+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Amycolatopsis sp. AA4

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS D Chivosazol hybrid PKS-NRPS E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS D Difficidin PKS D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036] C Bacterial type D CU254_17290 beta-ketoacyl synthase K15314 sgcE; enediyne polyketide synthase B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS C C7-C14 cyclized polyketide type D Octaketide PKS E CU254_30580 MBL fold metallo-hydrolase K05555 actIV; cyclase [EC:4.-.-.-] E CU254_00730 MBL fold metallo-hydrolase K05555 actIV; cyclase [EC:4.-.-.-] E CU254_34460 MBL fold metallo-hydrolase K05555 actIV; cyclase [EC:4.-.-.-] D Nonaketide PKS D Decaketide PKS B Type III PKS C Plant type C Fungal type C Bacterial type D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase C Iturin family lipopeptide synthetase C Fengycin family lipopeptide synthetase C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D CU254_20490 MbtH family protein K05375 mbtH; MbtH protein D CU254_12970 MbtH family protein K05375 mbtH; MbtH protein D CU254_16025 MbtH family protein K05375 mbtH; MbtH protein D CU254_16105 MbtH family protein K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D CU254_12985 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Bacillibactin synthetase D CU254_12985 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase D CU254_12950 non-ribosomal peptide synthetase K04788 mbtB; mycobactin phenyloxazoline synthetase C Vibriobactin synthetase D CU254_12985 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Myxochelin synthetase D CU254_12985 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase D CU254_12985 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] # APolyketide tailoring proteins B Hydrolase C CU254_17295 acyl-CoA thioesterase K15315 sgcE10; enediyne core biosynthesis thioesterase B Ketoreductase C CU254_34485 hydroxylacyl-CoA dehydrogenase K05556 actVI1; ketoreductase RED1 [EC:1.1.1.-] B Oxygenase C CU254_13715 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C CU254_41355 cytochrome P450 K20420 ncsB3; 2-hydroxy-5-methyl-1-naphthoate 7-hydroxylase [EC:1.14.15.31] C CU254_27965 epoxide hydrolase K21159 sgcF; epoxide hydrolase C CU254_40120 epoxide hydrolase K21159 sgcF; epoxide hydrolase C CU254_40495 epoxide hydrolase K21159 sgcF; epoxide hydrolase C CU254_14905 epoxide hydrolase K21159 sgcF; epoxide hydrolase C CU254_17025 epoxide hydrolase K21159 sgcF; epoxide hydrolase C CU254_05320 epoxide hydrolase K21159 sgcF; epoxide hydrolase C CU254_31470 epoxide hydrolase K21159 sgcF; epoxide hydrolase C CU254_27895 FAD-dependent oxidoreductase K14672 whiEVIII; putative polyketide hydroxylase B Methylase C CU254_34420 methyltransferase K20421 ncsB1; 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase [EC:2.1.1.303] B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins B Others C CU254_26650 cyclase K14627 actVI3; dehydratase [EC:4.2.1.-] C CU254_17280 DUF1702 domain-containing protein K21161 sgcE3; enediyne biosynthesis protein E3 C CU254_17285 hypothetical protein K21162 sgcE4; enediyne biosynthesis protein E4 C CU254_17405 homocysteine S-methyltransferase family protein K21169 calE2; enediyne biosynthesis protein CalE2 C CU254_17325 hypothetical protein K21170 calE3; enediyne biosynthesis protein CalE3 C CU254_17390 cysteine desulfurase K21171 calE4; enediyne biosynthesis protein CalE4 C CU254_17395 class I SAM-dependent methyltransferase K21172 calE5; enediyne biosynthesis protein CalE5 C CU254_17400 PLP-dependent transferase K21173 calE6; methionine gamma-lyase C CU254_17365 aminotransferase class V-fold PLP-dependent enzyme K21174 calE9; enediyne biosynthesis protein CalE9 # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase B Oxygenase B Glycosyltransferase B Aminotransferase B Others C CU254_03020 alpha-hydroxy-acid oxidizing protein K16422 hmo; 4-hydroxymandelate oxidase [EC:1.1.3.46] C CU254_14925 aspartate/glutamate racemase family protein K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: June 19, 2024