+C	Cytokine	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Cytokines and Neuropeptides - Aptenodytes forsteri (emperor penguin)</h2>
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A<b>Cytokines</b>
B  Interleukins
C    103893227 interleukin-1 beta	K04519 IL1B; interleukin 1 beta 
C    103907343 interleukin-15-like	K05429 IL2; interleukin 2 
C    103904589 IL4; interleukin-4	K05430 IL4; interleukin 4 
C    103904588 interleukin-5	K05428 IL5; interleukin 5 
C    103901234 IL6; interleukin-6	K05405 IL6; interleukin 6 
C    103893328 interleukin-7	K05431 IL7; interleukin 7 
C    103893586 IL10; interleukin-10	K05443 IL10; interleukin 10 
C    103899051 IL12A; interleukin-12 subunit alpha	K05406 IL12A; interleukin 12A 
C    103904300 IL12B; interleukin-12 subunit beta	K05425 IL12B; interleukin 12B 
C    103908031 IL15; interleukin-15 isoform X1	K05433 IL15; interleukin 15 
C    103896654 IL16; pro-interleukin-16	K22628 IL16; interleukin 16 
C    103906899 IL17A; LOW QUALITY PROTEIN: interleukin-17A	K05489 IL17A; interleukin 17A 
C    103904307 IL17B; interleukin-17B	K05490 IL17B; interleukin 17B 
C    103906898 interleukin-17F	K05494 IL17F; interleukin 17F 
C    103895889 IL18; interleukin-18	K05482 IL18; interleukin 18 
C    103893686 interleukin-20	K22667 IL20; interleukin 20 
C    103893930 IL22; interleukin-22	K05445 IL22; interleukin 22 
C    109279288 IL26; interleukin-26	K05446 IL26; interleukin 26 
C    103908469 IL34; interleukin-34	K22633 IL34; interleukin 34 
B  Interferons
C    103894835 interferon epsilon	K05414 IFNA; interferon alpha 
C    109279355 interferon-like	K05415 IFNB; interferon beta 
C    103893931 IFNG; interferon gamma	K04687 IFNG; interferon gamma 
C    103903838 interferon lambda-3-like	K22669 IFNL2_3; interferon lambda 2/3 
B  CSF and other factors
C    103908277 CSF1; macrophage colony-stimulating factor 1	K05453 CSF1; macrophage colony-stimulating factor 1 
C    103893710 CSF3; granulocyte colony-stimulating factor	K05423 CSF3; granulocyte colony-stimulating factor 
C    103906046 somatotropin	K05438 GH; growth hormone 
C    103906265 THPO; thrombopoietin	K06854 THPO; thrombopoietin 
C    103896508 LIF; leukemia inhibitory factor	K05419 LIF; leukemia inhibitory factor 
C    103908516 CNTF; LOW QUALITY PROTEIN: ciliary neurotrophic factor	K05420 CNTF; ciliary neurotrophic factor 
B  Chemokines
C    103896520 C-C motif chemokine 4 homolog	K12964 CCL4; C-C motif chemokine 4 
C    103896521 C-C motif chemokine 4	K12964 CCL4; C-C motif chemokine 4 
C    103896522 C-C motif chemokine 5	K12499 CCL5; C-C motif chemokine 5 
C    103908437 CCL22; C-C motif chemokine 22	K21083 CCL17; C-C motif chemokine 17 
C    103908436 C-C motif chemokine 5	K21083 CCL17; C-C motif chemokine 17 
C    103905114 CCL20; C-C motif chemokine 20	K14625 CCL20; C-C motif chemokine 20 
C    103906340 C-C motif chemokine 21	K16062 CCL21; C-C motif chemokine 21 
C    103898933 C-X-C motif chemokine 5-like	K10030 IL8; interleukin 8 
C    103898934 interleukin-8 isoform X1	K10030 IL8; interleukin 8 
C    103898935 interleukin-8	K10030 IL8; interleukin 8 
C    103897829 CXCL12; stromal cell-derived factor 1	K10031 CXCL12; C-X-C motif chemokine 12 
C    109279724 C-X-C motif chemokine 2-like	K10032 CXCL13; C-X-C motif chemokine 13 
C    103906787 growth-regulated alpha protein	K10032 CXCL13; C-X-C motif chemokine 13 
C    103904427 CXCL14; C-X-C motif chemokine 14	K10033 CXCL14; C-X-C motif chemokine 14 
C    103908389 CX3CL1; fractalkine	K05508 CX3CL1; C-X3-C motif chemokine 1 
C    103907591 lymphotactin	K05507 XCL1; C motif chemokine 1 
C    103902341 PROK2; prokineticin-2	K24191 PROK; prokineticin 
C    103908272 PROK1; prokineticin-1	K24191 PROK; prokineticin 
C    103894393 CYTL1; cytokine-like protein 1	K25418 CYTL1; cytokine-like protein 1 
B  Tumor necrosis fators
C    109279298 TNFSF4; tumor necrosis factor ligand superfamily member 4	K05469 TNFSF4; tumor necrosis factor ligand superfamily member 4 
C    103905807 CD40LG; CD40 ligand	K03161 TNFSF5; tumor necrosis factor ligand superfamily member 5 
C    103894000 FASLG; tumor necrosis factor ligand superfamily member 6	K04389 TNFSF6; tumor necrosis factor ligand superfamily member 6 
C    103901374 TNFSF8; tumor necrosis factor ligand superfamily member 8	K05471 TNFSF8; tumor necrosis factor ligand superfamily member 8 
C    103906251 TNFSF10; tumor necrosis factor ligand superfamily member 10	K04721 TNFSF10; tumor necrosis factor ligand superfamily member 10 
C    103895905 TNFSF11; tumor necrosis factor ligand superfamily member 11	K05473 TNFSF11; tumor necrosis factor ligand superfamily member 11 
C    103896247 TNFSF13B; tumor necrosis factor ligand superfamily member 13B	K05476 TNFSF13B; tumor necrosis factor ligand superfamily member 13B 
C    103901373 TNFSF15; tumor necrosis factor ligand superfamily member 15	K05478 TNFSF15; tumor necrosis factor ligand superfamily member 15 
C    103906226 EDA; ectodysplasin-A	K05480 EDA; ectodysplasin-A 
B  Transforming growth factors (RSTK binding)
C    103896919 TGFB2; transforming growth factor beta-2	K13376 TGFB2; transforming growth factor beta-2 
C    103900124 TGFB3; transforming growth factor beta-3	K13377 TGFB3; transforming growth factor beta-3 
C    103904678 BMP1; bone morphogenetic protein 1	K05502 BMP1; bone morphogenetic protein 1 [EC:3.4.24.19] 
C    103897828 bone morphogenetic protein 7	K21283 BMP2; bone morphogenetic protein 2 
C    103901640 BMP2; bone morphogenetic protein 2	K21283 BMP2; bone morphogenetic protein 2 
C    103897080 LOW QUALITY PROTEIN: bone morphogenetic protein 2-like	K21283 BMP2; bone morphogenetic protein 2 
C    103898926 BMP3; LOW QUALITY PROTEIN: bone morphogenetic protein 3	K05496 BMP3; bone morphogenetic protein 3 
C    103907630 BMP4; bone morphogenetic protein 4	K04662 BMP4; bone morphogenetic protein 4 
C    103899291 BMP5; bone morphogenetic protein 5 isoform X1	K04663 BMP5; bone morphogenetic protein 5 
C    103898856 BMP6; bone morphogenetic protein 6	K16620 BMP6; bone morphogenetic protein 6 
C    103894631 BMP7; bone morphogenetic protein 7	K16621 BMP7; bone morphogenetic protein 7 
C    103903624 bone morphogenetic protein 8A	K16622 BMP8; bone morphogenetic protein 8 
C    103894414 BMP10; bone morphogenetic protein 10	K22670 BMP10; bone morphogenetic protein 10 
C    103903410 bone morphogenetic protein 15	K05498 BMP15; bone morphogenetic protein 15 
C    103899308 GDF1; embryonic growth/differentiation factor 1	K05495 GDF1; growth differentiation factor 1 
C    103897638 GDF2; growth/differentiation factor 2	K05503 GDF2; growth differentiation factor 2 
C    103902900 GDF5; growth/differentiation factor 5	K04664 GDF5; growth differentiation factor 5 
C    103899945 GDF7; growth/differentiation factor 7	K20013 GDF7; growth differentiation factor 7 
C    103897142 MSTN; growth/differentiation factor 8 isoform X1	K05497 MSTN; growth differentiation factor 8 
C    103904453 GDF9; growth/differentiation factor 9	K22673 GDF9; growth differentiation factor 9 
C    103897823 GDF10; growth/differentiation factor 10	K22674 GDF10; growth differentiation factor 10 
C    103899410 nodal homolog	K04666 NODAL; nodal 
C    103895358 INHA; inhibin alpha chain	K05500 INHA; inhibin, alpha 
C    103895262 INHBA; inhibin beta A chain	K04667 INHBA; inhibin beta A chain 
C    103895459 INHBB; LOW QUALITY PROTEIN: inhibin beta B chain	K22687 INHBB; inhibin beta B chain 
C    103901412 inhibin beta C chain	K22688 INHBC; inhibin beta C chain 
C    103903627 AMH; muellerian-inhibiting factor	K04665 AMH; anti-mullerian hormone 
C    103898886 left-right determination factor 2	K04668 LEFTY; left-right determination factor 
B  Growth factors (RTK binding)
C    103904978 PDGFA; platelet-derived growth factor subunit A	K04359 PDGFA; platelet-derived growth factor subunit A 
C    103907871 PDGFB; platelet-derived growth factor subunit B	K17386 PDGFB; platelet-derived growth factor subunit B 
C    103907872 platelet-derived growth factor subunit B	K17386 PDGFB; platelet-derived growth factor subunit B 
C    103902328 PDGFC; platelet-derived growth factor C	K05450 PDGFC_D; platelet derived growth factor C/D 
C    103895107 PDGFD; platelet-derived growth factor D isoform X1	K05450 PDGFC_D; platelet derived growth factor C/D 
C    103902722 VEGFA; vascular endothelial growth factor A	K05448 VEGFA; vascular endothelial growth factor A 
C    103896936 VEGFD; vascular endothelial growth factor D isoform X1	K05449 VEGFC_D; vascular endothelial growth factor C/D 
C    103893295 VEGFC; LOW QUALITY PROTEIN: vascular endothelial growth factor C	K05449 VEGFC_D; vascular endothelial growth factor C/D 
C    103900261 PGF; placenta growth factor	K16859 PGF; placenta growth factor 
C    103893547 NGF; beta-nerve growth factor	K02582 NGFB; nerve growth factor, beta 
C    103906570 NTF3; neurotrophin-3	K04356 NTF3; neurotrophin 3 
C    103906808 BDNF; brain-derived neurotrophic factor isoform X2	K04355 BDNF; brain-derived neurotrophic factor 
C    103903870 GDNF; glial cell line-derived neurotrophic factor isoform X1	K05452 GDNF; glial cell derived neurotrophic factor 
C    103900455 NRTN; neurturin	K25414 NRTN; neurturin 
C    103905573 ARTN; artemin	K25415 ARTN; artemin 
C    103904460 FGF1; fibroblast growth factor 1	K18496 FGF1; fibroblast growth factor 1 
C    103907355 FGF2; fibroblast growth factor 2	K18497 FGF2; fibroblast growth factor 2 
C    103896626 FGF7; fibroblast growth factor 7 isoform X1	K04358 FGF; fibroblast growth factor 
C    103899426 FGF22; fibroblast growth factor 22	K04358 FGF; fibroblast growth factor 
C    103897426 FGF20; fibroblast growth factor 20	K04358 FGF; fibroblast growth factor 
C    103897883 FGF8; fibroblast growth factor 8	K04358 FGF; fibroblast growth factor 
C    103904479 FGF18; fibroblast growth factor 18	K04358 FGF; fibroblast growth factor 
C    103904687 FGF17; fibroblast growth factor 17	K04358 FGF; fibroblast growth factor 
C    103904937 FGF3; fibroblast growth factor 3	K04358 FGF; fibroblast growth factor 
C    103898927 FGF5; fibroblast growth factor 5	K04358 FGF; fibroblast growth factor 
C    103898962 FGF9; fibroblast growth factor 9	K04358 FGF; fibroblast growth factor 
C    103906576 FGF6; fibroblast growth factor 6	K04358 FGF; fibroblast growth factor 
C    103895048 FGF10; fibroblast growth factor 10 isoform X1	K04358 FGF; fibroblast growth factor 
C    103901280 FGF13; fibroblast growth factor 13 isoform X1	K22413 FGF11_12_13; fibroblast growth factor 11/12/13 
C    103901453 FGF12; fibroblast growth factor 12	K22413 FGF11_12_13; fibroblast growth factor 11/12/13 
C    103906348 FGF14; fibroblast growth factor 14 isoform X1	K23920 FGF14; fibroblast growth factor 14 
C    103905112 FGF19; fibroblast growth factor 19	K22603 FGF19; fibroblast growth factor 19 
C    103906575 FGF23; fibroblast growth factor 23	K22428 FGF23; fibroblast growth factor 23 
C    103895138 NRG1; pro-neuregulin-1, membrane-bound isoform isoform X1	K05455 NRG1; neuregulin 1 
C    103899582 NRG2; pro-neuregulin-2, membrane-bound isoform	K05456 NRG2; neuregulin 2 
C    103898542 NRG3; pro-neuregulin-3, membrane-bound isoform	K05457 NRG3; neuregulin 3 
C    103898552 NRG4; pro-neuregulin-4, membrane-bound isoform	K05458 NRG4; neuregulin 4 
C    103906465 IGF1; insulin-like growth factor I	K05459 IGF1; insulin-like growth factor 1 
C    103906714 IGF2; insulin-like growth factor II	K13769 IGF2; insulin-like growth factor 2 
C    103904147 HGF; hepatocyte growth factor	K05460 HGF; hepatocyte growth factor 
C    103894243 EGF; pro-epidermal growth factor isoform X1	K04357 EGF; epidermal growth factor 
C    103898931 EREG; proepiregulin	K09784 EREG; epiregulin 
C    103898941 AREG; amphiregulin	K09782 AREG; amphiregulin 
C    103903306 KITLG; kit ligand	K05461 KITLG; KIT ligand 
C    103903073 EFNA5; ephrin-A5	K05462 EFNA; ephrin-A 
C    103905541 ephrin-A2-like	K05462 EFNA; ephrin-A 
C    103905542 ephrin-A3	K05462 EFNA; ephrin-A 
C    103905543 EFNA1; ephrin-A1	K05462 EFNA; ephrin-A 
C    103899409 ephrin-A2	K05462 EFNA; ephrin-A 
C    103904686 EFNB2; ephrin-B2	K05463 EFNB; ephrin-B 
C    103906153 EFNB1; ephrin-B1	K05463 EFNB; ephrin-B 
C    103896312 GAS6; growth arrest-specific protein 6	K05464 GAS6; growth arrest-specific 6 
C    103894854 ANGPT1; LOW QUALITY PROTEIN: angiopoietin-1	K05465 ANGPT1; angiopoietin 1 
C    103906625 ANGPT2; angiopoietin-2 isoform X1	K05466 ANGPT2; angiopoietin 2 
C    103901823 ANGPT4; angiopoietin-4	K05467 ANGPT4; angiopoietin 4 
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A<b>Neuropeptides</b>
B  Neuropeptides (GPCR binding)
C    103900971 AGT; angiotensinogen	K09821 AGT; angiotensinogen 
C    103906262 KNG1; kininogen-1	K03898 KNG; kininogen 
C    103904112 NTS; neurotensin/neuromedin N	K05235 NTS; neurotensin 
C    103896459 NMB; LOW QUALITY PROTEIN: neuromedin-B	K05223 NMB; neuromedin B 
C    103907946 CCK; cholecystokinin	K05226 CCK; cholecystokinin 
C    103894370 EDN1; endothelin-1	K16366 EDN1; endothelin-1 
C    103905097 endothelin-2	K16367 EDN2; endothelin-2 
C    103896203 GAL; galanin peptides isoform X1	K05244 GAL; galanin 
C    103898737 SPX; spexin	K25694 SPX; spexin 
C    109279277 MLN; promotilin	K05265 MLN; motilin 
C    103897436 NMU; neuromedin-U	K05249 NMU; neuromedin U 
C    103901190 NPVF; pro-FMRFamide-related neuropeptide VF	K25692 NPVF; pro-FMRFamide-related neuropeptide VF 
C    103897946 NPS; LOW QUALITY PROTEIN: neuropeptide S	K25691 NPS; neuropeptide S 
C    103901197 NPY; pro-neuropeptide Y	K05232 NPY; neuropeptide Y 
C    103902404 POMC; pro-opiomelanocortin	K05228 POMC; proopiomelanocortin 
C    103907226 PENK; proenkephalin-A	K18832 PENK; proenkephalin A 
C    103901814 PDYN; LOW QUALITY PROTEIN: proenkephalin-B	K15840 PDYN; proenkephalin B (prodynorphin) 
C    103902408 PNOC; prepronociceptin	K25696 PNOC; prepronociceptin 
C    103905376 QRFP; orexigenic neuropeptide QRFP	K25693 QRFP; orexigenic neuropeptide QRFP 
C    103908369 OXT; oxytocin-neurophysin 1	K05243 OXT; oxytocin-neurophysin 1 
C    103901465 SST; somatostatin	K05237 SST; somatostatin 
C    103907453 CORT; cortistatin	K05238 CORT; cortistatin 
C    103904964 TAC1; protachykinin-1	K05239 TAC1; tachykinin 1 
C    103894681 UTS2; urotensin-2	K05248 UTS2; urotensin 2 
C    103901456 UTS2B; urotensin-2B	K24267 UTS2B; urotensin-2B 
C    103908368 vasotocin-neurophysin VT	K05242 AVP; arginine vasopressin 
C    103907938 PRLH; prolactin-releasing peptide	K05269 PRH; Prolactin-releasing peptide 
C    103902234 HCRT; orexin	K05246 HCRT; hypocretin (orexin) neuropeptide 
C    103900171 CHGA; chromogranin-A	K19990 CHGA; chromogranin-A 
C    103901670 CHGB; secretogranin-1	K19991 CHGB; chromogranin-B 
C    103905099 SCG2; secretogranin-2	K25732 SCG2; secretogranin-2 
C    103896698 SCG3; secretogranin-3	K25733 SCG3; secretogranin-3 
C    103904352 SCG5; neuroendocrine protein 7B2 isoform X1	K25734 SCG5; neuroendocrine protein 7B2 
C    103893802 GNRH1; progonadoliberin-1	K05252 GNRH; gonadotropin-releasing hormone 
C    103902746 TRH; thyrotropin releasing hormone	K05253 TRH; thyrotropin-releasing hormone 
C    103898453 INSL5; insulin-like peptide INSL5	K22001 INSL5; insulin-like 5 
C    103906464 PMCH; pro-MCH	K05229 PMCH; pro-melanin-concentrating hormone 
C    103906747 CALCB; calcitonin gene-related peptide 2 isoform X1	K12332 CALC; calcitonin 
C    103898682 IAPP; islet amyloid polypeptide	K08039 IAPP; islet amyloid polypeptide 
C    103896900 CRH; corticoliberin	K05256 CRH; corticotropin-releasing hormone 
C    103908110 UCN3; urocortin-3	K05257 UCN2_3; urocortin 2/3 
C    103905972 GIP; gastric inhibitory polypeptide	K05258 GIP; gastric inhibitory polypeptide 
C    103895348 GCG; glucagon	K05259 GCG; glucagon 
C    103906785 PTH; parathyroid hormone	K05261 PTH; parathyroid hormone 
C    103900694 VIP; VIP peptides	K05264 VIP; vasoactive intestinal peptide 
C    103906564 PTHLH; parathyroid hormone-related protein	K22608 PTHLH; parathyroid hormone-related hormone 
C    103901116 CGA; glycoprotein hormones alpha chain	K08522 CGA; glycoprotein hormones alpha chain 
C    103906803 FSHB; follitropin subunit beta	K05250 FSHB; follitropin subunit beta 
C    103893548 TSHB; thyrotropin subunit beta	K05251 TSHB; thyrotropin subunit beta 
C    103894064 GPHB5; glycoprotein hormone beta-5	K25484 GPHB5; glycoprotein hormone beta-5 
B  Neuropeptides (Unclassified)
C    103907442 NPPA; natriuretic peptides A	K12334 NPPA; natriuretic peptide A 
C    103907439 NPPC; C-type natriuretic peptide	K12336 NPPC; natriuretic peptide C 
C    103904966 NXPH1; neurexophilin-1	K16656 NXPH1; neurexophilin-1 
C    103899467 NXPH2; neurexophilin-2	K16657 NXPH2; neurexophilin-2 
C    103905975 NXPH3; neurexophilin-3	K16658 NXPH3; neurexophilin-3 
C    103901410 NXPH4; neurexophilin-4	K25711 NXPH4; neurexophilin-4 
C    103906715 INS; insulin	K04526 INS; insulin 
C    103903816 PRL; prolactin	K05439 PRL; prolactin 
C    103908461 AGRP; agouti-related protein	K05231 AGRP; agouti related protein 
C    103893220 DBI; acyl-CoA-binding protein	K08762 DBI; diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) 
C    103908479 CBLN2; cerebellin-2	K24235 CBLN; cerebellin 
C    103903128 ADIPOQ; adiponectin	K07296 ADIPOQ; adiponectin 
C    103907008 NAMPT; nicotinamide phosphoribosyltransferase	K03462 NAMPT; nicotinamide phosphoribosyltransferase [EC:2.4.2.12] 
C    103906742 NUCB2; nucleobindin-2	K20371 NUCB; nucleobindin 
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#Last updated: March 5, 2024