+D Messenger RNA Biogenesis KO
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Prokaryotic Defense System - Acidithiobacillus ferrooxidans ATCC 53993
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ACRISPR-Cas system
B Universal Cas proteins
B Type I CRISPR-Cas system
C Type I signiture cas proteins
C Subtype I-A factors
C Subtype I-B factors
C Subtype I-C factors
C Subtype I-D factors
C Subtype I-E factors
C Subtype I-F factors
C Subtype I-U factors
B Type II CRISPR-Cas system
C Type II signiture cas proteins
C Subtype II-A factors
C Subtype II-B factors
B Type III CRISPR-Cas system
C Type III signiture cas proteins
C Subtype III-A factors
C Subtype III-B factors
C Subtype III-U factors
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ARestriction and modification system (R-M system)
B Type I R-M system
C Lferr_0226 type III restriction protein res subunit K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C Lferr_0832 EcoEI R domain protein K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C Lferr_0969 type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C Lferr_2012 type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C Lferr_2413 type I site-specific deoxyribonuclease, HsdR family K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]
C Lferr_0227 restriction modification system DNA specificity domain K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C Lferr_0835 restriction modification system DNA specificity domain K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C Lferr_0967 restriction modification system DNA specificity domain K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C Lferr_2009 restriction modification system DNA specificity domain K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C Lferr_2415 restriction modification system DNA specificity domain K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]
C Lferr_0228 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C Lferr_0833 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C Lferr_0964 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C Lferr_2003 type I restriction-modification system, M subunit K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
C Lferr_2418 N-6 DNA methylase K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]
B Type II R-M system
C Restriction endonucleases
C DNA methyltransferases
D Lferr_0139 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Lferr_1279 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
D Lferr_2793 DNA methylase N-4/N-6 domain protein K00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]
B Type III R-M system
C Lferr_2792 type III restriction protein res subunit K01156 res; type III restriction enzyme [EC:3.1.21.5]
B Type IV R-M system
C Lferr_1428 restriction endonuclease-like protein K07451 mcrA; 5-methylcytosine-specific restriction enzyme A [EC:3.1.21.-]
C Lferr_2388 restriction endonuclease K07448 mrr; restriction system protein
C Lferr_2785 restriction endonuclease K07448 mrr; restriction system protein
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AToxin-antitoxin system (TA system)
B Type I TA system
C Hok-Sok
C SymE-SymR
C Ldr-Rdl
C TisB-IstR
C Ibs-Sib
C ShoB-OhsC
C RalR-RalA
B Type II TA system
C MazF-MazE
D Lferr_2505 transcriptional modulator of MazE/toxin, MazF K07171 mazF; mRNA interferase MazF [EC:3.1.-.-]
D Lferr_2506 transcriptional regulator/antitoxin, MazE K07172 mazE; antitoxin MazE
D Lferr_2509 transcriptional regulator/antitoxin, MazE K07172 mazE; antitoxin MazE
C ChpB-ChpS
C YhaV-PrlF
D Lferr_1132 conserved hypothetical protein K19155 yhaV; toxin YhaV [EC:3.1.-.-]
D Lferr_1133 putative regulator PrlF K19156 prlF; antitoxin PrlF
C RelE/StbE-RelB/StbD
D Lferr_1012 addiction module toxin, RelE/StbE family K06218 relE; mRNA interferase RelE/StbE
D Lferr_1011 protein of unknown function DUF172 K18923 stbD; antitoxin StbD
C YafQ-dinJ
D Lferr_1299 addiction module antitoxin, RelB/DinJ family K07473 dinJ; DNA-damage-inducible protein J
C YoeB-YefM
D Lferr_0575 addiction module toxin, Txe/YoeB family K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D Lferr_0995 addiction module toxin, Txe/YoeB family K19158 yoeB; toxin YoeB [EC:3.1.-.-]
D Lferr_0994 prevent-host-death family protein K19159 yefM; antitoxin YefM
C HipA-HipB
C HicA-HicB
D Lferr_1423 protein of unknown function UPF0150 K18843 hicB; antitoxin HicB
C YafO-YafN
C PspC-PspB
C CcdB-CcdA
C ParE-ParD
C Doc-Phd
C HigB-HigA
D Lferr_0090 plasmid maintenance system killer K07334 higB-1; toxin HigB-1
D Lferr_0091 putative plasmid maintenance system antidote protein, XRE family K21498 higA-1; antitoxin HigA-1
C MqsR-MqsA
C VapC-VapB
D Lferr_0638 PilT protein domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D Lferr_1788 PilT protein domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D Lferr_2281 PilT protein domain protein K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D Lferr_2391 PIN (PilT N terminus) domain K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]
D Lferr_0637 SpoVT/AbrB domain protein K18829 mvpT; antitoxin VapB
D Lferr_1789 virulence-associated protein, putative K18829 mvpT; antitoxin VapB
D Lferr_2392 virulence-associated protein VapB-like protein K18829 mvpT; antitoxin VapB
D Lferr_0576 conserved hypothetical protein K28279 vapC22; ribonuclease VapC22 [EC:3.1.-.-]
D Lferr_0026 hypothetical protein K28280 vapB22; antitoxin VapB22
D Lferr_0577 prevent-host-death family protein K28280 vapB22; antitoxin VapB22
D Lferr_0088 conserved hypothetical protein K28275 vapC35S; ribonuclease VapC35/45/46/47 [EC:3.1.-.-]
D Lferr_0087 prevent-host-death family protein K28276 vapB35S; antitoxin VapB35/45/46/47
C PezT-PezA
C YobL-YobK
C YokI-YokJ
C YqcG-YqcF
C YxiD-YxxD
C FitB-FitA
D Lferr_1456 PilT protein domain protein K07062 fitB; toxin FitB [EC:3.1.-.-]
D Lferr_1455 plasmid stability protein-like protein K21495 fitA; antitoxin FitA
C BC_0920-BC_0921
C SpoIISA-SpoIISB
C Tse6-Tsi6
C Type II TA system related factors
D Lferr_0379 cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D Lferr_2192 cell shape determining protein, MreB/Mrl family K03569 mreB; rod shape-determining protein MreB and related proteins
D Lferr_1693 DNA topoisomerase IV, A subunit K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
D Lferr_1694 DNA topoisomerase (ATP-hydrolyzing) K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
D Lferr_0584 glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
B Type III TA system
C AbiQ system
B Type IV TA system
C YeeV-YeeU
C CptA-CptB
C AbiEii-AbiEi
B Type V TA system
C GhoT-GhoS
C Other GhoT/OrtT toxin family protein
B Type VI TA system
C SocB-SocA
B Type VII TA system
C Hha-TomB
C TglT-TakA
C HepT-MntA
B Type VIII TA system
C SdsR-RyeA
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ADNA phosphothiolation system
B Sulfur modification proteins
C Lferr_0188 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C Lferr_0822 cysteine desulfurase IscS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C Lferr_1225 cysteine desulfurase NifS K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C Lferr_1253 aminotransferase class V K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
B DNA phosphorothioation-dependent restriction proteins
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 19, 2025