+E Ubiquitin system KO
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Ubiquitin System - Luidia clathrata (European starfish)
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AUbiquitins and ubiquitin-like proteins
B Ubiquitins
C 117296146 polyubiquitin-C K08770 UBC; ubiquitin C
C 117301479 ubiquitin-60S ribosomal protein L40 K02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e
C 117291593 ubiquitin-40S ribosomal protein S27a K02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae
B Ubiquitin-like proteins (UBLs)
C 117305973 NEDD8 K12158 NEDD8; ubiquitin-like protein Nedd8
C 117292929 ubiquitin-like protein FUBI K02983 RP-S30e; small subunit ribosomal protein S30e
C 117293621 small ubiquitin-related modifier 2-like K12160 SUMO; small ubiquitin-related modifier
C 117300137 small ubiquitin-related modifier-like K12160 SUMO; small ubiquitin-related modifier
C 117289757 gamma-aminobutyric acid receptor-associated protein-like 2 K08341 GABARAP; GABA(A) receptor-associated protein
C 117302343 gamma-aminobutyric acid receptor-associated protein K08341 GABARAP; GABA(A) receptor-associated protein
C 117292514 autophagy protein 12-like K08336 ATG12; ubiquitin-like protein ATG12
C 117303222 ubiquitin-related modifier 1-like K12161 URM1; ubiquitin related modifier 1
C 117293316 ubiquitin-fold modifier 1 isoform X1 K12162 UFM1; ubiquitin-fold modifier 1
C 117293320 ubiquitin-like protein 3 K28515 UBL3; membrane-anchored ubiquitin-fold protein
C 117303782 AN1-type zinc finger protein 4-like K12163 ZFAND4; AN1-type zinc finger protein 4
#
AUbiquitin-activating enzymes (E1)
B Ubiquitin activating enzyme
C 117304782 ubiquitin-like modifier-activating enzyme 1 K03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]
B UBL-activating enzymes
C 117298267 SUMO-activating enzyme subunit 1-like K10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]
C 117289401 SUMO-activating enzyme subunit 2-like K10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]
C 117307348 NEDD8-activating enzyme E1 catalytic subunit-like isoform X1 K10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]
C 117289121 NEDD8-activating enzyme E1 regulatory subunit-like K04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit
C 117305766 adenylyltransferase and sulfurtransferase MOCS3-like isoform X1 K11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]
C 117291256 ubiquitin-like modifier-activating enzyme 5 K12164 UBA5; ubiquitin-like modifier-activating enzyme 5
C 117295994 ubiquitin-like modifier-activating enzyme 6 K10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]
C 117306901 ubiquitin-like modifier-activating enzyme ATG7 isoform X1 K08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7
#
AUbiquitin-conjugating enzymes (E2)
B Ubiquitin-conjugating enzymes
C 117293876 ubiquitin-conjugating enzyme E2 A K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
C 117289419 probable ubiquitin-conjugating enzyme E2 C K06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]
C 117303671 ubiquitin-conjugating enzyme E2-17 kDa-like K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 117303697 ubiquitin-conjugating enzyme E2-17 kDa K06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]
C 117291418 ubiquitin-conjugating enzyme E2 E1-like K20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]
C 117290283 ubiquitin-conjugating enzyme E2 G1-like K10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]
C 117291641 ubiquitin-conjugating enzyme E2 G2-like K04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]
C 117303673 ubiquitin-conjugating enzyme E2 H K10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]
C 117297033 ubiquitin-conjugating enzyme E2 J1-like K10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]
C 117302163 ubiquitin-conjugating enzyme E2 J2-like K04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]
C 117293423 ubiquitin-conjugating enzyme E2 K-like K04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]
C 117290361 ubiquitin-conjugating enzyme E2 L3-like K04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]
C 117304969 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C 117289490 ubiquitin-conjugating enzyme E2 Q1-like isoform X1 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 117289937 uncharacterized protein LOC117289937 K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 117296038 ubiquitin-conjugating enzyme E2 Q2-like K10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]
C 117295432 ubiquitin-conjugating enzyme E2 R2-like K02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]
C 117292999 ubiquitin-conjugating enzyme E2 S-like K10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]
C 117299226 ubiquitin-conjugating enzyme E2 T-like isoform X1 K13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]
C 117297424 ubiquitin-conjugating enzyme E2 U-like K10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]
C 117304815 ubiquitin-conjugating enzyme E2 W-like K10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]
C 117291804 baculoviral IAP repeat-containing protein 6-like isoform X1 K10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]
B UBL-conjugating enzymes
C 117292618 SUMO-conjugating enzyme UBC9-B-like K10577 UBE2I; ubiquitin-conjugating enzyme E2 I
C 117291433 NEDD8-conjugating enzyme UBE2F-like isoform X1 K10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]
C 117305044 NEDD8-conjugating enzyme ubc12-like K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 117305293 NEDD8-conjugating enzyme Ubc12-like K10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]
C 117298497 ubiquitin-like-conjugating enzyme ATG3 K08343 ATG3; ubiquitin-like-conjugating enzyme ATG3
C 117297933 ubiquitin-like-conjugating enzyme ATG10 K17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10
C 117301506 ubiquitin-fold modifier-conjugating enzyme 1 K12165 UFC1; ufm1-conjugating enzyme 1
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AUbiquitin ligases (E3)
B HECT type E3
C 117293408 ubiquitin-protein ligase E3A-like K10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]
C 117290330 ubiquitin-protein ligase E3B-like K10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]
C 117297631 ubiquitin-protein ligase E3C-like K10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]
C 117296581 E3 ubiquitin-protein ligase E3D-like isoform X1 K20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]
C 117292662 E3 ubiquitin-protein ligase SMURF2-like K04678 SMURF; E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
C 117289127 NEDD4-like E3 ubiquitin-protein ligase WWP1 K05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]
C 117298842 E3 ubiquitin-protein ligase TRIP12-like isoform X1 K10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
C 117295643 E3 ubiquitin-protein ligase NEDD4-like isoform X1 K10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]
C 117306587 E3 ubiquitin-protein ligase HUWE1-like isoform X1 K10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]
C 117297176 apoptosis-resistant E3 ubiquitin protein ligase 1-like isoform X1 K22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]
C 117300691 E3 ubiquitin-protein ligase UBR5-like isoform X1 K10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]
C 117295332 probable E3 ubiquitin-protein ligase HERC1 isoform X1 K10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]
C 117293972 E3 ubiquitin-protein ligase HERC2-like K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
C 117303698 probable E3 ubiquitin-protein ligase HERC3 K10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]
C 117299869 E3 ubiquitin-protein ligase HECW2-like isoform X1 K12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]
C 117293349 E3 ubiquitin-protein ligase HECTD1-like K12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]
C 117294442 probable E3 ubiquitin-protein ligase HECTD2 K12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]
C 117297836 E3 ubiquitin-protein ligase HECTD3-like K12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]
C 117290432 LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HECTD4 K17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]
C HECT type E3 associated proteins
D 117293934 NEDD4 family-interacting protein 1-like K25839 NDFIP; NEDD4 family-interacting protein
D 117292814 UPF0472 protein C16orf72 homolog K27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1
B U-box type E3
C 117301596 ubiquitin conjugation factor E4 A-like K10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]
C 117302155 ubiquitin conjugation factor E4 B-like isoform X1 K10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]
C 117292802 STIP1 homology and U box-containing protein 1-like K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 117290042 RING-type E3 ubiquitin-protein ligase PPIL2-like K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
C 117290822 pre-mRNA-processing factor 19-like K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
C 117294539 RING finger protein 37-like K10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]
B Single Ring-finger type E3
C BRE1 proteins
D 117290428 E3 ubiquitin-protein ligase BRE1A-like K10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]
C CBL proteins
D 117301445 E3 ubiquitin-protein ligase CBL-B-B-like isoform X1 K04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]
C SINA (Seven in absentia) proteins
D 117288310 E3 ubiquitin-protein ligase Siah1-like K04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]
C Ligand of Numb proteins
D 117299602 ligand of Numb protein X 2-like K10692 LNX1_2; ligand of Numb protein X 1/2 [EC:2.3.2.27]
D 117306155 E3 ubiquitin-protein ligase PDZRN3-like K15682 PDZRN3_4; ligand of Numb protein X 3/4 [EC:2.3.2.27]
C March proteins
D 117303606 E3 ubiquitin-protein ligase MARCH8-like K10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1/8 [EC:2.3.2.27]
D 117291155 uncharacterized protein LOC117291155 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 117304944 E3 ubiquitin-protein ligase MARCH2-like isoform X1 K10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2/3 [EC:2.3.2.27]
D 117294618 E3 ubiquitin-protein ligase MARCH5-like K10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]
D 117288839 E3 ubiquitin-protein ligase MARCH6-like K10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]
C MDM2/MDM4 proteins
C NFX1 proteins
D 117300300 transcriptional repressor NF-X1-like K12236 NFX1; transcriptional repressor NF-X1
D 117293401 NF-X1-type zinc finger protein NFXL1-like K15683 NFXL1; NF-X1-type zinc finger protein NFXL1
C Pellino proteins
D 117296987 E3 ubiquitin-protein ligase pellino homolog 2-like K11964 PELI; pellino [EC:2.3.2.27]
C Peripheral membrane proteins
D 117302423 peroxisome biogenesis factor 10-like K13346 PEX10; peroxin-10
D 117290171 peroxisome assembly protein 12-like K13345 PEX12; peroxin-12
D 117302402 peroxisome biogenesis factor 2-like K06664 PEX2; peroxin-2
C RBR proteins
D 117296826 E3 ubiquitin-protein ligase parkin-like isoform X1 K04556 PARK2; parkin [EC:2.3.2.31]
D 117291376 ankyrin repeat and IBR domain-containing protein 1-like K11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]
D 117295709 E3 ubiquitin-protein ligase arih1-like isoform X1 K11968 ARIH1; ariadne-1 [EC:2.3.2.31]
D 117306943 E3 ubiquitin-protein ligase ARIH2-like isoform X1 K11969 ARIH2; ariadne-2 [EC:2.3.2.31]
D 117289035 ranBP-type and C3HC4-type zinc finger-containing protein 1-like isoform X1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
D 117293660 E3 ubiquitin-protein ligase RNF14-like isoform X1 K11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]
D 117300672 E3 ubiquitin-protein ligase RNF19A-like K11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]
D 117290767 E3 ubiquitin-protein ligase RNF34-like isoform X1 K20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]
D 117304465 probable E3 ubiquitin-protein ligase RNF144A-A K11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]
D 117300849 probable E3 ubiquitin-protein ligase RNF217 K11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]
D 117301181 probable E3 ubiquitin-protein ligase RNF217 K11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]
C TRAF proteins
D 117302925 TNF receptor-associated factor 3-like K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
D 117292195 TNF receptor-associated factor 6-like K03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]
D 117288758 E3 ubiquitin-protein ligase TRAF7-like K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
D 117292478 E3 ubiquitin-protein ligase TRAF7-like isoform X1 K10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]
C TRIM/RBCC proteins
D 117293237 tripartite motif-containing protein 2-like K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 117298605 tripartite motif-containing protein 3-like K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 117299921 tripartite motif-containing protein 2-like K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 117300640 tripartite motif-containing protein 3-like K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 117303047 tripartite motif-containing protein 2-like K11997 TRIM2_3; tripartite motif-containing protein 2/3
D 117299110 E3 ubiquitin-protein ligase TRIM9-like isoform X1 K10649 TRIM9_67; tripartite motif-containing protein 9/67
D 117297607 E3 ubiquitin-protein ligase TRIM23-like K07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]
D 117305152 E3 ubiquitin-protein ligase TRIM33-like isoform X1 K08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]
D 117302338 E3 ubiquitin-protein ligase TRIM36-like isoform X1 K12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]
D 117289909 E3 ubiquitin-protein ligase TRIM37-like K10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]
D 117303438 tripartite motif-containing protein 45-like K12021 TRIM45; tripartite motif-containing protein 45
D 117289140 E3 ubiquitin-protein ligase TRIM71-like K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
C UBR box proteins
D 117288795 E3 ubiquitin-protein ligase UBR2-like isoform X1 K10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]
D 117299981 E3 ubiquitin-protein ligase ubr3-like K11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]
D 117303093 E3 ubiquitin-protein ligase UBR4-like K10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]
D 117298851 putative E3 ubiquitin-protein ligase UBR7 K11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]
C ATL proteins
C Other single Ring-finger type E3
D 117289723 E3 ubiquitin-protein ligase AMFR-like K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 117292747 bifunctional apoptosis regulator-like K15684 BFAR; bifunctional apoptosis regulator
D 117296849 E3 ubiquitin-protein ligase XIAP-like K16060 BIRC2_3; baculoviral IAP repeat-containing protein 2/3
D 117290323 BRCA1-associated protein-like K10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]
D 117303708 E3 ubiquitin-protein ligase Hakai-like K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D 117295762 E3 ubiquitin-protein ligase CCNB1IP1-like K10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]
D 117290055 E3 ubiquitin-protein ligase CHFR-like K10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]
D 117299420 CCR4-NOT transcription complex subunit 4-like K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
D 117287959 protein sneaky-like K22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]
D 117290317 E3 ubiquitin-protein ligase DTX4-like isoform X1 K06058 DTX; deltex [EC:2.3.2.27]
D 117296288 E3 ubiquitin-protein ligase FANCL-like K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
D 117294531 E3 ubiquitin-protein ligase KCMF1-like K22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]
D 117302955 E3 ubiquitin-protein ligase LRSAM1-like K10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]
D 117296851 E3 ubiquitin-protein ligase listerin-like isoform X1 K22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]
D 117297879 mitogen-activated protein kinase kinase kinase 1-like K04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]
D 117295419 RNA-binding protein MEX3B-like K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
D 117299782 E3 ubiquitin-protein ligase MIB1-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 117302398 E3 ubiquitin-protein ligase MIB2-like isoform X1 K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 117302545 E3 ubiquitin-protein ligase MIB2-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 117302557 E3 ubiquitin-protein ligase MIB2-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 117302769 E3 ubiquitin-protein ligase MIB2-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 117304789 E3 ubiquitin-protein ligase MIB1-like K10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]
D 117306806 probable E3 ubiquitin-protein ligase makorin-1 isoform X1 K15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]
D 117290972 mitochondrial ubiquitin ligase activator of nfkb 1-A-like K15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]
D 117293291 E3 ubiquitin-protein ligase MYCBP2-like isoform X1 K10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]
D 117289351 E3 ubiquitin-protein ligase MYLIP-A-like K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 117291689 E3 ubiquitin-protein ligase MYLIP-like K10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]
D 117294391 protein neuralized-like K01931 NEUR; protein neuralized [EC:2.3.2.27]
D 117304796 E3 ubiquitin-protein ligase RAD18-like K10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]
D 117296696 V(D)J recombination-activating protein 1-like K10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]
D 117303493 E3 ubiquitin-protein ligase COP1-like isoform X1 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
D 117299488 E3 ubiquitin-protein ligase RFWD3-like K15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]
D 117296074 E3 ubiquitin-protein ligase RING2-like K10695 RNF1_2; E3 ubiquitin-protein ligase RNF1/2 [EC:2.3.2.27]
D 117295092 E3 ubiquitin-protein ligase RNF4-like K22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]
D 117290431 E3 ubiquitin-protein ligase RNF185-like K10666 RNF5_185; E3 ubiquitin-protein ligase RNF5/185 [EC:2.3.2.27]
D 117295057 E3 ubiquitin-protein ligase RNF8-like K10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]
D 117290638 RING finger protein 10-like isoform X1 K26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]
D 117298062 RING finger protein 11-like K11980 RNF11; E3 ubiquitin-protein ligase RNF11
D 117298432 E3 ubiquitin-protein ligase RNF13-like isoform X1 K15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]
D 117290544 zinc finger CCCH domain-containing protein 13-like K10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]
D 117302941 uncharacterized protein LOC117302941 K15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]
D 117295001 RING finger protein 44-like isoform X1 K19041 RNF38_44; E3 ubiquitin-protein ligase RNF38/44 [EC:2.3.2.27]
D 117291105 E3 ubiquitin-protein ligase NRDP1-like K11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]
D 117295024 E3 ubiquitin-protein ligase RNF103-like K15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]
D 117295896 E3 ubiquitin-protein ligase RNF126-like K11982 RNF115_126; E3 ubiquitin-protein ligase RNF115/126 [EC:2.3.2.27]
D 117294071 RING finger protein 121-like K15698 RNF121_175; RING finger protein 121/175
D 117294820 RING finger protein 24-like K15699 RNF122; RING finger protein 122
D 117295179 E3 ubiquitin-protein ligase RNF139-like K15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]
D 117294754 RING finger protein 145-like K23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]
D 117304705 E3 ubiquitin-protein ligase rnf146-like K15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]
D 117292460 E3 ubiquitin-protein ligase MGRN1-like isoform X1 K25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]
D 117289482 E3 ubiquitin-protein ligase RNF166-like K17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]
D 117297513 E3 ubiquitin-protein ligase RNF170-like K15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]
D 117303977 E3 ubiquitin-protein ligase RNF181-like K22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]
D 117297624 E3 ubiquitin-protein ligase RNF220-like K25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]
D 117290229 RING finger and transmembrane domain-containing protein 2-like K28516 RNFT2; E3 ubiquitin-protein ligase RNFT2
D 117294182 U4/U6.U5 tri-snRNP-associated protein 1-like K11984 SART1; U4/U6.U5 tri-snRNP-associated protein 1
D 117296900 E3 ubiquitin-protein ligase SHPRH-like K15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]
D 117293433 E3 ubiquitin-protein ligase SH3RF1-like isoform X1 K12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]
D 117300076 helicase-like transcription factor K15711 SMARCA3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]
D 117291107 E3 ubiquitin-protein ligase synoviolin B-like isoform X1 K10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]
D 117294267 E3 ubiquitin-protein ligase TM129-like K22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]
D 117302084 E3 ubiquitin-protein ligase TRAIP-like K11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]
D 117297543 E3 ubiquitin-protein ligase UHRF1-like K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 117300882 E3 ubiquitin-protein ligase UHRF2-like K10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]
D 117292577 putative E3 ubiquitin-protein ligase UNKL isoform X1 K23047 UNKL; E3 ubiquitin-protein ligase UNKL [EC:2.3.2.27]
D 117292568 E3 ubiquitin-protein ligase ZNF598-like K22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]
D 117288757 E3 ubiquitin-protein ligase znrf2-like K10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1/2 [EC:2.3.2.27]
D 117300072 uncharacterized protein LOC117300072 K15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]
D 117290652 E3 ubiquitin-protein ligase RGLG4-like K16280 RGLG; E3 ubiquitin-protein ligase RGLG [EC:2.3.2.27]
B Atypical E3
C 117304414 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
C 117288521 probable E3 ubiquitin-protein ligase IRF2BPL K22383 IRF2BP; interferon regulatory factor 2-binding protein
B UBL E3 ligases
C 117293427 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
C 117295426 E3 SUMO-protein ligase PIAS2-like K04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]
C 117300980 E3 SUMO-protein ligase NSE2-like K22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]
C 117296190 zinc finger BED domain-containing protein 4-like isoform X1 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C 117297020 E3 UFM1-protein ligase 1-like isoform X1 K22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]
C 117298408 DCN1-like protein 1 K17822 DCUN1D1_2; DCN1-like protein 1/2
C 117292085 DCN1-like protein 3 K17823 DCUN1D3; DCN1-like protein 3
C 117293775 DCN1-like protein 5 K17824 DCUN1D4_5; DCN1-like protein 4/5
B Multi subunit type E3
C SCF complex
D Ring finger protein
E 117293427 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 117287769 cullin-1-like K03347 CUL1; cullin 1
D Adaptor protein
E 117304093 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit (F-box)
E 117295167 F-box/WD repeat-containing protein 11-like isoform X1 K03362 FBXW1_11; F-box and WD-40 domain protein 1/11
E 117300801 F-box/WD repeat-containing protein 2-like K10261 FBXW2; F-box and WD-40 domain protein 2
E 117294830 F-box/WD repeat-containing protein 4-like K10262 FBXW4; F-box and WD-40 domain protein 4
E 117303387 F-box/WD repeat-containing protein 5-like K10263 FBXW5; F-box and WD-40 domain protein 5
E 117288585 F-box/WD repeat-containing protein 7-like K10260 FBXW7; F-box and WD-40 domain protein 7
E 117293650 F-box/WD repeat-containing protein 7-like isoform X1 K10260 FBXW7; F-box and WD-40 domain protein 7
E 117306895 F-box/WD repeat-containing protein 7-like K10260 FBXW7; F-box and WD-40 domain protein 7
E 117298005 F-box/WD repeat-containing protein 9-like K10265 FBXW9; F-box and WD-40 domain protein 9
E 117292255 CMT1A duplicated region transcript 1 protein-like K10266 FBXW10; F-box and WD-40 domain protein 10
E 117297435 S-phase kinase-associated protein 2-like K03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)
E 117287894 F-box/LRR-repeat protein 20-like K10268 FBXL2_20; F-box and leucine-rich repeat protein 2/20
E 117299872 F-box/LRR-repeat protein 4-like K10270 FBXL4; F-box and leucine-rich repeat protein 4
E 117306993 F-box/LRR-repeat protein 5-like isoform X1 K10271 FBXL5; F-box and leucine-rich repeat protein 5
E 117303108 F-box/LRR-repeat protein 6-like K10272 FBXL6; F-box and leucine-rich repeat protein 6
E 117288397 F-box/LRR-repeat protein 7-like K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 117297744 F-box/LRR-repeat protein 20-like K10273 FBXL7; F-box and leucine-rich repeat protein 7
E 117289608 F-box/LRR-repeat protein 8-like K10274 FBXL8; F-box and leucine-rich repeat protein 8
E 117293942 F-box/LRR-repeat protein 4-like isoform X1 K10275 FBXL9; F-box and leucine-rich repeat protein 9
E 117290232 lysine-specific demethylase 2B-like isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
E 117297425 F-box/LRR-repeat protein 12-like K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 117297680 F-box/LRR-repeat protein 16-like K10278 FBXL12; F-box and leucine-rich repeat protein 12
E 117306774 dynein regulatory complex subunit 6-like isoform X1 K10279 FBXL13; dynein regulatory complex subunit 6
E 117306841 F-box/LRR-repeat protein 14-like K10280 FBXL14; F-box and leucine-rich repeat protein 14
E 117288182 F-box/LRR-repeat protein 20-like K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 117303685 F-box/LRR-repeat protein 15-like K10281 FBXL15; F-box and leucine-rich repeat protein 15
E 117292292 F-box/LRR-repeat protein 16-like K10282 FBXL16; F-box and leucine-rich repeat protein 16
E 117288511 F-box/LRR-repeat protein 17-like K10283 FBXL17; F-box and leucine-rich repeat protein 17
E 117288914 uncharacterized protein LOC117288914 K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 117307025 F-box/LRR-repeat protein 18-like K10284 FBXL18; F-box and leucine-rich repeat protein 18
E 117293878 F-box/LRR-repeat protein 3-like K10287 FBXL21; F-box and leucine-rich repeat protein 21
E 117292818 cyclin-F-like K10289 CCNF; F-box protein 1 (cyclin F)
E 117291775 F-box only protein 3-like K10290 FBXO3; F-box protein 3
E 117297994 F-box only protein 4-like isoform X1 K10291 FBXO4; F-box protein 4
E 117307119 F-box only protein 7-like K10293 FBXO7; F-box protein 7
E 117293510 F-box only protein 8-like K10294 FBXO8; F-box protein 8
E 117301011 F-box only protein 9-like K10295 FBXO9; F-box protein 9
E 117290298 F-box only protein 11-like isoform X1 K10297 FBXO11; F-box protein 11
E 117289380 F-box only protein 15-like K10298 FBXO15; F-box protein 15
E 117300667 F-box only protein 16-like isoform X1 K10299 FBXO16; F-box protein 16
E 117306361 F-box DNA helicase 1-like K10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]
E 117290881 F-box only protein 21-like isoform X1 K10301 FBXO21; F-box protein 21
E 117295914 F-box only protein 22-like K10302 FBXO22; F-box protein 22
E 117303822 tetraspanin-5-like K10303 FBXO23; F-box protein 23
E 117303856 tetraspanin-5-like K10303 FBXO23; F-box protein 23
E 117304622 F-box only protein 25-like isoform X1 K10305 FBXO25_32; F-box protein 25/32
E 117302279 F-box only protein 6-like K10102 FBXO27; F-box protein 27
E 117297264 F-box only protein 28-like K10306 FBXO28; F-box protein 28
E 117289678 F-box only protein 31-like K10308 FBXO31; F-box protein 31
E 117295775 F-box only protein 33-like K10310 FBXO33; F-box protein 33
E 117298831 F-box only protein 36-like K10312 FBXO36; F-box protein 36
E 117290111 uncharacterized protein LOC117290111 K10314 FBXO39; F-box protein 39
E 117299490 F-box only protein 30-like K10315 FBXO40; F-box protein 40
E 117302349 F-box only protein 42-like K10317 FBXO42; F-box protein 42
E 117298230 F-box/SPRY domain-containing protein 1-like K10319 FBXO45; F-box protein 45
E 117305478 F-box only protein 47-like K10321 FBXO47; F-box protein 47
C Cul2 complex
D Ring finger protein
E 117293427 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 117300146 cullin-2-like K03870 CUL2; cullin 2
D Adoptor protein
E 117304471 elongin-C K03872 ELOC; elongin-C
E 117289988 elongin-B-like K03873 ELOB; elongin-B
D Target recognizing subunit
E 117304591 von Hippel-Lindau disease tumor suppressor-like K03871 VHL; von Hippel-Lindau disease tumor supressor
E 117295527 leucine-rich repeat protein 1-like K10348 LRR1; LRR-repeat protein 1
E 117296129 protein fem-1 homolog C-like K25805 FEM1A_C; protein fem-1 homolog A/C
E 117295518 protein fem-1 homolog B-like K10349 FEM1B; protein fem-1 homolog B
E 117290744 amyloid protein-binding protein 2-like K25806 APPBP2; amyloid protein-binding protein 2
E 117290722 kelch domain-containing protein 2-like K25807 KLHDC2; kelch domain-containing protein 2
E 117292889 kelch domain-containing protein 3-like K25808 KLHDC3; kelch domain-containing protein 3
E 117303135 kelch domain-containing protein 10-like K25809 KLHDC10; kelch domain-containing protein 10
E 117307437 kelch domain-containing protein 10-like isoform X1 K25809 KLHDC10; kelch domain-containing protein 10
E 117297573 protein zyg-11 homolog B-like isoform X1 K10350 ZYG11; Zyg-11 protein
E 117303504 protein zer-1 homolog K10350 ZYG11; Zyg-11 protein
E 117303805 zinc finger SWIM domain-containing protein 8-like K25207 ZSWIM8; zinc finger SWIM domain-containing protein 8
C Cul3 complex
D Ring finger protein
E 117293427 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 117298431 cullin-3-like K03869 CUL3; cullin 3
D Adoptor and target recognizing subunit (BTB)
E 117293425 kelch-like protein 5 K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 117293944 kelch-like protein diablo K10442 KLHL1_4_5; kelch-like protein 1/4/5
E 117303726 kelch-like protein 2 isoform X1 K10443 KLHL2_3; kelch-like protein 2/3
E 117293319 kelch-like protein 8 isoform X1 K10446 KLHL8; kelch-like protein 8
E 117302274 kelch-like protein 13 K10447 KLHL9_13; kelch-like protein 9/13
E 117302510 kelch-like protein 9 K10447 KLHL9_13; kelch-like protein 9/13
E 117300238 kelch-like protein 10 K10448 KLHL10; kelch-like protein 10
E 117289312 kelch-like protein 20 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 117300673 kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 117302486 kelch-like protein 17 K10454 KLHL17; kelch-like protein 17 (actinfilin)
E 117287766 kelch-like protein 18 isoform X1 K10455 KLHL18; kelch-like protein 18
E 117297400 kelch-like ECH-associated protein 1B K10456 KLHL19; kelch-like protein 19
E 117287795 kelch-like protein 3 K10457 KLHL20; kelch-like protein 20
E 117288798 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 117300334 kelch-like protein diablo K10457 KLHL20; kelch-like protein 20
E 117303333 kelch-like protein 20 K10457 KLHL20; kelch-like protein 20
E 117304394 kelch-like protein 24 K10458 KLHL21; kelch-like protein 21
E 117296065 kelch-like protein 24 K10461 KLHL24_35; kelch-like protein 24/35
E 117304410 kelch-like protein 24 K10461 KLHL24_35; kelch-like protein 24/35
E 117289660 kelch-like protein 25 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 117305376 kelch-like protein 18 K10462 KLHL25_37; kelch-like protein 25/37 (ectoderm-neural cortex protein)
E 117299345 kelch-like protein diablo K10463 KLHL26; kelch-like protein 26
E 117297496 actin-binding protein IPP-like K13956 IPP; actin-binding protein IPP
E 117291409 kelch-like protein 28 K10464 KLHL28; kelch-like protein 28
E 117288535 kelch-like protein 29 K10465 KLHL29; kelch-like protein 29
E 117298220 kelch-like protein 24 K10465 KLHL29; kelch-like protein 29
E 117304606 kelch-like protein 24 K10465 KLHL29; kelch-like protein 29
E 117298007 kelch-like protein 30 K10466 KLHL30; kelch-like protein 30
E 117295660 kelch-like protein diablo K10467 KLHL31; kelch-like protein 31
E 117295838 BTB/POZ domain-containing protein 1-like K10477 BTBD1_2; BTB/POZ domain-containing protein 1/2
E 117292511 BTB/POZ domain-containing protein 6-B-like K10478 BTBD3_6; BTB/POZ domain-containing protein 3/6
E 117298544 BTB/POZ domain-containing protein 7-like K10479 BTBD7; BTB/POZ domain-containing protein 7
E 117299880 BTB/POZ domain-containing protein 9-like K10481 BTBD9; BTB/POZ domain-containing protein 9
E 117307261 BTB/POZ domain-containing protein 10-like K10482 BTBD10; BTB/POZ domain-containing protein 10
E 117303872 germ cell-less protein-like 1 isoform X1 K10485 BTBD13; BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1)
E 117294707 BTB/POZ domain-containing protein 16-like K10487 BTBD16; BTB/POZ domain-containing protein 16
E 117294490 myoneurin-like K10500 ZBTB17; zinc finger and BTB domain-containing protein 17
E 117304315 ankyrin repeat and BTB/POZ domain-containing protein 1-like K10520 ABTB1; ankyrin repeat and BTB/POZ domain-containing protein 1
E 117305073 ankyrin repeat and BTB/POZ domain-containing protein BTBD11-like isoform X1 K10521 ABTB2; ankyrin repeat and BTB/POZ domain-containing protein 2
E 117294929 rho-related BTB domain-containing protein 2-like K07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1/2
E 117289949 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3-like K15074 BACURD; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein
E 117289724 BTB/POZ domain-containing protein kctd15-like K21754 KCTD1_15; BTB/POZ domain-containing protein KCTD1/15
E 117292379 BTB/POZ domain-containing protein KCTD5-like K21914 KCTD2_5_17; BTB/POZ domain-containing protein KCTD2/5/17
E 117291756 BTB/POZ domain-containing protein KCTD3-like isoform X1 K21915 KCTD3; BTB/POZ domain-containing protein KCTD3
E 117298568 BTB/POZ domain-containing protein KCTD6-like K21916 KCTD6; BTB/POZ domain-containing protein KCTD6
E 117293712 BTB/POZ domain-containing protein KCTD8-like K21918 KCTD8_12_16; BTB/POZ domain-containing protein KCTD8/12/16
E 117295043 BTB/POZ domain-containing protein KCTD9-like isoform X1 K21919 KCTD9; BTB/POZ domain-containing protein KCTD9
E 117298567 BTB/POZ domain-containing protein KCTD4-like K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 117298728 BTB/POZ domain-containing protein KCTD1-like K21922 KCTD21; BTB/POZ domain-containing protein KCTD21
E 117291669 diablo homolog, mitochondrial-like K10522 DIABLO; diablo
E 117287985 speckle-type POZ protein-like K10523 SPOP; speckle-type POZ protein
E 117290381 leucine-zipper-like transcriptional regulator 1 K23330 LZTR1; leucine-zipper-like transcriptional regulator 1
C Cul4 complex
D Ring finger protein
E 117293427 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
E 117298438 cullin-4A-like K10609 CUL4; cullin 4
D Adoptor protein
E 117305193 DNA damage-binding protein 1-like K10610 DDB1; DNA damage-binding protein 1
D Target recognizing subunit (DCAF)
E 117302741 DNA damage-binding protein 2-like isoform X1 K10140 DDB2; DNA damage-binding protein 2
E 117297927 DNA excision repair protein ERCC-8-like K10570 ERCC8; DNA excision repair protein ERCC-8
E 117295259 DET1 homolog K10571 DET1; de-etiolated-1
E 117303493 E3 ubiquitin-protein ligase COP1-like isoform X1 K10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]
E 117296136 DET1- and DDB1-associated protein 1-like K11792 DDA1; DET1- and DDB1-associated protein 1
E 117304504 protein cereblon-like K11793 CRBN; cereblon
E 117289701 short transient receptor potential channel 4-associated protein-like K11796 TRPC4AP; Trpc4-associated protein
E 117306473 DDB1- and CUL4-associated factor 1-like K11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]
E 117288934 denticleless protein homolog isoform X1 K11790 DTL; denticleless
E 117293048 DDB1- and CUL4-associated factor 4-like K11799 DCAF4; DDB1- and CUL4-associated factor 4
E 117299837 DDB1- and CUL4-associated factor 5-like K11800 DCAF5; DDB1- and CUL4-associated factor 5
E 117296948 DDB1- and CUL4-associated factor 6-like isoform X1 K11795 DCAF6; DDB1- and CUL4-associated factor 6
E 117299382 DDB1- and CUL4-associated factor 7 K11805 DCAF7; DDB1- and CUL4-associated factor 7
E 117301421 DDB1- and CUL4-associated factor 8-like K11804 DCAF8; DDB1- and CUL4-associated factor 8
E 117297071 WD and tetratricopeptide repeats protein 1-like K11807 WDTC1; WD and tetratricopeptide repeats protein 1
E 117294982 DDB1- and CUL4-associated factor 10-like K11802 DCAF10; DDB1- and CUL4-associated factor 10
E 117289242 DDB1- and CUL4-associated factor 11-like K11801 DCAF11; DDB1- and CUL4-associated factor 11
E 117295434 DDB1- and CUL4-associated factor 12-like K11803 DCAF12; DDB1- and CUL4-associated factor 12
E 117300655 DDB1- and CUL4-associated factor 13-like K11806 DCAF13; DDB1- and CUL4-associated factor 13
E 117302705 DDB1- and CUL4-associated factor 17-like K23331 DCAF17; DDB1- and CUL4-associated factor 17
E 117296495 bromodomain and WD repeat-containing protein 3-like K11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1/3
E 117288949 WD repeat-containing protein 26-like K22382 WDR26; WD repeat-containing protein 26
E 117297942 WD repeat-containing protein 70-like K24752 WDR70; WD repeat-containing protein 70
E 117299390 WD repeat-containing protein 76-like isoform X1 K24755 WDR76; WD repeat-containing protein 76
C Cul5 complex
D Ring finger protein
E 117298958 RING-box protein 2-like K10611 RBX2; RING-box protein 2
D Cullin
E 117296871 cullin-5-like K10612 CUL5; cullin 5
D Adoptor protein
E 117304471 elongin-C K03872 ELOC; elongin-C
E 117289988 elongin-B-like K03873 ELOB; elongin-B
D Target recognizing subunit
E 117292276 suppressor of cytokine signaling 2-like K04695 SOCS2; suppressor of cytokine signaling 2
E 117293872 uncharacterized protein LOC117293872 K04698 SOCS5; suppressor of cytokine signaling 5
E 117289772 suppressor of cytokine signaling 7-like K04699 SOCS6_7; suppressor of cytokine signaling 6/7
E 117288146 ankyrin repeat and SOCS box protein 1-like K10323 ASB1; ankyrin repeat and SOCS box protein 1
E 117298936 ankyrin repeat and SOCS box protein 3-like K10325 ASB3; ankyrin repeat and SOCS box protein 3
E 117305772 ankyrin repeat and SOCS box protein 3-like K10325 ASB3; ankyrin repeat and SOCS box protein 3
E 117296044 ankyrin repeat and SOCS box protein 7-like K10329 ASB7; ankyrin repeat and SOCS box protein 7
E 117291809 ankyrin repeat and SOCS box protein 8-like K10330 ASB8; ankyrin repeat and SOCS box protein 8
E 117306882 ankyrin repeat and SOCS box protein 9-like isoform X1 K10331 ASB9; ankyrin repeat and SOCS box protein 9
E 117306849 ankyrin repeat and SOCS box protein 13-like K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 117307390 ankyrin repeat and SOCS box protein 13-like isoform X1 K10335 ASB13; ankyrin repeat and SOCS box protein 13
E 117290416 WD repeat and SOCS box-containing protein 1-like K10341 WSB1; WD repeat and SOCS box-containing protein 1
E 117302216 protein gustavus-like K10343 SPSB1_4; SPRY domain-containing SOCS box protein 1/4
E 117292767 SPRY domain-containing SOCS box protein 3-like K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 117292990 SPRY domain-containing SOCS box protein 3-like K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 117304408 SPRY domain-containing SOCS box protein 3-like K10345 SPSB3; SPRY domain-containing SOCS box protein 3
E 117292281 ras-related protein Rab-40C-like isoform X1 K07928 RAB40; Ras-related protein Rab-40
E 117288805 RING finger and SPRY domain-containing protein 1-like K23332 RSPRY1; RING finger and SPRY domain-containing protein 1
C Cul7 complex
D Ring finger protein
E 117293427 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
E 117304093 S-phase kinase-associated protein 1-like K03094 SKP1; S-phase kinase-associated protein 1
D Target recognizing subunit
C Cul8 complex
D Ring finger protein
E 117293427 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
D Adaptor protein
D Target recognizing subunit
C Cul9 complex
D Ring finger protein
E 117293427 RING-box protein 1 K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
D Cullin
C APC/C
D Ring finger protein
E 117295786 anaphase-promoting complex subunit 11 K03358 APC11; anaphase-promoting complex subunit 11
D Cullin
E 117303414 anaphase-promoting complex subunit 2-like isoform X1 K03349 APC2; anaphase-promoting complex subunit 2
D Target recognizing subunit
E 117298050 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 117298516 cell division cycle protein 20 homolog K03363 CDC20; cell division cycle 20, cofactor of APC complex
E 117297432 fizzy-related protein homolog isoform X1 K03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex
D Other subunits
E 117292125 anaphase-promoting complex subunit 1-like K03348 APC1; anaphase-promoting complex subunit 1
E 117291243 cell division cycle protein 27 homolog K03350 APC3; anaphase-promoting complex subunit 3
E 117294730 anaphase-promoting complex subunit 4-like K03351 APC4; anaphase-promoting complex subunit 4
E 117303032 anaphase-promoting complex subunit 5-like K03352 APC5; anaphase-promoting complex subunit 5
E 117298479 cell division cycle protein 16 homolog K03353 APC6; anaphase-promoting complex subunit 6
E 117306329 anaphase-promoting complex subunit 7-like K03354 APC7; anaphase-promoting complex subunit 7
E 117294698 cell division cycle protein 23 homolog K03355 APC8; anaphase-promoting complex subunit 8
E 117294762 anaphase-promoting complex subunit 10-like K03357 APC10; anaphase-promoting complex subunit 10
E 117303279 anaphase-promoting complex subunit CDC26-like K03359 APC12; anaphase-promoting complex subunit 12
E 117301321 anaphase-promoting complex subunit 13-like K12456 APC13; anaphase-promoting complex subunit 13
E 117293764 anaphase-promoting complex subunit 15-like K25228 APC15; anaphase-promoting complex subunit 15
C BRCC complex
D 117298480 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 117300070 BRCA1-associated RING domain protein 1-like K10683 BARD1; BRCA1-associated RING domain protein 1
D 117305893 BRISC and BRCA1-A complex member 2-like K12173 BRE; BRCA1-A complex subunit BRE
D 117299310 DNA repair protein RAD51 homolog A-like K04482 RAD51; DNA repair protein RAD51
C KPC complex
C LUBAC complex
D 117289035 ranBP-type and C3HC4-type zinc finger-containing protein 1-like isoform X1 K10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]
C CTLH complex
D 117294810 E3 ubiquitin-protein ligase RMND5A-like K23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]
D 117289049 ran-binding protein 9-like K23334 RANBP9_10; Ran-binding protein 9/10
D 117291866 armadillo repeat-containing protein 8-like K23336 ARMC8; armadillo repeat-containing protein 8
D 117304384 muskelin-like K23337 MKLN1; muskelin
D 117294592 E3 ubiquitin-protein transferase MAEA-like K18624 MAEA; macrophage erythroblast attacher
D 117292252 glucose-induced degradation protein 4 homolog K23335 GID4; glucose-induced degradation protein 4
D 117299394 glucose-induced degradation protein 8 homolog isoform X1 K23338 GID8; glucose-induced degradation protein 8
D 117293609 protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 117298028 protein yippee-like 5 K23339 YPEL5; protein yippee-like 5
D 117288949 WD repeat-containing protein 26-like K22382 WDR26; WD repeat-containing protein 26
C ERAD complex
D 117289723 E3 ubiquitin-protein ligase AMFR-like K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 117306486 transmembrane and ubiquitin-like domain-containing protein 2 K23340 TMUB; transmembrane and ubiquitin-like domain-containing protein
D 117303741 erlin-1-like isoform X1 K23341 ERLIN; erlin
C LMBR1L-GP78-UBAC2 complex
D 117287772 protein LMBR1L-like K25215 LMBR1L; protein LMBR1L
D 117289723 E3 ubiquitin-protein ligase AMFR-like K10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]
D 117300872 ubiquitin-associated domain-containing protein 2-like isoform X1 K25216 UBAC2; ubiquitin-associated domain-containing protein 2
C STUB1-CHIC2 complex
D 117292802 STIP1 homology and U box-containing protein 1-like K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
D 117306333 cysteine-rich hydrophobic domain-containing protein 2-like K28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2
C SLX5-SLX8 complex
C Multi subunit type E3 associated proteins
D 117300685 cullin-associated NEDD8-dissociated protein 1-like isoform X1 K17263 CAND1; cullin-associated NEDD8-dissociated protein 1
D 117298915 COMM domain-containing protein 1-like K22557 COMMD1; COMM domain containing 1
D 117298481 COMM domain-containing protein 2-like K22558 COMMD2; COMM domain containing 2
D 117299840 COMM domain-containing protein 3-like K22559 COMMD3; COMM domain containing 3
D 117288286 COMM domain-containing protein 4-like K22560 COMMD4; COMM domain containing 4
D 117293956 COMM domain-containing protein 5-like K22561 COMMD5; COMM domain containing 5
D 117293682 COMM domain-containing protein 6-like K22562 COMMD6; COMM domain containing 6
D 117306371 COMM domain-containing protein 7-like isoform X1 K22563 COMMD7; COMM domain containing 7
D 117293675 COMM domain-containing protein 8-like K22564 COMMD8; COMM domain containing 8
D 117305225 COMM domain-containing protein 9-like K22565 COMMD9; COMM domain containing 9
D 117295941 COMM domain-containing protein 10-like K22566 COMMD10; COMM domain containing 10
D 117293632 coiled-coil domain-containing protein 22 homolog K23343 CCDC22; coiled-coil domain-containing protein 22
D 117294869 DDRGK domain-containing protein 1-like K23344 DDRGK1; DDRGK domain-containing protein 1
D 117303240 glomulin-like K23345 GLMN; glomulin
D 117303054 influenza virus NS1A-binding protein-like isoform X1 K15046 IVNS1ABP; influenza virus NS1A-binding protein
D 117298459 UBX domain-containing protein 7-like K24350 UBXN7; UBX domain-containing protein 7
D 117295599 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 117296880 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 117298366 parkin coregulated gene protein homolog K26163 PACRG; parkin coregulated gene protein
D 117296876 SH3 domain-containing protein Dlish-like K26546 Dlish; SH3 domain-containing protein Dlish
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ADeubiquitinating enzyme (DUB)
B Ubiquitin-specific proteases (UBPs)
C UCH
D 117307245 ubiquitin carboxyl-terminal hydrolase BAP1-like K08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]
D 117293543 ubiquitin carboxyl-terminal hydrolase isozyme L3-like K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
D 117303228 ubiquitin carboxyl-terminal hydrolase isozyme L5-like K05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]
C UBP/USP
D 117301702 uncharacterized protein LOC117301702 K11833 USP2; ubiquitin carboxyl-terminal hydrolase 2 [EC:3.4.19.12]
D 117296133 ubiquitin carboxyl-terminal hydrolase 3-like K11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]
D 117302387 ubiquitin carboxyl-terminal hydrolase 5-like K11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12]
D 117289943 ubiquitin carboxyl-terminal hydrolase 32-like isoform X1 K11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12]
D 117292200 ubiquitin carboxyl-terminal hydrolase 7-like K11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]
D 117288445 ubiquitin carboxyl-terminal hydrolase 8-like K11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]
D 117297528 ubiquitin carboxyl-terminal hydrolase 24-like K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 117298795 probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X1 K11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12]
D 117289287 ubiquitin carboxyl-terminal hydrolase 10-A-like K11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]
D 117293435 ubiquitin carboxyl-terminal hydrolase 12-B-like K11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12]
D 117304632 ubiquitin carboxyl-terminal hydrolase 14-like K11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]
D 117306792 ubiquitin carboxyl-terminal hydrolase 15-like K21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]
D 117297080 ubiquitin carboxyl-terminal hydrolase 16-like K11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12]
D 117306229 ubiquitin carboxyl-terminal hydrolase 19-like K11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]
D 117303163 ubiquitin carboxyl-terminal hydrolase 20-like K11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12]
D 117292938 ubiquitin carboxyl-terminal hydrolase 22-like K11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12]
D 117301337 ubiquitin carboxyl-terminal hydrolase 25-like isoform X1 K11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]
D 117292778 ubiquitin carboxyl-terminal hydrolase 37-like K11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12]
D 117292264 ubiquitin carboxyl-terminal hydrolase 31-like K11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]
D 117291457 ubiquitin carboxyl-terminal hydrolase 34-like isoform X1 K11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]
D 117293447 ubiquitin carboxyl-terminal hydrolase 38-like isoform X1 K11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12]
D 117299437 ubiquitin carboxyl-terminal hydrolase 44-like K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 117299643 ubiquitin carboxyl-terminal hydrolase 44-B-like K11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12]
D 117291315 ubiquitin carboxyl-terminal hydrolase 47-like isoform X1 K11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]
D 117302529 ubiquitin carboxyl-terminal hydrolase 48-like K11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]
D 117303776 inactive ubiquitin carboxyl-terminal hydrolase 54-like isoform X1 K27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]
C OTU
D 117306733 ubiquitin thioesterase OTUB1-like K09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]
D 117302448 OTU domain-containing protein 3-like K13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]
D 117302133 OTU domain-containing protein 5-A-like K12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]
D 117289324 deubiquitinase OTUD6B-like K18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]
D 117295410 OTU domain-containing protein 7A-like isoform X1 K11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]
D 117296993 uncharacterized protein LOC117296993 isoform X1 K11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]
D 117299456 deubiquitinating protein VCIP135-like K11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]
D 117294551 ubiquitin thioesterase zranb1-B-like K11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]
C MJD
D 117288530 ataxin-3-like K11863 ATXN3; Ataxin-3 [EC:3.4.22.-]
D 117292178 josephin-2-like K15235 JOSD; josephin [EC:3.4.19.12]
C MINDY
D 117299436 ubiquitin carboxyl-terminal hydrolase MINDY-2-like K01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1/2 [EC:3.4.19.12]
D 117298960 inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B-like isoform X1 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 117300047 probable ubiquitin carboxyl-terminal hydrolase MINDY-4 K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
D 117300063 ubiquitin carboxyl-terminal hydrolase MINDY-3-like K22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3/4 [EC:3.4.19.12]
C JAMM
D 117298480 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 117291171 MPN domain-containing protein-like K24173 MPND; MPN domain-containing protein
D 117300992 26S proteasome non-ATPase regulatory subunit 14 K03030 PSMD14; 26S proteasome regulatory subunit N11
D 117303820 STAM-binding protein-like K11866 STAMBP; STAM-binding protein [EC:3.4.19.12]
C PPPDE
D 117299540 deubiquitinase DESI2-like K22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]
C ZUFSP
C BRISC complex
D 117294264 BRISC complex subunit Abraxas 2-like K20799 FAM175B; BRISC complex subunit Abro1
D 117297363 BRISC and BRCA1-A complex member 1-like K20776 BABAM; BRISC and BRCA1-A complex member 1
D 117298480 lys-63-specific deubiquitinase BRCC36-like K11864 BRCC3; BRCA1/BRCA2-containing complex subunit 3 [EC:3.4.19.-]
D 117305893 BRISC and BRCA1-A complex member 2-like K12173 BRE; BRCA1-A complex subunit BRE
B UBL-specific proteases (ULPs)
C 117300347 sentrin-specific protease 1-like isoform X1 K08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]
C 117307048 sentrin-specific protease 8-like K08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]
C 117293543 ubiquitin carboxyl-terminal hydrolase isozyme L3-like K05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]
C COP9 signalosome (CSN) complex
D 117292510 COP9 signalosome complex subunit 1-like isoform X1 K12175 GPS1; COP9 signalosome complex subunit 1
D 117296043 COP9 signalosome complex subunit 2 K12176 COPS2; COP9 signalosome complex subunit 2
D 117304102 COP9 signalosome complex subunit 3-like K12177 COPS3; COP9 signalosome complex subunit 3
D 117303877 COP9 signalosome complex subunit 4-like K12178 COPS4; COP9 signalosome complex subunit 4
D 117304535 COP9 signalosome complex subunit 5 K09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]
D 117298517 COP9 signalosome complex subunit 6-like K12179 COPS6; COP9 signalosome complex subunit 6
D 117302234 COP9 signalosome complex subunit 7b-like isoform X1 K12180 COPS7; COP9 signalosome complex subunit 7
D 117291903 COP9 signalosome complex subunit 8-like K12181 COPS8; COP9 signalosome complex subunit 8
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 28, 2025