+D Chaperone KO
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Chaperones and Folding Catalysts - Aphidius gifuensis
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AHeat shock proteins
B HSP110
C 122861168 hypoxia up-regulated protein 1 K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C 122848379 caseinolytic peptidase B protein homolog K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
C 122859547 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1 K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
B HSP90
C 122852920 heat shock protein 83 K04079 HSP90A; molecular chaperone HtpG
C 122856608 heat shock protein 83-like K04079 HSP90A; molecular chaperone HtpG
C 122851856 endoplasmin homolog K09487 HSP90B; heat shock protein 90kDa beta
C 122854248 endoplasmin homolog K09487 HSP90B; heat shock protein 90kDa beta
C 122851721 heat shock protein 75 kDa, mitochondrial K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C 122849001 heat shock protein 70 A1-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 122851919 heat shock protein 70 A1-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 122853748 heat shock protein 70 A1-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 122854655 heat shock 70 kDa protein-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 122857448 heat shock 70 kDa protein cognate 4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 122857777 heat shock protein 68-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 122859282 heat shock protein 70 B2-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 122860652 heat shock 70 kDa protein II-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 122848369 heat shock 70 kDa protein 4 isoform X1 K09489 HSPA4; heat shock 70kDa protein 4
C 122856793 endoplasmic reticulum chaperone BiP K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C 122859174 heat shock 70 kDa protein 14-like K28183 HSPA14; heat shock 70 kDa protein 14
C 122852651 heat shock 70 kDa protein cognate 5-like K04043 dnaK; molecular chaperone DnaK
C 122852652 heat shock 70 kDa protein cognate 5-like K04043 dnaK; molecular chaperone DnaK
C 122855499 heat shock 70 kDa protein cognate 5-like K04043 dnaK; molecular chaperone DnaK
C 122855501 heat shock 70 kDa protein cognate 5-like K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C 122859053 T-complex protein 1 subunit alpha-like K09493 CCT1; T-complex protein 1 subunit alpha
C 122859104 T-complex protein 1 subunit alpha-like K09493 CCT1; T-complex protein 1 subunit alpha
C 122847509 T-complex protein 1 subunit beta K09494 CCT2; T-complex protein 1 subunit beta
C 122858285 T-complex protein 1 subunit gamma isoform X1 K09495 CCT3; T-complex protein 1 subunit gamma
C 122856587 T-complex protein 1 subunit delta K09496 CCT4; T-complex protein 1 subunit delta
C 122849671 T-complex protein 1 subunit epsilon K09497 CCT5; T-complex protein 1 subunit epsilon
C 122848394 T-complex protein 1 subunit zeta K09498 CCT6; T-complex protein 1 subunit zeta
C 122858902 T-complex protein 1 subunit eta K09499 CCT7; T-complex protein 1 subunit eta
C 122855917 T-complex protein 1 subunit theta K09500 CCT8; T-complex protein 1 subunit theta
C 122848387 heat shock protein 60A K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C 122848598 protein tumorous imaginal discs, mitochondrial-like isoform X1 K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 122856264 uncharacterized protein LOC122856264 K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 122857194 chaperone protein DnaJ-like K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 122852043 dnaJ homolog subfamily C member 21 isoform X1 K09506 DNAJA5; DnaJ homolog subfamily A member 5
C 122859537 dnaJ protein homolog 1 K09507 DNAJB1; DnaJ homolog subfamily B member 1
C 122853321 dnaJ homolog subfamily B member 6 isoform X1 K09512 DNAJB6; DnaJ homolog subfamily B member 6
C 122855628 dnaJ homolog subfamily C member 30, mitochondrial-like K09515 DNAJB9; DnaJ homolog subfamily B member 9
C 122853957 dnaJ homolog shv K09517 DNAJB11; DnaJ homolog subfamily B member 11
C 122854254 dnaJ homolog subfamily B member 12 K09518 DNAJB12; DnaJ homolog subfamily B member 12
C 122849341 dnaJ homolog subfamily B member 13-like K09519 DNAJB13; DnaJ homolog subfamily B member 13
C 122848105 dnaJ homolog subfamily C member 1-like K09521 DNAJC1; DnaJ homolog subfamily C member 1
C 122858217 dnaJ homolog subfamily C member 2 K09522 DNAJC2; DnaJ homolog subfamily C member 2
C 122852337 dnaJ homolog subfamily C member 3 K09523 DNAJC3; DnaJ homolog subfamily C member 3
C 122851313 dnaJ homolog subfamily C member 5 isoform X1 K09525 DNAJC5; DnaJ homolog subfamily C member 5
C 122858895 dnaJ homolog subfamily C member 8 K09528 DNAJC8; DnaJ homolog subfamily C member 8
C 122858782 dnaJ homolog subfamily C member 9 K09529 DNAJC9; DnaJ homolog subfamily C member 9
C 122861217 dnaJ homolog subfamily C member 10-like K09530 DNAJC10; DnaJ homolog subfamily C member 10 [EC:1.8.4.-]
C 122858678 dnaJ homolog subfamily C member 11 K09531 DNAJC11; DnaJ homolog subfamily C member 11
C 122854777 J domain-containing protein K09532 DNAJC12; DnaJ homolog subfamily C member 12
C 122851267 dnaJ homolog subfamily C member 13 isoform X1 K09533 DNAJC13; DnaJ homolog subfamily C member 13
C 122852515 dnaJ homolog subfamily C member 16-like K09536 DNAJC16; DnaJ homolog subfamily C member 16
C 122861225 dnaJ homolog subfamily C member 17 K09537 DNAJC17; DnaJ homolog subfamily C member 17
C 122852846 mitochondrial import inner membrane translocase subunit TIM14-like K09539 DNAJC19; DnaJ homolog subfamily C member 19
C 122857700 mitochondrial import inner membrane translocase subunit TIM14-like K09539 DNAJC19; DnaJ homolog subfamily C member 19
C 122856848 dnaJ homolog subfamily C member 22 K19370 DNAJC22; DnaJ homolog subfamily C member 22
C 122857278 translocation protein SEC63 homolog K09540 SEC63; translocation protein SEC63
C 122857392 dnaJ homolog subfamily C member 28 K19373 DNAJC28; DnaJ homolog subfamily C member 28
C 122852687 iron-sulfur cluster co-chaperone protein HscB K04082 hscB; molecular chaperone HscB
B HSP33
B HSP24
C 122848792 grpE protein homolog 1, mitochondrial K03687 GRPE; molecular chaperone GrpE
B HSP20
C 122852907 protein lethal(2)essential for life-like K09542 CRYAB; crystallin, alpha B
C 122857674 alpha-crystallin B chain-like K09542 CRYAB; crystallin, alpha B
C 122857677 protein lethal(2)essential for life-like K09542 CRYAB; crystallin, alpha B
C 122857678 protein lethal(2)essential for life-like K09542 CRYAB; crystallin, alpha B
C 122858182 protein lethal(2)essential for life-like K09542 CRYAB; crystallin, alpha B
C 122855346 dnaJ homolog subfamily A member 1 K09545 HSPB6; heat shock protein beta-6
B HSP15
B HSP10
C 122848466 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
B GimC
C 122852312 prefoldin subunit 1 K09548 PFDN1; prefoldin subunit 1
C 122858187 prefoldin subunit 2 K09549 PFDN2; prefoldin subunit 2
C 122850304 prefoldin subunit 4 K09550 PFDN4; prefoldin subunit 4
C 122858992 prefoldin subunit 5 K04797 pfdA; prefoldin alpha subunit
C 122860185 prefoldin subunit 6 K04798 pfdB; prefoldin beta subunit
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AOther chaperones and cochaperones
B Calnexin / calreticulin
C 122855485 calnexin K08054 CANX; calnexin
C 122858816 calreticulin K08057 CALR; calreticulin
B DegP / HtrA
C 122854409 serine protease HTRA2, mitochondrial isoform X1 K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
B AAA proteases
C 122857031 paraplegin K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
C 122857025 AFG3-like protein 2 K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C 122851830 stress-induced-phosphoprotein 1 K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
C 122851586 hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
B BAG
C 122850190 BAG family molecular chaperone regulator 2 K09556 BAG2; BCL2-associated athanogene 2
B Others
C 122859449 putative protein FAM10A4 K09560 ST13; suppressor of tumorigenicity protein 13
C 122850164 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 122858988 hsp70-binding protein 1-like K09562 HSPBP1; hsp70-interacting protein
C 122855010 HSPB1-associated protein 1 isoform X1 K19375 HSPBAP1; HSPB1-associated protein 1
C 122848637 protein OPI10 homolog K23327 HIKESHI; protein Hikeshi
C 122852422 cysteine and histidine-rich domain-containing protein K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C 122851580 prolyl 3-hydroxylase 2-like K22459 P3H2; procollagen-proline 3-dioxygenase 2 [EC:1.14.11.7]
C 122852699 methyltransferase-like protein 23 K23151 METTL23; methyltransferase-like protein 23 [EC:2.1.1.-]
C 122859045 protein unc-45 homolog B K21991 UNC45; protein unc-45
C 122857816 protein canopy 4 K22816 CNPY3_4; protein canopy 3/4
C 122857151 torsin-1A-like K22990 TOR1; torsin-1
C 122857177 torsin-1A-like K22990 TOR1; torsin-1
C 122859721 SPARC K24262 SPARC; secreted protein acidic and rich in cysteine
C 122857666 small glutamine-rich tetratricopeptide repeat-containing protein alpha-like K16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha
C 122851323 tetratricopeptide repeat protein 1 K24926 TTC1; tetratricopeptide repeat protein 1
C 122849727 DNA polymerase interacting tetratricopeptide repeat-containing, protein of 47 kDa-like K24927 TTC4; tetratricopeptide repeat protein 4
C 122849809 LOW QUALITY PROTEIN: PAT complex subunit CCDC47 K24962 CCDC47; PAT complex subunit CCDC47
C 122858543 PAT complex subunit Asterix K24963 WDR83OS; PAT complex subunit Asterix
C 122848518 LDLR chaperone boca isoform X1 K25366 MESD; LRP chaperone MESD
C 122861022 activator of 90 kDa heat shock protein ATPase homolog 1 K26216 AHSA1; activator of Hsp90 ATPase protein 1
C 122853069 novel acetylcholine receptor chaperone K26241 NACHO; novel acetylcholine receptor chaperone
C 122849795 huntingtin-interacting protein K K28128 HYPK; huntingtin-interacting protein K
C 122854430 viral IAP-associated factor homolog K28206 PDCL; phosducin-like protein
C 122854624 phosducin-like protein K28206 PDCL; phosducin-like protein
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AIntramolecular chaperones
B Subtilisin family
C 122861192 membrane-bound transcription factor site-1 protease K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C 122858476 furin-like protease 1 isoform X1 K01349 FURIN; furin [EC:3.4.21.75]
C 122854046 neuroendocrine convertase 1-like K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 122853164 neuroendocrine convertase 2 K01360 PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
C 122860292 furin-like protease 2 isoform X1 K08654 PCSK5; proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]
C 122860717 tripeptidyl-peptidase 2 isoform X1 K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C 122858578 procathepsin L-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 122858581 cathepsin L-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
C 122856252 trypsin alpha-like K01327 ELANE; leukocyte elastase [EC:3.4.21.37]
B Others
C 122852035 beta-hexosaminidase subunit beta-like K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 122852036 beta-hexosaminidase subunit beta-like K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 122858312 chitooligosaccharidolytic beta-N-acetylglucosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 122860797 chitooligosaccharidolytic beta-N-acetylglucosaminidase-like K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 122860798 chitooligosaccharidolytic beta-N-acetylglucosaminidase-like K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
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AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D 122850182 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 122853185 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 122858577 peptidyl-prolyl cis-trans isomerase D K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
D 122860166 peptidyl-prolyl cis-trans isomerase E K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D 122854820 peptidyl-prolyl cis-trans isomerase-like K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 122856934 peptidyl-prolyl cis-trans isomerase-like K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 122851831 peptidyl-prolyl cis-trans isomerase cyp11-like K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D 122857349 peptidyl-prolyl cis-trans isomerase H K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D 122856886 peptidyl-prolyl cis-trans isomerase-like 1 K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D 122857223 RING-type E3 ubiquitin-protein ligase PPIL2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D 122849212 peptidyl-prolyl cis-trans isomerase-like 3 K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D 122852555 peptidyl-prolyl cis-trans isomerase sig-7 K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D 122860855 peptidylprolyl isomerase domain and WD repeat-containing protein 1 isoform X1 K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D 122851161 spliceosome-associated protein CWC27 homolog K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 122852945 E3 SUMO-protein ligase RanBP2-like K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C FKBP
D 122851233 peptidyl-prolyl cis-trans isomerase FKBP1B K09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]
D 122851248 peptidyl-prolyl cis-trans isomerase FKBP4-like K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 122860515 FK506-binding protein 59-like isoform X1 K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 122855392 inactive peptidyl-prolyl cis-trans isomerase FKBP6 K09572 FKBP6; FK506-binding protein 6 [EC:5.2.1.8]
D 122849293 peptidyl-prolyl cis-trans isomerase FKBP8 K09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]
D 122860329 FK506-binding protein 2 isoform X1 K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
C Parvulin
D 122855399 putative peptidyl-prolyl cis-trans isomerase dodo K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D 122854266 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C 122852673 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 122860541 thioredoxin-like K03671 TXN; thioredoxin
C 122849922 uncharacterized protein LOC122849922 K03676 grxC; glutaredoxin 3
C 122849924 glutaredoxin-C3-like isoform X1 K03676 grxC; glutaredoxin 3
C 122860622 glutaredoxin-related protein 5, mitochondrial K07390 grxD; monothiol glutaredoxin
C 122853084 protein disulfide-isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 122854004 protein disulfide-isomerase-like K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 122852656 protein disulfide-isomerase A3-like K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C 122852657 LOW QUALITY PROTEIN: protein disulfide-isomerase A3-like K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C 122853253 protein disulfide-isomerase A6 homolog K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 122852342 thioredoxin domain-containing protein 5 homolog K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C 122860806 protein disulfide-isomerase TMX3 K09585 TMX3; protein disulfide-isomerase [EC:5.3.4.1]
C 122852933 cysteine-rich with EGF-like domain protein 2 K24335 CRELD; protein disulfide-isomerase [EC:5.3.4.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: September 25, 2025