+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Amycolatopsis japonica
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C AJAP_11510 Conserved putative membrane protein K03101 lspA; signal peptidase II [EC:3.4.23.36]
C AJAP_03520 Conserved putative membrane protein K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C AJAP_07320 Putative secreted protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C AJAP_38675 Putative membrane protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
C AJAP_25200 Putative membrane protein K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
C AJAP_39180 pcp; Pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C AJAP_35800 guaA; GMP synthase [glutamine-hydrolyzing] K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C AJAP_28615 Hypothetical protein K07010 K07010; putative glutamine amidotransferase
C AJAP_09100 Putative glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
B Family C40
C AJAP_10890 NLP/P60-family protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
C AJAP_38310 Hypothetical protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
C AJAP_20960 cell wall-associated hydrolase, invasion-associated protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
C AJAP_33660 Conserved putative secreted protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
C AJAP_20330 Hypothetical protein K21473 ripA; peptidoglycan DL-endopeptidase RipA [EC:3.4.-.-]
B Family C44
C AJAP_40570 purF; Amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C AJAP_11355 gltB1; Glutamate synthase [NADPH] large chain K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C AJAP_30990 gltB2; Glutamate synthase [NADPH] large chain K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C AJAP_02150 glmD; glucosamine-6-phosphate deaminase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C AJAP_36015 glmS2; Glutamine-fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C AJAP_13145 glmS1; Glutamine-fructose-6-phosphate aminotransferase [isomerizing] K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C AJAP_09530 asnO1; Asparagine synthetase [glutamine-hydrolyzing] 3 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C AJAP_36850 asnB2; asparagine synthase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C AJAP_10795 asnB1; Putative asparagine synthetase [glutamine-hydrolyzing] K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C AJAP_22565 asnO2; Asparagine synthetase [glutamine-hydrolyzing] 3 K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C AJAP_29800 intracellular protease PfpI family K05520 yhbO; deglycase [EC:3.5.1.124]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
C AJAP_30485 srtA; sortase K07284 srtA; sortase A [EC:3.4.22.70]
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C AJAP_09840 Conserved putative membrane protein K07052 K07052; CAAX protease family protein
C AJAP_09845 Conserved putative membrane protein K07052 K07052; CAAX protease family protein
C AJAP_14850 Conserved putative membrane protein K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
C AJAP_29915 pepN; Aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2]
C AJAP_19570 Hypothetical protein K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
B Family M3
C AJAP_18370 dcp; Peptidyl-dipeptidase dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
B Family M4: thermolysin family
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
C AJAP_19520 M6 family metalloprotease domain-containing protein K09607 ina; immune inhibitor A [EC:3.4.24.-]
B Family M7: snapalysin family
C AJAP_14045 snpA; Extracellular small neutral protease K01416 snpA; snapalysin [EC:3.4.24.77]
C AJAP_32715 peptidase M7 snapalysin K01416 snpA; snapalysin [EC:3.4.24.77]
B Family M8: leishmanolysin family
B Family M9
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
B Family M14: carboxypeptidase A family
C AJAP_00105 Zinc carboxypeptidase K05996 cpt; carboxypeptidase T [EC:3.4.17.18]
C AJAP_39370 scpD; Zinc carboxypeptidase K05996 cpt; carboxypeptidase T [EC:3.4.17.18]
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
C AJAP_20560 Zinc D-Ala-D-Ala carboxypeptidase K08640 E3.4.17.14; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
C AJAP_25730 Conserved putative membrane protein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
C AJAP_27755 dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
C AJAP_32165 vanX; D-alanyl-D-alanine dipeptidase K08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]
B Family M16: pitrilysin family
C AJAP_33865 Hypothetical protein K07263 pqqL; zinc protease [EC:3.4.24.-]
C AJAP_33870 Hypothetical protein K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C AJAP_34355 Hypothetical protein K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C AJAP_10705 pepA; Putative cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B Family M18
B Family M19: membrane dipeptidase family
C AJAP_02045 Hypothetical protein K01273 DPEP; membrane dipeptidase [EC:3.4.13.19]
B Family M20
C AJAP_12105 acetylornithine deacetylase/succinyldiaminopimelate desuccinylase-like deacylase K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]
C AJAP_17715 Hypothetical protein K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11]
C AJAP_34480 dapE; Succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C AJAP_12130 acetylornithine deacetylase ArgE K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
B Family M23
C AJAP_11495 Conserved putative secreted protein K08642 lasA; LasA protease [EC:3.4.24.-]
B Family M24
C AJAP_05440 map-1a; Methionine aminopeptidase 1 K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C AJAP_36205 map-1b; Methionine aminopeptidase 1 K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C AJAP_10170 map; Methionine aminopeptidase 2 K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C AJAP_21065 pepPI; Xaa-Pro aminopeptidase 1 K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
C AJAP_34460 Conserved putative secreted protein K19702 E3.4.11.24; aminopeptidase S [EC:3.4.11.24]
C AJAP_07200 aminopeptidase-like protein K19701 ywaD; aminopeptidase YwaD [EC:3.4.11.6 3.4.11.10]
C AJAP_38040 aminopeptidase-like protein K19701 ywaD; aminopeptidase YwaD [EC:3.4.11.6 3.4.11.10]
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
C AJAP_18470 Hypothetical protein K01417 MEP; extracellular elastinolytic metalloproteinase [EC:3.4.24.-]
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C AJAP_39300 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C AJAP_36730 htpX; Protease HtpX-like protein K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
B Family M54
B Family M55: DppA aminopeptidase family
C AJAP_19845 peptide/nickel transport system substrate-binding protein K16203 dppA1; D-amino peptidase [EC:3.4.11.-]
B Family M56
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
C AJAP_39260 Conserved putative membrane protein K24131 prsW; protease PrsW [EC:3.4.-.-]
B Family M85
B Family M88
B Family M90
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
C AJAP_16625 peptidase S58 K01266 dmpA; D-aminopeptidase [EC:3.4.11.19]
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C AJAP_34315 Conserved putative membrane protein K04771 degP; serine protease Do [EC:3.4.21.107]
C AJAP_03540 Conserved putative membrane protein K08372 pepD; putative serine protease PepD [EC:3.4.21.-]
C AJAP_07560 Conserved putative membrane protein K08372 pepD; putative serine protease PepD [EC:3.4.21.-]
C AJAP_20975 Conserved putative secreted protein K18546 sprC; streptogrisin C [EC:3.4.21.-]
C AJAP_15090 Streptogrisin-C K18546 sprC; streptogrisin C [EC:3.4.21.-]
C AJAP_18625 Conserved putative secreted protein K18546 sprC; streptogrisin C [EC:3.4.21.-]
C AJAP_21660 Streptogrisin-C K18546 sprC; streptogrisin C [EC:3.4.21.-]
C AJAP_12820 Conserved putative secreted protein K18546 sprC; streptogrisin C [EC:3.4.21.-]
C AJAP_22120 Conserved putative secreted protein K18547 sprD; streptogrisin D [EC:3.4.21.-]
C AJAP_21970 Conserved putative secreted protein K18547 sprD; streptogrisin D [EC:3.4.21.-]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C AJAP_36125 Conserved putative secreted protein K14743 mycP; membrane-anchored mycosin MYCP [EC:3.4.21.-]
C AJAP_08610 Conserved putative secreted protein K14743 mycP; membrane-anchored mycosin MYCP [EC:3.4.21.-]
C AJAP_10975 Conserved putative secreted protein K14743 mycP; membrane-anchored mycosin MYCP [EC:3.4.21.-]
C AJAP_10405 Conserved putative secreted protein K17734 aprX; serine protease AprX [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
C AJAP_26980 Putative peptidase y4nA K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C AJAP_25485 peptidase K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C AJAP_35320 Conserved putative secreted protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
C AJAP_39340 Conserved putative membrane protein K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C AJAP_29690 clpP1b; ATP-dependent Clp protease proteolytic subunit 1 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
C AJAP_29695 clpP2; ATP-dependent Clp protease proteolytic subunit 2 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
C AJAP_13255 clpP1a; ATP-dependent Clp protease proteolytic subunit 1 K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
C AJAP_13260 ATP-dependent Clp protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
C AJAP_28260 Conserved putative secreted protein K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
C AJAP_14380 Putative Xaa-Pro dipeptidyl-peptidase K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
C AJAP_26955 Conserved putative secreted protein K01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]
B Family S16: lon protease family
C AJAP_36605 lon; Lon protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C AJAP_33375 PDZ domain-containing protein K07177 K07177; Lon-like protease
B Family S21: assemblin family
B Family S24: LexA family
C AJAP_07905 lexA1; LexA repressor 1 K01356 lexA; repressor LexA [EC:3.4.21.88]
C AJAP_27040 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
B Family S26: signal peptidase I family
C AJAP_09875 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
C AJAP_24695 Hypothetical protein K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
C AJAP_30590 proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C AJAP_30140 Putative proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C AJAP_20410 Putative proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C AJAP_33570 pip; Proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C AJAP_16890 Hypothetical protein K01259 pip; proline iminopeptidase [EC:3.4.11.5]
C AJAP_20915 Hypothetical protein K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
B Family S41: C-terminal processing peptidase family
B Family S45
B Family S49: protease IV family
B Family S50
B Family S51
B Family S53
B Family S54: Rhomboid family
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
C AJAP_19720 Putative carboxypeptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C AJAP_20050 prcA; Proteasome subunit alpha K03432 psmA; proteasome alpha subunit [EC:3.4.25.1]
C AJAP_20055 prcB; Proteasome subunit beta K03433 psmB; proteasome beta subunit [EC:3.4.25.1]
B Family T2
B Family T3: gamma-glutamyltransferase family
C AJAP_00540 Putative gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C AJAP_25065 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
B Family U62
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2024
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Classification taken and modified from MEROPS