+F Repair protein KO
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DNA Repair and Recombination Proteins - Advenella mimigardefordensis
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MIM_c36300 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E MIM_c16170 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MIM_c09090 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MIM_c24190 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D MIM_c09280 putative NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MIM_c15940 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D MIM_c36300 ogt; methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D MIM_c11120 ada; bifunctional transcriptional activator/DNA repair enzyme Ada K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D MIM_c28320 putative methyltransferase K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D MIM_c17080 alkB; alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E MIM_c16170 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E MIM_c24320 uracil-DNA glycosylase family 4 domain-containing protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E MIM_c19780 putative glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MIM_c12590 DNA-3-methyladenine glycosylase K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E MIM_c09090 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E MIM_c40250 DNA-3-methyladenine glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E MIM_c32480 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E MIM_c24190 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E MIM_c08890 xth; exodeoxyribonuclease 3 K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E MIM_c21310 xthA; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E MIM_c18690 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E MIM_c24280 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E MIM_c14740 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E MIM_c26860 uvrA1; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E MIM_c38620 uvrA2; uvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E MIM_c18190 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E MIM_c16450 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E MIM_c02880 putative DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MIM_c16040 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MIM_c14740 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E MIM_c24280 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F MIM_c40630 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F MIM_c40620 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F MIM_c38940 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F MIM_c18860 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F MIM_c24400 mfd; transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E MIM_c12310 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E MIM_c26300 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E MIM_c15830 xseA; exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E MIM_c14790 putative exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E MIM_c15180 dnaE1; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E MIM_c00020 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E MIM_c23740 putative DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E MIM_c14680 holA; DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E MIM_c19610 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E MIM_c28660 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MIM_c16120 putative excinuclease Cho K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MIM_c24440 putative DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E MIM_c26140 dnaX; DNA polymerase III subunit tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E MIM_c24280 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E MIM_c02880 putative DNA helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MIM_c16040 uvrD; DNA helicase II K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E MIM_c36410 ssb1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
E MIM_c10520 putative single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E MIM_c38600 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E MIM_c18220 recA; protein RecA K03553 recA; recombination protein RecA
E MIM_c10190 ruvA; holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MIM_c10150 ruvB; holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MIM_c10200 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E MIM_c07610 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E MIM_c14840 priB; primosomal replication protein n K02686 priB; primosomal replication protein N
E MIM_c15700 sbcC; nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E MIM_c15690 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E MIM_c18220 recA; protein RecA K03553 recA; recombination protein RecA
E MIM_c15030 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E MIM_c19010 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E MIM_c18690 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E MIM_c23790 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E MIM_c26120 recR; recombination protein RecR K06187 recR; recombination protein RecR
E MIM_c11500 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E MIM_c18210 rdgC; recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E MIM_c10190 ruvA; holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E MIM_c10150 ruvB; holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E MIM_c10200 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E MIM_c15700 sbcC; nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E MIM_c15690 sbcD; nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
E MIM_c23300 putative ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E MIM_c30330 putative Ku-type ATP-dependent DNA helicase K10979 ku; DNA end-binding protein Ku
E MIM_c30320 putative DNA ligase D K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F MIM_c22860 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F MIM_c00030 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
E Supressor
F MIM_c15620 putative DNA-binding protein Hu-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F MIM_c18690 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F MIM_c23790 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F MIM_c26120 recR; recombination protein RecR K06187 recR; recombination protein RecR
F MIM_c24280 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F MIM_c10220 putative FIS-like DNA-binding protein K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F MIM_c21800 ihfA; integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F MIM_c22780 ihfB; integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F MIM_c10100 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F MIM_c26860 uvrA1; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F MIM_c38620 uvrA2; uvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F MIM_c18190 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D MIM_c21690 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D MIM_24p00020 umuC; protein UmuC K03502 umuC; DNA polymerase V
D MIM_c07720 umuC; protein UmuC K03502 umuC; DNA polymerase V
D MIM_24p00030 umuD; protein UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
D MIM_c07730 umuD; protein UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D MIM_c18220 recA; protein RecA K03553 recA; recombination protein RecA
D MIM_c18170 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D MIM_c11500 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D MIM_c28050 putative cell division inhibitor protein K14160 imuA; protein ImuA
D MIM_c28040 hypothetical protein K14161 imuB; protein ImuB
D MIM_c28030 dnaE2; error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D MIM_c36410 ssb1; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D MIM_c10520 putative single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MIM_c38600 ssb2; single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D MIM_c18230 recX; regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D MIM_c07620 rep; ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D MIM_c21700 putative helicase IV K03658 helD; DNA helicase IV [EC:5.6.2.4]
D MIM_c13490 putative ATP-dependent helicase K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D MIM_c09280 putative NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D MIM_c15940 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D MIM_c16580 nrdA; ribonucleoside-diphosphate reductase 1 subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D MIM_c16590 nrdB; ribonucleoside-diphosphate reductase 1 subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024