+F Repair protein KO
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DNA Repair and Recombination Proteins - Azonexus hydrophilus
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D AADV58_05200 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AADV58_03025 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E AADV58_06525 uracil-DNA glycosylase family protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E AADV58_01175 mutY; (GenBank) A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E AADV58_13240 nth; (GenBank) endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C SOSS complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D AADV58_04000 Nudix family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AADV58_04945 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AADV58_14205 dut; (GenBank) dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D AADV58_05200 methylated-DNA--[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D AADV58_03025 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D AADV58_13170 cryptochrome/photolyase family protein K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
C BER (base exicision repair)
D DNA glycosylases
E AADV58_06525 uracil-DNA glycosylase family protein K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E AADV58_10435 uracil-DNA glycosylase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E AADV58_05930 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E AADV58_01175 mutY; (GenBank) A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E AADV58_03890 mutM; (GenBank) bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E AADV58_13240 nth; (GenBank) endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E AADV58_00920 exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
E AADV58_16030 xth; (GenBank) exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E AADV58_11820 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E AADV58_11075 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E AADV58_00655 polA; (GenBank) DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E AADV58_15975 uvrA; (GenBank) excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
E AADV58_09580 uvrB; (GenBank) excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
E AADV58_09795 uvrC; (GenBank) excinuclease ABC subunit UvrC K03703 uvrC; excinuclease ABC subunit C
E AADV58_05235 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AADV58_17710 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AADV58_00655 polA; (GenBank) DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E AADV58_11075 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F AADV58_16625 rpoB; (GenBank) DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F AADV58_16620 rpoC; (GenBank) DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F AADV58_16460 rpoA; (GenBank) DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F AADV58_03260 rpoZ; (GenBank) DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F AADV58_10510 mfd; (GenBank) transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E AADV58_09440 mutS; (GenBank) DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E AADV58_07025 mutL; (GenBank) DNA mismatch repair endonuclease MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E AADV58_06835 xseA; (GenBank) exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E AADV58_13805 xseB; (GenBank) exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E AADV58_04270 dnaE; (GenBank) DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E AADV58_01700 dnaN; (GenBank) DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E AADV58_13920 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E AADV58_05215 holA; (GenBank) DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E AADV58_10060 holB; (GenBank) DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E AADV58_09245 exonuclease domain-containing protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AADV58_10820 dnaQ; (GenBank) DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AADV58_12365 hypothetical protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AADV58_12380 exonuclease domain-containing protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E AADV58_05795 dnaX; (GenBank) DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E AADV58_11075 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E AADV58_05235 UvrD-helicase domain-containing protein K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AADV58_17710 ATP-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E AADV58_15960 ssb; (GenBank) single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E AADV58_17280 ssb; (GenBank) single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E AADV58_18505 vsr; (GenBank) DNA mismatch endonuclease Vsr K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E AADV58_01940 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA
E AADV58_02280 ruvA; (GenBank) Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E AADV58_02290 ruvB; (GenBank) Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E AADV58_02275 ruvC; (GenBank) crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E AADV58_01480 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E AADV58_13020 priB; (GenBank) primosomal replication protein N K02686 priB; primosomal replication protein N
E AADV58_09355 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E AADV58_09360 sbcD; (GenBank) exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E AADV58_01940 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA
E AADV58_09490 radA; (GenBank) DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E AADV58_17395 radA; (GenBank) DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E AADV58_11395 RNA-binding domain-containing protein K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E AADV58_16410 recG; (GenBank) ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E AADV58_17320 DEAD/DEAH box helicase K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E AADV58_11820 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E AADV58_09720 recO; (GenBank) DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E AADV58_05805 recR; (GenBank) recombination mediator RecR K06187 recR; recombination protein RecR
E AADV58_14425 recN; (GenBank) DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E AADV58_03175 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E AADV58_18020 recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E AADV58_02280 ruvA; (GenBank) Holliday junction branch migration protein RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E AADV58_02290 ruvB; (GenBank) Holliday junction branch migration DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E AADV58_02275 ruvC; (GenBank) crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
E AADV58_08975 cas1; (GenBank) type II CRISPR-associated endonuclease Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
E AADV58_09355 AAA family ATPase K03546 sbcC; DNA repair protein SbcC/Rad50
E AADV58_09360 sbcD; (GenBank) exonuclease subunit SbcD K03547 sbcD; DNA repair protein SbcD/Mre11
E AADV58_02230 helicase HerA-like domain-containing protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F AADV58_12965 gyrA; (GenBank) DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F AADV58_01695 gyrB; (GenBank) DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F AADV58_11585 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F AADV58_15740 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
F AADV58_17380 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F AADV58_11820 recJ; (GenBank) single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F AADV58_09720 recO; (GenBank) DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F AADV58_05805 recR; (GenBank) recombination mediator RecR K06187 recR; recombination protein RecR
F AADV58_11075 ligA; (GenBank) NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F AADV58_16120 Fis family transcriptional regulator K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F AADV58_08515 integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F AADV58_12910 integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F AADV58_14510 recQ; (GenBank) DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F AADV58_15975 uvrA; (GenBank) excinuclease ABC subunit UvrA K03701 uvrA; excinuclease ABC subunit A
F AADV58_09580 uvrB; (GenBank) excinuclease ABC subunit UvrB K03702 uvrB; excinuclease ABC subunit B
F AADV58_08530 H-NS histone family protein K03746 hns; DNA-binding protein H-NS
F AADV58_08615 H-NS histone family protein K03746 hns; DNA-binding protein H-NS
F AADV58_16925 H-NS histone family protein K03746 hns; DNA-binding protein H-NS
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D AADV58_12500 dinB; (GenBank) DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D AADV58_01940 recA; (GenBank) recombinase RecA K03553 recA; recombination protein RecA
D AADV58_09230 lexA; (GenBank) transcriptional repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D AADV58_14425 recN; (GenBank) DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D AADV58_09235 imuA; (GenBank) translesion DNA synthesis-associated protein ImuA K14160 imuA; protein ImuA
D AADV58_09240 DNA polymerase Y family protein K14161 imuB; protein ImuB
D AADV58_10630 error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D AADV58_15960 ssb; (GenBank) single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D AADV58_17280 ssb; (GenBank) single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D AADV58_16095 dinD; (GenBank) DNA damage-inducible protein D K14623 dinD; DNA-damage-inducible protein D
D AADV58_01945 recX; (GenBank) recombination regulator RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D AADV58_03100 UvrD-helicase domain-containing protein K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D AADV58_10700 ATP-dependent DNA helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D AADV58_04000 Nudix family hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AADV58_04945 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D AADV58_14205 dut; (GenBank) dUTP diphosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D AADV58_09275 ribonucleoside-diphosphate reductase subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AADV58_13695 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AADV58_17740 adenosylcobalamin-dependent ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D AADV58_09290 ribonucleotide-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 23, 2026