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O) F RHM62_16345 recR; recombination mediator RecR K06187 recR; recombination protein RecR F RHM62_12650 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator F RHM62_03570 helix-turn-helix domain-containing protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein F RHM62_06425 integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha F RHM62_17570 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta E Supressor F RHM62_18000 sbcB; exodeoxyribonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1] F RHM62_18375 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F RHM62_00390 uvrA; excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A F RHM62_01800 excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A F RHM62_10560 uvrB; excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B F RHM62_16375 H-NS histone family protein K03746 hns; DNA-binding protein H-NS B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D RHM62_01530 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D RHM62_09510 Y-family DNA polymerase K03502 umuC; DNA polymerase V D RHM62_09585 Y-family DNA polymerase K03502 umuC; DNA polymerase V D RHM62_09505 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-] D RHM62_09580 umuD; translesion error-prone DNA polymerase V autoproteolytic subunit K03503 umuD; DNA polymerase V [EC:3.4.21.-] C Other SOS response factors D RHM62_18295 recA; recombinase RecA K03553 recA; recombination protein RecA D RHM62_10300 lexA; transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D RHM62_18145 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N) D RHM62_12215 imuA; translesion DNA synthesis-associated protein ImuA K14160 imuA; protein ImuA D RHM62_12220 DNA polymerase Y family protein K14161 imuB; protein ImuB D RHM62_14255 error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D RHM62_00385 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D RHM62_18290 recX; recombination regulator RecX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D RHM62_01540 UvrD-helicase domain-containing protein K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4] D RHM62_15415 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] C Modulation of nucleotide pools D RHM62_04410 NUDIX domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D RHM62_17195 dut; dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D RHM62_04570 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D RHM62_05240 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D RHM62_04575 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024