+D Protein KO
#
Membrane Trafficking - Histoplasma mississippiense
%
!
AExocytosis
B Calcium ion-dependent exocytosis
C Synaptotagmins
D HCAG_01609 hypothetical protein K28063 ESYT; extended synaptotagmin
D HCAG_04469 similar to transmembrane protein K28063 ESYT; extended synaptotagmin
C Septins
D HCAG_03836 cell division control protein 3 K16944 SEPT7; septin 7
C DOC-2 proteins
C Acrosomal exocytosis proteins
D HCAG_06643 hypothetical protein K06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]
C Phospholipases
D HCAG_03502 similar to phopholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D HCAG_06491 similar to phospholipase K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
C Kinases and associated proteins
D HCAG_01271 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D HCAG_09016 similar to P21-Activated Kinase family member K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
D HCAG_00350 similar to protein-serine/threonine kinase K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D HCAG_06393 similar to severin kinase K08838 STK24_25_MST4; serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1]
D HCAG_00544 nucleoside-diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D HCAG_01803 similar to non receptor serine/threonine kinase K19852 KIN1_2; serine/threonine protein kinase KIN1/2 [EC:2.7.11.1]
C Others
D HCAG_08632 neuronal calcium sensor 1 K19932 NCS1; neuronal calcium sensor
B Small GTPases and associated proteins
C Rab GTPases
D HCAG_07659 GTP-binding protein SAS1 K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
D HCAG_01325 calmodulin K02183 CALM; calmodulin
D HCAG_01195 hypothetical protein K19940 SEC2; Rab guanine nucleotide exchange factor SEC2
D HCAG_00958 hypothetical protein K15292 STXBP1; syntaxin-binding protein 1
D HCAG_08773 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
D HCAG_02965 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D HCAG_02894 hypothetical protein K19951 TBC1D8_9; TBC1 domain family member 8/9
D HCAG_02806 peroxisomal targeting signal receptor K13342 PEX5; peroxin-5
D HCAG_03194 hypothetical protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D HCAG_01685 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D HCAG_06364 type II proteins geranylgeranyltransferase beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D HCAG_06691 hypothetical protein K24155 DMXL; rabconnectin-3a
C Rho GTPases
D HCAG_01183 protein rho2 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Other small GTPases and associated proteins
B Tethering complex
C Exocyst complex
D HCAG_06042 hypothetical protein K19983 EXOC1; exocyst complex component 1
D HCAG_06043 hypothetical protein K19983 EXOC1; exocyst complex component 1
D HCAG_00766 hypothetical protein K17637 EXOC2; exocyst complex component 2
D HCAG_06105 hypothetical protein K06110 EXOC3; exocyst complex component 3
D HCAG_02991 hypothetical protein K06111 EXOC4; exocyst complex component 4
D HCAG_01905 hypothetical protein K19984 EXOC5; exocyst complex component 5
D HCAG_06911 hypothetical protein K19985 EXOC6; exocyst complex component 6
D HCAG_03913 hypothetical protein K07195 EXOC7; exocyst complex component 7
D HCAG_08361 hypothetical protein K19986 EXOC8; exocyst complex component 8
C Exocyst complex assembly proteins
D HCAG_03400 hypothetical protein K10881 SHFM1; 26 proteasome complex subunit DSS1
D HCAG_06375 hypothetical protein K17945 TPM1_2; tropomyosin, fungi type
B Others
C Exomer complex
D HCAG_03231 hypothetical protein K19877 CHS5; chitin biosynthesis protein CHS5
D HCAG_06633 hypothetical protein K19881 BUD7; Chs5-Arf1p-binding protein BUD7/BCH1
C Others
D HCAG_01134 hypothetical protein K12481 RBSN; rabenosyn-5
D HCAG_00557 hypothetical protein K19996 SFH5; phosphatidylinositol transfer protein SFH5
#
ASNARE
B Syntaxin (Qa)
C Stx-PM
D HCAG_07936 hypothetical protein K08486 STX1B_2_3; syntaxin 1B/2/3
C Stx-Endo
C Stx-TGN / EE
D HCAG_01326 hypothetical protein K08489 STX16; syntaxin 16
C Stx-cisGolgi
D HCAG_06473 hypothetical protein K08490 STX5; syntaxin 5
C Stx-sER
C Stx-rER
B SNAP-25[N] (Qb)
C Vti1
D HCAG_01675 hypothetical protein K08493 VTI1; vesicle transport through interaction with t-SNAREs 1
C NPSN
C Gos1 (Gos28)
D HCAG_03414 hypothetical protein K08495 GOSR1; golgi SNAP receptor complex member 1
C Bos1 / Membrin
D HCAG_03970 hypothetical protein K08496 GOSR2; golgi SNAP receptor complex member 2
C Sec20
D HCAG_04305 hypothetical protein K08497 SEC20; protein transport protein SEC20
B SNAP-25[C] (Qc)
C STX6
C STX8
D HCAG_05325 hypothetical protein K08502 VAM7; regulator of vacuolar morphogenesis
C STX10
C Bet1
D HCAG_01401 hypothetical protein K08504 BET1; blocked early in transport 1
D HCAG_03133 hypothetical protein K08504 BET1; blocked early in transport 1
C Sft1
C Syp7
C Use1
B SNAP-25 (Qb,c)
C SNAP-23
C SNAP-25
D HCAG_04628 hypothetical protein K19950 SEC9; protein transport protein SEC9
C SNAP-29
C SNAP-47
B VAMP, Ykt6, Sec22 (R)
C VAMP
D HCAG_05074 synaptobrevin K08513 VAMP4; vesicle-associated membrane protein 4
D HCAG_08352 hypothetical protein K08515 VAMP7; vesicle-associated membrane protein 7
C Ykt6
D HCAG_07503 hypothetical protein K08516 YKT6; synaptobrevin homolog YKT6
C Sec22
D HCAG_05142 protein transport protein sec22 K08517 SEC22; vesicle transport protein SEC22
C Tomosyn
D HCAG_08773 hypothetical protein K08518 STXBP5; syntaxin-binding protein 5
C Putative SNAREs
B SNARE associated proteins
C Syntaxin-binding proteins
D HCAG_00958 hypothetical protein K15292 STXBP1; syntaxin-binding protein 1
D HCAG_08899 similar to stxbp-unc-18-sec1 family protein K19998 SCFD1; sec1 family domain-containing protein 1
D HCAG_04251 hypothetical protein K26808 TXLN; taxilin
C Palmitoyltransferases
D HCAG_06484 hypothetical protein K20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2/15/20 [EC:2.3.1.225]
D HCAG_05703 hypothetical protein K20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]
D HCAG_07430 palmitoyltransferase akr1 K20032 ZDHHC13_17; palmitoyltransferase ZDHHC13/17 [EC:2.3.1.225]
C Others
D HCAG_06678 vesicle-fusing ATPase K06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]
D HCAG_03779 hypothetical protein K15296 NAPA; alpha-soluble NSF attachment protein
D HCAG_07017 hypothetical protein K17919 SNX4; sorting nexin-4
D HCAG_04009 sorting nexin-41 K21996 SNX41_42; sorting nexin-41/42
D HCAG_05511 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
D HCAG_02452 cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
D HCAG_04848 hypothetical protein K27407 VTS1; RNA-binding protein VTS1
#
AEndocytosis
B Clathrin-mediated endocytosis
C Clathrin
D HCAG_04225 clathrin heavy chain K04646 CLTC; clathrin heavy chain
C Dynamin
D HCAG_01882 similar to dynamin K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
C AP-2 complex
D HCAG_07753 similar to alpha-adaptin C K11824 AP2A; AP-2 complex subunit alpha
D HCAG_08087 hypothetical protein K11825 AP2B1; AP-2 complex subunit beta-1
D HCAG_02979 AP-2 complex subunit mu K11826 AP2M1; AP-2 complex subunit mu-1
D HCAG_06724 hypothetical protein K11827 AP2S1; AP-2 complex subunit sigma-1
C Other core components
D HCAG_06686 hypothetical protein K20042 FCHO; F-BAR domain only protein
D HCAG_04492 hypothetical protein K12471 EPN; epsin
D HCAG_05223 hypothetical protein K12471 EPN; epsin
D HCAG_02067 hypothetical protein K12472 EPS15; epidermal growth factor receptor substrate 15
D HCAG_07987 hypothetical protein K20044 PICALM; phosphatidylinositol-binding clathrin assembly protein
D HCAG_01146 similar to RVS167 protein K12562 AMPH; amphiphysin
D HCAG_02733 hypothetical protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D HCAG_06416 hypothetical protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D HCAG_08460 similar to sagA protein K20048 END3; actin cytoskeleton-regulatory complex protein END3
D HCAG_00806 heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C Low-density lipoprotein receptor (LDLR) family proteins
C LDLR adaptor proteins
D HCAG_01271 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
C GPCR adaptor proteins
D HCAG_02567 hypothetical protein K20059 LDB19; arrestin-related trafficking adapter 1
D HCAG_03464 hypothetical protein K20061 ALY1_2; arrestin-related trafficking adapter 3/6
D HCAG_09025 similar to carbon catabolite repression protein CreD K20062 ART4_5_7; arrestin-related trafficking adapter 4/5/7
D HCAG_07860 hypothetical protein K20063 RIM8; arrestin-related trafficking adapter 9
C Receptor tyrosine kinase (RTK) adaptor proteins
C Inositol 5-phosphatases
D HCAG_02965 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D HCAG_04077 hypothetical protein K20279 SYNJ; synaptojanin [EC:3.1.3.36]
C Kinases
D HCAG_00171 hypothetical protein K08853 AAK; AP2-associated kinase [EC:2.7.11.1]
D HCAG_08943 hypothetical protein K17541 SCYL2; SCY1-like protein 2
C Ubiquitin E3 ligases
D HCAG_06159 E3 ubiquitin--protein ligase pub1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C Others
D HCAG_01167 hypothetical protein K20040 HIP1R; huntingtin-interacting protein 1-related protein
D HCAG_06060 similar to calnexin K08054 CANX; calnexin
D HCAG_00874 hypothetical protein K20069 NECAP1_2; adaptin ear-binding coat-associated protein 1/2
B Lipid raft mediated endocytosis
C Caveolin-mediated endocytosis
D HCAG_01882 similar to dynamin K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
D HCAG_02636 similar to protein kinase C K02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]
C Flotillin-dependent endocytosis
D HCAG_07392 hypothetical protein K07192 FLOT; flotillin
D HCAG_09309 hypothetical protein K07192 FLOT; flotillin
C GRAF1-dependent endocytosis
C Arf6-dependent endocytosis
D HCAG_01103 ADP-ribosylation factor 6 K07941 ARF6; ADP-ribosylation factor 6
D HCAG_01183 protein rho2 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C RhoA-dependent endocytosis
D HCAG_05560 similar to rho GTPase K04513 RHOA; Ras homolog gene family, member A
D HCAG_01882 similar to dynamin K17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]
B Phagocytosis
C Fc receptors
C Integrins (complement receptors)
C Opsonins
C Toll-like receptors
C C-lectin receptors
C Scavenger receptors
C Coronins
C Others
D HCAG_06165 myosin-1 K10356 MYO1; myosin I
B Macropinocytosis
C Ras GTPases
D HCAG_00894 protein ras-1 K07827 KRAS; GTPase KRas
D HCAG_03498 hypothetical protein K07827 KRAS; GTPase KRas
D HCAG_07420 GTPase NRas precursor K07827 KRAS; GTPase KRas
D HCAG_01183 protein rho2 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
C Kinases
D HCAG_00704 similar to phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D HCAG_07780 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D HCAG_09016 similar to P21-Activated Kinase family member K04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]
C Phospholipase C
C Sorting nexins
D HCAG_06062 hypothetical protein K17917 SNX1_2; sorting nexin-1/2
C Others
B Bin/Amphiphysin/Rvs (BAR) family proteins
C N-BAR proteins
D HCAG_01146 similar to RVS167 protein K12562 AMPH; amphiphysin
C F-BAR proteins
D HCAG_07209 hypothetical protein K20121 FNBP1; formin-binding protein 1
D HCAG_06686 hypothetical protein K20042 FCHO; F-BAR domain only protein
D HCAG_01182 hypothetical protein K20643 RGD1; Rho GTPase-activating protein RGD1
C I-BAR proteins
B Rab GTPases and associated proteins
C Rab GTPases
D HCAG_06262 GTP-binding protein ypt5 K07888 RAB5B; Ras-related protein Rab-5B
C Rab associated proteins
D HCAG_00797 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D HCAG_01134 hypothetical protein K12481 RBSN; rabenosyn-5
D HCAG_02965 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D HCAG_00704 similar to phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D HCAG_01068 similar to possible kinase with calcium binding domain K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D HCAG_08251 vacuolar protein sorting-associated protein 45 K12479 VPS45; vacuolar protein sorting-associated protein 45
B Arf GTPases and associated proteins
C Arf GTPases
D HCAG_01103 ADP-ribosylation factor 6 K07941 ARF6; ADP-ribosylation factor 6
C Arf associated proteins
D HCAG_03132 hypothetical protein K12486 SMAP; stromal membrane-associated protein
B Others
C Fucosyltransferase
C EFR3-PI4KIII alpha complex and associated proteins
D HCAG_04050 similar to Stt4p: phosphatidylinositol-4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D HCAG_08790 hypothetical protein K21842 EFR3; protein EFR3
D HCAG_09038 hypothetical protein K21845 YPP1; cargo-transport protein YPP1
C Insulin-like growth factor-binding proteins
C Others
#
AEndosome - Lysosome transport
B Rab GTPases and associated proteins
C Rab GTPases
D HCAG_06262 GTP-binding protein ypt5 K07888 RAB5B; Ras-related protein Rab-5B
D HCAG_02618 GTP-binding protein YPT7 K07897 RAB7A; Ras-related protein Rab-7A
C Retromer subcomplex
D HCAG_00111 hypothetical protein K18468 VPS35; vacuolar protein sorting-associated protein 35
D HCAG_01489 vacuolar protein sorting-associated protein 26 K18466 VPS26A_B; vacuolar protein sorting-associated protein 26A/B
C FTS/Hook/FHIP (FHF) complex
D HCAG_01405 hypothetical protein K16536 HOOK3; protein HOOK3
C FERRY complex
C Rab associated proteins
D HCAG_00704 similar to phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D HCAG_00347 proteasome component PRE6 K02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]
D HCAG_06291 hypothetical protein K18469 TBC1D5; TBC1 domain family member 5
D HCAG_05114 GTPase-activating protein GYP7 K20168 TBC1D15; TBC1 domain family member 15
D HCAG_03194 hypothetical protein K23460 CHM; Rab proteins geranylgeranyltransferase component A
D HCAG_01685 hypothetical protein K14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]
D HCAG_06364 type II proteins geranylgeranyltransferase beta subunit K05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]
D HCAG_01064 hypothetical protein K20176 SGSM3; small G protein signaling modulator 3
D HCAG_05511 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
B Arf GTPases and associated proteins
C Arf GTPases
D HCAG_05908 hypothetical protein K07955 ARL8; ADP-ribosylation factor-like protein 8
C BLOC-one-related complex (BORC)
C N-acetyl transferase complex C (NatC)
D HCAG_05470 hypothetical protein K00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]
D HCAG_06964 hypothetical protein K20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit
D HCAG_07746 hypothetical protein K20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit
C Other Arf associated proteins
B Endosomal sorting complexes required for transport (ESCRT)
C ESCRT-0 complex
D HCAG_05808 hypothetical protein K12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate
D HCAG_09015 hypothetical protein K04705 STAM; signal transducing adaptor molecule
C ESCRT-I complex
D HCAG_01151 hypothetical protein K12183 TSG101; ESCRT-I complex subunit TSG101
D HCAG_02174 hypothetical protein K12184 VPS28; ESCRT-I complex subunit VPS28
C ESCRT-II complex
D HCAG_08705 hypothetical protein K12188 SNF8; ESCRT-II complex subunit VPS22
D HCAG_06132 hypothetical protein K12189 VPS25; ESCRT-II complex subunit VPS25
D HCAG_08016 hypothetical protein K12190 VPS36; ESCRT-II complex subunit VPS36
C ESCRT-III complex
D HCAG_07627 hypothetical protein K12197 CHMP1; charged multivesicular body protein 1
D HCAG_02484 similar to charged multivesicular body protein 2a K12191 CHMP2A; charged multivesicular body protein 2A
D HCAG_08344 hypothetical protein K12193 VPS24; charged multivesicular body protein 3
D HCAG_05491 hypothetical protein K12194 CHMP4A_B; charged multivesicular body protein 4A/B
D HCAG_01600 hypothetical protein K12198 CHMP5; charged multivesicular body protein 5
D HCAG_01966 hypothetical protein K12195 CHMP6; charged multivesicular body protein 6
D HCAG_06510 hypothetical protein K15053 CHMP7; charged multivesicular body protein 7
D HCAG_05411 vacuolar protein sorting-associated protein VPS4 K12196 VPS4; vacuolar protein-sorting-associated protein 4
C ESCRT associated proteins
D HCAG_04796 hypothetical protein K12199 VTA1; vacuolar protein sorting-associated protein VTA1
D HCAG_08972 hypothetical protein K12200 PDCD6IP; programmed cell death 6-interacting protein
B Tethering complex
C CORVET complex
D HCAG_02336 hypothetical protein K20177 VPS3; vacuolar protein sorting-associated protein 3
D HCAG_04807 hypothetical protein K20178 VPS8; vacuolar protein sorting-associated protein 8
D HCAG_00327 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D HCAG_02495 hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D HCAG_09050 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D HCAG_04627 similar to vacuolar sorting protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
C Hops complex
D HCAG_00327 hypothetical protein K20179 VPS11; vacuolar protein sorting-associated protein 11
D HCAG_02495 hypothetical protein K20180 VPS16; vacuolar protein sorting-associated protein 16
D HCAG_09050 hypothetical protein K20181 VPS18; vacuolar protein sorting-associated protein 18
D HCAG_04627 similar to vacuolar sorting protein K20182 VPS33A; vacuolar protein sorting-associated protein 33A
D HCAG_03953 hypothetical protein K20183 VPS39; Vam6/Vps39-like protein vacuolar protein sorting-associated protein 39
D HCAG_06571 hypothetical protein K20184 VPS41; vacuolar protein sorting-associated protein 41
B Acidification regulators
C Rabconnectin-3 complex
D HCAG_06691 hypothetical protein K24155 DMXL; rabconnectin-3a
C RAVE complex
D HCAG_06691 hypothetical protein K24155 DMXL; rabconnectin-3a
D HCAG_03008 sulfur metabolite repression control protein C K03094 SKP1; S-phase kinase-associated protein 1
B Others
C AP-3 complex
D HCAG_04074 hypothetical protein K12396 AP3D; AP-3 complex subunit delta
D HCAG_00869 hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D HCAG_07062 hypothetical protein K12398 AP3M; AP-3 complex subunit mu
D HCAG_05220 AP-3 complex subunit sigma K12399 AP3S; AP-3 complex subunit sigma
C BLOC-1 complex
C BLOC-1 complex (yeast)
D HCAG_06680 hypothetical protein K22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1
C BLOC-2 complex
C BLOC-3 complex
C Ferlins
C Lysosomal membrane proteins
D HCAG_00821 hypothetical protein K14617 LMBRD1; LMBR1 domain-containing protein 1
C Others
D HCAG_03726 hypothetical protein K20195 MON1; vacuolar fusion protein MON1
D HCAG_05807 hypothetical protein K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D HCAG_04350 hypothetical protein K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
D HCAG_06142 hypothetical protein K23879 GRN; progranulin
D HCAG_08214 hypothetical protein K28212 LEPROT; OB-RGRP/VPS55 family protein
D HCAG_00403 vacuolar sorting protein 1 K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AProtein recycling
B Rab GTPases and associated proteins
C Rab GTPases
D HCAG_04377 hypothetical protein K07880 RAB4B; Ras-related protein Rab-4B
D HCAG_06999 Rab1a K07904 RAB11A; Ras-related protein Rab-11A
C Rab4 associated proteins
D HCAG_01134 hypothetical protein K12481 RBSN; rabenosyn-5
D HCAG_07017 hypothetical protein K17919 SNX4; sorting nexin-4
D HCAG_00720 hypothetical protein K10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain
C Rab11 associated proteins
D HCAG_02602 hypothetical protein K20241 WDR44; WD repeat-containing protein 44
D HCAG_08938 protein transport protein SEC13 K14004 SEC13; protein transport protein SEC13
D HCAG_06911 hypothetical protein K19985 EXOC6; exocyst complex component 6
D HCAG_05511 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
C Other Rab GTPase associated proteins
D HCAG_02965 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D HCAG_00797 hypothetical protein K20131 RABGEF1; Rab5 GDP/GTP exchange factor
D HCAG_03403 DNA repair protein RAD51 K04482 RAD51; DNA repair protein RAD51
B Others
C Glutamate receptor-interacting proteins (GRIPs)
C GRIP associated proteins
C EARP complex
D HCAG_04345 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D HCAG_06022 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D HCAG_04857 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
C WASH complex
D HCAG_05796 hypothetical protein K10364 CAPZA; F-actin-capping protein subunit alpha
D HCAG_04752 F-actin capping protein beta subunit K10365 CAPZB; F-actin-capping protein subunit beta
C Retriever complex
C Others
D HCAG_07778 hypothetical protein K21440 ANKRD50; ankyrin repeat domain-containing protein 50
#
AEndosome - Golgi transport
B Rab GTPases and associated proteins
C Rab GTPases
C Rab associated proteins
D HCAG_05511 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
D HCAG_02894 hypothetical protein K19951 TBC1D8_9; TBC1 domain family member 8/9
D HCAG_03439 hypothetical protein K20286 TMF1; TATA element modulatory factor
D HCAG_05994 similar to p150 dynactin NUDM K04648 DCTN1; dynactin 1
D HCAG_02965 hypothetical protein K01099 INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F [EC:3.1.3.36]
D HCAG_01547 hypothetical protein K19525 VPS13A_C; vacuolar protein sorting-associated protein 13A/C
B Arf GTPases and associated proteins
C Arf GTPases
D HCAG_08067 ADP-ribosylation factor K07942 ARL1; ADP-ribosylation factor-like protein 1
D HCAG_02134 hypothetical protein K07952 ARFRP1; ADP-ribosylation factor related protein 1
C Arf GTPase associated proteins
D HCAG_02915 hypothetical protein K12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1
D HCAG_08186 hypothetical protein K12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2/3
D HCAG_03132 hypothetical protein K12486 SMAP; stromal membrane-associated protein
D HCAG_04054 hypothetical protein K12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
D HCAG_03973 hypothetical protein K18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein
D HCAG_02643 hypothetical protein K18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1
B Tethering complex
C Conserved oligomeric Golgi (COG) complex
D HCAG_05133 hypothetical protein K20288 COG1; conserved oligomeric Golgi complex subunit 1
D HCAG_00550 hypothetical protein K20289 COG2; conserved oligomeric Golgi complex subunit 2
D HCAG_06588 hypothetical protein K20290 COG3; conserved oligomeric Golgi complex subunit 3
D HCAG_03663 hypothetical protein K20291 COG4; conserved oligomeric Golgi complex subunit 4
D HCAG_05277 hypothetical protein K20293 COG6; conserved oligomeric Golgi complex subunit 6
D HCAG_00077 hypothetical protein K20295 COG8; conserved oligomeric Golgi complex subunit 8
C GARP complex
D HCAG_04345 hypothetical protein K20296 ANG2; vacuolar protein sorting-associated protein 51
D HCAG_06022 hypothetical protein K20298 VPS52; vacuolar protein sorting-associated protein 52
D HCAG_04857 hypothetical protein K20299 VPS53; vacuolar protein sorting-associated protein 53
D HCAG_00180 hypothetical protein K17600 VPS54; vacuolar protein sorting-associated protein 54
D HCAG_00416 hypothetical protein K17600 VPS54; vacuolar protein sorting-associated protein 54
C TRAPP complex II
D HCAG_03011 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D HCAG_07326 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D HCAG_04403 BET3 family protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D HCAG_00248 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D HCAG_02546 hypothetical protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D HCAG_06902 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
D HCAG_06509 hypothetical protein K20305 TRAPPC8; trafficking protein particle complex subunit 8
D HCAG_08222 similar to hypercellular protein A K20306 TRAPPC9; trafficking protein particle complex subunit 9
D HCAG_01867 hypothetical protein K20307 TRAPPC10; trafficking protein particle complex subunit 10
D HCAG_01973 hypothetical protein K20308 TRAPPC11; trafficking protein particle complex subunit 11
D HCAG_00115 hypothetical protein K20309 TRAPPC12; trafficking protein particle complex subunit 12
D HCAG_08975 hypothetical protein K20310 TRAPPC13; trafficking protein particle complex subunit 13
B Others
C AP-1 complex
D HCAG_00157 hypothetical protein K12391 AP1G1; AP-1 complex subunit gamma-1
D HCAG_04363 similar to adaptor protein complex AP-1 K12392 AP1B1; AP-1 complex subunit beta-1
D HCAG_00598 AP-1 adaptor complex subunit mu K12393 AP1M; AP-1 complex subunit mu
D HCAG_01154 similar to clathrin coat assembly protein K12394 AP1S1_2; AP-1 complex subunit sigma 1/2
C AP-3 complex
D HCAG_04074 hypothetical protein K12396 AP3D; AP-3 complex subunit delta
D HCAG_00869 hypothetical protein K12397 AP3B; AP-3 complex subunit beta
D HCAG_07062 hypothetical protein K12398 AP3M; AP-3 complex subunit mu
D HCAG_05220 AP-3 complex subunit sigma K12399 AP3S; AP-3 complex subunit sigma
C AP-4 complex
C GGA
D HCAG_05521 hypothetical protein K12404 GGA; ADP-ribosylation factor-binding protein GGA
C Aftiphilin/p200/gamma-synergin complex
D HCAG_05136 hypothetical protein K24814 HEATR5; HEAT repeat-containing protein 5
C Others
D HCAG_03502 similar to phopholipase D K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D HCAG_06491 similar to phospholipase K01115 PLD1_2; phospholipase D1/2 [EC:3.1.4.4]
D HCAG_04050 similar to Stt4p: phosphatidylinositol-4-kinase K00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]
D HCAG_01271 hypothetical protein K00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]
D HCAG_07780 hypothetical protein K00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]
D HCAG_01508 hypothetical protein K20316 SCOC; short coiled-coil protein
D HCAG_04528 hypothetical protein K20316 SCOC; short coiled-coil protein
D HCAG_06328 hypothetical protein K20316 SCOC; short coiled-coil protein
D HCAG_05448 hypothetical protein K20318 SYS1; protein SYS1
D HCAG_07257 hypothetical protein K23541 TMEM165; Ca2+/H+ antiporter, TMEM165/GDT1 family
D HCAG_05395 hypothetical protein K23542 TMEM199; TMEM199 family protein
D HCAG_05976 hypothetical protein K23544 SERINC1; serine incorporator 1
D HCAG_07240 sorting nexin-3 K17918 SNX3_12; sorting nexin-3/12
D HCAG_02455 hypothetical protein K17922 SNX8; sorting nexin-8
D HCAG_01488 hypothetical protein K26678 MON2; protein MON2
D HCAG_03725 protein dopey K26680 DOP1; protein dopey
D HCAG_00579 hypothetical protein K27894 HID1; protein HID1
D HCAG_00883 hypothetical protein K26750 TVP15; golgi apparatus membrane protein TVP15
D HCAG_00132 hypothetical protein K26751 TVP18; golgi apparatus membrane protein TVP18
D HCAG_07023 hypothetical protein K26752 TVP23; golgi apparatus membrane protein TVP23
D HCAG_07021 hypothetical protein K26753 TVP38; golgi apparatus membrane protein TVP38
D HCAG_00403 vacuolar sorting protein 1 K23481 VPS1; vacuolar protein sorting-associated protein 1
#
AEndoplasmic reticulum (ER) - Golgi transport
B Forward pathways
C Coat protein complex II (COP-II)
D HCAG_04840 GTP-binding protein sarA K07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]
D HCAG_08938 protein transport protein SEC13 K14004 SEC13; protein transport protein SEC13
D HCAG_03764 hypothetical protein K14005 SEC31; protein transport protein SEC31
D HCAG_04789 similar to SEC23B K14006 SEC23; protein transport protein SEC23
D HCAG_05252 hypothetical protein K14007 SEC24; protein transport protein SEC24
D HCAG_05444 hypothetical protein K14007 SEC24; protein transport protein SEC24
D HCAG_05119 hypothetical protein K20353 SEC16; COPII coat assembly protein SEC16
C TRAPP complex I
D HCAG_03011 hypothetical protein K20300 TRAPPC1; trafficking protein particle complex subunit 1
D HCAG_07326 hypothetical protein K20301 TRAPPC2; trafficking protein particle complex subunit 2
D HCAG_04403 BET3 family protein K20302 TRAPPC3; trafficking protein particle complex subunit 3
D HCAG_00248 hypothetical protein K20303 TRAPPC4; trafficking protein particle complex subunit 4
D HCAG_02546 hypothetical protein K20280 TRAPPC5; trafficking protein particle complex subunit 5
D HCAG_06902 hypothetical protein K20304 TRAPPC6; trafficking protein particle complex subunit 6
C p24 family proteins
D HCAG_05563 hypothetical protein K20346 TMED4_9_11; p24 family protein alpha
D HCAG_07033 hypothetical protein K20352 TMED10; p24 family protein delta-1
C PDI family proteins
D HCAG_03630 protein disulfide-isomerase precursor K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
D HCAG_02591 protein disulfide-isomerase tigA precursor K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
D HCAG_04802 hypothetical protein K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C Rab GTPases
D HCAG_06941 GTP-binding protein ypt1 K07874 RAB1A; Ras-related protein Rab-1A
C Rab associated proteins
D HCAG_04148 hypothetical protein K20359 RABAC1; PRA1 family protein 1
D HCAG_06017 hypothetical protein K20372 TBC1D20; TBC1 domain family member 20
D HCAG_03641 similar to novel protein K20360 TBC1D22; TBC1 domain family member 2
D HCAG_05106 Hrf1 domain protein K20362 YIF1; protein transport protein YIF1
D HCAG_06055 hypothetical protein K22939 IER3IP1; immediate early response 3-interacting protein 1
D HCAG_06695 similar to intracellular protein transport protein UsoA K20361 USO1; intracellular protein transport protein USO1
C ER-Golgi intermediate compartment (ERGIC) proteins
D HCAG_06520 hypothetical protein K10080 LMAN1; lectin, mannose-binding 1
D HCAG_03891 hypothetical protein K10082 LMAN2; lectin, mannose-binding 2
D HCAG_01179 hypothetical protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D HCAG_02354 mannosyl-oligosaccharide alpha-1,2-mannosidase precursor K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D HCAG_05294 hypothetical protein K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D HCAG_05335 similar to alpha-mannosidase IC K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D HCAG_06505 similar to class I alpha-mannosidase K01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]
D HCAG_04182 mannosyl-oligosaccharide 1,2-alpha-mannosidase K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D HCAG_08449 mannosyl-oligosaccharide 1,2-alpha-mannosidase K23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]
D HCAG_01157 hypothetical protein K20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2
D HCAG_04858 hypothetical protein K20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3
D HCAG_07797 ER-derived vesicles protein ERV14 K20368 CNIH; protein cornichon
D HCAG_01857 hypothetical protein K20369 ERV29; ER-derived vesicles protein
D HCAG_05805 heat shock 70 kDa protein C precursor K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
B Retrieval pathways
C Coat protein complex I (COP-I)
D HCAG_04366 coatomer alpha subunit K05236 COPA; coatomer subunit alpha
D HCAG_01814 coatomer beta subunit K17301 COPB1; coatomer subunit beta
D HCAG_08724 coatomer beta' subunit K17302 COPB2; coatomer subunit beta'
D HCAG_05330 similar to coatomer protein complex K17267 COPG; coatomer subunit gamma
D HCAG_02251 similar to coatomer subunit delta K20471 COPD; coatomer subunit delta
D HCAG_08438 hypothetical protein K17268 COPE; coatomer subunit epsilon
D HCAG_03691 hypothetical protein K20472 COPZ; coatomer subunit zeta
C NRZ (DSL1) complex
D HCAG_06584 hypothetical protein K20474 RINT1; RAD50-interacting protein 1
D HCAG_04212 hypothetical protein K11578 ZW10; protein transport protein DSL1/ZW10
D HCAG_00184 hypothetical protein K20475 SEC39; protein transport protein SEC39
C Golgi to ER traffic proteins (GET)
D HCAG_08959 hypothetical protein K22384 GET1; tail-anchored protein insertion receptor
D HCAG_01608 hypothetical protein K22386 GET2; GET complex subunit GET2
D HCAG_00048 arsenical pump-driving ATPase K01551 arsA; arsenite/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]
D HCAG_06874 hypothetical protein K23387 GET4; golgi to ER traffic protein 4
D HCAG_07229 hypothetical protein K23388 UBL4; ubiquitin-like protein 4
C Rab GTPases
C Rab associated proteins
D HCAG_01445 hypothetical protein K20476 RIC1; RAB6A-GEF complex partner protein 1
D HCAG_03812 hypothetical protein K20477 RGP1; RAB6A-GEF complex partner protein 2
D HCAG_06921 ER lumen protein retaining receptor 2 K10949 KDELR; ER lumen protein retaining receptor
D HCAG_01134 hypothetical protein K12481 RBSN; rabenosyn-5
D HCAG_03641 similar to novel protein K20360 TBC1D22; TBC1 domain family member 2
B Others
C Oxysterol-binding proteins
D HCAG_04386 similar to OSBPL2 K20456 OSBP; oxysterol-binding protein 1
D HCAG_03458 hypothetical protein K20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3/6/7
D HCAG_04476 similar to oxysterol-binding protein K22285 OSBPL8; oxysterol-binding protein-related protein 8
D HCAG_00003 similar to oxysterol binding protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
D HCAG_09326 hypothetical protein K20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9/10/11
C FXYD proteins
C YIPF proteins
D HCAG_08041 hypothetical protein K22943 YIPF6; protein YIPF6
C ER membrane protein complex
D HCAG_00650 hypothetical protein K23562 EMC1; ER membrane protein complex subunit 1
D HCAG_04075 hypothetical protein K23563 EMC2; ER membrane protein complex subunit 2
D HCAG_02816 hypothetical protein K23564 EMC3; ER membrane protein complex subunit 3
D HCAG_08088 hypothetical protein K23565 EMC4; ER membrane protein complex subunit 4
D HCAG_01818 hypothetical protein K23566 MMGT1; membrane magnesium transporter 1
D HCAG_04849 hypothetical protein K23567 EMC6; ER membrane protein complex subunit 6
D HCAG_06956 hypothetical protein K23568 EMC7; ER membrane protein complex subunit 7
C SEC61 complex
D HCAG_02998 protein transport protein SEC61 alpha subunit K10956 SEC61A; protein transport protein SEC61 subunit alpha
D HCAG_07242 hypothetical protein K07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins
C TRAP complex
C Multi-pass translocon (MPT) complex
D HCAG_01340 hypothetical protein K24962 CCDC47; PAT complex subunit CCDC47
C Post-GPI attachment to proteins factors (PGAP)
D HCAG_03853 hypothetical protein K05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]
D HCAG_00065 hypothetical protein K23553 PGAP3; post-GPI attachment to proteins factor 3
D HCAG_04259 hypothetical protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
D HCAG_04520 hypothetical protein K23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]
C Others
D HCAG_08899 similar to stxbp-unc-18-sec1 family protein K19998 SCFD1; sec1 family domain-containing protein 1
D HCAG_03835 hypothetical protein K20724 TMEM33; transmembrane protein 33
D HCAG_03919 hypothetical protein K21850 KRE6; beta-glucan synthesis-associated protein KRE6
D HCAG_05511 vacuolar protein sorting-associated protein 74 K15620 GOLPH3; golgi phosphoprotein 3
D HCAG_04223 hypothetical protein K26681 INSIG; insulin-induced protein
D HCAG_07507 hypothetical protein K26683 GOLT1; vesicle transport protein GOT1
D HCAG_03442 hypothetical protein K22698 SEY1; protein SEY1 [EC:3.6.5.-]
#
AAutophagy
B Autophagosome formation proteins
C ULK complex
D HCAG_05812 hypothetical protein K08331 ATG13; autophagy-related protein 13
D HCAG_08387 hypothetical protein K19730 ATG101; autophagy-related protein 101
C Atg1 complex
D HCAG_07089 hypothetical protein K08269 ULK2; serine/threonine-protein kinase ULK2 [EC:2.7.11.1]
D HCAG_05812 hypothetical protein K08331 ATG13; autophagy-related protein 13
D HCAG_03861 hypothetical protein K08329 ATG17; autophagy-related protein 17
C PI3K complex
D HCAG_00704 similar to phosphatidylinositol 3-kinase K00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]
D HCAG_01068 similar to possible kinase with calcium binding domain K08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]
D HCAG_02801 hypothetical protein K08334 BECN; beclin
C ATG9 transmembrane protein
D HCAG_05295 hypothetical protein K17907 ATG9; autophagy-related protein 9
C Atg18-Atg2 complex
D HCAG_00833 hypothetical protein K17908 WIPI1_2; autophagy-related protein 18
D HCAG_05201 hypothetical protein K17906 ATG2; autophagy-related protein 2
C Atg12 conjugation proteins
D HCAG_05834 hypothetical protein K08336 ATG12; ubiquitin-like protein ATG12
D HCAG_02033 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D HCAG_04113 hypothetical protein K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
D HCAG_07891 hypothetical protein K08339 ATG5; autophagy-related protein 5
C Atg8 conjugation proteins
D HCAG_03526 hypothetical protein K08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]
D HCAG_02033 hypothetical protein K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
D HCAG_08397 hypothetical protein K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
B Cytoplasm to vacuolar targeting (CVT) pathway
C Selective cargos
D HCAG_00603 hypothetical protein K01268 LAP4; aminopeptidase I [EC:3.4.11.22]
D HCAG_04277 similar to mannosidase II K01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]
D HCAG_04297 similar to aspartyl aminopeptidase K01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]
C Cargo receptors
C Scaffold protein
D HCAG_00016 hypothetical protein K08330 ATG11; autophagy-related protein 11
C Other Cvt associated proteins
D HCAG_04009 sorting nexin-41 K21996 SNX41_42; sorting nexin-41/42
D HCAG_07017 hypothetical protein K17919 SNX4; sorting nexin-4
D HCAG_08049 hypothetical protein K17900 ATG15; lipase ATG15 [EC:3.1.1.3]
D HCAG_06784 hypothetical protein K21141 ATG27; autophagy-related protein 27
D HCAG_02510 vacuolar protein 8 K08332 VAC8; vacuolar protein 8
B Mitophagy
C Cargo receptors
C Scaffold proteins
D HCAG_00016 hypothetical protein K08330 ATG11; autophagy-related protein 11
C PINK1-Parkin associated proteins
D HCAG_02485 hypothetical protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
D HCAG_03477 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other mitophagy associated proteins
D HCAG_03191 glucokinase K00844 HK; hexokinase [EC:2.7.1.1]
D HCAG_03661 hexokinase K00844 HK; hexokinase [EC:2.7.1.1]
D HCAG_08145 hypothetical protein K00844 HK; hexokinase [EC:2.7.1.1]
D HCAG_04526 hypothetical protein K22255 ATPIF1; ATPase inhibitor, mitochondrial
D HCAG_02898 hypothetical protein K19717 ATG33; autophagy-related protein 33
B Pexophagy
C Selective cargos
D HCAG_00090 hypothetical protein K13343 PEX14; peroxin-14
C Cargo receptors
C Other pexophagy associated proteins
D HCAG_03477 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
D HCAG_06368 similar to peroxin-1 K13338 PEX1; peroxin-1
D HCAG_00234 peroxisomal biogenesis factor 6 K13339 PEX6; peroxin-6
B Aggrephagy
C Cargo receptors
D HCAG_03477 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Scaffold proteins
C Other aggrephagy associated proteins
D HCAG_02452 cell division cycle protein 48 K13525 VCP; transitional endoplasmic reticulum ATPase
D HCAG_08733 hypothetical protein K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
B Xenophagy
C Cargo receptors
D HCAG_03477 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Other xenophagy associated proteins
B ER-phagy
C ER-phagy recepters
D HCAG_03787 hypothetical protein K12275 SEC62; translocation protein SEC62
C Other ER-phagy associated proteins
D HCAG_06060 similar to calnexin K08054 CANX; calnexin
D HCAG_00124 hypothetical protein K17278 PGRMC1_2; membrane-associated progesterone receptor component
C ER stress-related proteins
D HCAG_05805 heat shock 70 kDa protein C precursor K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
D HCAG_01136 eukaryotic translation initiation factor 2 alpha subunit K03237 EIF2S1; translation initiation factor 2 subunit 1
B Chaperone mediated autophagy (CMA)
C Selective cargos
D HCAG_03751 similar to aspartate aminotransferase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D HCAG_08678 aspartate aminotransferase K14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]
D HCAG_04910 glyceraldehyde-3-phosphate dehydrogenase K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D HCAG_07781 similar to CDC19 K00873 PK; pyruvate kinase [EC:2.7.1.40]
D HCAG_05172 deubiquitination-protection protein dph1 K04523 UBQLN; ubiquilin
C Cargo receptors
C Chaperones
D HCAG_00806 heat shock 70 kDa protein K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
D HCAG_04686 ATP-dependent molecular chaperone HSC82 K04079 HSP90A; molecular chaperone HtpG
C Co-chaperones
C Other CMA associated proteins
D HCAG_08798 translation elongation factor 1-alpha K03231 EEF1A; elongation factor 1-alpha
D HCAG_08666 carboxypeptidase Y precursor K13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]
B Other autophagy associated proteins
C RNautophagy/DNautophagy
C Micronucleophagy
D HCAG_02510 vacuolar protein 8 K08332 VAC8; vacuolar protein 8
C Midbophagy
D HCAG_03477 hypothetical protein K17987 NBR1; next to BRCA1 gene 1 protein
C Glycophagy
C TRIM-directed selective autophagy
C ER-mitochondria tethering complex
D HCAG_02485 hypothetical protein K06030 MFN2; mitofusin 2 [EC:3.6.5.-]
C mTORC1 complex
D HCAG_08094 hypothetical protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D HCAG_06154 WD-repeat protein pop3 K08266 MLST8; target of rapamycin complex subunit LST8
D HCAG_05366 WD-repeat protein mip1 K07204 RAPTOR; regulatory associated protein of mTOR
C mTORC2 complex
D HCAG_08094 hypothetical protein K07203 MTOR; serine/threonine-protein kinase mTOR [EC:2.7.11.1]
D HCAG_06154 WD-repeat protein pop3 K08266 MLST8; target of rapamycin complex subunit LST8
D HCAG_03888 hypothetical protein K20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1/AVO1
D HCAG_08070 hypothetical protein K08267 RICTOR; rapamycin-insensitive companion of mTOR
C SEACIT/GATOR1 complex
D HCAG_00937 hypothetical protein K20404 DEPDC5; SEA/GATOR complex protein SEA1/DEPDC5
D HCAG_03601 hypothetical protein K20405 NPRL2; nitrogen permease regulator 2
D HCAG_01451 hypothetical protein K20406 NPRL3; nitrogen permease regulator 3
C SEACAT/GATOR2 complex
D HCAG_04554 hypothetical protein K20408 WDR24; SEA/GATOR complex protein SEA2/WDR24
D HCAG_03162 hypothetical protein K20409 WDR59; SEA/GATOR complex protein SEA3/WDR59
D HCAG_06286 hypothetical protein K20407 MIOS; SEA/GATOR complex protein SEA4/MIOS
D HCAG_07102 hypothetical protein K14299 SEH1; nucleoporin SEH1
D HCAG_08938 protein transport protein SEC13 K14004 SEC13; protein transport protein SEC13
C KICSTOR complex
C Rab GTPases
D HCAG_06941 GTP-binding protein ypt1 K07874 RAB1A; Ras-related protein Rab-1A
D HCAG_07659 GTP-binding protein SAS1 K07901 RAB8A; Ras-related protein Rab-8A
C Rab associated proteins
C Others
D HCAG_04969 serine/threonine protein phosphatase PP2A catalytic subunit K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
D HCAG_02660 similar to TapA protein K17606 IGBP1; immunoglobulin-binding protein 1
D HCAG_02481 hypothetical protein K21249 UVRAG; UV radiation resistance-associated gene protein
D HCAG_02037 hypothetical protein K06902 UMF1; MFS transporter, UMF1 family
D HCAG_04234 hypothetical protein K14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)
D HCAG_00718 hypothetical protein K22991 WDR45; WD repeat-containing protein 45
D HCAG_04315 hypothetical protein K23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21
#
AOthers
B NADPH oxidases (Nox) and associated proteins
C NADPH oxidases
D HCAG_05182 similar to NADPH oxidase K08008 NOX1; NADPH oxidase 1
D HCAG_01252 similar to NADPH oxidase isoform 2 K21421 NOX2; NADPH oxidase 2 [EC:1.-.-.-]
C Nox associated proteins
D HCAG_01183 protein rho2 K04392 RAC1; Ras-related C3 botulinum toxin substrate 1
B Actin-binding proteins
C Myosins
D HCAG_06165 myosin-1 K10356 MYO1; myosin I
D HCAG_03105 similar to myosin 5B K10357 MYO5; myosin V
C Arp2/3 complex
D HCAG_04115 similar to Arp2/3 complex chain sop2 K05757 ARPC1A_B; actin related protein 2/3 complex, subunit 1A/1B
D HCAG_04706 ARP2/3 complex 34 kDa subunit K05758 ARPC2; actin related protein 2/3 complex, subunit 2
D HCAG_04901 hypothetical protein K05756 ARPC3; actin related protein 2/3 complex, subunit 3
D HCAG_03174 ARP2/3 complex 20 kDa subunit K05755 ARPC4; actin related protein 2/3 complex, subunit 4
D HCAG_06610 hypothetical protein K05754 ARPC5; actin related protein 2/3 complex, subunit 5
D HCAG_08430 actin K17260 ACTR2; actin-related protein 2
D HCAG_00848 Arp2/3 complex subunit K18584 ACTR3; actin-related protein 3
C Nucleation-promoting factors (NPFs)
D HCAG_03222 hypothetical protein K23612 WASL; neural Wiskott-Aldrich syndrome protein
D HCAG_01880 hypothetical protein K20520 DBNL; drebrin-like protein
D HCAG_06416 hypothetical protein K20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1
D HCAG_01146 similar to RVS167 protein K12562 AMPH; amphiphysin
D HCAG_02733 hypothetical protein K20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1
D HCAG_08090 hypothetical protein K20521 BBC1; myosin tail region-interacting protein MTI1
D HCAG_04338 hypothetical protein K20522 LSB1_2; LAS seventeen-binding protein 1/2
D HCAG_09029 hypothetical protein K20523 SH3YL1; SH3 domain-containing YSC84-like protein 1
D HCAG_05731 hypothetical protein K20524 LSB5; LAS seventeen-binding protein 5
D HCAG_05972 hypothetical protein K13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]
C Others
D HCAG_07506 hypothetical protein K05759 PFN; profilin
D HCAG_06960 hypothetical protein K05765 CFL; cofilin
D HCAG_00771 hypothetical protein K17261 CAP1_2; adenylyl cyclase-associated protein
D HCAG_08619 kinesin heavy chain K10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]
D HCAG_07039 hypothetical protein K20526 TAGLN; transgelin
B Mucins
C Membrane bound mucins
C Secretory mucins
B MARVEL domain-containing proteins
B Specific organelles associated proteins
C Melanosome
C Auto phagosome
C Lipid droplets
D HCAG_00191 hypothetical protein K28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]
C Mitochondrion
B Rho GTPase associated proteins
C Rho GTPase-activating proteins
D HCAG_01182 hypothetical protein K20643 RGD1; Rho GTPase-activating protein RGD1
D HCAG_04097 hypothetical protein K08773 RALBP1; RalA-binding protein 1
C Rho guanine nucleotide exchange factors (GEFs)
D HCAG_06352 hypothetical protein K20705 DNMBP; dynamin-binding protein
D HCAG_06041 hypothetical protein K05727 DOCK3; dedicator of cytokinesis protein 3
D HCAG_07702 hypothetical protein K27817 RAP1GDS1; Rap1 GTPase-GDP dissociation stimulator 1
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 6, 2025