+D Transcription factors KO
#
Transcription Factors - Actinoplanes sp. N902-109
%
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AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
C AP-1(-like) components, Fos
C AP-1(-like) components, Maf
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
C CREB
C C/EBP-like factors
C bZIP/PAR
C Plant bZIP factors
C ZIP only
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
C Myogenic transcription factors
C Achaete-Scute
C Tal/Twist/Atonal/Hen, Lymphoid factors
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
C Tal/Twist/Atonal/Hen, HEN
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
C Hairy, Fungal regulators
C Factors with PAS domain
C Yabby
C INO
C HLH domain only
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
C Cell cycle controlling factors, Myc
C Cell cycle controlling factors, Mad/Max
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
C RF-X
C AP-2 (bHSH)
B Zinc finger
C Cys4 thyroid hormone receptor-like
C Cys4 hepatocyte nuclear factor 4-like
C Cys4 estrogen receptor-like
C Cys4 nerve growth factor IB-like
C Cys4 Fushi tarazu-F1-like
C Cys4 germ cell nuclear factor
C Cys4 Knirps/DAX1-like
C Cys4 GATA-factors
C Cys2His2 SP/KLF family and related proteins
C Cys2His2 GLI-like
C Cys2His2 Snail
C Cys2His2 BTB-ZF factors
C Cys2His2 BED
C Cys2His2 PRDM
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
C Cys2HisCys zinc factors
C Cys3His zinc factors
C Cys2CysHis zinc factors
C CXXC CpG-binding proteins
D L083_0210 putative SacI methylase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D L083_8016 DNA-cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
B Helix-turn-helix
C Homeo domain ANTP: HOXL
C Homeo domain ANTP: NKL
C Homeo domain Paired-related
C Homeo domain LIM
C Homeo domain POU
C Homeo domain SINE
C Homeo domain ZF
C Homeo domain CUT
C Homeo domain PROS
C Homeo domain TALE
C Homeo domain other
C Fork head/winged helix developmental regulators
C Fork head/winged helix tissue-specific regulators
C Fork head/winged helix cell cycle-controlling factors, E2F
C Fork head/winged helix cell cycle-controlling factors, DP
C Fork head/winged helix other regulators
C Stork head/winged helix factors
C Heat shock factors
C Tryptophan clusters Myb, Myb-factors
C Tryptophan clusters Myb, Myb-like factors
C Tryptophan clusters Ets-type
C Tryptophan clusters interferon-regulating factors
C TEA domain
C ARID
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
C RHR (Rel homology region) Ankyrin only
C RHR (Rel homology region) NF-AT
C STAT
C p53
C MADS-box regulators of differentiation, MEF-2
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
C SAND domain-containing proteins
C TATA-binding proteins
C HMG SOX
C HMG TCF-1
C HMG TOX
C HMG2-related
C UBF
C Other HMG box factors
C Heteromeric CCAAT factors
C Grainyhead
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
C Cold-shock domain factors, FRG Y2-like
C Runt
C MYRF
B Other transcription factors
C HMGI(Y)
C NUPR
C Pocket domain Rb
C Pocket domain CBP
C T-box
C DMRT
C LRRFIP
C TCP
C AP2/ERF
C WRKY
C LOB
C GRAS
C Copper-fist proteins fungal regulators
C Others
#
AProkaryotic type
B Helix-turn-helix
C AraC family
D L083_5829 AraC family transcriptional regulator K18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA
D L083_4614 AraC family transcriptional regulator K13653 K13653; AraC family transcriptional regulator
D L083_3215 helix-turn-helix domain-containing protein K07506 K07506; AraC family transcriptional regulator
D L083_7439 AraC family transcriptional regulator K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D L083_1251 AraC family transcription regulator K13633 ftrA; AraC family transcriptional regulator, transcriptional activator FtrA
C LysR family
D L083_7291 chromosome replication initiation inhibitor protein K05596 argP; LysR family transcriptional regulator, arginine and lysine transport system/DNA replication regulator
C DeoR family
D L083_4538 DeoR family transcriptional regulator K02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor
D L083_7799 DeoR family transcriptional regulator K02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor
D L083_0645 DeoR family transcriptional regulator K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor
C LacI family
D L083_0734 putative DNA-binding protein K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_3748 transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_3789 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_3892 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_4160 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_4463 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_4618 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_4635 bxlR; LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_5579 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_5591 LacI family transcription regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_6227 rbsR; LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_6346 LacI family transcription regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_6489 transcriptional regulator, LacI family K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D L083_7281 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
C GntR family
D L083_4575 yvoA; transcriptional regulator K03710 K03710; GntR family transcriptional regulator
D L083_5102 UbiC transcriptional regulator-associated domain-containing protein K03710 K03710; GntR family transcriptional regulator
D L083_2058 transcriptional regulator, GntR family K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
D L083_4314 GntR family transcriptional regulator K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
C TetR/AcrR family
D L083_7395 TetR family transcriptional regulator K19736 aefR; TetR/AcrR family transcriptional regulator, regulator of autoinduction and epiphytic fitness
D L083_2423 TetR family transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D L083_2533 TetR family transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D L083_4659 TetR family transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D L083_5536 TetR family transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D L083_1689 TetR family transcriptional regulator K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
D L083_0661 TetR family transcriptional regulator K21961 ethR; TetR/AcrR family transcriptional regulator, ethionamide resistance regulator
D L083_2207 mtrR; regulatory protein TetR K21962 acnR; TetR/AcrR family transcriptional regulator, transcriptional repressor of aconitase
D L083_2540 TetR family transcriptional regulator K22295 K22295; TetR/AcrR family transcriptional regulator, repressor for neighboring sulfatase
C Lrp/AsnC family
D L083_4200 AsnC family transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D L083_0324 AsnC family transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D L083_1183 transcriptional regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D L083_2405 AsnC family transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D L083_3915 AsnC family transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D L083_7758 AsnC family transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
C LuxR family
D L083_0769 LuxR family transcriptional regulator K01994 gerE; LuxR family transcriptional regulator, transcriptional regulator of spore coat protein
D L083_6591 LuxR family transcriptional regulator K21685 ramA; LuxR family transcriptional regulator, regulator of acetate metabolism
C MarR family
D L083_1955 MarR family transcriptional regulator K06075 slyA; MarR family transcriptional regulator, transcriptional regulator for hemolysin
D L083_2731 MarR family transcriptional regulator K22296 nicR; MarR family transcriptional regulator, lower aerobic nicotinate degradation pathway regulator
D L083_2303 regulatory protein MarR K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
D L083_3961 hypothetical protein K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
D L083_4561 MarR-family transcriptional regulator K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
D L083_4993 regulatory protein MarR K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
D L083_8056 MarR family transcriptional regulator K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
C MerR family
D L083_2191 MerR family transcriptional regulator K19591 cueR; MerR family transcriptional regulator, copper efflux regulator
D L083_8099 soxR; redox-sensitive transcriptional activator SoxR K13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR
D L083_0104 hspR; MerR family transcriptional regulator K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D L083_6826 putative transcriptional regulator, MerR family K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D L083_0166 regulatory protein MerR K22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator
C Fur family
D L083_1620 zinc uptake regulator K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D L083_7747 ferric uptake regulator family protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D L083_3486 fur family ferric uptake regulator K22297 furA; Fur family transcriptional regulator, stress-responsive regulator
D L083_7594 fur; fur family ferric uptake regulator K22297 furA; Fur family transcriptional regulator, stress-responsive regulator
C IclR family
D L083_3703 transcriptional regulator, IclR family K13641 iclR; IclR family transcriptional regulator, acetate operon repressor
D L083_0824 kdgR; IclR family transcriptional regulator K02624 pcaR; IclR family transcriptional regulator, pca regulon regulatory protein
C CRP/FNR family
D L083_1933 crp/Fnr family transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D L083_3465 Crp/Fnr family transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D L083_5258 Crp/Fnr family transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D L083_5432 transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D L083_7903 hlyX; Crp/Fnr family transcriptional regulator K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
C Rrf2 family
C ArsR family
D L083_0113 cadC; ArsR family transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D L083_2118 ArsR family transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D L083_5728 ArsR family transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D L083_8047 ArsR family transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D L083_1621 regulatory protein ArsR K22298 smtB; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor
C XRE family
D L083_4981 XRE family transcriptional regulator K21686 prpR; XRE family transcriptional regulator, fatty acid utilization regulator
D L083_6779 helix-turn-helix domain-containing protein K27043 clgR; XRE family transcriptional regulator, stress-response regulator
C PadR family
D L083_0503 transcriptional regulator, PadR-like family K10947 K10947; PadR family transcriptional regulator
D L083_1095 PadR family transcriptional regulator K10947 K10947; PadR family transcriptional regulator
D L083_1415 PadR-like family transcriptional regulator K10947 K10947; PadR family transcriptional regulator
D L083_3170 PadR-like family transcriptional regulator K10947 K10947; PadR family transcriptional regulator
C Other families
D L083_6721 ideR; iron (metal) dependent repressor K26252 dtxR; DtxR family transcriptional regulator, iron-dependent repressor
D L083_4585 transcriptional repressor, CopY family K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
D L083_7474 birA; biotin-acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D L083_7648 rex; redox-sensing transcriptional repressor Rex K01926 rex; redox-sensing transcriptional repressor
D L083_6943 helix-turn-helix domain-containing protein K07729 K07729; putative transcriptional regulator
B Ribbon-helix-helix
C CopG family
C Other families
B Other transcription factors
C BglG family
C Others
D L083_1013 wblB; transcriptional regulator WhiD K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D L083_1156 transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D L083_7210 transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D L083_7225 transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D L083_7913 transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D L083_7263 transcription factor WhiB K18958 whiB7; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D L083_0853 hypothetical protein K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D L083_0222 hypothetical protein K22894 embR; SARP family transcriptional regulator, regulator of embCAB operon
D L083_2438 putative pathway specific activator K22894 embR; SARP family transcriptional regulator, regulator of embCAB operon
D L083_2909 SARP family transcriptional regulator K22894 embR; SARP family transcriptional regulator, regulator of embCAB operon
D L083_7154 putative transcription activator K22894 embR; SARP family transcriptional regulator, regulator of embCAB operon
D L083_8205 parB; parb-like partition protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D L083_7838 transcription factor CarD K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
D L083_5869 arginine repressor ArgR K03402 argR; transcriptional regulator of arginine metabolism
D L083_1557 hrcA; heat-inducible transcription repressor K03705 hrcA; heat-inducible transcriptional repressor
D L083_3166 phenylacetic acid degradation operon negative regulatory protein PaaX K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
D L083_3180 PaaX family transcriptional regulator K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
D L083_5552 PaaX domain-containing protein domain K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
D L083_7626 paaX; PaaX family transcriptional regulator K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
D L083_5932 pyrR; bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D L083_6858 hypothetical protein K07733 alpA; prophage regulatory protein
D L083_2222 FMN-binding negative transcriptional regulator K07734 paiB; transcriptional regulator
D L083_1199 hypothetical protein K07735 algH; putative transcriptional regulator
D L083_2030 TraR/DksA family transcriptional regulator K06204 dksA; RNA polymerase-binding transcription factor
D L083_5141 zinc finger protein K06204 dksA; RNA polymerase-binding transcription factor
D L083_6729 nrdR; transcriptional regulator NrdR K07738 nrdR; transcriptional repressor NrdR
D L083_2010 MraZ protein K03925 mraZ; transcriptional regulator MraZ
!
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 21, 2025
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Classification taken and modified from TRANSFAC 7.0