+F Repair protein KO
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DNA Repair and Recombination Proteins - Adlercreutzia hattorii
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D ADCFC_15070 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E ADCFC_11310 endonuclease III K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E ADCFC_11440 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D ADCFC_15480 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ADCFC_12890 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D ADCFC_15070 methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E ADCFC_08000 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E ADCFC_11310 endonuclease III K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E ADCFC_11440 hypothetical protein K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E ADCFC_23200 exoA; exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E ADCFC_07150 nfo_1; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E ADCFC_22680 nfo_2; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
D RecJ
E ADCFC_08200 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E ADCFC_17340 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E ADCFC_10680 DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E ADCFC_14240 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E ADCFC_23230 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E ADCFC_17470 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E ADCFC_13730 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E ADCFC_06740 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_08380 DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_19170 helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_21120 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_22000 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_10680 DNA polymerase K02335 polA; DNA polymerase I [EC:2.7.7.7]
E ADCFC_17340 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F ADCFC_03990 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F ADCFC_04000 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F ADCFC_07850 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F ADCFC_12460 hypothetical protein K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F ADCFC_11450 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E ADCFC_13490 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E ADCFC_13480 hypothetical protein K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E ADCFC_17700 hypothetical protein K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E ADCFC_15940 dnaE; DNA-directed DNA polymerase K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E ADCFC_01190 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E ADCFC_12500 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E ADCFC_10160 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E ADCFC_04830 hypothetical protein K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E ADCFC_17340 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E ADCFC_06740 DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_08380 DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_19170 helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_21120 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_22000 hypothetical protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E ADCFC_01410 hypothetical protein K03111 ssb; single-strand DNA-binding protein
E ADCFC_19990 hypothetical protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E ADCFC_12780 recA; protein RecA K03553 recA; recombination protein RecA
E ADCFC_09930 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E ADCFC_09940 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E ADCFC_09920 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E ADCFC_11580 hypothetical protein K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E ADCFC_01450 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E ADCFC_12780 recA; protein RecA K03553 recA; recombination protein RecA
E ADCFC_01180 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E ADCFC_06080 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E ADCFC_02650 hypothetical protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E ADCFC_14980 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E ADCFC_19910 dihydroorotate dehydrogenase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E ADCFC_23330 ATPase AAA K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E ADCFC_24270 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E ADCFC_08200 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E ADCFC_12670 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E ADCFC_04850 recR; recombination protein RecR K06187 recR; recombination protein RecR
E ADCFC_17450 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E ADCFC_09930 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E ADCFC_09940 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E ADCFC_09920 crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E ADCFC_14120 hypothetical protein K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D Other HR factor
D Archaeal homologous recombinant proteins
E ADCFC_01450 exonuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E ADCFC_24230 hypothetical protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F ADCFC_01160 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F ADCFC_01170 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F ADCFC_10110 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F ADCFC_08200 hypothetical protein K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F ADCFC_12670 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F ADCFC_04850 recR; recombination protein RecR K06187 recR; recombination protein RecR
F ADCFC_17340 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F ADCFC_18460 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F ADCFC_14240 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F ADCFC_23230 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F ADCFC_17470 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D ADCFC_05620 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D ADCFC_13390 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D ADCFC_14200 DNA methylase K03502 umuC; DNA polymerase V
C Other SOS response factors
D ADCFC_12780 recA; protein RecA K03553 recA; recombination protein RecA
D ADCFC_12870 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D ADCFC_13560 hypothetical protein K01356 lexA; repressor LexA [EC:3.4.21.88]
D ADCFC_17450 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D ADCFC_01410 hypothetical protein K03111 ssb; single-strand DNA-binding protein
D ADCFC_12790 hypothetical protein K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D ADCFC_01360 DNA polymerase III subunit epsilon K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D ADCFC_19080 lhr; DEAD/DEAH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D ADCFC_15480 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D ADCFC_12890 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
D ADCFC_13770 phosphoesterase RecJ-like protein K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024