+D GTP-binding proteins KO
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GTP-Binding Proteins - Athene cunicularia (burrowing owl)
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AHeterotrimeric G-proteins
B Alpha Subunits
C Alpha type 1 (Gi/o) [OT]
D 113490430 GNAI3; guanine nucleotide-binding protein G(k) subunit alpha K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
D 113491350 GNAI1; guanine nucleotide-binding protein G(i) subunit alpha-1 K04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha
D 113484271 GNAO1; guanine nucleotide-binding protein G(o) subunit alpha K04534 GNAO; guanine nucleotide-binding protein G(o) subunit alpha
D 113484903 guanine nucleotide-binding protein G(t) subunit alpha-1-like K04631 GNAT1_2; guanine nucleotide-binding protein G(t) subunit alpha 1/2
D 113484699 guanine nucleotide-binding protein G(t) subunit alpha-1 K04631 GNAT1_2; guanine nucleotide-binding protein G(t) subunit alpha 1/2
D 113491144 GNAT3; guanine nucleotide-binding protein G(t) subunit alpha-3 K19729 GNAT3; guanine nucleotide-binding protein G(t) subunit alpha 3
D 113486090 GNAZ; guanine nucleotide-binding protein G(z) subunit alpha K04535 GNAZ; guanine nucleotide-binding protein G(z) subunit alpha
C Alpha type 2 (Gs)
D 113487624 GNAS; guanine nucleotide-binding protein G(s) subunit alpha K04632 GNAS; guanine nucleotide-binding protein G(s) subunit alpha
D 113476214 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha K04633 GNAL; guanine nucleotide-binding protein G(olf) subunit alpha
C Alpha type 3 (Gq/11) [OT]
D 113489960 guanine nucleotide-binding protein G(q) subunit alpha-like K04634 GNAQ; guanine nucleotide-binding protein G(q) subunit alpha
D 113489339 guanine nucleotide-binding protein subunit alpha-11 K04635 GNA11; guanine nucleotide-binding protein subunit alpha-11
D 113489961 LOW QUALITY PROTEIN: guanine nucleotide-binding protein subunit alpha-14-like K04636 GNA14; guanine nucleotide-binding protein subunit alpha-14
C Alpha type 4 (G12/13)
D 113485647 GNA12; guanine nucleotide-binding protein subunit alpha-12 K04346 GNA12; guanine nucleotide-binding protein subunit alpha-12
D 113486831 GNA13; guanine nucleotide-binding protein subunit alpha-13 K04639 GNA13; guanine nucleotide-binding protein subunit alpha-13
C Alpha others - lower eukaryotes
B Beta Subunits
C Beta [OT]
D 113487802 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 K04536 GNB1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
D 113477022 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 K07825 GNB3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
D 113483427 GNB4; guanine nucleotide-binding protein subunit beta-4 K04538 GNB4; guanine nucleotide-binding protein subunit beta-4
D 113484224 GNB5; guanine nucleotide-binding protein subunit beta-5 K04539 GNB5; guanine nucleotide-binding protein subunit beta-5
B Gamma Subunits
C Gamma [OT]
D 113480766 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 K07826 GNG2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
D 113478536 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 K04541 GNG4; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4
D 113482841 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 K04542 GNG5; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5
D 113490204 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 K04545 GNG10; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
D 113477046 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11-like K04546 GNG11; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11
D 113482585 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 K04347 GNG12; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
D 113489179 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 K04549 GNGT2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
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ASmall (monomeric) G-proteins
B Ras Family
C Ras [OT]
D 113481169 HRAS; GTPase HRas K02833 HRAS; GTPase HRas
D 113491163 KRAS; GTPase KRas isoform X1 K07827 KRAS; GTPase KRas
D 113488912 NRAS; GTPase NRas K07828 NRAS; GTPase NRas
D 113481185 RRAS2; ras-related protein R-Ras2 K07830 RRAS2; Ras-related protein R-Ras2
D 113482327 MRAS; ras-related protein M-Ras K07831 MRAS; Ras-related protein M-Ras
C Rit
D 113488731 RIT1; GTP-binding protein Rit1 K07832 RIT1; Ras-like without CAAX 1
D 113489655 RIT2; GTP-binding protein Rit2 isoform X1 K07833 RIT2; Ras-like without CAAX 2
C Ral
D 113477514 RALA; ras-related protein Ral-A K07834 RALA; Ras-related protein Ral-A
D 113482304 RALB; ras-related protein Ral-B K07835 RALB; Ras-related protein Ral-B
C Rap [OT]
D 113488776 RAP1A; ras-related protein Rap-1A K04353 RAP1A; Ras-related protein Rap-1A
D 113487398 RAP1B; ras-related protein Rap-1b K07836 RAP1B; Ras-related protein Rap-1B
D 113480184 RAP2C; ras-related protein Rap-2c K07839 RAP2C; Ras-related protein Rap-2C
C Di-Ras [OT]
D 113483136 DIRAS3; GTP-binding protein Di-Ras3 K07841 DIRAS2; DIRAS family, GTP-binding Ras-like 2
D 113490143 DIRAS2; GTP-binding protein Di-Ras2 K07841 DIRAS2; DIRAS family, GTP-binding Ras-like 2
C RasD
D 113485678 RASD1; dexamethasone-induced Ras-related protein 1 K07843 RASD1; RAS, dexamethasone-induced Ras-related protein 1
D 113475917 RASD2; GTP-binding protein Rhes K07844 RASD2; RASD family, member 2
C Rad/Gem/Kir [OT]
D 113476349 GEM; GTP-binding protein GEM K07846 GEM; GTP binding protein overexpressed in skeletal muscle
D 113487714 REM1; GTP-binding protein REM 1 K07847 REM1; Rad and Gem related GTP binding protein 1
C Rheb
D 113477285 RHEB; GTP-binding protein Rheb K07208 RHEB; Ras homolog enriched in brain
C Nki-Ras
D 113489133 NKIRAS2; NF-kappa-B inhibitor-interacting Ras-like protein 2 K17197 NKIRAS; NF-kappa-B inhibitor-interacting Ras-like protein
D 113476949 NKIRAS1; NF-kappa-B inhibitor-interacting Ras-like protein 1 K17197 NKIRAS; NF-kappa-B inhibitor-interacting Ras-like protein
C Others
D 113487245 RASL10B; ras-like protein family member 10B isoform X1 K07851 RASL10B; Ras-like protein family member 10B
D 113485972 RASL11A; ras-like protein family member 11A K07852 RASL11A; Ras-like protein family member 11A
D 113480250 ras-like protein family member 11A-like K07852 RASL11A; Ras-like protein family member 11A
D 113479409 RASL11B; ras-like protein family member 11B K07853 RASL11B; Ras-like protein family member 11B
D 113483973 RASL12; ras-like protein family member 12 K07854 RASL12; Ras-like protein family member 12
D 113491422 RERG; ras-related and estrogen-regulated growth inhibitor K07855 RERG; Ras-related and estrogen-regulated growth inhibitor
D 113484056 ras-related and estrogen-regulated growth inhibitor-like protein isoform X1 K17198 RERGL; Ras-related and estrogen-regulated growth inhibitor-like protein
D 113475859 RERGL; ras-related and estrogen-regulated growth inhibitor-like protein K17198 RERGL; Ras-related and estrogen-regulated growth inhibitor-like protein
B Rho Family
C RhoA/B/C [OT]
D 113485019 RHOA; transforming protein RhoA K04513 RHOA; Ras homolog gene family, member A
D 113478531 RHOB; rho-related GTP-binding protein RhoB K07856 RHOB; Ras homolog gene family, member B
D 113488804 RHOC; rho-related GTP-binding protein RhoC K07857 RHOC; Ras homolog gene family, member C
C Rnd [OT]
D 113482172 RND3; rho-related GTP-binding protein RhoE K07859 RND3; Rho family GTPase 3
C Rac/Cdc42 [OT]
D 113485871 RAC1; ras-related C3 botulinum toxin substrate 1 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
D 113490117 RAC2; ras-related C3 botulinum toxin substrate 2 K07860 RAC2; Ras-related C3 botulinum toxin substrate 2
D 113486843 RAC3; ras-related C3 botulinum toxin substrate 3 K07861 RAC3; Ras-related C3 botulinum toxin substrate 3
D 113479888 RHOG; rho-related GTP-binding protein RhoG K07863 RHOG; Ras homolog gene family, member G
D 113487836 CDC42; cell division control protein 42 homolog isoform X1 K04393 CDC42; cell division control protein 42
D 113480594 RHOJ; rho-related GTP-binding protein RhoJ K07864 RHOJ; Ras homolog gene family, member J
D 113477693 RHOQ; rho-related GTP-binding protein RhoQ isoform X1 K07194 RHOQ; Ras homolog gene family, member Q
D 113479279 RHOH; rho-related GTP-binding protein RhoH K07873 RHOH; Ras homolog gene family, member H
D 113478640 RHOU; rho-related GTP-binding protein RhoU K07865 RHOU; Ras homolog gene family, member U
D 113480561 RHOV; rho-related GTP-binding protein RhoV K07866 RHOV; Ras homolog gene family, member V
C RhoBTB
D 113481932 RHOBTB1; rho-related BTB domain-containing protein 1 K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
C Miro
D 113486725 RHOT1; mitochondrial Rho GTPase 1 isoform X1 K07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]
D 113485549 RHOT2; mitochondrial Rho GTPase 2 isoform X1 K07871 RHOT2; mitochondrial Rho GTPase 2 [EC:3.6.5.-]
C Others
D 113486063 RHOF; rho-related GTP-binding protein RhoF K07872 RHOF; Ras homolog gene family, member F
D 113487766 IFT27; intraflagellar transport protein 27 homolog K07934 IFT27; intraflagellar transport protein 27
B Rab Family
C Rab1/35 [OT]
D 113478002 RAB1A; LOW QUALITY PROTEIN: ras-related protein Rab-1A K07874 RAB1A; Ras-related protein Rab-1A
D 113486195 RAB35; ras-related protein Rab-35 K07876 RAB35; Ras-related protein Rab-35
C Rab2/4/14 [OT]
D 113476225 RAB2A; ras-related protein Rab-2A K07877 RAB2A; Ras-related protein Rab-2A
D 113478562 RAB4A; ras-related protein Rab-4A K07879 RAB4A; Ras-related protein Rab-4A
D 113486457 RAB14; ras-related protein Rab-14 K07881 RAB14; Ras-related protein Rab-14
C Rab3/27 [OT]
D 113483105 RAB3B; ras-related protein Rab-3B K06108 RAB3B; Ras-related protein Rab-3B
D 113489651 RAB3C; ras-related protein Rab-3C K07883 RAB3C; Ras-related protein Rab-3C
D 113483926 RAB27A; ras-related protein Rab-27A K07885 RAB27A; Ras-related protein Rab-27A
D 113489851 RAB27B; LOW QUALITY PROTEIN: ras-related protein Rab-27B K07886 RAB27B; Ras-related protein Rab-27B
C Rab5/17/22/31 [OT]
D 113476514 RAB5A; ras-related protein Rab-5A K07887 RAB5A; Ras-related protein Rab-5A
D 113489175 RAB5C; ras-related protein Rab-5C K07889 RAB5C; Ras-related protein Rab-5C
D 113482276 RAB17; ras-related protein Rab-17 K07909 RAB17; Ras-related protein Rab-17
D 113476106 RAB31; ras-related protein Rab-31 K07891 RAB22; Ras-related protein Rab-22
D 113487584 RAB22A; ras-related protein Rab-22A K07891 RAB22; Ras-related protein Rab-22
C Rab6/41 [OT]
D 113479894 RAB41; ras-related protein Rab-41 isoform X1 K07893 RAB6A; Ras-related protein Rab-6A
D 113480855 RAB6A; ras-related protein Rab-6A K07893 RAB6A; Ras-related protein Rab-6A
C Rab7/9 [OT]
D 113484813 RAB7A; ras-related protein Rab-7a K07897 RAB7A; Ras-related protein Rab-7A
D 113491307 RAB9A; ras-related protein Rab-9A K07899 RAB9A; Ras-related protein Rab-9A
D 113479937 RAB9B; ras-related protein Rab-9B K07900 RAB9B; Ras-related protein Rab-9B
C Rab8/10/13 [OT]
D 113489287 RAB8A; ras-related protein Rab-8A K07901 RAB8A; Ras-related protein Rab-8A
D 113484053 RAB8B; ras-related protein Rab-8B isoform X1 K07902 RAB8B; Ras-related protein Rab-8B
D 113476125 ras-related protein Rab-10-like K07903 RAB10; Ras-related protein Rab-10
D 113478815 RAB10; ras-related protein Rab-10 K07903 RAB10; Ras-related protein Rab-10
C Rab11/25 [OT]
D 113483969 RAB11A; ras-related protein Rab-11A K07904 RAB11A; Ras-related protein Rab-11A
D 113489435 RAB11B; ras-related protein Rab-11B K07905 RAB11B; Ras-related protein Rab-11B
D 113490937 RAB25; ras-related protein Rab-25 K07906 RAB25; Ras-related protein Rab-25
C Rab12/18
D 113489256 ras-related protein Rab-18-B-like K07910 RAB18; Ras-related protein Rab-18
D 113477201 RAB18; ras-related protein Rab-18 K07910 RAB18; Ras-related protein Rab-18
C Rab15
C Rab19/30/43 [OT]
D 113488574 RAB19; ras-related protein Rab-19 K17047 RAB19; Ras-related protein Rab-19
D 113479616 RAB30; ras-related protein Rab-30 K07917 RAB30; Ras-related protein Rab-30
D 113484936 RAB43; ras-related protein Rab-43 K07930 RAB43; Ras-related protein Rab-43
C Rab20/21/24 [OT]
D 113480208 RAB20; ras-related protein Rab-20 K07911 RAB20; Ras-related protein Rab-20
D 113485239 RAB24; ras-related protein Rab-24 K07912 RAB24; Ras-related protein Rab-24
C Rab23
D 113477747 RAB23; ras-related protein Rab-23 K06234 RAB23; Ras-related protein Rab-23
C Rab26/37
D 113485572 RAB26; ras-related protein Rab-26 K07913 RAB26; Ras-related protein Rab-26
D 113486825 RAB37; ras-related protein Rab-37 K07914 RAB37; Ras-related protein Rab-37
C Rab28
D 113479182 RAB28; ras-related protein Rab-28 K07915 RAB28; Ras-related protein Rab-28
C Rab29/32/38 [OT]
D 113488870 RAB29; ras-related protein Rab-7L1 K07916 RAB7L1; Ras-related protein Rab-7L1
D 113478685 RAB32; ras-related protein Rab-32 K07918 RAB32; Ras-related protein Rab-32
D 113480729 RAB38; ras-related protein Rab-38 K07923 RAB38; Ras-related protein Rab-38
C Rab33
D 113480223 RAB33A; ras-related protein Rab-33A K07919 RAB33A; Ras-related protein Rab-33A
D 113479715 RAB33B; ras-related protein Rab-33B K07920 RAB33B; Ras-related protein Rab-33B
C Rab34/36
D 113486324 RAB36; ras-related protein Rab-36 isoform X1 K07922 RAB36; Ras-related protein Rab-36
C Rab39/42 [OT]
D 113485533 RAB39A; ras-related protein Rab-39A K07924 RAB39A; Ras-related protein Rab-39A
D 113480149 RAB39B; ras-related protein Rab-39B K07925 RAB39B; Ras-related protein Rab-39B
D 113488348 RAB42; ras-related protein Rab-42 K07925 RAB39B; Ras-related protein Rab-39B
C Rab40
D 113486921 RAB40B; ras-related protein Rab-40B K07928 RAB40; Ras-related protein Rab-40
D 113485822 RAB40C; ras-related protein Rab-40C K07928 RAB40; Ras-related protein Rab-40
C Rab45
D 113481102 CRACR2B; EF-hand calcium-binding domain-containing protein 4A isoform X1 K17199 RASEF; Ras and EF-hand domain-containing protein
D 113490159 RASEF; ras and EF-hand domain-containing protein K17199 RASEF; Ras and EF-hand domain-containing protein
D 113491131 CRACR2A; LOW QUALITY PROTEIN: EF-hand calcium-binding domain-containing protein 4B K17199 RASEF; Ras and EF-hand domain-containing protein
C Rab-like
D 113491288 rab-like protein 2A K07931 RABL2; Rab-like protein 2
C Others
B Ran Family
C Ran
D 113486002 RAN; GTP-binding nuclear protein Ran K07936 RAN; GTP-binding nuclear protein Ran
B Arf/Sar Family
C Arf [OT]
D 113476357 ARF1; ADP-ribosylation factor 1 K07937 ARF1_2; ADP-ribosylation factor 1/2
D 113485037 ARF4; ADP-ribosylation factor 4 K07939 ARF4; ADP-ribosylation factor 4
D 113480759 ARF6; ADP-ribosylation factor 6 K07941 ARF6; ADP-ribosylation factor 6
C Arl1/Arl5 [OT]
D 113487972 ARL1; ADP-ribosylation factor-like protein 1 isoform X1 K07942 ARL1; ADP-ribosylation factor-like protein 1
D 113482196 ARL5A; ADP-ribosylation factor-like protein 5A isoform X1 K07949 ARL5A; ADP-ribosylation factor-like protein 5A
D 113477119 ARL5B; ADP-ribosylation factor-like protein 5B K07950 ARL5B; ADP-ribosylation factor-like protein 5B
C Arl2/Arl3
D 113481408 ARL3; ADP-ribosylation factor-like protein 3 K07944 ARL3; ADP-ribosylation factor-like protein 3
D 113485275 ADP-ribosylation factor-like protein 3 isoform X1 K07944 ARL3; ADP-ribosylation factor-like protein 3
C Arl4/Arl7
D 113476755 ARL4A; ADP-ribosylation factor-like protein 4A K07945 ARL4; ADP-ribosylation factor-like protein 4
C Arl6
D 113478310 ARL6; ADP-ribosylation factor-like protein 6 isoform X1 K07951 ARL6; ADP-ribosylation factor-like protein 6
C Arp
D 113487435 ARFRP1; ADP-ribosylation factor-related protein 1 K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Sar
D 113481945 SAR1A; GTP-binding protein SAR1a K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D 113485466 SAR1B; GTP-binding protein SAR1b K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
C Arl8
D 113491233 ADP-ribosylation factor-like protein 8B-A K07955 ARL8; ADP-ribosylation factor-like protein 8
D 113488960 ARL8A; ADP-ribosylation factor-like protein 8A K07955 ARL8; ADP-ribosylation factor-like protein 8
D 113484812 ARL8B; ADP-ribosylation factor-like protein 8B K07955 ARL8; ADP-ribosylation factor-like protein 8
C Others
D 113479691 ARL9; ADP-ribosylation factor-like protein 9 K07957 ARL9; ADP-ribosylation factor-like protein 9
D 113485388 ARL10; ADP-ribosylation factor-like protein 10 K07958 ARL10; ADP-ribosylation factor-like protein 10
D 113485627 ARL11; ADP-ribosylation factor-like protein 11 K07959 ARL11; ADP-ribosylation factor-like protein 11
D 113476549 ARL13B; ADP-ribosylation factor-like protein 13B isoform X1 K07962 ARL13B; ADP-ribosylation factor-like protein 13B
D 113483372 ARL14; ADP-ribosylation factor-like protein 14 K17200 ARL14; ADP-ribosylation factor-like protein 14
D 113489733 ARL15; ADP-ribosylation factor-like protein 15 K17201 ARL15; ADP-ribosylation factor-like protein 15
D 113489538 TRIM23; E3 ubiquitin-protein ligase TRIM23 isoform X1 K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
B Unclassified
C 113479314 RABL3; rab-like protein 3 K07933 RABL3; Rab-like protein 3
C 113487208 IFT22; intraflagellar transport protein 22 homolog K07935 IFT22; intraflagellar transport protein 22
C 113483660 SRPRB; signal recognition particle receptor subunit beta K12272 SRPRB; signal recognition particle receptor subunit beta
C 113478036 GTPBP2; GTP-binding protein 2 K24888 GTPBP2; GTP-binding protein 2
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#Last updated: February 24, 2023