+D GENES KO
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KEGG Orthology (KO) - Anaplasma phagocytophilum HZ
%
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A09100 Metabolism
B
B 09101 Carbohydrate metabolism
C 00010 Glycolysis / Gluconeogenesis [PATH:aph00010]
D APH_0222 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D APH_1258 fba; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APH_0624 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D APH_1349 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D APH_1321 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D APH_0389 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D APH_0695 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APH_0185 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D APH_0082 pdhA; pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D APH_1308 putative pyruvate dehydrogenase complex, E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D APH_1257 putative pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00020 Citrate cycle (TCA cycle) [PATH:aph00020]
D APH_1232 gltA; citrate synthase I K01647 CS; citrate synthase [EC:2.3.3.1]
D APH_1117 acnA; aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D APH_1166 dehydrogenase, isocitrate/isopropylmalate family K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D APH_0863 sucA; 2-oxoglutarate dehydrogenase, E1 component K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D APH_1198 sucB; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1053 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D APH_1052 sucC; succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D APH_0158 sdhA-1; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APH_0161 sdhA-2; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APH_0162 sdhB-2; succinate dehydrogenase, iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APH_0159 sdhB-1; succinate dehydrogenase, iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APH_0999 sdhC; succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D APH_0998 sdhD; succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D APH_0247 fumC; fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D APH_0629 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APH_0082 pdhA; pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D APH_1308 putative pyruvate dehydrogenase complex, E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D APH_1257 putative pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
C 00030 Pentose phosphate pathway [PATH:aph00030]
D APH_0002 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D APH_0340 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APH_0268 transketolase, thiamine diphosphate binding domain, N-terminal fragment K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APH_0492 putative transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D APH_0642 rpiB; ribose 5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D APH_1112 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D APH_1258 fba; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APH_0222 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
C 00040 Pentose and glucuronate interconversions
D APH_0002 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
C 00051 Fructose and mannose metabolism [PATH:aph00051]
D APH_0222 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D APH_1258 fba; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APH_0624 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D APH_0642 rpiB; ribose 5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
C 00052 Galactose metabolism
C 00053 Ascorbate and aldarate metabolism
C 00500 Starch and sucrose metabolism
C 00520 Amino sugar and nucleotide sugar metabolism
D APH_0745 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
C 00620 Pyruvate metabolism [PATH:aph00620]
D APH_0082 pdhA; pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D APH_1308 putative pyruvate dehydrogenase complex, E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D APH_1257 putative pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0042 malate dehydrogenase K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D APH_0629 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APH_0247 fumC; fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D APH_0185 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
C 00630 Glyoxylate and dicarboxylate metabolism [PATH:aph00630]
D APH_0629 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APH_1232 gltA; citrate synthase I K01647 CS; citrate synthase [EC:2.3.3.1]
D APH_1117 acnA; aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D APH_0364 pccA; propionyl-CoA carboxylase, alpha subunit K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D APH_0415 pccB; propionyl-CoA carboxylase, beta subunit K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
D APH_0187 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]
D APH_1061 glutamine synthetase domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_1246 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_0154 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00640 Propanoate metabolism [PATH:aph00640]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0469 putative malonyl-CoA decarboxylase K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
D APH_0364 pccA; propionyl-CoA carboxylase, alpha subunit K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D APH_0415 pccB; propionyl-CoA carboxylase, beta subunit K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
D APH_1052 sucC; succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D APH_1053 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00650 Butanoate metabolism
D APH_0158 sdhA-1; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APH_0161 sdhA-2; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APH_0162 sdhB-2; succinate dehydrogenase, iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APH_0159 sdhB-1; succinate dehydrogenase, iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APH_0999 sdhC; succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D APH_0998 sdhD; succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit
C 00660 C5-Branched dibasic acid metabolism
D APH_1052 sucC; succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D APH_1053 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
C 00562 Inositol phosphate metabolism [PATH:aph00562]
D APH_0548 putative inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
D APH_0624 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
B
B 09102 Energy metabolism
C 00190 Oxidative phosphorylation [PATH:aph00190]
D APH_0519 nuoA; NADH dehydrogenase I, A subunit K00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]
D APH_0520 nuoB; NADH dehydrogenase I, B subunit K00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]
D APH_0511 NADH dehydrogenase I, C subunit, truncated K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D APH_0521 nuoC; NADH dehydrogenase I, C subunit K00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]
D APH_0732 nuoD; NADH dehydrogenase I, D subunit K00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]
D APH_0731 nuoE; NADH dehydrogenase I, E subunit K00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]
D APH_0434 nuoF; NADH dehydrogenase I, F subunit K00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]
D APH_0712 nuoG; NADH-quinone oxidoreductase, chain G K00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]
D APH_0711 nuoH; NADH dehydrogenase I, H subunit K00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]
D APH_0801 nuoI; NADH dehydrogenase I, I subunit K00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]
D APH_0435 nuoJ; NADH dehydrogenase I, J subunit K00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]
D APH_0436 nuoK; NADH dehydrogenase I, K subunit K00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]
D APH_0437 nuoL; NADH dehydrogenase I, L subunit K00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]
D APH_0438 nuoM; NADH dehydrogenase I, M subunit K00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]
D APH_0439 nuoN; NADH dehydrogenase I, N subunit K00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]
D APH_0158 sdhA-1; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APH_0161 sdhA-2; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APH_0162 sdhB-2; succinate dehydrogenase, iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APH_0159 sdhB-1; succinate dehydrogenase, iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APH_0999 sdhC; succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D APH_0998 sdhD; succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D APH_0401 petA; ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D APH_0402 petB; ubiquinol-cytochrome c reductase, cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D APH_0403 petC; ubiquinol-cytochrome c reductase, cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D APH_1086 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D APH_0019 cytochrome c oxidase, subunit III K02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]
D APH_1085 ctaD; cytochrome c oxidase, subunit I K02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]
D APH_1084 cytochrome c oxidase, subunit II K02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]
D APH_1150 ctaG; cytochrome c oxidase assembly protein CtaG K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D APH_0123 putative cytochrome oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D APH_0180 cycM; cytochrome C, membrane-bound K08738 CYC; cytochrome c
D APH_1334 atpA; ATP synthase F1, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D APH_0494 atpD; ATP synthase F1, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D APH_0813 ATP synthase F1, gamma subunit, truncated K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D APH_0707 atpG; ATP synthase F1, gamma subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D APH_1335 atpH; ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D APH_0493 atpC; ATP synthase F1, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D APH_1192 atpB; ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D APH_1189 putative ATP synthase F0, B subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D APH_1190 putative ATP synthase F0, B' subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D APH_1191 atpE; ATP synthase F0, C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D APH_1101 ppa; inorganic pyrophosphatase K01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]
C 00195 Photosynthesis
C 00196 Photosynthesis - antenna proteins
C 00710 Carbon fixation by Calvin cycle [PATH:aph00710]
D APH_1321 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D APH_1349 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D APH_1258 fba; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APH_0222 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D APH_0340 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APH_0268 transketolase, thiamine diphosphate binding domain, N-terminal fragment K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APH_0642 rpiB; ribose 5-phosphate isomerase B K01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]
D APH_0624 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
D APH_0002 rpe; ribulose-phosphate 3-epimerase K01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]
D APH_0492 putative transaldolase K00616 TALDO1; transaldolase [EC:2.2.1.2]
D APH_0185 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D APH_0042 malate dehydrogenase K00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]
D APH_0629 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00720 Other carbon fixation pathways [PATH:aph00720]
D APH_0185 ppdK; pyruvate, phosphate dikinase K01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]
D APH_0629 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APH_0247 fumC; fumarate hydratase, class II K01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]
D APH_0158 sdhA-1; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APH_0161 sdhA-2; succinate dehydrogenase, flavoprotein subunit K00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]
D APH_0162 sdhB-2; succinate dehydrogenase, iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APH_0159 sdhB-1; succinate dehydrogenase, iron-sulfur protein K00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]
D APH_0999 sdhC; succinate dehydrogenase, cytochrome b556 subunit K00241 sdhC; succinate dehydrogenase cytochrome b subunit
D APH_0998 sdhD; succinate dehydrogenase, hydrophobic membrane anchor protein K00242 sdhD; succinate dehydrogenase membrane anchor subunit
D APH_1053 sucD; succinyl-CoA synthetase, alpha subunit K01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]
D APH_1052 sucC; succinyl-CoA synthetase, beta subunit K01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]
D APH_1166 dehydrogenase, isocitrate/isopropylmalate family K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
D APH_1117 acnA; aconitate hydratase 1 K01681 ACO; aconitate hydratase [EC:4.2.1.3]
D APH_0175 folD; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
C 00680 Methane metabolism [PATH:aph00680]
D APH_0154 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APH_0695 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APH_0629 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
D APH_1258 fba; fructose-bisphosphate aldolase, class I K11645 fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]
D APH_0222 glpX; fructose-1,6-bisphosphatase, class II K02446 glpX; fructose-1,6-bisphosphatase II [EC:3.1.3.11]
D APH_0389 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
C 00910 Nitrogen metabolism [PATH:aph00910]
D APH_0553 NAD-glutamate dehydrogenase family protein K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D APH_1061 glutamine synthetase domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_1246 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
C 00920 Sulfur metabolism
B
B 09103 Lipid metabolism
C 00061 Fatty acid biosynthesis [PATH:aph00061]
D APH_0929 putative acyl carrier protein K02078 acpP; acyl carrier protein
D APH_0092 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D APH_0317 fabH; 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D APH_0930 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D APH_0668 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APH_1208 fabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D APH_0473 fabI; enoyl-(acyl-carrier-protein) reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D APH_1048 fabK; enoyl-(acyl-carrier-protein) reductase II K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
C 00062 Fatty acid elongation
C 00071 Fatty acid degradation
C 00073 Cutin, suberine and wax biosynthesis
C 00100 Steroid biosynthesis
C 00120 Primary bile acid biosynthesis
C 00121 Secondary bile acid biosynthesis
C 00140 Steroid hormone biosynthesis
C 00561 Glycerolipid metabolism [PATH:aph00561]
D APH_0316 plsX; fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D APH_0017 conserved hypothetical protein TIGR00023 K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D APH_1373 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 00564 Glycerophospholipid metabolism [PATH:aph00564]
D APH_0198 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) K00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]
D APH_0017 conserved hypothetical protein TIGR00023 K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D APH_1373 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
D APH_0113 putative phosphatidate cytidylyltransferase K00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]
D APH_0543 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
D APH_0544 putative phosphatidylserine decarboxylase K01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]
D APH_0974 pgpA; phosphatidylglycerophosphatase A K01095 pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]
D APH_1206 pgsA; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase K08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]
D APH_1193 AraM domain protein K00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]
C 00565 Ether lipid metabolism
C 00600 Sphingolipid metabolism
C 00590 Arachidonic acid metabolism
C 00591 Linoleic acid metabolism
C 00592 alpha-Linolenic acid metabolism
C 01040 Biosynthesis of unsaturated fatty acids
B
B 09104 Nucleotide metabolism
C 00230 Purine metabolism [PATH:aph00230]
D APH_1112 prsA; ribose-phosphate pyrophosphokinase K00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]
D APH_1300 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D APH_1088 purD; phosphoribosylamine--glycine ligase K01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]
D APH_0230 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D APH_0087 putative phosphoribosylglycinamide formyltransferase, truncated K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D APH_0225 putative phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D APH_0213 putative phosphoribosylformylglycinamidine synthase II K23270 purSL; phosphoribosylformylglycinamidine synthase subunit PurSL [EC:6.3.5.3]
D APH_0202 purM-1; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D APH_0210 purM-2; phosphoribosylformylglycinamidine cyclo-ligase K01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]
D APH_1119 purK; phosphoribosylaminoimidazole carboxylase, ATPase subunit K01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]
D APH_1279 purE; phosphoribosylaminoimidazole carboxylase, catalytic subunit K01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]
D APH_0119 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]
D APH_0867 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D APH_1207 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D APH_0524 surE; stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D APH_0088 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D APH_1217 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D APH_1233 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D APH_0170 gmk; guanylate kinase K00942 gmk; guanylate kinase [EC:2.7.4.8]
D APH_0147 guanylate kinase, truncated K00942 gmk; guanylate kinase [EC:2.7.4.8]
D APH_0331 nrdA; ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D APH_0560 nrdB; ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D APH_0336 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D APH_0300 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00240 Pyrimidine metabolism [PATH:aph00240]
D APH_0249 carB; carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D APH_0381 carA; carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D APH_0503 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D APH_0245 pyrC; dihydroorotase, multifunctional complex type K01465 URA4; dihydroorotase [EC:3.5.2.3]
D APH_1013 pyrD; dihydroorotate dehydrogenase K00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]
D APH_1173 pyrE; orotate phosphoribosyltransferase K00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]
D APH_0527 pyrF; orotidine 5'-phosphate decarboxylase K01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]
D APH_0111 pyrH; uridylate kinase K09903 pyrH; uridylate kinase [EC:2.7.4.22]
D APH_1217 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D APH_0396 maf; maf protein K06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]
D APH_0038 pyrG; CTP synthase K01937 pyrG; CTP synthase [EC:6.3.4.2]
D APH_0274 cmkB; cytidylate monophosphate kinase K00945 cmk; CMP/dCMP kinase [EC:2.7.4.25]
D APH_0524 surE; stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D APH_0130 putative deoxycytidine triphosphate deaminase K01494 dcd; dCTP deaminase [EC:3.5.4.13]
D APH_0331 nrdA; ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D APH_0560 nrdB; ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D APH_0093 tmk; thymidylate kinase K00943 tmk; dTMP kinase [EC:2.7.4.9]
D APH_0379 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D APH_0163 thyX; thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
B
B 09105 Amino acid metabolism
C 00250 Alanine, aspartate and glutamate metabolism [PATH:aph00250]
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APH_0336 purA; adenylosuccinate synthetase K01939 purA; adenylosuccinate synthase [EC:6.3.4.4]
D APH_0867 purB; adenylosuccinate lyase K01756 purB; adenylosuccinate lyase [EC:4.3.2.2]
D APH_0503 pyrB; aspartate carbamoyltransferase K00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]
D APH_0553 NAD-glutamate dehydrogenase family protein K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D APH_0669 putA; proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D APH_1061 glutamine synthetase domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_1246 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_0249 carB; carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D APH_0381 carA; carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D APH_0225 putative phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D APH_1300 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C 00260 Glycine, serine and threonine metabolism [PATH:aph00260]
D APH_1346 putative aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D APH_0154 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APH_0389 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]
D APH_1243 hemA; 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0543 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase K17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]
C 00270 Cysteine and methionine metabolism [PATH:aph00270]
D APH_0058 S-adenosylmethionine synthetase, truncated K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D APH_0007 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D APH_1346 putative aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D APH_1231 gshA; glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2]
D APH_0193 gshB; glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3]
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APH_0629 mdh; malate dehydrogenase, NAD-dependent K00024 mdh; malate dehydrogenase [EC:1.1.1.37]
C 00280 Valine, leucine and isoleucine degradation [PATH:aph00280]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0364 pccA; propionyl-CoA carboxylase, alpha subunit K01965 PCCA; propionyl-CoA carboxylase alpha subunit [EC:6.4.1.3]
D APH_0415 pccB; propionyl-CoA carboxylase, beta subunit K01966 PCCB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15]
C 00290 Valine, leucine and isoleucine biosynthesis
C 00300 Lysine biosynthesis [PATH:aph00300]
D APH_1346 putative aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
D APH_0945 argD; acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00310 Lysine degradation [PATH:aph00310]
D APH_1198 sucB; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00220 Arginine biosynthesis [PATH:aph00220]
D APH_0225 putative phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
D APH_1061 glutamine synthetase domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_1246 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_0249 carB; carbamoyl-phosphate synthase, large subunit K01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]
D APH_0381 carA; carbamoyl-phosphate synthase, small subunit K01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]
D APH_0553 NAD-glutamate dehydrogenase family protein K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APH_0422 argB; acetylglutamate kinase K00930 argB; acetylglutamate kinase [EC:2.7.2.8]
D APH_0945 argD; acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
C 00330 Arginine and proline metabolism [PATH:aph00330]
D APH_0669 putA; proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00340 Histidine metabolism
C 00350 Tyrosine metabolism
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00360 Phenylalanine metabolism
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00380 Tryptophan metabolism
D APH_1198 sucB; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
C 00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:aph00400]
D APH_1001 putative 3-phosphoshikimate 1-carboxyvinyltransferase K00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
B
B 09106 Metabolism of other amino acids
C 00410 beta-Alanine metabolism
D APH_0469 putative malonyl-CoA decarboxylase K01578 MLYCD; malonyl-CoA decarboxylase [EC:4.1.1.9]
C 00430 Taurine and hypotaurine metabolism
D APH_0553 NAD-glutamate dehydrogenase family protein K15371 GDH2; glutamate dehydrogenase [EC:1.4.1.2]
C 00440 Phosphonate and phosphinate metabolism
D APH_1062 metallo-beta-lactamase family protein K06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]
C 00450 Selenocompound metabolism [PATH:aph00450]
D APH_0734 pyridine nucleotide-disulfide oxidoreductase family protein K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D APH_0658 trxB; thioredoxin-disulfide reductase K00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]
D APH_1079 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
C 00460 Cyanoamino acid metabolism
D APH_0154 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
C 00470 D-Amino acid metabolism
D APH_0225 putative phosphoribosylformylglycinamidine synthase I K23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ / glutaminase [EC:6.3.5.3 3.5.1.2]
C 00480 Glutathione metabolism [PATH:aph00480]
D APH_1231 gshA; glutamate--cysteine ligase K01919 gshA; glutamate--cysteine ligase [EC:6.3.2.2]
D APH_0193 gshB; glutathione synthetase K01920 gshB; glutathione synthase [EC:6.3.2.3]
D APH_0231 pepA; cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D APH_1166 dehydrogenase, isocitrate/isopropylmalate family K00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]
B
B 09107 Glycan biosynthesis and metabolism
C 00510 N-Glycan biosynthesis
C 00513 Various types of N-glycan biosynthesis
C 00512 Mucin type O-glycan biosynthesis
C 00515 Mannose type O-glycan biosynthesis
C 00514 Other types of O-glycan biosynthesis
C 00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
C 00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
C 00533 Glycosaminoglycan biosynthesis - keratan sulfate
C 00531 Glycosaminoglycan degradation
C 00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
C 00601 Glycosphingolipid biosynthesis - lacto and neolacto series
C 00603 Glycosphingolipid biosynthesis - globo and isoglobo series
C 00604 Glycosphingolipid biosynthesis - ganglio series
C 00511 Other glycan degradation
C 00540 Lipopolysaccharide biosynthesis
C 00542 O-Antigen repeat unit biosynthesis
C 00541 O-Antigen nucleotide sugar biosynthesis
C 00550 Peptidoglycan biosynthesis [PATH:aph00550]
D APH_0745 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D APH_1214 D-alanyl-D-alanine carboxypeptidase family protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C 00552 Teichoic acid biosynthesis
C 00571 Lipoarabinomannan (LAM) biosynthesis
C 00572 Arabinogalactan biosynthesis - Mycobacterium
C 00543 Exopolysaccharide biosynthesis
B
B 09108 Metabolism of cofactors and vitamins
C 00730 Thiamine metabolism [PATH:aph00730]
D APH_0600 thiC; thiamine biosynthesis protein ThiC K03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]
D APH_0993 thiD; phosphomethylpyrimidine kinase K00941 thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]
D APH_0674 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0673 rrf2 family protein/cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0325 oxidoreductase, FAD-binding protein K03153 thiO; glycine oxidase [EC:1.4.3.19]
D APH_0070 thiamin biosynthesis ThiG K03149 thiG; thiazole synthase [EC:2.8.1.10]
D APH_0960 thiE; thiamine-phosphate pyrophosphorylase K00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]
D APH_0735 thiL; thiamine-monophosphate kinase K00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]
D APH_0300 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
C 00740 Riboflavin metabolism [PATH:aph00740]
D APH_1314 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D APH_1319 GTP cyclohydrolase II, degenerate K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D APH_0037 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D APH_1332 ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase K02858 ribB; 3,4-dihydroxy 2-butanone 4-phosphate synthase [EC:4.1.99.12]
D APH_0539 ribH; 6,7-dimethyl-8-ribityllumazine synthase K00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]
D APH_0106 ribE; riboflavin synthase, alpha subunit K00793 ribE; riboflavin synthase [EC:2.5.1.9]
D APH_1161 ribF; riboflavin biosynthesis protein RibF K11753 ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]
D APH_0749 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00750 Vitamin B6 metabolism [PATH:aph00750]
D APH_1008 pdxH; pyridoxamine 5'-phosphate oxidase K00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]
D APH_0790 pdxJ; pyridoxal phosphate biosynthesis protein PdxJ K03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]
C 00760 Nicotinate and nicotinamide metabolism [PATH:aph00760]
D APH_0026 nadA; quinolinate synthetase complex, A subunit K03517 nadA; quinolinate synthase [EC:2.5.1.72]
D APH_0016 nadC; nicotinate-nucleotide pyrophosphorylase K00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]
D APH_0524 surE; stationary-phase survival protein SurE K03787 surE; 5'/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]
D APH_0791 putative nicotinate (nicotinamide) nucleotide adenylyltransferase K00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]
D APH_0852 putative glutamine-dependent NAD(+) synthetase K01916 nadE; NAD+ synthase [EC:6.3.1.5]
D APH_1265 competence/damage-inducible protein CinA C-terminal domain protein K03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]
D APH_0089 ppnK; ATP-NAD kinase K00858 ppnK; NAD+ kinase [EC:2.7.1.23]
C 00770 Pantothenate and CoA biosynthesis [PATH:aph00770]
D APH_1014 putative transcriptional activator, Baf family K03525 coaX; type III pantothenate kinase [EC:2.7.1.33]
D APH_0246 DNA / pantothenate metabolism flavoprotein family protein K21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]
D APH_0650 coaD; pantetheine-phosphate adenylyltransferase K00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]
D APH_0780 coaE; dephospho-CoA kinase K00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]
D APH_0646 acpS; holo-(acyl-carrier-protein) synthase K00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]
C 00780 Biotin metabolism [PATH:aph00780]
D APH_0025 putative biotin synthesis protein BioC K02169 bioC; malonyl-CoA O-methyltransferase [EC:2.1.1.197]
D APH_0930 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D APH_0668 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APH_1208 fabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D APH_0473 fabI; enoyl-(acyl-carrier-protein) reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D APH_0979 8-amino-7-oxononanoate synthase, truncated K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D APH_1016 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D APH_0482 bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
D APH_1228 bioD; dethiobiotin synthetase K01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]
D APH_0218 bioB; biotin synthase K01012 bioB; biotin synthase [EC:2.8.1.6]
D APH_0876 biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D APH_0856 putative biotin--acetyl-CoA-carboxylase ligase, truncated K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
C 00785 Lipoic acid metabolism [PATH:aph00785]
D APH_0243 lipB; lipoate-protein ligase B K03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]
D APH_0367 lipA; lipoic acid synthetase K03644 lipA; lipoyl synthase [EC:2.8.1.8]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0082 pdhA; pyruvate dehydrogenase complex, E1 component, pyruvate dehydrogenase alpha subunit K00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
D APH_1308 putative pyruvate dehydrogenase complex, E1 component, beta subunit K00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
D APH_1257 putative pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase K00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]
D APH_0863 sucA; 2-oxoglutarate dehydrogenase, E1 component K00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]
D APH_1198 sucB; 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase K00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]
C 00790 Folate biosynthesis [PATH:aph00790]
D APH_0814 GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D APH_0706 folE; GTP cyclohydrolase I K01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]
D APH_0628 folB; dihydroneopterin aldolase K01633 folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]
D APH_0212 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]
D APH_0254 folP; dihydropteroate synthase K00796 folP; dihydropteroate synthase [EC:2.5.1.15]
D APH_0747 folC; folylpolyglutamate synthase K11754 folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
D APH_1314 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D APH_1319 GTP cyclohydrolase II, degenerate K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
C 00670 One carbon pool by folate [PATH:aph00670]
D APH_0175 folD; methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase K01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]
D APH_0154 glyA; serine hydroxymethyltransferase K00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]
D APH_0230 purN; phosphoribosylglycinamide formyltransferase K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D APH_0087 putative phosphoribosylglycinamide formyltransferase, truncated K11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]
D APH_1207 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D APH_0965 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D APH_0163 thyX; thymidylate synthase, flavin-dependent K03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]
D APH_0693 5-formyltetrahydrofolate cyclo-ligase family protein K01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]
C 00830 Retinol metabolism
C 00860 Porphyrin metabolism [PATH:aph00860]
D APH_1243 hemA; 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D APH_0072 gltX-1; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_0408 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_0851 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D APH_0746 hemC; porphobilinogen deaminase K01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]
D APH_0354 conserved hypothetical protein K01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]
D APH_0020 hemE; uroporphyrinogen decarboxylase K01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]
D APH_0423 hemF; coproporphyrinogen III oxidase, aerobic K00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]
D APH_1307 conserved hypothetical protein K08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-]
D APH_0263 hemH; ferrochelatase K01772 hemH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]
D APH_1086 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D APH_0123 putative cytochrome oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
C 00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:aph00130]
D APH_0310 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D APH_1360 ubiD; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]
D APH_0749 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D APH_0606 ubiG; 3-demethylubiquinone-9 3-methyltransferase K00568 ubiG; 2-polyprenyl-6-hydroxyphenyl methylase / 3-demethylubiquinone-9 3-methyltransferase [EC:2.1.1.222 2.1.1.64]
D APH_0009 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family K03185 ubiH; 2-octaprenyl-6-methoxyphenol hydroxylase [EC:1.14.13.-]
D APH_1075 ubiE; ubiquinone/menaquinone biosynthesis methyltransferase UbiE K03183 ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]
D APH_0911 Coq7 family protein K06134 COQ7; 3-demethoxyubiquinol 3-hydroxylase [EC:1.14.99.60]
B
B 09109 Metabolism of terpenoids and polyketides
C 00900 Terpenoid backbone biosynthesis [PATH:aph00900]
D APH_0440 dxr; 1-deoxy-D-xylulose 5-phosphate reductoisomerase K00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]
D APH_1277 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]
D APH_0574 ispE; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase K00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]
D APH_1276 ispF; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase K01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]
D APH_0442 ispG; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase K03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]
D APH_0380 ispH; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase K03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]
D APH_0749 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
D APH_0329 ispA; geranyltranstransferase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D APH_1247 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
C 00902 Monoterpenoid biosynthesis
C 00909 Sesquiterpenoid and triterpenoid biosynthesis
C 00904 Diterpenoid biosynthesis
C 00906 Carotenoid biosynthesis
C 00905 Brassinosteroid biosynthesis
C 00981 Insect hormone biosynthesis
C 00908 Zeatin biosynthesis
C 00903 Limonene degradation
C 00907 Pinene, camphor and geraniol degradation
C 01052 Type I polyketide structures
C 00522 Biosynthesis of 12-, 14- and 16-membered macrolides
C 01051 Biosynthesis of ansamycins
D APH_0340 tkt; transketolase K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
D APH_0268 transketolase, thiamine diphosphate binding domain, N-terminal fragment K00615 E2.2.1.1; transketolase [EC:2.2.1.1]
C 01059 Biosynthesis of enediyne antibiotics
C 01056 Biosynthesis of type II polyketide backbone
C 01057 Biosynthesis of type II polyketide products
C 00253 Tetracycline biosynthesis
C 00523 Polyketide sugar unit biosynthesis
C 01054 Nonribosomal peptide structures
C 01053 Biosynthesis of siderophore group nonribosomal peptides
C 01055 Biosynthesis of vancomycin group antibiotics
B
B 09110 Biosynthesis of other secondary metabolites
C 00940 Phenylpropanoid biosynthesis
C 00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis
C 00941 Flavonoid biosynthesis
C 00944 Flavone and flavonol biosynthesis
C 00942 Anthocyanin biosynthesis
C 00943 Isoflavonoid biosynthesis
C 00946 Degradation of flavonoids
C 00901 Indole alkaloid biosynthesis
C 00403 Indole diterpene alkaloid biosynthesis
C 00950 Isoquinoline alkaloid biosynthesis
C 00960 Tropane, piperidine and pyridine alkaloid biosynthesis
C 00996 Biosynthesis of various alkaloids
C 00232 Caffeine metabolism
C 00965 Betalain biosynthesis
C 00966 Glucosinolate biosynthesis
C 00402 Benzoxazinoid biosynthesis
C 00311 Penicillin and cephalosporin biosynthesis
C 00332 Carbapenem biosynthesis
C 00261 Monobactam biosynthesis
D APH_1346 putative aspartate-semialdehyde dehydrogenase K00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]
C 00331 Clavulanic acid biosynthesis
C 00521 Streptomycin biosynthesis
D APH_0548 putative inositol monophosphatase K01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]
C 00524 Neomycin, kanamycin and gentamicin biosynthesis
C 00525 Acarbose and validamycin biosynthesis
C 00401 Novobiocin biosynthesis
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
C 00404 Staurosporine biosynthesis
C 00405 Phenazine biosynthesis
C 00333 Prodigiosin biosynthesis
D APH_0092 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D APH_0668 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APH_0473 fabI; enoyl-(acyl-carrier-protein) reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
C 00254 Aflatoxin biosynthesis
C 00998 Biosynthesis of various antibiotics
D APH_0929 putative acyl carrier protein K02078 acpP; acyl carrier protein
C 00999 Biosynthesis of various plant secondary metabolites
D APH_0058 S-adenosylmethionine synthetase, truncated K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
D APH_0007 metK; S-adenosylmethionine synthetase K00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]
C 00997 Biosynthesis of various other secondary metabolites
B
B 09111 Xenobiotics biodegradation and metabolism
C 00362 Benzoate degradation
C 00627 Aminobenzoate degradation
D APH_0749 ubiX; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]
C 00364 Fluorobenzoate degradation
C 00625 Chloroalkane and chloroalkene degradation
C 00361 Chlorocyclohexane and chlorobenzene degradation
C 00623 Toluene degradation
C 00622 Xylene degradation
C 00633 Nitrotoluene degradation
C 00642 Ethylbenzene degradation
C 00643 Styrene degradation
C 00791 Atrazine degradation
C 00930 Caprolactam degradation
C 00363 Bisphenol degradation
C 00621 Dioxin degradation
C 00626 Naphthalene degradation
C 00624 Polycyclic aromatic hydrocarbon degradation
C 00365 Furfural degradation
C 00984 Steroid degradation
C 00980 Metabolism of xenobiotics by cytochrome P450
C 00982 Drug metabolism - cytochrome P450
C 00983 Drug metabolism - other enzymes
B
B 09112 Not included in regular maps
C 09113 Global maps only
#
A09120 Genetic Information Processing
B
B 09121 Transcription
C 03020 RNA polymerase [PATH:aph03020]
D APH_1024 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D APH_1023 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D APH_0303 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D APH_0514 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
C 03022 Basal transcription factors
C 03040 Spliceosome
B
B 09122 Translation
C 03010 Ribosome [PATH:aph03010]
D APH_0273 rpsA; ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D APH_0397 rpsB; ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D APH_0286 rpsC; ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D APH_0989 rpsD; ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D APH_0297 rpsE; ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D APH_0151 rpsF; ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D APH_1034 rpsG; ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D APH_0294 rpsH; ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D APH_1107 rpsI; ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D APH_0279 rpsJ; ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D APH_0302 rpsK; ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D APH_1035 rpsL; ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D APH_0301 rpsM; ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D APH_0293 rpsN; ribosomal protein S14p/S29e K02954 RP-S14; small subunit ribosomal protein S14
D APH_0768 rpsO; ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D APH_0054 rpsP; ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D APH_0289 rpsQ; ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D APH_0152 rpsR; ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D APH_0284 rpsS; ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D APH_1374 rpsT; ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D APH_1051 rpsU; ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D APH_1027 rplA; ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D APH_0283 rplB; ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D APH_0280 rplC; ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D APH_0281 rplD; ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D APH_0292 rplE; ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D APH_0295 rplF; ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D APH_1025 rplL; ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D APH_0153 rplI; ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D APH_1026 rplJ; ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D APH_1028 rplK; ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D APH_1108 rplM; ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D APH_0290 rplN; ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D APH_0298 rplO; ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D APH_0287 rplP; ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D APH_0304 rplQ; ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D APH_0296 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D APH_1266 rplS; ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D APH_0060 rplT; ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D APH_0697 rplU; ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D APH_0285 rplV; ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D APH_0282 rplW; ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D APH_0291 rplX; ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D APH_1302 ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 K02897 RP-L25; large subunit ribosomal protein L25
D APH_0698 rpmA; ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D APH_0359 rpmB; ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D APH_0288 rpmC; ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D APH_0090 putative 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D APH_0315 rpmF; ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D APH_0925 rpmG; ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D APH_0309 rpmH; ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D APH_0061 rpmI; ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D APH_0508 rpmJ; ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D APH_1000 rrsA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D APH_0084 rrlB; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D APH_0085 rrfC; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
C 00970 Aminoacyl-tRNA biosynthesis [PATH:aph00970]
D APH_0048 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D APH_0613 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APH_0008 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APH_1020 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APH_0368 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APH_0777 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D APH_0472 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D APH_1259 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D APH_0012 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D APH_0330 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D APH_0865 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APH_0277 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APH_0073 tRNA-His K14226 tRNA-His; tRNA His
D APH_0699 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D APH_0990 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_0495 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_0972 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_1315 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_1309 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_1245 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D APH_0973 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D APH_0639 tRNA-Met K14230 tRNA-Met; tRNA Met
D APH_0729 tRNA-Met K14230 tRNA-Met; tRNA Met
D APH_0966 tRNA-Met K14230 tRNA-Met; tRNA Met
D APH_0738 tRNA-Met K14230 tRNA-Met; tRNA Met
D APH_0649 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D APH_0498 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APH_1283 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APH_0616 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APH_0034 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APH_1181 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APH_0623 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APH_0410 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APH_1031 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D APH_0276 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D APH_0176 tRNA-Val K14237 tRNA-Val; tRNA Val
D APH_1396 tRNA-Val K14237 tRNA-Val; tRNA Val
D APH_0072 gltX-1; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_0408 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_0748 gatA; glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D APH_0470 gatB; glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D APH_1113 gatC; glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D APH_1059 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D APH_0190 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D APH_0165 glyQ-2; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D APH_0013 glyQ-1; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D APH_0014 glyS; glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D APH_1264 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D APH_0427 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D APH_0555 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D APH_1079 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D APH_0965 fmt; methionyl-tRNA formyltransferase K00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]
D APH_1224 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D APH_0534 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D APH_0796 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D APH_0607 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D APH_0700 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D APH_0647 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D APH_0120 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D APH_0059 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D APH_0305 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D APH_1244 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D APH_0035 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
C 03013 Nucleocytoplasmic transport
C 03015 mRNA surveillance pathway
C 03008 Ribosome biogenesis in eukaryotes
B
B 09123 Folding, sorting and degradation
C 03060 Protein export [PATH:aph03060]
D APH_0299 secY; preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D APH_1030 secE; preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D APH_0039 secG; preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG
D APH_1366 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D APH_1326 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D APH_1090 yajC; preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D APH_0540 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_0541 putative membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_1178 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D APH_0097 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D APH_0349 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D APH_1227 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D APH_0987 tatA; twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APH_0552 putative twin-arginine translocation protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D APH_0443 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
D APH_0802 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D APH_1160 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
C 04141 Protein processing in endoplasmic reticulum
C 04130 SNARE interactions in vesicular transport
C 04120 Ubiquitin mediated proteolysis
C 04122 Sulfur relay system [PATH:aph04122]
D APH_0674 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0673 rrf2 family protein/cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0910 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D APH_0069 thiS; thiamine biosynthesis protein ThiS K03154 thiS; sulfur carrier protein
C 03050 Proteasome
C 03018 RNA degradation [PATH:aph03018]
D APH_0345 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12]
D APH_0695 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APH_0767 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D APH_0064 rho-1; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D APH_1071 rho-2; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D APH_1036 metallo-beta-lactamase family, beta-CASP subfamily K12574 rnj; ribonuclease J [EC:3.1.-.-]
D APH_0346 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D APH_0240 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D APH_1216 polyA polymerase/tRNA nucleotidyltransferase family protein K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
B
B 09124 Replication and repair
C 03030 DNA replication [PATH:aph03030]
D APH_0730 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D APH_1003 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D APH_1348 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D APH_0783 conserved domain protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D APH_1252 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D APH_1097 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D APH_0323 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D APH_0571 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D APH_0465 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D APH_0109 rnhA; ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D APH_1022 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D APH_0138 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03410 Base excision repair [PATH:aph03410]
D APH_0897 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D APH_0411 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D APH_1371 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D APH_0471 exodeoxyribonuclease III, N-terminal truncated K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D APH_0505 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D APH_1165 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D APH_0138 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03420 Nucleotide excision repair [PATH:aph03420]
D APH_0107 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D APH_0537 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D APH_1367 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
D APH_0884 uvrC; excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
D APH_0903 helicase, UvrD/Rep family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D APH_0138 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03430 Mismatch repair [PATH:aph03430]
D APH_0857 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D APH_0939 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D APH_0903 helicase, UvrD/Rep family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D APH_1322 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D APH_0079 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D APH_1165 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D APH_0465 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D APH_1003 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D APH_1097 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D APH_1348 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D APH_1252 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D APH_0783 conserved domain protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D APH_0730 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D APH_0138 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
C 03440 Homologous recombination [PATH:aph03440]
D APH_1165 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D APH_0465 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D APH_1409 putative DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D APH_0736 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D APH_0988 recR; recombination protein RecR K06187 recR; recombination protein RecR
D APH_1354 recA; recA protein K03553 recA; recombination protein RecA
D APH_0167 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D APH_0166 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D APH_0018 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D APH_1298 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D APH_1003 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D APH_1097 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D APH_1348 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D APH_1252 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D APH_0783 conserved domain protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D APH_0730 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D APH_0356 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
C 03450 Non-homologous end-joining
C 03460 Fanconi anemia pathway
B
B 09126 Chromosome
C 03082 ATP-dependent chromatin remodeling
C 03083 Polycomb repressive complex
B
B 09125 Information processing in viruses
C 03230 Viral genome structure
C 03240 Viral replication
C 03250 Viral life cycle - HIV-1
C 03260 Virion - Human immunodeficiency virus
C 03271 Virion - Rotavirus
C 03262 Virion - Coronavirus
C 03261 Virion - Influenza virus
C 03263 Virion - Enterovirus
C 03264 Virion - Flavivirus
C 03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
C 03266 Virion - Herpesvirus
C 03268 Virion - Orthopoxvirus
C 03267 Virion - Adenovirus
C 03259 Virion - Bacteriophages T4 and T7
C 03258 Virion - Bacteriophage lambda
#
A09130 Environmental Information Processing
B
B 09131 Membrane transport
C 02010 ABC transporters [PATH:aph02010]
D APH_0051 iron-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D APH_1045 ABC transporter, permease protein K02011 afuB; iron(III) transport system permease protein
D APH_0986 ABC transporter, ATP-binding protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D APH_1394 conserved hypothetical protein K07323 mlaC; phospholipid transport system substrate-binding protein
D APH_0045 mce-related protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D APH_0003 putative ABC transporter, permease protein K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D APH_0004 ABC transporter, ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D APH_1050 putative phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D APH_1060 pstC; phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D APH_0370 pstA; phosphate ABC transporter, permease protein PtsA K02038 pstA; phosphate transport system permease protein
D APH_0313 pstB; phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D APH_0982 putative cation ABC transporter, periplasmic cation-binding protein K09815 znuA; zinc transport system substrate-binding protein
D APH_0399 ABC 3 transport family protein K09816 znuB; zinc transport system permease protein
D APH_0983 putative cation ABC transporter, ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D APH_1341 lipoprotein releasing system, transmembrane protein, LolC/E family K09808 lolC_E; lipoprotein-releasing system permease protein
D APH_0041 ABC transporter, ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D APH_0168 ccmC; heme exporter protein CcmC K02195 ccmC; heme exporter protein C
D APH_1397 putative heme exporter protein CcmB K02194 ccmB; heme exporter protein B
D APH_0125 ccmA; heme exporter protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D APH_0256 type I secretion system ATPase/hypothetical protein K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
C 02060 Phosphotransferase system (PTS)
C 03070 Bacterial secretion system [PATH:aph03070]
D APH_1110 outer membrane efflux protein K12340 tolC; outer membrane protein
D APH_1366 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D APH_1326 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D APH_1030 secE; preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D APH_0039 secG; preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG
D APH_0299 secY; preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D APH_1090 yajC; preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D APH_0540 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_0541 putative membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_1178 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D APH_1227 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D APH_0097 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D APH_0349 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D APH_0987 tatA; twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APH_0552 putative twin-arginine translocation protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D APH_0443 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
D APH_0372 virB3; type IV secretion system protein VirB3 K03198 virB3; type IV secretion system protein VirB3
D APH_0081 virB9-2; type IV secretion system protein VirB9-2 K03204 virB9; type IV secretion system protein VirB9
D APH_1405 virB9-1; type IV secretion system protein VirB9 (VirB9-1) K03204 virB9; type IV secretion system protein VirB9
D APH_0375 virB6-2; type IV secretion system protein VirB6 family (VirB6-2) K03201 virB6; type IV secretion system protein VirB6
D APH_0376 virB6-3; type IV secretion system protein VirB6 family (VirB6-3) K03201 virB6; type IV secretion system protein VirB6
D APH_0374 virB6-1; type IV secretion system protein VirB6-1 K03201 virB6; type IV secretion system protein VirB6
D APH_0430 virB8-2; type IV secretion system protein VirB8-2 K03203 virB8; type IV secretion system protein VirB8
D APH_1406 virB8-1; type IV secretion protein VirB8-1 K03203 virB8; type IV secretion system protein VirB8
D APH_1404 virB10; type IV secretion system protein VirB10 K03195 virB10; type IV secretion system protein VirB10
D APH_1129 virB4-2; type IV secretion system protein VirB4-2 K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D APH_0373 virB4-1; type IV secretion system protein VirB4 (VirB4-1) K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D APH_1403 virB11; type IV secretion system protein VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
D APH_1402 virD4; type IV secretion system protein VirD4 K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
B
B 09132 Signal transduction
C 02020 Two-component system [PATH:aph02020]
D APH_1050 putative phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D APH_1148 protease DO family protein K04771 degP; serine protease Do [EC:3.4.21.107]
D APH_0123 putative cytochrome oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D APH_0474 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D APH_1061 glutamine synthetase domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_1246 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_0136 ntrY; nitrogen regulation protein/Sensor Histidine Kinase NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D APH_0196 ntrX; Response Regulator NtrX, putative nitrogen assimilation regulatory protein K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D APH_0944 pleC; Sensor histidine kinase PleC K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
D APH_0551 pleD; Response regulator/GGDEF domain protein PleD K02488 pleD; two-component system, cell cycle response regulator [EC:2.7.7.65]
D APH_1099 ctrA; DNA-binding response regulator CtrA K13584 ctrA; two-component system, cell cycle response regulator CtrA
D APH_0401 petA; ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
D APH_0402 petB; ubiquinol-cytochrome c reductase, cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D APH_0403 petC; ubiquinol-cytochrome c reductase, cytochrome c1 K00413 CYC1; ubiquinol-cytochrome c reductase cytochrome c1 subunit
D APH_0180 cycM; cytochrome C, membrane-bound K08738 CYC; cytochrome c
D APH_1110 outer membrane efflux protein K12340 tolC; outer membrane protein
C 04010 MAPK signaling pathway
C 04013 MAPK signaling pathway - fly
C 04016 MAPK signaling pathway - plant
C 04011 MAPK signaling pathway - yeast
C 04012 ErbB signaling pathway
C 04014 Ras signaling pathway
C 04015 Rap1 signaling pathway
C 04310 Wnt signaling pathway
C 04330 Notch signaling pathway
C 04340 Hedgehog signaling pathway
C 04341 Hedgehog signaling pathway - fly
C 04350 TGF-beta signaling pathway
C 04390 Hippo signaling pathway
C 04391 Hippo signaling pathway - fly
C 04392 Hippo signaling pathway - multiple species
C 04370 VEGF signaling pathway
C 04371 Apelin signaling pathway
C 04630 JAK-STAT signaling pathway
C 04064 NF-kappa B signaling pathway
C 04668 TNF signaling pathway
C 04066 HIF-1 signaling pathway
C 04068 FoxO signaling pathway
C 04020 Calcium signaling pathway
C 04070 Phosphatidylinositol signaling system
C 04072 Phospholipase D signaling pathway
C 04071 Sphingolipid signaling pathway
C 04024 cAMP signaling pathway
C 04022 cGMP-PKG signaling pathway
C 04151 PI3K-Akt signaling pathway
C 04152 AMPK signaling pathway
C 04150 mTOR signaling pathway
C 04075 Plant hormone signal transduction
B
B 09133 Signaling molecules and interaction
C 04080 Neuroactive ligand-receptor interaction
C 04060 Cytokine-cytokine receptor interaction
C 04061 Viral protein interaction with cytokine and cytokine receptor
C 04512 ECM-receptor interaction
C 04514 Cell adhesion molecules
#
A09140 Cellular Processes
B
B 09141 Transport and catabolism
C 04144 Endocytosis
C 04145 Phagosome
C 04142 Lysosome
C 04146 Peroxisome
C 04140 Autophagy - animal
C 04138 Autophagy - yeast
C 04136 Autophagy - other
C 04137 Mitophagy - animal
C 04139 Mitophagy - yeast
C 04148 Efferocytosis
D APH_0401 petA; ubiquinol-cytochrome c reductase, iron-sulfur subunit K00411 UQCRFS1; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:7.1.1.8]
B
B 09143 Cell growth and death
C 04110 Cell cycle
C 04111 Cell cycle - yeast
C 04112 Cell cycle - Caulobacter
C 04113 Meiosis - yeast
C 04114 Oocyte meiosis
C 04210 Apoptosis
C 04214 Apoptosis - fly
C 04215 Apoptosis - multiple species
C 04216 Ferroptosis
C 04217 Necroptosis
C 04115 p53 signaling pathway
C 04218 Cellular senescence
B
B 09144 Cellular community - eukaryotes
C 04510 Focal adhesion
C 04520 Adherens junction
C 04530 Tight junction
C 04540 Gap junction
C 04550 Signaling pathways regulating pluripotency of stem cells
B
B 09145 Cellular community - prokaryotes
C 02024 Quorum sensing [PATH:aph02024]
D APH_1314 ribA; GTP cyclohydrolase II K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D APH_1319 GTP cyclohydrolase II, degenerate K01497 ribA; GTP cyclohydrolase II [EC:3.5.4.25]
D APH_0037 ribD; riboflavin biosynthesis protein RibD K11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]
D APH_0540 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_0541 putative membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_1030 secE; preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D APH_0039 secG; preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG
D APH_0299 secY; preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D APH_1090 yajC; preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D APH_1178 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D APH_1227 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D APH_0097 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D APH_0349 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
C 05111 Biofilm formation - Vibrio cholerae
C 02025 Biofilm formation - Pseudomonas aeruginosa
C 02026 Biofilm formation - Escherichia coli
B
B 09142 Cell motility
C 02030 Bacterial chemotaxis
C 02040 Flagellar assembly
D APH_0576 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
C 04814 Motor proteins
C 04820 Cytoskeleton in muscle cells
D APH_0695 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
C 04810 Regulation of actin cytoskeleton
#
A09150 Organismal Systems
B
B 09151 Immune system
C 04640 Hematopoietic cell lineage
C 04610 Complement and coagulation cascades
C 04611 Platelet activation
C 04613 Neutrophil extracellular trap formation
C 04620 Toll-like receptor signaling pathway
C 04624 Toll and Imd signaling pathway
C 04621 NOD-like receptor signaling pathway
C 04622 RIG-I-like receptor signaling pathway
C 04623 Cytosolic DNA-sensing pathway
C 04625 C-type lectin receptor signaling pathway
C 04650 Natural killer cell mediated cytotoxicity
C 04612 Antigen processing and presentation
C 04660 T cell receptor signaling pathway
C 04658 Th1 and Th2 cell differentiation
C 04659 Th17 cell differentiation
C 04657 IL-17 signaling pathway
C 04662 B cell receptor signaling pathway
C 04664 Fc epsilon RI signaling pathway
C 04666 Fc gamma R-mediated phagocytosis
C 04670 Leukocyte transendothelial migration
C 04672 Intestinal immune network for IgA production
C 04062 Chemokine signaling pathway
B
B 09152 Endocrine system
C 04911 Insulin secretion
C 04910 Insulin signaling pathway
C 04922 Glucagon signaling pathway
C 04923 Regulation of lipolysis in adipocytes
C 04920 Adipocytokine signaling pathway
C 03320 PPAR signaling pathway
C 04929 GnRH secretion
C 04912 GnRH signaling pathway
C 04913 Ovarian steroidogenesis
C 04915 Estrogen signaling pathway
C 04914 Progesterone-mediated oocyte maturation
C 04917 Prolactin signaling pathway
C 04921 Oxytocin signaling pathway
C 04926 Relaxin signaling pathway
C 04935 Growth hormone synthesis, secretion and action
C 04918 Thyroid hormone synthesis
C 04919 Thyroid hormone signaling pathway
C 04928 Parathyroid hormone synthesis, secretion and action
C 04916 Melanogenesis
C 04924 Renin secretion
C 04614 Renin-angiotensin system
C 04925 Aldosterone synthesis and secretion
C 04927 Cortisol synthesis and secretion
B
B 09153 Circulatory system
C 04260 Cardiac muscle contraction
C 04261 Adrenergic signaling in cardiomyocytes
C 04270 Vascular smooth muscle contraction
B
B 09154 Digestive system
C 04970 Salivary secretion
C 04971 Gastric acid secretion
C 04972 Pancreatic secretion
C 04976 Bile secretion
C 04973 Carbohydrate digestion and absorption
C 04974 Protein digestion and absorption
C 04975 Fat digestion and absorption
C 04979 Cholesterol metabolism
C 04977 Vitamin digestion and absorption
C 04980 Cobalamin transport and metabolism
C 04978 Mineral absorption
B
B 09155 Excretory system
C 04962 Vasopressin-regulated water reabsorption
C 04960 Aldosterone-regulated sodium reabsorption
C 04961 Endocrine and other factor-regulated calcium reabsorption
C 04964 Proximal tubule bicarbonate reclamation
C 04966 Collecting duct acid secretion
B
B 09156 Nervous system
C 04724 Glutamatergic synapse
C 04727 GABAergic synapse
C 04725 Cholinergic synapse
C 04728 Dopaminergic synapse
C 04726 Serotonergic synapse
C 04720 Long-term potentiation
C 04730 Long-term depression
C 04723 Retrograde endocannabinoid signaling
C 04721 Synaptic vesicle cycle
C 04722 Neurotrophin signaling pathway
B
B 09157 Sensory system
C 04744 Phototransduction
C 04745 Phototransduction - fly
C 04740 Olfactory transduction
C 04742 Taste transduction
C 04750 Inflammatory mediator regulation of TRP channels
B
B 09158 Development and regeneration
C 04320 Dorso-ventral axis formation
C 04360 Axon guidance
C 04361 Axon regeneration
C 04380 Osteoclast differentiation
B
B 09149 Aging
C 04211 Longevity regulating pathway
C 04212 Longevity regulating pathway - worm
C 04213 Longevity regulating pathway - multiple species
B
B 09159 Environmental adaptation
C 04710 Circadian rhythm
C 04713 Circadian entrainment
C 04711 Circadian rhythm - fly
C 04712 Circadian rhythm - plant
C 04714 Thermogenesis
C 04626 Plant-pathogen interaction
#
A09160 Human Diseases
B
B 09161 Cancer: overview
C 05200 Pathways in cancer
C 05202 Transcriptional misregulation in cancer
C 05206 MicroRNAs in cancer
C 05205 Proteoglycans in cancer
C 05204 Chemical carcinogenesis - DNA adducts
C 05207 Chemical carcinogenesis - receptor activation
C 05208 Chemical carcinogenesis - reactive oxygen species
C 05203 Viral carcinogenesis
C 05230 Central carbon metabolism in cancer
C 05231 Choline metabolism in cancer
C 05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
B
B 09162 Cancer: specific types
C 05210 Colorectal cancer
C 05212 Pancreatic cancer
C 05225 Hepatocellular carcinoma
C 05226 Gastric cancer
C 05214 Glioma
C 05216 Thyroid cancer
C 05221 Acute myeloid leukemia
C 05220 Chronic myeloid leukemia
C 05217 Basal cell carcinoma
C 05218 Melanoma
C 05211 Renal cell carcinoma
C 05219 Bladder cancer
C 05215 Prostate cancer
C 05213 Endometrial cancer
C 05224 Breast cancer
C 05222 Small cell lung cancer
C 05223 Non-small cell lung cancer
B
B 09172 Infectious disease: viral
C 05166 Human T-cell leukemia virus 1 infection
C 05170 Human immunodeficiency virus 1 infection
C 05161 Hepatitis B
C 05160 Hepatitis C
C 05171 Coronavirus disease - COVID-19
C 05164 Influenza A
C 05162 Measles
C 05168 Herpes simplex virus 1 infection
C 05163 Human cytomegalovirus infection
C 05167 Kaposi sarcoma-associated herpesvirus infection
C 05169 Epstein-Barr virus infection
C 05165 Human papillomavirus infection
B
B 09171 Infectious disease: bacterial
C 05110 Vibrio cholerae infection
C 05120 Epithelial cell signaling in Helicobacter pylori infection
C 05130 Pathogenic Escherichia coli infection
C 05132 Salmonella infection
C 05131 Shigellosis
C 05135 Yersinia infection
C 05133 Pertussis
C 05134 Legionellosis
C 05150 Staphylococcus aureus infection
C 05152 Tuberculosis
C 05100 Bacterial invasion of epithelial cells
B
B 09174 Infectious disease: parasitic
C 05146 Amoebiasis
C 05144 Malaria
C 05145 Toxoplasmosis
C 05140 Leishmaniasis
C 05142 Chagas disease
C 05143 African trypanosomiasis
B
B 09163 Immune disease
C 05310 Asthma
C 05322 Systemic lupus erythematosus
C 05323 Rheumatoid arthritis
C 05320 Autoimmune thyroid disease
C 05321 Inflammatory bowel disease
C 05330 Allograft rejection
C 05332 Graft-versus-host disease
C 05340 Primary immunodeficiency
B
B 09164 Neurodegenerative disease
C 05010 Alzheimer disease
C 05012 Parkinson disease
C 05014 Amyotrophic lateral sclerosis
C 05016 Huntington disease
C 05017 Spinocerebellar ataxia
C 05020 Prion disease
C 05022 Pathways of neurodegeneration - multiple diseases
B
B 09165 Substance dependence
C 05030 Cocaine addiction
C 05031 Amphetamine addiction
C 05032 Morphine addiction
C 05033 Nicotine addiction
C 05034 Alcoholism
B
B 09166 Cardiovascular disease
C 05417 Lipid and atherosclerosis
C 05418 Fluid shear stress and atherosclerosis
C 05410 Hypertrophic cardiomyopathy
C 05412 Arrhythmogenic right ventricular cardiomyopathy
C 05414 Dilated cardiomyopathy
C 05415 Diabetic cardiomyopathy
C 05416 Viral myocarditis
B
B 09167 Endocrine and metabolic disease
C 04930 Type II diabetes mellitus
C 04940 Type I diabetes mellitus
C 04950 Maturity onset diabetes of the young
C 04936 Alcoholic liver disease
C 04932 Non-alcoholic fatty liver disease
C 04931 Insulin resistance
C 04933 AGE-RAGE signaling pathway in diabetic complications
C 04934 Cushing syndrome
B
B 09175 Drug resistance: antimicrobial
C 01501 beta-Lactam resistance
D APH_1110 outer membrane efflux protein K12340 tolC; outer membrane protein
C 01502 Vancomycin resistance
C 01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:aph01503]
D APH_1148 protease DO family protein K04771 degP; serine protease Do [EC:3.4.21.107]
D APH_1110 outer membrane efflux protein K12340 tolC; outer membrane protein
B
B 09176 Drug resistance: antineoplastic
C 01521 EGFR tyrosine kinase inhibitor resistance
C 01524 Platinum drug resistance
C 01523 Antifolate resistance
C 01522 Endocrine resistance
#
A09180 Brite Hierarchies
B
B 09181 Protein families: metabolism
C 01000 Enzymes [BR:aph01000]
C 01001 Protein kinases [BR:aph01001]
D APH_0136 ntrY; nitrogen regulation protein/Sensor Histidine Kinase NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D APH_0944 pleC; Sensor histidine kinase PleC K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
C 01009 Protein phosphatases and associated proteins [BR:aph01009]
D APH_0893 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 01002 Peptidases and inhibitors [BR:aph01002]
D APH_1160 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
D APH_1233 guaA; GMP synthase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
D APH_1300 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
D APH_1159 peptidase, M16 family K07263 pqqL; zinc protease [EC:3.4.24.-]
D APH_1158 peptidase, M16 family K07263 pqqL; zinc protease [EC:3.4.24.-]
D APH_0231 pepA; cytosol aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
D APH_1199 map; methionine aminopeptidase, type I K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
D APH_0353 metallopeptidase, M24 family K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
D APH_0339 putative thermostable metallocarboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
D APH_1179 ftsH; ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D APH_1211 putative membrane-associated zinc metalloprotease K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
D APH_1148 protease DO family protein K04771 degP; serine protease Do [EC:3.4.21.107]
D APH_1214 D-alanyl-D-alanine carboxypeptidase family protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
D APH_0970 clpP; ATP-dependent Clp protease, proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
D APH_0968 lon; ATP-dependent protease La K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
D APH_0802 lepB; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
D APH_0272 sppA; signal peptide peptidase SppA, 36K type K04773 sppA; protease IV [EC:3.4.21.-]
D APH_0022 phage prohead protease, HK97 family K06904 GP4; Escherichia/Staphylococcus phage prohead protease
D APH_1073 hslV; ATP-dependent protease HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
D APH_0705 pmbA; pmbA protein K03592 pmbA; PmbA protein
D APH_1310 tldD; TldD protein K03568 tldD; TldD protein
D APH_1147 hflC; HflC protein K04087 hflC; modulator of FtsH protease HflC
D APH_1146 hflK; HflK protein K04088 hflK; modulator of FtsH protease HflK
C 01003 Glycosyltransferases
C 01005 Lipopolysaccharide biosynthesis proteins
C 01011 Peptidoglycan biosynthesis and degradation proteins [BR:aph01011]
D APH_0745 murB; UDP-N-acetylenolpyruvoylglucosamine reductase K00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]
D APH_1377 mviN; integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase
D APH_1214 D-alanyl-D-alanine carboxypeptidase family protein K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C 01004 Lipid biosynthesis proteins [BR:aph01004]
D APH_0092 fabD; malonyl CoA-acyl carrier protein transacylase K00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]
D APH_0317 fabH; 3-oxoacyl-(acyl-carrier-protein) synthase III K00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]
D APH_0930 fabF; 3-oxoacyl-(acyl-carrier-protein) synthase II K09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]
D APH_0668 fabG; 3-oxoacyl-(acyl-carrier-protein) reductase K00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]
D APH_1208 fabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ K02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]
D APH_0473 fabI; enoyl-(acyl-carrier-protein) reductase K00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]
D APH_1048 fabK; enoyl-(acyl-carrier-protein) reductase II K02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]
D APH_0316 plsX; fatty acid/phospholipid synthesis protein PlsX K03621 plsX; phosphate acyltransferase [EC:2.3.1.274]
D APH_0017 conserved hypothetical protein TIGR00023 K08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]
D APH_1373 1-acyl-sn-glycerol-3-phosphate acyltransferase family protein K00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]
C 01008 Polyketide biosynthesis proteins
C 01006 Prenyltransferases [BR:aph01006]
D APH_0329 ispA; geranyltranstransferase K00795 ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]
D APH_1247 ispB; octaprenyl-diphosphate synthase K02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]
D APH_0431 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D APH_0310 ubiA; 4-hydroxybenzoate octaprenyltransferase K03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]
D APH_1086 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
C 01007 Amino acid related enzymes [BR:aph01007]
D APH_0607 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D APH_0072 gltX-1; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_0408 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_1244 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D APH_0035 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D APH_0555 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D APH_0700 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D APH_1079 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D APH_0796 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D APH_1224 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D APH_0534 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D APH_0190 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D APH_0120 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D APH_0165 glyQ-2; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D APH_0013 glyQ-1; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D APH_0014 glyS; glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D APH_0427 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D APH_0647 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D APH_1264 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D APH_1059 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D APH_0059 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D APH_0305 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D APH_0660 aspC; aspartate aminotransferase K00812 aspB; aspartate aminotransferase [EC:2.6.1.1]
D APH_1243 hemA; 5-aminolevulinic acid synthase K00643 E2.3.1.37; 5-aminolevulinate synthase [EC:2.3.1.37]
D APH_0979 8-amino-7-oxononanoate synthase, truncated K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D APH_1016 bioF; 8-amino-7-oxononanoate synthase K00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]
D APH_0945 argD; acetylornithine/succinyldiaminopimelate aminotransferase K00821 argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]
D APH_0482 bioA; adenosylmethionine-8-amino-7-oxononanoate aminotransferase K00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]
C 00199 Cytochrome P450
C 00194 Photosynthesis proteins [BR:aph00194]
D APH_0493 atpC; ATP synthase F1, epsilon subunit K02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon
D APH_0494 atpD; ATP synthase F1, beta subunit K02112 ATPF1B; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]
D APH_0813 ATP synthase F1, gamma subunit, truncated K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D APH_0707 atpG; ATP synthase F1, gamma subunit K02115 ATPF1G; F-type H+-transporting ATPase subunit gamma
D APH_1334 atpA; ATP synthase F1, alpha subunit K02111 ATPF1A; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]
D APH_1335 atpH; ATP synthase F1, delta subunit K02113 ATPF1D; F-type H+-transporting ATPase subunit delta
D APH_1189 putative ATP synthase F0, B subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D APH_1190 putative ATP synthase F0, B' subunit K02109 ATPF0B; F-type H+-transporting ATPase subunit b
D APH_1191 atpE; ATP synthase F0, C chain K02110 ATPF0C; F-type H+-transporting ATPase subunit c
D APH_1192 atpB; ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
B
B 09182 Protein families: genetic information processing
C 03000 Transcription factors [BR:aph03000]
D APH_0876 biotin--acetyl-CoA-carboxylase ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D APH_0856 putative biotin--acetyl-CoA-carboxylase ligase, truncated K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D APH_0669 putA; proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
D APH_1004 BolA protein K05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator
D APH_1398 putative dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D APH_0047 ATP cone domain protein K07738 nrdR; transcriptional repressor NrdR
C 03021 Transcription machinery [BR:aph03021]
D APH_0303 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D APH_1024 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D APH_1023 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D APH_0514 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D APH_0576 rpoD; RNA polymerase sigma factor RpoD K03086 rpoD; RNA polymerase primary sigma factor
D APH_0759 rpoH; RNA polymerase sigma-32 factor K03089 rpoH; RNA polymerase sigma-32 factor
D APH_0445 nusA; N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA
D APH_0538 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB
D APH_1029 nusG; transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG
D APH_1398 putative dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D APH_1333 greA; transcription elongation factor GreA K03624 greA; transcription elongation factor GreA
D APH_0064 rho-1; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D APH_1071 rho-2; transcription termination factor Rho K03628 rho; transcription termination factor Rho
C 03019 Messenger RNA biogenesis [BR:aph03019]
D APH_0345 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12]
D APH_1149 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D APH_1036 metallo-beta-lactamase family, beta-CASP subfamily K12574 rnj; ribonuclease J [EC:3.1.-.-]
D APH_0695 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APH_0767 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
D APH_0064 rho-1; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D APH_1071 rho-2; transcription termination factor Rho K03628 rho; transcription termination factor Rho
D APH_0346 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D APH_0240 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D APH_1216 polyA polymerase/tRNA nucleotidyltransferase family protein K00970 pcnB; poly(A) polymerase [EC:2.7.7.19]
C 03041 Spliceosome
C 03011 Ribosome [BR:aph03011]
D APH_0273 rpsA; ribosomal protein S1 K02945 RP-S1; small subunit ribosomal protein S1
D APH_0397 rpsB; ribosomal protein S2 K02967 RP-S2; small subunit ribosomal protein S2
D APH_0286 rpsC; ribosomal protein S3 K02982 RP-S3; small subunit ribosomal protein S3
D APH_0989 rpsD; ribosomal protein S4 K02986 RP-S4; small subunit ribosomal protein S4
D APH_0297 rpsE; ribosomal protein S5 K02988 RP-S5; small subunit ribosomal protein S5
D APH_0151 rpsF; ribosomal protein S6 K02990 RP-S6; small subunit ribosomal protein S6
D APH_1034 rpsG; ribosomal protein S7 K02992 RP-S7; small subunit ribosomal protein S7
D APH_0294 rpsH; ribosomal protein S8 K02994 RP-S8; small subunit ribosomal protein S8
D APH_1107 rpsI; ribosomal protein S9 K02996 RP-S9; small subunit ribosomal protein S9
D APH_0279 rpsJ; ribosomal protein S10 K02946 RP-S10; small subunit ribosomal protein S10
D APH_0302 rpsK; ribosomal protein S11 K02948 RP-S11; small subunit ribosomal protein S11
D APH_1035 rpsL; ribosomal protein S12 K02950 RP-S12; small subunit ribosomal protein S12
D APH_0301 rpsM; ribosomal protein S13 K02952 RP-S13; small subunit ribosomal protein S13
D APH_0293 rpsN; ribosomal protein S14p/S29e K02954 RP-S14; small subunit ribosomal protein S14
D APH_0768 rpsO; ribosomal protein S15 K02956 RP-S15; small subunit ribosomal protein S15
D APH_0054 rpsP; ribosomal protein S16 K02959 RP-S16; small subunit ribosomal protein S16
D APH_0289 rpsQ; ribosomal protein S17 K02961 RP-S17; small subunit ribosomal protein S17
D APH_0152 rpsR; ribosomal protein S18 K02963 RP-S18; small subunit ribosomal protein S18
D APH_0284 rpsS; ribosomal protein S19 K02965 RP-S19; small subunit ribosomal protein S19
D APH_1374 rpsT; ribosomal protein S20 K02968 RP-S20; small subunit ribosomal protein S20
D APH_1051 rpsU; ribosomal protein S21 K02970 RP-S21; small subunit ribosomal protein S21
D APH_1027 rplA; ribosomal protein L1 K02863 RP-L1; large subunit ribosomal protein L1
D APH_0283 rplB; ribosomal protein L2 K02886 RP-L2; large subunit ribosomal protein L2
D APH_0280 rplC; ribosomal protein L3 K02906 RP-L3; large subunit ribosomal protein L3
D APH_0281 rplD; ribosomal protein L4 K02926 RP-L4; large subunit ribosomal protein L4
D APH_0292 rplE; ribosomal protein L5 K02931 RP-L5; large subunit ribosomal protein L5
D APH_0295 rplF; ribosomal protein L6 K02933 RP-L6; large subunit ribosomal protein L6
D APH_0153 rplI; ribosomal protein L9 K02939 RP-L9; large subunit ribosomal protein L9
D APH_1026 rplJ; ribosomal protein L10 K02864 RP-L10; large subunit ribosomal protein L10
D APH_1028 rplK; ribosomal protein L11 K02867 RP-L11; large subunit ribosomal protein L11
D APH_1025 rplL; ribosomal protein L7/L12 K02935 RP-L7; large subunit ribosomal protein L7/L12
D APH_1108 rplM; ribosomal protein L13 K02871 RP-L13; large subunit ribosomal protein L13
D APH_0290 rplN; ribosomal protein L14 K02874 RP-L14; large subunit ribosomal protein L14
D APH_0298 rplO; ribosomal protein L15 K02876 RP-L15; large subunit ribosomal protein L15
D APH_0287 rplP; ribosomal protein L16 K02878 RP-L16; large subunit ribosomal protein L16
D APH_0304 rplQ; ribosomal protein L17 K02879 RP-L17; large subunit ribosomal protein L17
D APH_0296 rplR; 50S ribosomal protein L18 K02881 RP-L18; large subunit ribosomal protein L18
D APH_1266 rplS; ribosomal protein L19 K02884 RP-L19; large subunit ribosomal protein L19
D APH_0060 rplT; ribosomal protein L20 K02887 RP-L20; large subunit ribosomal protein L20
D APH_0697 rplU; ribosomal protein L21 K02888 RP-L21; large subunit ribosomal protein L21
D APH_0285 rplV; ribosomal protein L22 K02890 RP-L22; large subunit ribosomal protein L22
D APH_0282 rplW; ribosomal protein L23 K02892 RP-L23; large subunit ribosomal protein L23
D APH_0291 rplX; ribosomal protein L24 K02895 RP-L24; large subunit ribosomal protein L24
D APH_0698 rpmA; ribosomal protein L27 K02899 RP-L27; large subunit ribosomal protein L27
D APH_0359 rpmB; ribosomal protein L28 K02902 RP-L28; large subunit ribosomal protein L28
D APH_0288 rpmC; ribosomal protein L29 K02904 RP-L29; large subunit ribosomal protein L29
D APH_0090 putative 50S ribosomal protein L31 K02909 RP-L31; large subunit ribosomal protein L31
D APH_0315 rpmF; ribosomal protein L32 K02911 RP-L32; large subunit ribosomal protein L32
D APH_0925 rpmG; ribosomal protein L33 K02913 RP-L33; large subunit ribosomal protein L33
D APH_0309 rpmH; ribosomal protein L34 K02914 RP-L34; large subunit ribosomal protein L34
D APH_0061 rpmI; ribosomal protein L35 K02916 RP-L35; large subunit ribosomal protein L35
D APH_0508 rpmJ; ribosomal protein L36 K02919 RP-L36; large subunit ribosomal protein L36
D APH_1302 ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 K02897 RP-L25; large subunit ribosomal protein L25
D APH_0085 rrfC; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D APH_1000 rrsA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D APH_0084 rrlB; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
C 03009 Ribosome biogenesis [BR:aph03009]
D APH_1149 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D APH_0350 era; GTP-binding protein Era K03595 era; GTPase
D APH_0694 GTP-binding protein, GTP1/Obg family K03979 obgE; GTPase [EC:3.6.5.-]
D APH_1398 putative dnaK suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D APH_0445 nusA; N utilization substance protein A K02600 nusA; transcription termination/antitermination protein NusA
D APH_0538 nusB; N utilization substance protein B K03625 nusB; transcription antitermination protein NusB
D APH_1029 nusG; transcription termination/antitermination factor NusG K02601 nusG; transcription termination/antitermination protein NusG
D APH_0622 ksgA; dimethyladenosine transferase K02528 ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]
D APH_0075 putative methyltransferase K08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]
D APH_0794 conserved hypothetical protein TIGR00046 K09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]
D APH_0690 mraW; S-adenosyl-methyltransferase MraW K03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]
D APH_0275 RNA methyltransferase, TrmH family, group 3 K03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]
D APH_0504 rrmJ; ribosomal RNA large subunit methyltransferase J K02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]
D APH_0549 rluC; ribosomal large subunit pseudouridine synthase C K06179 rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]
D APH_0362 ribosomal large subunit pseudouridine synthase, RluA family K06180 rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]
D APH_1268 rimM; 16S rRNA processing protein RimM K02860 rimM; 16S rRNA processing protein RimM
D APH_0345 ribonuclease, Rne/Rng family K08300 rne; ribonuclease E [EC:3.1.26.12]
D APH_0332 conserved hypothetical protein TIGR00250 K07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]
D APH_0390 putative GTP-binding protein EngA K03977 engA; GTPase
D APH_0782 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D APH_0447 rbfA; ribosome-binding factor A K02834 rbfA; ribosome-binding factor A
D APH_0207 iojap-related protein K09710 ybeB; ribosome-associated protein
D APH_1290 conserved hypothetical protein TIGR00043 K07042 ybeY; probable rRNA maturation factor
D APH_1285 ychF; GTP-binding protein YchF K06942 ychF; ribosome-binding ATPase
C 03016 Transfer RNA biogenesis [BR:aph03016]
D APH_0072 gltX-1; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_0408 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_0647 proS; prolyl-tRNA synthetase K01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]
D APH_0796 ileS; isoleucyl-tRNA synthetase K01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]
D APH_0534 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D APH_1079 metG; methionyl-tRNA synthetase K01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]
D APH_0700 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D APH_0190 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D APH_1059 alaS; alanyl-tRNA synthetase K01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]
D APH_1264 thrS; threonyl-tRNA synthetase K01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]
D APH_0427 serS; seryl-tRNA synthetase K01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]
D APH_0555 cysS; cysteinyl-tRNA synthetase K01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]
D APH_1224 valS; valyl-tRNA synthetase K01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]
D APH_0120 hisS; histidyl-tRNA synthetase K01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]
D APH_0059 pheS; phenylalanyl-tRNA synthetase, alpha subunit K01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]
D APH_0305 pheT; phenylalanyl-tRNA synthetase, beta subunit K01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]
D APH_1244 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D APH_0035 trpS; tryptophanyl-tRNA synthetase K01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]
D APH_0860 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D APH_0502 truA; tRNA pseudouridine synthase A K06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]
D APH_0769 truB; tRNA pseudouridine synthase B K03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]
D APH_0674 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0673 rrf2 family protein/cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0782 Sua5/YciO/YrdC/YwlC family protein K07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]
D APH_0431 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase K00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]
D APH_1288 trmE; tRNA modification GTPase TrmE K03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]
D APH_0224 pyridine nucleotide-disulfide oxidoreductase K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D APH_0308 rnpA; ribonuclease P protein component K03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]
D APH_0216 sRNA K01978 rnpB; M1 RNA
D APH_1098 3''-5'' exonuclease family protein K03684 rnd; ribonuclease D [EC:3.1.13.5]
D APH_0137 putative ribonuclease D K03684 rnd; ribonuclease D [EC:3.1.13.5]
D APH_0607 lysS; lysyl-tRNA synthetase K04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]
D APH_0165 glyQ-2; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D APH_0013 glyQ-1; glycyl-tRNA synthetase, alpha subunit K01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]
D APH_0014 glyS; glycyl-tRNA synthetase, beta subunit K01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]
D APH_0321 cytidine and deoxycytidylate deaminase family protein K11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]
D APH_0575 putative tRNA-dihydrouridine synthase K05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]
D APH_0880 miaB; tRNA-i(6)A37 thiotransferase enzyme MiaB K06168 miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]
D APH_1267 trmD; tRNA (guanine-N1)-methyltransferase K00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]
D APH_0910 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]
D APH_0676 iron-sulfur cluster assembly accessory protein K13628 iscA; iron-sulfur cluster assembly protein
D APH_1270 aminomethyl transferase family protein K06980 ygfZ; tRNA-modifying protein YgfZ
D APH_0314 tgt; queuine tRNA-ribosyltransferase K00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]
D APH_1180 tilS; tRNA(Ile)-lysidine synthetase K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D APH_1056 putative cell cycle protein MesJ K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D APH_1093 putative cell cycle protein MesJ K04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]
D APH_0610 glycoprotease family protein K14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB
D APH_0626 putative metalloendopeptidase, glycoprotease family K25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]
D APH_1344 conserved hypothetical protein TIGR00150 K06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE
D APH_0767 pnp; polyribonucleotide nucleotidyltransferase K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
C 03012 Translation factors [BR:aph03012]
D APH_0446 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D APH_1263 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D APH_0398 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts
D APH_1032 tuf-2; translation elongation factor Tu K02358 tuf; elongation factor Tu
D APH_0278 tuf-1; translation elongation factor Tu K02358 tuf; elongation factor Tu
D APH_1033 fusA; translation elongation factor G K02355 fusA; elongation factor G
D APH_0420 prfA; peptide chain release factor 1 K02835 prfA; peptide chain release factor 1
D APH_0112 frr; ribosome recycling factor K02838 frr; ribosome recycling factor
D APH_1200 modification methylase, HemK family K02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]
D APH_1301 pth; peptidyl-tRNA hydrolase K01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]
D APH_0395 infA; translation initiation factor IF-1 K02518 infA; translation initiation factor IF-1
D APH_0547 efp; translation elongation factor P K02356 efp; elongation factor P
D APH_0468 peptide chain release factor 2, truncated K02836 prfB; peptide chain release factor 2
D APH_0479 prfB; peptide chain release factor 2 K02836 prfB; peptide chain release factor 2
C 03110 Chaperones and folding catalysts [BR:aph03110]
D APH_0450 clpA; ATP-dependent Clp protease, ATP-binding subunit ClpA K03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA
D APH_0235 clpB; ATP-dependent chaperone protein ClpB K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
D APH_0969 clpX; ATP-dependent Clp protease, ATP-binding subunit ClpX K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
D APH_1074 hslU; ATP-dependent Hsl protease, ATP-binding subunit HslU K03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU
D APH_0893 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
D APH_0346 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D APH_0678 hscA; chaperone protein HscA K04044 hscA; molecular chaperone HscA
D APH_0240 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D APH_0015 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D APH_0677 hscB; co-chaperone protein hscB K04082 hscB; molecular chaperone HscB
D APH_0036 grpE; co-chaperone GrpE K03687 GRPE; molecular chaperone GrpE
D APH_0241 groS; 10 kDa chaperonin K04078 groES; chaperonin GroES
D APH_1148 protease DO family protein K04771 degP; serine protease Do [EC:3.4.21.107]
D APH_1179 ftsH; ATP-dependent metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
D APH_1192 atpB; ATP synthase F0, A subunit K02108 ATPF0A; F-type H+-transporting ATPase subunit a
D APH_0097 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D APH_0608 ppiC/parvulin rotamase family protein K03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]
D APH_0080 trx; thioredoxin K03671 TXN; thioredoxin
D APH_1162 grxC; glutaredoxin 3 K03676 grxC; glutaredoxin 3
D APH_0139 glutaredoxin-related protein K07390 grxD; monothiol glutaredoxin
D APH_0141 putative thiol:disulfide oxidoreductase K02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE
C 04131 Membrane trafficking [BR:aph04131]
D APH_1217 ndk; nucleoside diphosphate kinase K00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]
D APH_1349 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D APH_0893 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 04121 Ubiquitin system [BR:aph04121]
C 03051 Proteasome [BR:aph03051]
D APH_0893 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
C 03032 DNA replication proteins [BR:aph03032]
D APH_0109 rnhA; ribonuclease H1 K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D APH_0784 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D APH_1281 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D APH_0271 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D APH_0474 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D APH_0323 dnaB; replicative DNA helicase K02314 dnaB; replicative DNA helicase [EC:5.6.2.3]
D APH_0571 dnaG; DNA primase K02316 dnaG; DNA primase [EC:2.7.7.101]
D APH_0465 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D APH_1003 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D APH_1097 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D APH_1252 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D APH_0783 conserved domain protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D APH_0730 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D APH_1348 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D APH_1022 rnhB; ribonuclease HII K03470 rnhB; ribonuclease HII [EC:3.1.26.4]
D APH_0138 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D APH_0899 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D APH_0716 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D APH_0597 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
C 03036 Chromosome and associated proteins [BR:aph03036]
D APH_1149 rnc; ribonuclease III K03685 rnc; ribonuclease III [EC:3.1.26.3]
D APH_0784 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D APH_1281 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D APH_0271 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D APH_0474 dnaA; chromosomal replication initiator protein DnaA K02313 dnaA; chromosomal replication initiator protein
D APH_1164 ftsA-1; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D APH_1183 ftsA-2; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D APH_0955 FtsK/SpoIIIE family protein K03466 ftsK; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family
D APH_0195 cell division protein FtsQ K03589 ftsQ; cell division protein FtsQ
D APH_0129 tubulin/FtsZ family, C-terminal domain protein K03531 ftsZ; cell division protein FtsZ
D APH_1292 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D APH_0266 conserved hypothetical protein K09888 zapA; cell division protein ZapA
D APH_0262 ATPase, AFG1 family K06916 zapE; cell division protein ZapE
D APH_0770 mreB; rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D APH_0614 putative rod shape-determining protein K03570 mreC; rod shape-determining protein MreC
D APH_0224 pyridine nucleotide-disulfide oxidoreductase K03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme
D APH_0200 xerC; tyrosine recombinase XerC K03733 xerC; integrase/recombinase XerC
D APH_0040 xerD; tyrosine recombinase XerD K04763 xerD; integrase/recombinase XerD
D APH_1111 ATP-binding protein, Mrp/Nbp35 family K03593 mrp; ATP-binding protein involved in chromosome partitioning
D APH_0421 putative GTP-binding protein EngB K03978 engB; GTP-binding protein
C 03400 DNA repair and recombination proteins [BR:aph03400]
D APH_0897 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D APH_0379 dut; deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D APH_1371 uracil-DNA glycosylase, family 4 K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
D APH_0411 mutM; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
D APH_0471 exodeoxyribonuclease III, N-terminal truncated K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D APH_0505 xth; exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D APH_1165 recJ; single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D APH_0138 ligA; DNA ligase, NAD-dependent K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D APH_0537 uvrA; excinuclease ABC, A subunit K03701 uvrA; excinuclease ABC subunit A
D APH_1367 uvrB; excinuclease ABC, B subunit K03702 uvrB; excinuclease ABC subunit B
D APH_0884 uvrC; excinuclease ABC, C subunit K03703 uvrC; excinuclease ABC subunit C
D APH_0903 helicase, UvrD/Rep family K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
D APH_1024 rpoB; DNA-directed RNA polymerase, beta subunit K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
D APH_1023 rpoC; DNA-directed RNA polymerase, beta' subunit K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
D APH_0303 rpoA; DNA-directed RNA polymerase, alpha subunit K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
D APH_0514 rpoZ; DNA-directed RNA polymerase, omega subunit K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
D APH_0107 mfd; transcription-repair coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
D APH_0857 mutS; DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D APH_0939 mutL; DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D APH_1322 xseA; exodeoxyribonuclease VII, large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
D APH_0079 xseB; exodeoxyribonuclease VII, small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D APH_1003 dnaE; DNA polymerase III, alpha subunit K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
D APH_1097 dnaN; DNA polymerase III, beta subunit K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
D APH_1252 holA; DNA polymerase III, delta subunit K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
D APH_0783 conserved domain protein K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
D APH_0730 dnaQ; DNA polymerase III, epsilon subunit K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D APH_1348 dnaX; DNA polymerase III, subunits gamma and tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D APH_0465 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D APH_1354 recA; recA protein K03553 recA; recombination protein RecA
D APH_0167 ruvA; Holliday junction DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
D APH_0166 ruvB; holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
D APH_0018 ruvC; crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D APH_0356 priA; primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
D APH_1409 putative DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
D APH_1298 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
D APH_0736 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
D APH_0988 recR; recombination protein RecR K06187 recR; recombination protein RecR
D APH_0258 ATP-dependent DNA helicase, UvrD/Rep family K16898 addA; ATP-dependent helicase/nuclease subunit A [EC:5.6.2.4 3.1.-.-]
D APH_0849 conserved hypothetical protein K16899 addB; ATP-dependent helicase/nuclease subunit B [EC:5.6.2.4 3.1.-.-]
D APH_0899 gyrA; DNA gyrase, A subunit K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
D APH_0716 gyrB; DNA gyrase, B subunit K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
D APH_0597 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
D APH_0784 hup; DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
D APH_1281 ihfA; integration host factor, alpha subunit K04764 ihfA; integration host factor subunit alpha
D APH_0271 ihfB; integration host factor, beta subunit K05788 ihfB; integration host factor subunit beta
D APH_0331 nrdA; ribonucleoside-diphosphate reductase, alpha subunit K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D APH_0560 nrdB; ribonucleoside-diphosphate reductase, beta subunit K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C 03029 Mitochondrial biogenesis [BR:aph03029]
D APH_0402 petB; ubiquinol-cytochrome c reductase, cytochrome b K00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit
D APH_0446 infB; translation initiation factor IF-2 K02519 infB; translation initiation factor IF-2
D APH_1263 infC; translation initiation factor IF-3 K02520 infC; translation initiation factor IF-3
D APH_0398 tsf; translation elongation factor Ts K02357 tsf; elongation factor Ts
D APH_1032 tuf-2; translation elongation factor Tu K02358 tuf; elongation factor Tu
D APH_0278 tuf-1; translation elongation factor Tu K02358 tuf; elongation factor Tu
D APH_1033 fusA; translation elongation factor G K02355 fusA; elongation factor G
D APH_0350 era; GTP-binding protein Era K03595 era; GTPase
D APH_1244 tyrS; tyrosyl-tRNA synthetase K01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]
D APH_0534 leuS; leucyl-tRNA synthetase K01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]
D APH_0190 aspS; aspartyl-tRNA synthetase K01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]
D APH_0700 argS; arginyl-tRNA synthetase K01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]
D APH_0748 gatA; glutamyl-tRNA(Gln) amidotransferase, A subunit K02433 gatA; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]
D APH_0470 gatB; glutamyl-tRNA(Gln) amidotransferase, B subunit K02434 gatB; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]
D APH_1113 gatC; glutamyl-tRNA(Gln) amidotransferase, C subunit K02435 gatC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]
D APH_0465 ssb; single-strand binding protein K03111 ssb; single-strand DNA-binding protein
D APH_1210 outer membrane protein, OMP85 family K07277 SAM50; outer membrane protein insertion porin family
D APH_0346 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D APH_0036 grpE; co-chaperone GrpE K03687 GRPE; molecular chaperone GrpE
D APH_0240 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D APH_0241 groS; 10 kDa chaperonin K04078 groES; chaperonin GroES
D APH_0015 dnaJ; chaperone protein DnaJ K03686 dnaJ; molecular chaperone DnaJ
D APH_0674 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0673 rrf2 family protein/cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0675 iscU; FeS cluster assembly scaffold IscU K22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial
D APH_0679 iron-sulfur cluster-binding protein K22071 FDX2; ferredoxin-2, mitochondrial
D APH_0677 hscB; co-chaperone protein hscB K04082 hscB; molecular chaperone HscB
D APH_0139 glutaredoxin-related protein K07390 grxD; monothiol glutaredoxin
D APH_0766 conserved hypothetical protein K18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]
D APH_0566 conserved hypothetical protein K18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7
D APH_1111 ATP-binding protein, Mrp/Nbp35 family K03593 mrp; ATP-binding protein involved in chromosome partitioning
D APH_1086 cyoE; protoheme IX farnesyltransferase K02257 COX10; heme o synthase [EC:2.5.1.141]
D APH_1150 ctaG; cytochrome c oxidase assembly protein CtaG K02258 COX11; cytochrome c oxidase assembly protein subunit 11
D APH_0123 putative cytochrome oxidase assembly protein K02259 COX15; heme a synthase [EC:1.17.99.9]
D APH_0540 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_0541 putative membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_1171 conserved hypothetical protein K14998 SURF1; surfeit locus 1 family protein
D APH_1049 msp5; major surface protein 5 K07152 SCO1; protein SCO1
D APH_0893 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
B
B 09183 Protein families: signaling and cellular processes
C 02000 Transporters [BR:aph02000]
D APH_0157 putative ABC transporter, ATP-binding protein/permease protein K06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial
D APH_0256 type I secretion system ATPase/hypothetical protein K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
D APH_0051 iron-binding protein K02012 afuA; iron(III) transport system substrate-binding protein
D APH_1045 ABC transporter, permease protein K02011 afuB; iron(III) transport system permease protein
D APH_0986 ABC transporter, ATP-binding protein K02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]
D APH_0045 mce-related protein K02067 mlaD; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein
D APH_0003 putative ABC transporter, permease protein K02066 mlaE; phospholipid/cholesterol/gamma-HCH transport system permease protein
D APH_0004 ABC transporter, ATP-binding protein K02065 mlaF; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein
D APH_1394 conserved hypothetical protein K07323 mlaC; phospholipid transport system substrate-binding protein
D APH_1050 putative phosphate ABC transporter, periplasmic phosphate-binding protein K02040 pstS; phosphate transport system substrate-binding protein
D APH_1060 pstC; phosphate ABC transporter, permease protein PstC K02037 pstC; phosphate transport system permease protein
D APH_0370 pstA; phosphate ABC transporter, permease protein PtsA K02038 pstA; phosphate transport system permease protein
D APH_0313 pstB; phosphate ABC transporter, ATP-binding protein K02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]
D APH_0982 putative cation ABC transporter, periplasmic cation-binding protein K09815 znuA; zinc transport system substrate-binding protein
D APH_0399 ABC 3 transport family protein K09816 znuB; zinc transport system permease protein
D APH_0983 putative cation ABC transporter, ATP-binding protein K09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]
D APH_1341 lipoprotein releasing system, transmembrane protein, LolC/E family K09808 lolC_E; lipoprotein-releasing system permease protein
D APH_0041 ABC transporter, ATP-binding protein K09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]
D APH_0168 ccmC; heme exporter protein CcmC K02195 ccmC; heme exporter protein C
D APH_1397 putative heme exporter protein CcmB K02194 ccmB; heme exporter protein B
D APH_0125 ccmA; heme exporter protein CcmA K02193 ccmA; heme exporter protein A [EC:7.6.2.5]
D APH_0053 major facilitator family transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D APH_0848 major facilitator family transporter K03762 proP; MFS transporter, MHS family, proline/betaine transporter
D APH_0164 bicyclomycin resistance protein K07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein
D APH_0496 mgtE; magnesium transporter K06213 mgtE; magnesium transporter
D APH_0940 tolQ; TolQ protein K03562 tolQ; biopolymer transport protein TolQ
D APH_0957 CBS/transporter associated domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
D APH_1110 outer membrane efflux protein K12340 tolC; outer membrane protein
D APH_1210 outer membrane protein, OMP85 family K07277 SAM50; outer membrane protein insertion porin family
D APH_0392 PQQ enzyme repeat domain protein K17713 bamB; outer membrane protein assembly factor BamB
D APH_1087 putative competence lipoprotein ComL K05807 bamD; outer membrane protein assembly factor BamD
D APH_1395 cation efflux family protein K16264 czcD; cobalt-zinc-cadmium efflux system protein
D APH_0444 transporter, AcrB/AcrD/AcrF family K18989 vexF; multidrug efflux pump
D APH_1305 glutathione-regulated potassium-efflux system protein K03455 KEA1_2_3; K+:H+ antiporter
D APH_1182 potassium uptake protein, TrkH family K03498 trkH; trk/ktr system potassium uptake protein
D APH_0344 putative monovalent cation/proton antiporter K05567 mnhC; multicomponent Na+:H+ antiporter subunit C
D APH_0348 NADH-ubiquinone/plastoquinone oxidoreductase family protein K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D APH_0181 NADH-ubiquinone/plastoquinone oxidoreductase family protein K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D APH_0044 NADH-ubiquinone/plastoquinone oxidoreductase family protein K05568 mnhD; multicomponent Na+:H+ antiporter subunit D
D APH_1015 Na+/H+ ion antiporter family protein K05569 mnhE; multicomponent Na+:H+ antiporter subunit E
D APH_0341 putative monovalent cation/proton antiporter, MrpF/PhaF subunit K05570 mnhF; multicomponent Na+:H+ antiporter subunit F
D APH_0342 monovalent cation/proton antiporter, MnhG/PhaG subunit K05571 mnhG; multicomponent Na+:H+ antiporter subunit G
D APH_1377 mviN; integral membrane protein MviN K03980 murJ; putative peptidoglycan lipid II flippase
D APH_0077 auxin efflux carrier family protein K24180 mleP; malate permease and related proteins
D APH_0338 OmpA family protein K03640 pal; peptidoglycan-associated lipoprotein
D APH_1037 TolB family protein K03641 tolB; TolB protein
D APH_1043 type I secretion membrane fusion protein, HlyD family K12537 hasE; membrane fusion protein, type I secretion system
D APH_0394 efflux transporter, RND family, MFP subunit K18990 vexE; membrane fusion protein, multidrug efflux system
D APH_1271 cytochrome c-type biogenesis protein, CcmF/CycK/CcsA family K02198 ccmF; cytochrome c-type biogenesis protein CcmF
C 02044 Secretion system [BR:aph02044]
D APH_1110 outer membrane efflux protein K12340 tolC; outer membrane protein
D APH_0256 type I secretion system ATPase/hypothetical protein K12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease/ATPase
D APH_1043 type I secretion membrane fusion protein, HlyD family K12537 hasE; membrane fusion protein, type I secretion system
D APH_0909 putative twitching motility protein K02669 pilT; twitching motility protein PilT
D APH_0956 YGGT family protein K02221 yggT; YggT family protein
D APH_0306 ComEC/Rec2-related protein K02238 comEC; competence protein ComEC
D APH_0372 virB3; type IV secretion system protein VirB3 K03198 virB3; type IV secretion system protein VirB3
D APH_1129 virB4-2; type IV secretion system protein VirB4-2 K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D APH_0373 virB4-1; type IV secretion system protein VirB4 (VirB4-1) K03199 virB4; type IV secretion system protein VirB4 [EC:7.4.2.8]
D APH_0375 virB6-2; type IV secretion system protein VirB6 family (VirB6-2) K03201 virB6; type IV secretion system protein VirB6
D APH_0376 virB6-3; type IV secretion system protein VirB6 family (VirB6-3) K03201 virB6; type IV secretion system protein VirB6
D APH_0374 virB6-1; type IV secretion system protein VirB6-1 K03201 virB6; type IV secretion system protein VirB6
D APH_0430 virB8-2; type IV secretion system protein VirB8-2 K03203 virB8; type IV secretion system protein VirB8
D APH_1406 virB8-1; type IV secretion protein VirB8-1 K03203 virB8; type IV secretion system protein VirB8
D APH_0081 virB9-2; type IV secretion system protein VirB9-2 K03204 virB9; type IV secretion system protein VirB9
D APH_1405 virB9-1; type IV secretion system protein VirB9 (VirB9-1) K03204 virB9; type IV secretion system protein VirB9
D APH_1404 virB10; type IV secretion system protein VirB10 K03195 virB10; type IV secretion system protein VirB10
D APH_1403 virB11; type IV secretion system protein VirB11 K03196 virB11; type IV secretion system protein VirB11 [EC:7.4.2.8]
D APH_1402 virD4; type IV secretion system protein VirD4 K03205 virD4; type IV secretion system protein VirD4 [EC:7.4.2.8]
D APH_1178 secA; preprotein translocase, SecA subunit K03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]
D APH_0097 secB; protein-export protein SecB K03071 secB; preprotein translocase subunit SecB
D APH_1366 secD; protein-export membrane protein SecD K03072 secD; preprotein translocase subunit SecD
D APH_1030 secE; preprotein translocase, SecE subunit K03073 secE; preprotein translocase subunit SecE
D APH_1326 secF; protein-export membrane protein SecF K03074 secF; preprotein translocase subunit SecF
D APH_0039 secG; preprotein translocase, SecG subunit K03075 secG; preprotein translocase subunit SecG
D APH_0299 secY; preprotein translocase, SecY subunit K03076 secY; preprotein translocase subunit SecY
D APH_0349 ffh; signal recognition particle protein K03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]
D APH_1227 ftsY; signal recognition particle-docking protein FtsY K03110 ftsY; fused signal recognition particle receptor
D APH_1090 yajC; preprotein translocase, YajC subunit K03210 yajC; preprotein translocase subunit YajC
D APH_0540 inner membrane protein, 60 kDa K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_0541 putative membrane protein K03217 yidC; YidC/Oxa1 family membrane protein insertase
D APH_0987 tatA; twin-arginine translocation protein, TatA/E family K03116 tatA; sec-independent protein translocase protein TatA
D APH_0552 putative twin-arginine translocation protein TatB K03117 tatB; sec-independent protein translocase protein TatB
D APH_0443 tatC; Sec-independent protein translocase TatC K03118 tatC; sec-independent protein translocase protein TatC
C 02042 Bacterial toxins [BR:aph02042]
D APH_0957 CBS/transporter associated domain protein K03699 tlyC; magnesium and cobalt exporter, CNNM family
C 02022 Two-component system [BR:aph02022]
D APH_0136 ntrY; nitrogen regulation protein/Sensor Histidine Kinase NtrY K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
D APH_0196 ntrX; Response Regulator NtrX, putative nitrogen assimilation regulatory protein K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
D APH_0944 pleC; Sensor histidine kinase PleC K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
D APH_0551 pleD; Response regulator/GGDEF domain protein PleD K02488 pleD; two-component system, cell cycle response regulator [EC:2.7.7.65]
D APH_1099 ctrA; DNA-binding response regulator CtrA K13584 ctrA; two-component system, cell cycle response regulator CtrA
C 02035 Bacterial motility proteins [BR:aph02035]
D APH_0909 putative twitching motility protein K02669 pilT; twitching motility protein PilT
C 03037 Cilium and associated proteins
C 04812 Cytoskeleton proteins [BR:aph04812]
D APH_0770 mreB; rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D APH_0129 tubulin/FtsZ family, C-terminal domain protein K03531 ftsZ; cell division protein FtsZ
D APH_1292 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D APH_1164 ftsA-1; cell division protein FtsA K03590 ftsA; cell division protein FtsA
D APH_1183 ftsA-2; cell division protein FtsA K03590 ftsA; cell division protein FtsA
C 04147 Exosome [BR:aph04147]
D APH_0893 htpG; chaperone protein HtpG K04079 HSP90A; molecular chaperone HtpG
D APH_0695 eno; enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
D APH_1349 gap; glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]
D APH_1321 pgk; phosphoglycerate kinase K00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]
D APH_0659 antioxidant, AhpC/Tsa family K03386 PRDX2_4; peroxiredoxin 2/4 [EC:1.11.1.24]
D APH_0240 groL; 60 kDa chaperonin K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D APH_0346 dnaK; chaperone protein DnaK K04043 dnaK; molecular chaperone DnaK
D APH_0088 guaB; inosine-5'-monophosphate dehydrogenase K00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]
D APH_1032 tuf-2; translation elongation factor Tu K02358 tuf; elongation factor Tu
D APH_0278 tuf-1; translation elongation factor Tu K02358 tuf; elongation factor Tu
D APH_0860 HIT family protein K02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]
D APH_0300 adk; adenylate kinase K00939 adk; adenylate kinase [EC:2.7.4.3]
D APH_1061 glutamine synthetase domain protein K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_1246 glnA; glutamine synthetase, type I K01915 glnA; glutamine synthetase [EC:6.3.1.2]
D APH_0851 hemB; delta-aminolevulinic acid dehydratase K01698 hemB; porphobilinogen synthase [EC:4.2.1.24]
D APH_1207 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
D APH_0393 lpdA-2; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_1070 lpdA-3; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0065 lpdA-1; dihydrolipoamide dehydrogenase K00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]
D APH_0624 tpiA; triosephosphate isomerase K01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]
C 02048 Prokaryotic defense system [BR:aph02048]
D APH_0129 tubulin/FtsZ family, C-terminal domain protein K03531 ftsZ; cell division protein FtsZ
D APH_1292 ftsZ; cell division protein FtsZ K03531 ftsZ; cell division protein FtsZ
D APH_0770 mreB; rod shape-determining protein MreB K03569 mreB; rod shape-determining protein MreB and related proteins
D APH_0072 gltX-1; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_0408 gltX-2; glutamyl-tRNA synthetase K01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]
D APH_1212 TPR repeat protein K09159 cptB; antitoxin CptB
D APH_0674 iscS; cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
D APH_0673 rrf2 family protein/cysteine desulfurase K04487 iscS; cysteine desulfurase [EC:2.8.1.7]
C 04030 G protein-coupled receptors
C 04050 Cytokine receptors
C 04054 Pattern recognition receptors
C 03310 Nuclear receptors
C 04040 Ion channels
C 04031 GTP-binding proteins
C 04052 Cytokines and neuropeptides
C 04515 Cell adhesion molecules
C 04090 CD molecules
C 01504 Antimicrobial resistance genes [BR:aph01504]
D APH_1110 outer membrane efflux protein K12340 tolC; outer membrane protein
C 00535 Proteoglycans
C 00536 Glycosaminoglycan binding proteins
C 00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
C 04091 Lectins
C 04990 Domain-containing proteins not elsewhere classified
B
B 09185 Viral protein families
C 03200 Viral proteins
C 03210 Viral fusion proteins
B
B 09184 RNA family
C 03100 Non-coding RNAs [BR:aph03100]
D APH_0048 tRNA-Ala K14218 tRNA-Ala; tRNA Ala
D APH_0613 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APH_0008 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APH_1020 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APH_0368 tRNA-Arg K14219 tRNA-Arg; tRNA Arg
D APH_0777 tRNA-Asn K14220 tRNA-Asn; tRNA Asn
D APH_0472 tRNA-Asp K14221 tRNA-Asp; tRNA Asp
D APH_1259 tRNA-Cys K14222 tRNA-Cys; tRNA Cys
D APH_0012 tRNA-Gln K14223 tRNA-Gln; tRNA Gln
D APH_0330 tRNA-Glu K14224 tRNA-Glu; tRNA Glu
D APH_0865 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APH_0277 tRNA-Gly K14225 tRNA-Gly; tRNA Gly
D APH_0073 tRNA-His K14226 tRNA-His; tRNA His
D APH_0699 tRNA-Ile K14227 tRNA-Ile; tRNA Ile
D APH_0990 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_0495 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_0972 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_1315 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_1309 tRNA-Leu K14228 tRNA-Leu; tRNA Leu
D APH_1245 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D APH_0973 tRNA-Lys K14229 tRNA-Lys; tRNA Lys
D APH_0639 tRNA-Met K14230 tRNA-Met; tRNA Met
D APH_0729 tRNA-Met K14230 tRNA-Met; tRNA Met
D APH_0966 tRNA-Met K14230 tRNA-Met; tRNA Met
D APH_0738 tRNA-Met K14230 tRNA-Met; tRNA Met
D APH_0649 tRNA-Phe K14231 tRNA-Phe; tRNA Phe
D APH_0498 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APH_1283 tRNA-Pro K14232 tRNA-Pro; tRNA Pro
D APH_0616 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APH_0034 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APH_1181 tRNA-Ser K14233 tRNA-Ser; tRNA Ser
D APH_0623 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APH_0410 tRNA-Thr K14234 tRNA-Thr; tRNA Thr
D APH_1031 tRNA-Trp K14235 tRNA-Trp; tRNA Trp
D APH_0276 tRNA-Tyr K14236 tRNA-Tyr; tRNA Tyr
D APH_0176 tRNA-Val K14237 tRNA-Val; tRNA Val
D APH_1396 tRNA-Val K14237 tRNA-Val; tRNA Val
D APH_1000 rrsA; 16S ribosomal RNA K01977 16SrRNA; 16S ribosomal RNA
D APH_0084 rrlB; 23S ribosomal RNA K01980 23SrRNA; 23S ribosomal RNA
D APH_0085 rrfC; 5S ribosomal RNA K01985 5SrRNA; 5S ribosomal RNA
D APH_0216 sRNA K01978 rnpB; M1 RNA
D APH_0776 sRNA K15035 ssrA; transfer-messenger RNA
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A09190 Not Included in Pathway or Brite
B
B 09191 Unclassified: metabolism
C 99980 Enzymes with EC numbers
D APH_0257 qor; quinone oxidoreductase K00344 qor; NADPH:quinone reductase [EC:1.6.5.5]
D APH_0795 antioxidant, AhpC/Tsa family K03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]
D APH_1376 lgt; prolipoprotein diacylglyceryl transferase K13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]
D APH_0961 conserved hypothetical protein K09773 ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33]
D APH_0528 hydrolase, TatD family K03424 tatD; TatD DNase family protein [EC:3.1.21.-]
D APH_1012 putative polypeptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D APH_1372 def; peptide deformylase K01462 PDF; peptide deformylase [EC:3.5.1.88]
D APH_1375 peptide deformylase, truncated K01462 PDF; peptide deformylase [EC:3.5.1.88]
D APH_0588 YjeF family protein K23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase / NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]
D APH_1197 hexapeptide transferase family protein K01726 GAMMACA; gamma-carbonic anhydrase [EC:4.2.1.-]
C 99981 Carbohydrate metabolism
C 99982 Energy metabolism
D APH_0027 fdxA; ferredoxin K05524 fdxA; ferredoxin
C 99983 Lipid metabolism
C 99984 Nucleotide metabolism
C 99985 Amino acid metabolism
C 99986 Glycan metabolism
C 99987 Cofactor metabolism
D APH_0984 ubiB; 2-polyprenylphenol 6-hydroxylase K03688 ubiB; ubiquinone biosynthesis protein
D APH_1042 conserved hypothetical protein K18587 COQ9; ubiquinone biosynthesis protein COQ9
D APH_0347 aromatic-rich protein family K18588 COQ10; coenzyme Q-binding protein COQ10
C 99988 Secondary metabolism
C 99999 Others
D APH_1010 phospholipase/carboxylesterase family protein K06999 K06999; phospholipase/carboxylesterase
B
B 09192 Unclassified: genetic information processing
C 99973 Transcription
D APH_0135 cold shock protein, CSD family K03704 cspA; cold shock protein
C 99974 Translation
C 99975 Protein processing
D APH_0971 putative trigger factor K03545 tig; trigger factor
D APH_1331 smpB; SsrA-binding protein K03664 smpB; SsrA-binding protein
D APH_0754 magnesium chelatase, subunit D/I family, ComM subfamily K07391 comM; magnesium chelatase family protein
C 99976 Replication and repair
D APH_0242 radC; DNA repair protein RadC K03630 radC; DNA repair protein RadC
D APH_0428 putative DNA recombination protein RmuC K09760 rmuC; DNA recombination protein RmuC
D APH_0933 putative DNA processing protein DprA K04096 smf; DNA processing protein
D APH_0351 conserved hypothetical protein K07501 K07501; 3'-5' exonuclease
C 99979 Viral proteins
C 99998 Others
D APH_1347 conserved hypothetical protein K09747 ebfC; nucleoid-associated protein EbfC
B
B 09193 Unclassified: signaling and cellular processes
C 99977 Transport
D APH_0307 sodium:alanine symporter family protein K03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family
C 99978 Cell growth
C 99993 Cell motility
C 99995 Signaling proteins
D APH_0451 typA; GTP-binding protein TypA K06207 typA; GTP-binding protein
C 99992 Structural proteins
D APH_0221 putative lipoprotein NlpD K06194 nlpD; lipoprotein NlpD
D APH_0526 ccmE; cytochrome c-type biogenesis protein CcmE K02197 ccmE; cytochrome c-type biogenesis protein CcmE
D APH_0687 cytochrome c biogenesis family protein K02200 ccmH; cytochrome c-type biogenesis protein CcmH
C 99994 Others
D APH_0581 cutA; periplasmic divalent cation tolerance protein CutA K03926 cutA; periplasmic divalent cation tolerance protein
D APH_1120 apaG; apaG protein K06195 apaG; ApaG protein
D APH_0156 frataxin-like domain protein K06202 cyaY; iron-sulfur cluster assembly protein CyaY
B
B 09194 Poorly characterized
C 99996 General function prediction only
D APH_0150 CvpA family protein K03558 cvpA; membrane protein required for colicin V production
D APH_0803 iron-sulfur cluster assembly accessory protein K15724 erpA; iron-sulfur cluster insertion protein
D APH_0481 YihY family protein K07058 K07058; membrane protein
D APH_0962 rhodanese domain protein K07146 K07146; UPF0176 protein
C 99997 Function unknown
D APH_0259 ankyrin repeat protein K06867 K06867; uncharacterized protein
D APH_0178 hydrolase, alpha/beta fold family K06889 K06889; uncharacterized protein
D APH_1345 putative membrane protein K06890 K06890; uncharacterized protein
D APH_0671 conserved hypothetical protein K07018 K07018; uncharacterized protein
D APH_0625 immunogenic protein K07080 K07080; uncharacterized protein
D APH_0052 conserved hypothetical protein K09791 K09791; uncharacterized protein
D APH_0775 conserved hypothetical protein K09985 K09985; uncharacterized protein
D APH_0062 conserved hypothetical protein K09987 K09987; uncharacterized protein
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#[ KO | BRITE | KEGG2 | KEGG ]
#Last updated: June 20, 2024