+F Repair protein KO
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DNA Repair and Recombination Proteins - Arcobacter ellisii
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D AELL_2155 ogt; O6-alkylguanine-DNA-alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AELL_1690 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E AELL_2785 ung; uracil-DNA glycosylase, family 1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E AELL_0811 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
E AELL_2084 putative Rad52/22 family double-strand break repair protein K10873 RAD52; DNA repair and recombination protein RAD52
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D AELL_2508 Nudix domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AELL_0947 putative ADP-ribose pyrophosphatase YjhB, Nudix family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D AELL_2155 ogt; O6-alkylguanine-DNA-alkyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AELL_1849 ada; O6-methylguanine-DNA methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D AELL_1690 phrB; deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D AELL_0760 deoxyribodipyrimidine photolyase-related protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E AELL_2785 ung; uracil-DNA glycosylase, family 1 K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E AELL_0923 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E AELL_0811 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E AELL_0967 xth; exodeoxyribonuclease III (exonuclease III) K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E AELL_2721 nfo; endonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E AELL_2751 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E AELL_1596 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E AELL_1101 uvrA; UvrABC nucleotide excision repair complex, subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E AELL_0810 uvrB; UvrABC nucleotide excision repair complex, subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E AELL_0934 uvrC; UvrABC nucleotide excision repair complex, subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E AELL_2574 UvrD/REP family helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AELL_0704 rep; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AELL_1596 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F AELL_2458 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F AELL_2457 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F AELL_1725 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F AELL_0827 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F AELL_0548 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E AELL_0616 mutS; DNA mismatch repair ATPase K03555 mutS; DNA mismatch repair protein MutS
E AELL_1674 mutS2; DNA mismatch binding protein, MutS2 family K07456 mutS2; DNA mismatch repair protein MutS2
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E AELL_0565 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E AELL_1157 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E AELL_1548 DEDDh 3'-5' exonuclease domain family protein K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E AELL_2757 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E AELL_0002 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E AELL_0387 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E AELL_1476 holB; DNA polymerase III, delta prime subunit K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E AELL_0648 dnaQ1; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AELL_0654 dnaQ2; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AELL_0998 dnaQ3; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AELL_1692 DEDDh 3'-5' exonuclease domain family protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AELL_0428 dnaX; DNA polymerase III, gamma and tau subunits K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E AELL_1596 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E AELL_2574 UvrD/REP family helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AELL_0704 rep; ATP-dependent DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AELL_0389 ssb; single-stranded DNA binding protein K03111 ssb; single-strand DNA-binding protein
E AELL_1324 hypothetical protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E AELL_2521 addA; AddAB recombination complex, helicase AddA K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E AELL_1146 helicase, RecD/TraA family (non-RecBCD) K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E AELL_2688 recA; recombinase K03553 recA; recombination protein RecA
E AELL_0892 ruvA; RuvABC resolvasome, subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E AELL_2171 ruvB; RuvABC resolvasome, subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E AELL_2853 ruvC; RuvABC resolvasome, subunit RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E AELL_1754 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E AELL_1361 SbcCD-like exonuclease, ATPase subunit K03546 sbcC; DNA repair protein SbcC/Rad50
E AELL_1360 SbcCD-like exonuclease, nuclease subunit K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E AELL_2688 recA; recombinase K03553 recA; recombination protein RecA
E AELL_1026 radA; DNA repair and recombination protein K04485 radA; DNA repair protein RadA/Sms
E AELL_2751 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E AELL_1580 recR; recombination protein K06187 recR; recombination protein RecR
E AELL_2399 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E AELL_0892 ruvA; RuvABC resolvasome, subunit RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E AELL_2171 ruvB; RuvABC resolvasome, subunit RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E AELL_2853 ruvC; RuvABC resolvasome, subunit RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E AELL_2563 addB; AddAB recombination complex, helicase AddB K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E AELL_1361 SbcCD-like exonuclease, ATPase subunit K03546 sbcC; DNA repair protein SbcC/Rad50
E AELL_1360 SbcCD-like exonuclease, nuclease subunit K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F AELL_2190 gyrA; DNA gyrase, subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F AELL_0003 gyrB; DNA gyrase, subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F AELL_2695 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F AELL_1263 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F AELL_2751 recJ; single-stranded DNA-specific exonuclease K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F AELL_1580 recR; recombination protein K06187 recR; recombination protein RecR
F AELL_1596 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F AELL_0443 recQ; ATP-dependent DNA helicase K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F AELL_1101 uvrA; UvrABC nucleotide excision repair complex, subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F AELL_0810 uvrB; UvrABC nucleotide excision repair complex, subunit UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D AELL_1863 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D AELL_2688 recA; recombinase K03553 recA; recombination protein RecA
D AELL_2399 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D AELL_0389 ssb; single-stranded DNA binding protein K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D AELL_2508 Nudix domain-containing protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AELL_0947 putative ADP-ribose pyrophosphatase YjhB, Nudix family K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AELL_0063 nrdA; aerobic ribonucleoside-diphosphate reductase Ia, B1 protein subunit NrdA K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AELL_0064 nrdB; aerobic ribonucleoside-diphosphate reductase Ia, B2 protein subunit NrdB K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
D AELL_2555 nrnA; nanoRNase / pAp phosphatase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024