+D	Messenger RNA Biogenesis	KO
#<h2><a href="/kegg/brite.html"><img src="/Fig/bget/kegg3.gif" align="middle" border=0></a>&nbsp; Prokaryotic Defense System - Actinobacillus indolicus</h2>
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A<b>CRISPR-Cas system</b>
B  Universal Cas proteins
C    EXH44_01730 cas1; type II CRISPR-associated endonuclease Cas1	K15342 cas1; CRISP-associated protein Cas1 
C    EXH44_01725 cas2; CRISPR-associated endonuclease Cas2	K09951 cas2; CRISPR-associated protein Cas2 
B  Type I CRISPR-Cas system
C    Type I signiture cas proteins
C    Subtype I-A factors
C    Subtype I-B factors
C    Subtype I-C factors
C    Subtype I-D factors
C    Subtype I-E factors
C    Subtype I-F factors
C    Subtype I-U factors
B  Type II CRISPR-Cas system
C    Type II signiture cas proteins
D      EXH44_01735 cas9; type II CRISPR RNA-guided endonuclease Cas9	K09952 csn1; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-] 
C    Subtype II-A factors
C    Subtype II-B factors
B  Type III CRISPR-Cas system
C    Type III signiture cas proteins
C    Subtype III-A factors
C    Subtype III-B factors
C    Subtype III-U factors
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A<b>Restriction and modification system (R-M system)</b>
B  Type I R-M system
C    EXH44_00185 type I restriction endonuclease subunit R	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    EXH44_10060 type I restriction endonuclease subunit R	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    EXH44_10415 type I restriction endonuclease subunit R	K01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3] 
C    EXH44_00175 hypothetical protein	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    EXH44_10045 restriction endonuclease subunit S	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    EXH44_10405 restriction endonuclease subunit S	K01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3] 
C    EXH44_10040 type I restriction-modification system subunit M	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
C    EXH44_10400 SAM-dependent DNA methyltransferase	K03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72] 
B  Type II R-M system
C    Restriction endonucleases
C    DNA methyltransferases
D      EXH44_02695 Dam family site-specific DNA-(adenine-N6)-methyltransferase	K06223 dam; DNA adenine methylase [EC:2.1.1.72] 
B  Type III R-M system
B  Type IV R-M system
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A<b>Toxin-antitoxin system (TA system)</b>
B  Type I TA system
C    Hok-Sok
C    SymE-SymR
C    Ldr-Rdl
C    TisB-IstR
C    Ibs-Sib
C    ShoB-OhsC
C    RalR-RalA
B  Type II TA system
C    MazF-MazE
C    ChpB-ChpS
C    YhaV-PrlF
C    RelE/StbE-RelB/StbD
D      EXH44_00075 type II toxin-antitoxin system RelE/ParE family toxin	K06218 relE; mRNA interferase RelE/StbE 
D      EXH44_10950 type II toxin-antitoxin system RelE/ParE family toxin	K06218 relE; mRNA interferase RelE/StbE 
D      EXH44_00080 ribbon-helix-helix domain-containing protein	K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB 
D      EXH44_10955 ribbon-helix-helix domain-containing protein	K18918 relB; RHH-type transcriptional regulator, rel operon repressor / antitoxin RelB 
C    YafQ-dinJ
C    YoeB-YefM
C    HipA-HipB
C    HicA-HicB
C    YafO-YafN
C    Hha-TomB
C    PspC-PspB
C    CcdB-CcdA
C    ParE-ParD
C    Doc-Phd
C    HigB-HigA
C    MqsR-MqsA
C    VapC-VapB
D      EXH44_05905 type II toxin-antitoxin system VapC family toxin	K18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-] 
D      EXH44_05900 AbrB/MazE/SpoVT family DNA-binding domain-containing protein	K18829 mvpT; antitoxin VapB 
C    PezT-PezA
C    YobL-YobK
C    YokI-YokJ
C    YqcG-YqcF
C    YxiD-YxxD
C    FitB-FitA
C    BC_0920-BC_0921
C    Type II TA system related factors
D      EXH44_09725 hypothetical protein	K03531 ftsZ; cell division protein FtsZ 
D      EXH44_03145 ftsZ; cell division protein FtsZ	K03531 ftsZ; cell division protein FtsZ 
D      EXH44_01755 rod shape-determining protein	K03569 mreB; rod shape-determining protein MreB and related proteins 
D      EXH44_10820 parC; DNA topoisomerase IV subunit A	K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2] 
D      EXH44_03120 parE; DNA topoisomerase IV subunit B	K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2] 
D      EXH44_07700 gltX; glutamate--tRNA ligase	K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17] 
B  Type III TA system
C    AbiQ system
B  Type IV TA system
C    YeeV-YeeU
C    CptA-CptB
D      EXH44_05795 succinate dehydrogenase assembly factor 2 family protein	K09159 cptB; antitoxin CptB 
B  Type V TA system
C    GhoT-GhoS
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A<b>DNA phosphothiolation system</b>
B  Sulfur modification proteins
C    EXH44_01595 IscS subfamily cysteine desulfurase	K04487 iscS; cysteine desulfurase [EC:2.8.1.7] 
B  DNA phosphorothioation-dependent restriction proteins
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#Last updated: November 7, 2023