+F Repair protein KO
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DNA Repair and Recombination Proteins - Acetobacter pasteurianus IFO 3283-12
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D APA12_26690 O6-methylguanine-DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D APA12_04380 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E APA12_25430 mutY; DNA glycosylase A/G-specific MutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E APA12_25410 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D APA12_18370 acetyltransferase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D APA12_02370 hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D APA12_21030 phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D APA12_12370 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D APA12_26690 O6-methylguanine-DNA methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D APA12_04380 deoxyribodipyrimidine photolyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D APA12_21860 DNA repair protein for alkylated DNA K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E APA12_16940 phage SPO1 DNA polymerase-related protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E APA12_04010 bacteriophage-type DNA polymerase K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E APA12_25430 mutY; DNA glycosylase A/G-specific MutY K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E APA12_23560 DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E APA12_12340 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E APA12_25410 endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E APA12_10830 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E APA12_21210 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E APA12_21360 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E APA12_19090 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E APA12_21430 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E APA12_14430 uvrA; excinuclease UvrABC subunit A UvrA K03701 uvrA; excinuclease ABC subunit A
E APA12_00110 uvrA; excinuclease UvrABC subunit A UvrA K03701 uvrA; excinuclease ABC subunit A
E APA12_02400 uvrB; excinuclease UvrABC helicase subunit B UvrB K03702 uvrB; excinuclease ABC subunit B
E APA12_10850 uvrC; excinuclease UvrABC subunit C UvrC K03703 uvrC; excinuclease ABC subunit C
E APA12_10450 uvrD_rep; DNA helicase II UvrD/Rep K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E APA12_21430 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E APA12_19090 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F APA12_09270 rpoB; DNA-directed RNA polymerase beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F APA12_09280 rpoC; DNA-directed RNA polymerase beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F APA12_09550 rpoA; DNA-directed RNA polymerase alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F APA12_06440 rpoK; DNA-directed RNA polymerase omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F APA12_11060 DNA helicase transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E APA12_16730 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E APA12_07410 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E APA12_00200 exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E APA12_14920 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E APA12_19490 DNA polymerase III alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E APA12_12310 DNA polymerase III beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E APA12_07220 holC; DNA polymerase III chi subunit HolC K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E APA12_25500 DNA polymerase III delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E APA12_11460 dnaC; DNA polymerase III delta prime subunit DnaC K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E APA12_08710 DNA polymerase III exonuclease epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E APA12_20310 DNA polymerase III exonuclease epsilon subunit like protein K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E APA12_00520 DNA polymerase III gamma/tau subunit K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E APA12_19090 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E APA12_10450 uvrD_rep; DNA helicase II UvrD/Rep K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E APA12_25720 ssb; single-strand DNA binding protein Ssb K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E APA12_41760 recD_traA; DNA helicase RecD/TraA K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E APA12_00440 recA; DNA recombinase RecA K03553 recA; recombination protein RecA
E APA12_26260 ruvA; Holliday junction resolvase RusA K03550 ruvA; holliday junction DNA helicase RuvA
E APA12_26250 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E APA12_26270 ruvC; Holliday junction resolvase RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E APA12_18330 primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D RecFOR pathway proteins
E APA12_00440 recA; DNA recombinase RecA K03553 recA; recombination protein RecA
E APA12_06980 radA; DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E APA12_12300 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E APA12_11040 recG; DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E APA12_21360 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E APA12_19410 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E APA12_00540 recR; DNA recombinase RecR K06187 recR; recombination protein RecR
E APA12_19080 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E APA12_26260 ruvA; Holliday junction resolvase RusA K03550 ruvA; holliday junction DNA helicase RuvA
E APA12_26250 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E APA12_26270 ruvC; Holliday junction resolvase RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
E APA12_26100 uvrD_rep; DNA helicase II UvrD/Rep K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
E APA12_26110 nuclease K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D Other HR factor
E APA12_41090 cas1; CRISPR-associated protein Cas1 K15342 cas1; CRISP-associated protein Cas1
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F APA12_24320 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F APA12_12290 DNA gyrase subunit B Hsp90-like ATPase K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F APA12_07530 DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F APA12_40350 hu; histone-like bacterial DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F APA12_26450 hu; histone-like bacterial DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F APA12_16460 hu; histone-like bacterial DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F APA12_41420 hu; histone-like bacterial DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F APA12_21360 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F APA12_19410 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F APA12_00540 recR; DNA recombinase RecR K06187 recR; recombination protein RecR
F APA12_19090 DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F APA12_16990 integration host factor DNA-binding alpha subunit K04764 ihfA; integration host factor subunit alpha
F APA12_16930 integration host factor DNA-binding beta subunit K05788 ihfB; integration host factor subunit beta
E Supressor
F APA12_12590 recQ; DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F APA12_14430 uvrA; excinuclease UvrABC subunit A UvrA K03701 uvrA; excinuclease ABC subunit A
F APA12_00110 uvrA; excinuclease UvrABC subunit A UvrA K03701 uvrA; excinuclease ABC subunit A
F APA12_02400 uvrB; excinuclease UvrABC helicase subunit B UvrB K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D APA12_02490 impB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D APA12_00440 recA; DNA recombinase RecA K03553 recA; recombination protein RecA
D APA12_10940 lexA; transcriptional regulator LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
D APA12_19080 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D APA12_41300 hypothetical protein K14161 imuB; protein ImuB
D APA12_25720 ssb; single-strand DNA binding protein Ssb K03111 ssb; single-strand DNA-binding protein
D APA12_07310 recX; RecA repressor protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D APA12_17830 DNA helicase C2 K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
C Modulation of nucleotide pools
D APA12_18370 acetyltransferase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D APA12_02370 hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D APA12_21030 phosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D APA12_12370 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D APA12_10600 ribonucleotide-diphosphate reductase alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D APA12_02280 vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D APA12_10610 ribonucleotide-diphosphate reductase beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 19, 2024