+E Replication protein KO
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DNA Replication Proteins - Alkalihalobacillus sp. LMS39
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
C GINS complex
C Other initiation factors
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
C DNA polymerase epsilon complex
C DNA polymerase delta complex
C DNA polymerase gamma complex (mitochondrial)
C RPA (replication protein A)
C RFC (replication factor C)
C RNase H
D MM271_02795 ribonuclease H family protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D MM271_12930 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D MM271_15495 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
C Other elongation factors
B DNA Replication Termination Factors
C DNA methylation enzymes
D MM271_05605 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MM271_05610 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MM271_05620 dcm; DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D MM271_05645 DNA cytosine methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D Dyskerin complex
C Telomerase complex (fungi)
D Sm core complex
C ELG1-RFC complex
C MRN complex
C Other termination factors
B DNA Topoisomerases
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
D MM271_08385 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D MM271_21020 HU family DNA-binding protein K03530 hupB; DNA-binding protein HU-beta
D MM271_00005 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D MM271_23630 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D MM271_10845 ATP-binding protein K02315 dnaC; DNA replication protein DnaC
D MM271_08795 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D MM271_19770 replication initiation and membrane attachment family protein K03346 dnaB; replication initiation and membrane attachment protein
D MM271_19765 dnaI; primosomal protein DnaI K11144 dnaI; primosomal protein DnaI
D MM271_23655 ssb; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
E MM271_19895 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MM271_16465 PolC-type DNA polymerase III K03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]
E MM271_00010 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MM271_08515 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MM271_00195 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MM271_06205 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MM271_22500 3'-5' exonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MM271_23005 3'-5' exoribonuclease K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MM271_00135 dnaX; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D RNase H
E MM271_02795 ribonuclease H family protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E MM271_12930 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E MM271_15495 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E MM271_16750 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D Other elongation factors
E MM271_19810 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MM271_02155 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E MM271_15040 flap endonuclease K23786 exoA; 5'-3' exonuclease [EC:3.1.11.-]
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E MM271_02795 ribonuclease H family protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E MM271_12930 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E MM271_15495 reverse transcriptase-like protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E MM271_16750 ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
D MM271_13205 DNA adenine methylase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
C Prevention of re-replication factors
B DNA Topoisomerases
C MM271_00035 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
C MM271_00030 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
C MM271_12880 parC; DNA topoisomerase IV subunit A K02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]
C MM271_12885 parE; DNA topoisomerase IV subunit B K02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]
C MM271_16710 topA; type I DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C MM271_15115 DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
C MM271_18470 DNA topoisomerase III K03169 topB; DNA topoisomerase III [EC:5.6.2.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 27, 2025