+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Histoplasma mississippiense
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E HCAG_05689 hypothetical protein K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E HCAG_05876 cell division control protein 2 K04563 CDC28; cyclin-dependent kinase [EC:2.7.11.22]
E HCAG_04046 serine/threonine-protein kinase crk1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E HCAG_07297 hypothetical protein K00987 CEG1; mRNA guanylyltransferase [EC:2.7.7.50]
D Cap binding complex
E HCAG_06885 hypothetical protein K12882 NCBP1; nuclear cap-binding protein subunit 1
E HCAG_07341 nuclear cap binding protein subunit 2 K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E HCAG_00337 similar to cleavage and polyadenylation specific factor 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
D Pre-mRNA cleavage factor IIm (CFIIm)
E HCAG_00864 hypothetical protein K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E HCAG_09100 hypothetical protein K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E HCAG_00822 hypothetical protein K14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1
E HCAG_05441 hypothetical protein K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E HCAG_02152 similar to cleavage and polyadenylation specifity factor, 73 kDa subunit K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E HCAG_04743 hypothetical protein K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E HCAG_04949 hypothetical protein K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E HCAG_02036 hypothetical protein K15541 MPE1; protein MPE1
E HCAG_07349 hypothetical protein K15542 PFS2; polyadenylation factor subunit 2
E HCAG_02584 WD repeat protein K14962 WDR82; COMPASS component SWD2
E HCAG_00807 similar to type 1 protein phosphtase-I K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E HCAG_04841 serine/threonine-protein phosphatase PP1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E HCAG_07996 serine/threonine-protein phosphatase PP-Z K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E HCAG_04482 similar to Ssu72p K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E HCAG_03684 hypothetical protein K14407 CSTF2; cleavage stimulation factor subunit 2
E HCAG_08775 hypothetical protein K14408 CSTF3; cleavage stimulation factor subunit 3
E HCAG_02724 hypothetical protein K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E HCAG_04232 hypothetical protein K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E HCAG_01311 hypothetical protein K11088 SNRPD3; small nuclear ribonucleoprotein D3
E HCAG_01049 hypothetical protein K11098 SNRPF; small nuclear ribonucleoprotein F
E HCAG_02780 small nuclear ribonucleoprotein SmG K11099 SNRPG; small nuclear ribonucleoprotein G
E HCAG_05441 hypothetical protein K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E HCAG_02152 similar to cleavage and polyadenylation specifity factor, 73 kDa subunit K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E HCAG_03684 hypothetical protein K14407 CSTF2; cleavage stimulation factor subunit 2
E HCAG_02724 hypothetical protein K06100 SYMPK; symplekin
D DRB sensitivity inducing factor (DSIF) complex
E HCAG_08376 hypothetical protein K15171 SUPT4H1; transcription elongation factor SPT4
E HCAG_06230 hypothetical protein K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
D Poly(A) addition factors
E HCAG_02302 Poly(A) polymerase PAPalpha K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
D Negative regulators of mRNA 3' end processing
C Other processing factors
D HCAG_03031 hypothetical protein K13102 KIN; DNA/RNA-binding protein KIN17
D HCAG_00272 hypothetical protein K27103 SRRT; serrate RNA effector molecule
D HCAG_05924 hypothetical protein K23039 NAB2; nuclear polyadenylated RNA-binding protein NAB2
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E HCAG_04531 hypothetical protein K12876 RBM8A; RNA-binding protein 8A
E HCAG_01815 mago nashi protein K12877 MAGOH; protein mago nashi
E HCAG_00740 hypothetical protein K12881 THOC4; THO complex subunit 4
E HCAG_08342 hypothetical protein K12881 THOC4; THO complex subunit 4
E HCAG_08343 hypothetical protein K12881 THOC4; THO complex subunit 4
E HCAG_05061 ATP-dependent RNA helicase SUB2 K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E HCAG_00406 eukaryotic initiation factor 4A-12 K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E HCAG_00015 hypothetical protein K25178 CCDC174; coiled-coil domain-containing protein 174
E HCAG_02131 hypothetical protein K14324 SAP18; histone deacetylase complex subunit SAP18
E HCAG_04267 hypothetical protein K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E HCAG_07756 hypothetical protein K12878 THOC1; THO complex subunit 1
E HCAG_02920 hypothetical protein K12879 THOC2; THO complex subunit 2
E HCAG_02921 hypothetical protein K12879 THOC2; THO complex subunit 2
E HCAG_01475 hypothetical protein K12880 THOC3; THO complex subunit 3
E HCAG_00740 hypothetical protein K12881 THOC4; THO complex subunit 4
E HCAG_08342 hypothetical protein K12881 THOC4; THO complex subunit 4
E HCAG_08343 hypothetical protein K12881 THOC4; THO complex subunit 4
E HCAG_07815 hypothetical protein K13174 THOC5; THO complex subunit 5
D TREX-2 complex
E HCAG_03400 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
E HCAG_02989 hypothetical protein K23719 SAC3; nuclear mRNA export protein SAC3
E HCAG_02990 hypothetical protein K23719 SAC3; nuclear mRNA export protein SAC3
D Nuclear pore complex
E HCAG_05208 hypothetical protein K09291 TPR; nucleoprotein TPR
E HCAG_01986 Poly(A)+ RNA export protein K14298 RAE1; mRNA export factor
E HCAG_08938 protein transport protein SEC13 K14004 SEC13; protein transport protein SEC13
E HCAG_03435 hypothetical protein K14308 NUP54; nuclear pore complex protein Nup54
E HCAG_04525 hypothetical protein K14306 NUP62; nuclear pore complex protein Nup62
E HCAG_07669 hypothetical protein K14309 NUP93; nuclear pore complex protein Nup93
E HCAG_01604 hypothetical protein K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E HCAG_02024 hypothetical protein K14300 NUP133; nuclear pore complex protein Nup133
E HCAG_00747 hypothetical protein K14311 NUP188; nuclear pore complex protein Nup188
E HCAG_07137 hypothetical protein K14312 NUP155; nuclear pore complex protein Nup155
E HCAG_02556 similar to cullin K14310 NUP205; nuclear pore complex protein Nup205
E HCAG_04952 hypothetical protein K14307 NUPL1; nucleoporin p58/p45
E HCAG_05599 hypothetical protein K14315 NDC1; nucleoporin NDC1
E HCAG_07102 hypothetical protein K14299 SEH1; nucleoporin SEH1
E HCAG_03736 hypothetical protein K18715 NUP159; nucleoporin NUP159
E HCAG_08820 hypothetical protein K18716 NUP42; nucleoporin NUP42
E HCAG_07342 hypothetical protein K18719 NUP82; nucleoporin NUP82
E HCAG_01823 hypothetical protein K18723 GLE1; nucleoporin GLE1
E HCAG_04245 hypothetical protein K14285 NXT1_2; NTF2-related export protein 1/2
E HCAG_03538 hypothetical protein K18725 POM152; nucleoporin POM152
D Ran-mediated transport factors
E HCAG_05187 GTP-binding nuclear protein GSP1/Ran K07936 RAN; GTP-binding nuclear protein Ran
E HCAG_02330 hypothetical protein K18726 FAF2; FAS-associated factor 2
E HCAG_02452 cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
E HCAG_01906 hypothetical protein K14319 RANGAP1; Ran GTPase-activating protein 1
D eIF4F and regulatory proteins
E HCAG_00523 hypothetical protein K03259 EIF4E; translation initiation factor 4E
E HCAG_07938 eukaryotic translation initiation factor 4E-1 K03259 EIF4E; translation initiation factor 4E
E HCAG_04273 eukaryotic initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E HCAG_08209 hypothetical protein K03260 EIF4G; translation initiation factor 4G
E HCAG_06478 hypothetical protein K03258 EIF4B; translation initiation factor 4B
E HCAG_04221 ATP-dependent RNA helicase ded1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E HCAG_07267 similar to dead box protein 4 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E HCAG_05961 hypothetical protein K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E HCAG_06026 polyadenylate-binding protein K13126 PABPC; polyadenylate-binding protein
E HCAG_08172 antiviral helicase SKI2 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E HCAG_07504 activating signal cointegrator 1 complex subunit 3 K18664 SLH1; antiviral helicase SLH1 [EC:5.6.2.6]
E HCAG_01446 hypothetical protein K07575 MCTS; malignant T-cell-amplified sequence
E HCAG_01889 hypothetical protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
D Other transport factors
E HCAG_05922 hypothetical protein K14294 WIBG; partner of Y14 and mago
E HCAG_03640 similar to A+U-rich RNA-binding protein K14411 MSI; RNA-binding protein Musashi
E HCAG_05804 similar to translation elongation factor 1-alpha K14416 HBS1; elongation factor 1 alpha-like protein
E HCAG_04572 hypothetical protein K06965 PELO; protein pelota
E HCAG_06160 hypothetical protein K14396 PABPN1; polyadenylate-binding protein 2
E HCAG_07208 similar to RNA helicase K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E HCAG_02641 pre-mRNA splicing factor syf-1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E HCAG_04633 hypothetical protein K18732 SARNP; SAP domain-containing ribonucleoprotein
E HCAG_07672 hypothetical protein K11493 RCC1; regulator of chromosome condensation
E HCAG_08015 hypothetical protein K23802 LENG8; SAC3 family protein LENG8/THP3
C Surveillance factors
D Surveillance complex
E HCAG_03051 eukaryotic peptide chain release factor subunit 1 K03265 ETF1; peptide chain release factor subunit 1
E HCAG_05778 similar to G1 to S phase transition 1 K03267 ERF3; peptide chain release factor subunit 3
E HCAG_00751 ATP-dependent helicase NAM7 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E HCAG_03838 hypothetical protein K14327 UPF2; regulator of nonsense transcripts 2
E HCAG_09005 hypothetical protein K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E HCAG_04969 serine/threonine protein phosphatase PP2A catalytic subunit K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E HCAG_00216 protein phosphatase PP2A regulatory subunit A K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E HCAG_02846 protein phosphatase PP2A regulatory subunit B K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E HCAG_00424 serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta 1 isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E HCAG_05961 hypothetical protein K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E HCAG_02563 hypothetical protein K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E HCAG_03407 hypothetical protein K14844 PUF6; pumilio homology domain family member 6
E HCAG_03732 hypothetical protein K18738 HEK; heterogeneous nuclear rnp K-like protein
E HCAG_06295 hypothetical protein K18738 HEK; heterogeneous nuclear rnp K-like protein
E HCAG_03105 similar to myosin 5B K10357 MYO5; myosin V
E HCAG_05091 hypothetical protein K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
E HCAG_05354 hypothetical protein K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
D Trans-acting binding proteins
E HCAG_01656 hypothetical protein K13210 FUBP; far upstream element-binding protein
E HCAG_08798 translation elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
E HCAG_08236 elongation factor 1 gamma domain-containing protein K03233 EEF1G; elongation factor 1-gamma
D Other mRNA localization factors
E HCAG_01822 hypothetical protein K18748 SSD1; protein SSD1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E HCAG_00485 hypothetical protein K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E HCAG_08776 hypothetical protein K11593 ELF2C; eukaryotic translation initiation factor 2C
E HCAG_00523 hypothetical protein K03259 EIF4E; translation initiation factor 4E
E HCAG_07938 eukaryotic translation initiation factor 4E-1 K03259 EIF4E; translation initiation factor 4E
E HCAG_00751 ATP-dependent helicase NAM7 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E HCAG_04221 ATP-dependent RNA helicase ded1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E HCAG_07267 similar to dead box protein 4 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E HCAG_09069 similar to ATP dependent RNA helicase Dhh1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E HCAG_01730 hypothetical protein K18749 LSM14; protein LSM14
E HCAG_02231 hypothetical protein K18752 TNPO1; transportin-1
E HCAG_00714 serine/threonine-protein kinase PRKX K04345 PKA; protein kinase A [EC:2.7.11.11]
E HCAG_03889 cAMP-dependent protein kinase type 2 K04345 PKA; protein kinase A [EC:2.7.11.11]
E HCAG_01455 hypothetical protein K18757 LARP1; la-related protein 1
D P-body specific factors
E HCAG_03934 hypothetical protein K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E HCAG_08281 small nuclear ribonucleoprotein LSM2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E HCAG_02564 hypothetical protein K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E HCAG_03909 similar to glycine-rich protein K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E HCAG_06383 hypothetical protein K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E HCAG_04071 similar to U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E HCAG_02332 hypothetical protein K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E HCAG_01854 hypothetical protein K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E HCAG_03105 similar to myosin 5B K10357 MYO5; myosin V
E HCAG_02068 tubulin alpha chain K07374 TUBA; tubulin alpha
E HCAG_08288 tubulin subunit alpha-2 K07374 TUBA; tubulin alpha
E HCAG_00094 hypothetical protein K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E HCAG_07833 hypothetical protein K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E HCAG_08835 hypothetical protein K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E HCAG_05763 hypothetical protein K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E HCAG_06068 hypothetical protein K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E HCAG_02880 CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E HCAG_09019 hypothetical protein K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E HCAG_02331 hypothetical protein K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E HCAG_00954 hypothetical protein K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E HCAG_02489 hypothetical protein K12615 EDC3; enhancer of mRNA-decapping protein 3
E HCAG_03838 hypothetical protein K14327 UPF2; regulator of nonsense transcripts 2
E HCAG_09005 hypothetical protein K14328 UPF3; regulator of nonsense transcripts 3
E HCAG_02811 similar to DNA-directed RNA polymerase II subunit K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
D Stress granule specific factors
E HCAG_09244 hypothetical protein K13201 TIA1; nucleolysin TIA-1/TIAR
E HCAG_06026 polyadenylate-binding protein K13126 PABPC; polyadenylate-binding protein
E HCAG_04683 hypothetical protein K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E HCAG_01253 hypothetical protein K15026 EIF2A; translation initiation factor 2A
E HCAG_03286 similar to eukaryotic translation initiation factor 3 K03253 EIF3B; translation initiation factor 3 subunit B
E HCAG_04273 eukaryotic initiation factor 4A K03257 EIF4A; translation initiation factor 4A
E HCAG_00406 eukaryotic initiation factor 4A-12 K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E HCAG_06478 hypothetical protein K03258 EIF4B; translation initiation factor 4B
E HCAG_08209 hypothetical protein K03260 EIF4G; translation initiation factor 4G
E HCAG_07031 similar to CPC2 protein K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E HCAG_09069 similar to ATP dependent RNA helicase Dhh1 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E HCAG_02489 hypothetical protein K12615 EDC3; enhancer of mRNA-decapping protein 3
E HCAG_00954 hypothetical protein K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E HCAG_03934 hypothetical protein K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E HCAG_08281 small nuclear ribonucleoprotein LSM2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E HCAG_02564 hypothetical protein K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E HCAG_03909 similar to glycine-rich protein K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E HCAG_06383 hypothetical protein K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E HCAG_04071 similar to U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E HCAG_02332 hypothetical protein K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E HCAG_01854 hypothetical protein K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E HCAG_00485 hypothetical protein K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
D Other 5'-3' decay factors
E HCAG_00981 hypothetical protein K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
C 3'-5' decay
D Core exosome factors
E HCAG_02509 hypothetical protein K07573 CSL4; exosome complex component CSL4
E HCAG_03457 hypothetical protein K03679 RRP4; exosome complex component RRP4
E HCAG_05387 hypothetical protein K03681 RRP40; exosome complex component RRP40
E HCAG_04484 hypothetical protein K11600 RRP41; exosome complex component RRP41
E HCAG_07214 hypothetical protein K12590 RRP46; exosome complex component RRP46
E HCAG_05940 hypothetical protein K12589 RRP42; exosome complex component RRP42
E HCAG_03200 hypothetical protein K12586 RRP43; exosome complex component RRP43
D Exosome cofactors
E HCAG_05461 exosome component 3'-5' exonuclease K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E HCAG_01190 hypothetical protein K12592 C1D; exosome complex protein LRP1
E HCAG_08061 hypothetical protein K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E HCAG_08104 hypothetical protein K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E HCAG_07044 hypothetical protein K12597 AIR1_2; protein AIR1/2
E HCAG_05592 ATP-dependent RNA helicase DOB1 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E HCAG_08172 antiviral helicase SKI2 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E HCAG_04344 hypothetical protein K12600 SKI3; superkiller protein 3
E HCAG_02005 hypothetical protein K12601 SKI8; superkiller protein 8
D Ccr4-NOT complex
E HCAG_06068 hypothetical protein K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E HCAG_00094 hypothetical protein K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E HCAG_07833 hypothetical protein K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E HCAG_08835 hypothetical protein K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E HCAG_05763 hypothetical protein K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E HCAG_02880 CCR4-NOT transcription complex subunit 7 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E HCAG_01697 cell differentiation protein Rcd1 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E HCAG_06877 hypothetical protein K12608 CAF16; CCR4-NOT complex subunit CAF16
D Pan complex
E HCAG_09019 hypothetical protein K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E HCAG_02331 hypothetical protein K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E HCAG_06542 hypothetical protein K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E HCAG_00981 hypothetical protein K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E HCAG_05177 hypothetical protein K26109 NRDE2; nuclear exosome regulator NRDE2
E HCAG_04848 hypothetical protein K27407 VTS1; RNA-binding protein VTS1
C Other degradation factors
D RNases
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E HCAG_06916 hypothetical protein K03685 rnc; ribonuclease III [EC:3.1.26.3]
E HCAG_08809 hypothetical protein K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E HCAG_07552 6-phosphofructokinase K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E HCAG_08176 heat shock protein SSC1, mitochondrial precursor K04043 dnaK; molecular chaperone DnaK
E HCAG_06961 heat shock protein 60, mitochondrial precursor K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E HCAG_03457 hypothetical protein K03679 RRP4; exosome complex component RRP4
E HCAG_02509 hypothetical protein K07573 CSL4; exosome complex component CSL4
D Cofactors
E HCAG_04484 hypothetical protein K11600 RRP41; exosome complex component RRP41
E HCAG_05940 hypothetical protein K12589 RRP42; exosome complex component RRP42
D Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 24, 2025