+C Peptidases and inhibitors KO #

  Peptidases and Inhibitors - Actinoplanes sp. SE50/110

% ! AAspartic peptidases B Family A1: pepsin family B Family A2: retropepsin family B Family A5: thermopsin family B Family A8: signal peptidase II family C ACPL_1772 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36] B Family A22: presenilin family B Family A24: type IV prepilin peptidase family C ACPL_1125 hofD; leader peptidase (prepilin peptidase) / N-methyltransferase K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] C ACPL_5898 Type 4 prepilin-like proteins leader peptide-processing enzyme K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-] B Family A25: gpr protease family B Family A26: omptin family B Family A28 B Family A31: HybD endopeptidase family B Family A36 # ACysteine peptidases B Family C1: papain family B Family C2: calpain family B Family C3: picornain family B Family C4: NIa protease family B Family C5 B Family C9 B Family C10: streptopain family B Family C11: clostripain family B Family C12: ubiquitin C-terminal hydrolase family B Family C13: legumain family B Family C14: caspase family B Family C15: pyroglutamyl peptidase I family B Family C16 B Family C19: ubiquitin-specific protease family B Family C25: gingipain family B Family C26: gamma-glutamyl hydrolase family C ACPL_873 guaA; GMP synthase (glutamine-hydrolysing) K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] C ACPL_7227 putative glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase C ACPL_7228 putative glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase B Family C27 B Family C30 B Family C37 B Family C39 B Family C40 C ACPL_1269 D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase cwlS K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C ACPL_3029 yibP-like uncharacterized protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C ACPL_332 ydhO-like uncharacterized protein K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C ACPL_420 Cortactin-binding protein 2 K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] C ACPL_8254 iap; Gamma-DL-glutamyl hydrolase K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-] B Family C44 C ACPL_236 purF; amidophosphoribosyltransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14] C ACPL_1813 gltB; glutamate synthase (NADPH/NADH) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13] C ACPL_7564 glmS; glucosamine-fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C ACPL_838 glmS; glucosamine-fructose-6-phosphate aminotransferase (isomerizing) K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] C ACPL_1006 asparagine synthase (glutamine-hydrolysing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] C ACPL_5068 asn1; asparagine synthase (glutamine-hydrolysing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] C ACPL_6235 asnH; asparagine synthase (glutamine-hydrolysing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] C ACPL_6846 asnB; asparagine synthase (glutamine-hydrolysing) K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] B Family C45 B Family C46: hedgehog family B Family C47: staphopain family B Family C48: Ulp1 endopeptidase family B Family C50: separase family B Family C54: Aut2 peptidase family B Family C55: YopJ protease family B Family C56: PfpI endopeptidase family C ACPL_1347 pfpI; protease I K05520 yhbO; deglycase [EC:3.5.1.124] C ACPL_2763 protease I K05520 yhbO; deglycase [EC:3.5.1.124] B Family C57: vaccinia virus I7 peptidase family B Family C58 B Family C59 B Family C60 B Family C63 B Family C64 B Family C65 B Family C67 B Family C69 B Family C70 B Family C75 B Family C76 B Family C78 B Family C79 B Family C82 B Family C83 B Family C85 B Family C86 B Family C88 B Family C89 B Family C97 B Family C98 B Family C110 # AGlutamic peptidases B Family G1 B Family G4 B Family G5: prenyl protease 2 family C ACPL_2829 abortive infection protein K07052 K07052; CAAX protease family protein C ACPL_3178 abortive infection protein K07052 K07052; CAAX protease family protein C ACPL_3236 hypothetical protein K07052 K07052; CAAX protease family protein C ACPL_3566 Lysostaphin resistance protein A K07052 K07052; CAAX protease family protein C ACPL_5663 abortive infection protein K07052 K07052; CAAX protease family protein C ACPL_6209 putative protease K07052 K07052; CAAX protease family protein # AMetallo peptidases B Family M1 C ACPL_1323 pepN; Aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] C ACPL_1381 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] C ACPL_3330 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] C ACPL_7483 pepN; aminopeptidase N K01256 pepN; aminopeptidase N [EC:3.4.11.2] B Family M2 B Family M3 B Family M4: thermolysin family B Family M5: mycolysin family B Family M6: immune inhibitor A family C ACPL_472 ina; immune inhibitor A K09607 ina; immune inhibitor A [EC:3.4.24.-] B Family M7: snapalysin family B Family M8: leishmanolysin family B Family M9 B Family M10 B Family M12: astacin/adamalysin family B Family M13: neprilysin family B Family M14: carboxypeptidase A family B Family M15: zinc D-Ala-D-Ala carboxypeptidase family C ACPL_1556 vanY; peptidase M15B and M15C dd-carboxypeptidase VanY/endolysin K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] C ACPL_278 D-alanyl-D-alanine carboxypeptidase K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14] B Family M16: pitrilysin family C ACPL_5052 putative zinc protease K07263 pqqL; zinc protease [EC:3.4.24.-] C ACPL_7360 putative zinc protease K07263 pqqL; zinc protease [EC:3.4.24.-] C ACPL_7361 peptidase subunit K07263 pqqL; zinc protease [EC:3.4.24.-] C ACPL_7615 putative zinc protease K07263 pqqL; zinc protease [EC:3.4.24.-] C ACPL_7616 peptidase subunit K07263 pqqL; zinc protease [EC:3.4.24.-] C ACPL_864 putative zinc protease K07263 pqqL; zinc protease [EC:3.4.24.-] B Family M17: leucyl aminopeptidase family C ACPL_1620 pepB; leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] C ACPL_7843 pepA; leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1] B Family M18 B Family M19: membrane dipeptidase family C ACPL_2983 membrane dipeptidase K01273 DPEP; membrane dipeptidase [EC:3.4.13.19] B Family M20 C ACPL_2329 glutamate carboxypeptidase K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11] C ACPL_3781 cpg2; glutamate carboxypeptidase K01295 cpg; glutamate carboxypeptidase [EC:3.4.17.11] C ACPL_2279 succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C ACPL_6404 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C ACPL_7630 dapE; succinyl-diaminopimelate desuccinylase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] C ACPL_4018 Beta-Ala-His dipeptidase K23980 tpdA; cysteinylglycine-S-conjugate dipeptidase [EC:3.4.13.23] B Family M23 C ACPL_2115 putative metalloprotease K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] C ACPL_333 Glycyl-glycine endopeptidase ALE-1 K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] C ACPL_8141 L-Ala-D-Glu endopeptidase K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-] B Family M24 C ACPL_2606 map; methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C ACPL_7224 map; methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C ACPL_804 map; methionyl aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18] C ACPL_1905 pepP; X-Pro aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] B Family M26 B Family M27 B Family M28: aminopeptidase Y family C ACPL_3300 aminopeptidase Y K19702 E3.4.11.24; aminopeptidase S [EC:3.4.11.24] B Family M29: aminopeptidase T family C ACPL_6605 ampS; aminopeptidase K19689 ampS; aminopeptidase [EC:3.4.11.-] B Family M32: carboxypeptidase Taq family B Family M34: anthrax lethal factor family B Family M35: deuterolysin family C ACPL_4120 peptidyl-Lys metalloendopeptidase K08646 MEP; peptidyl-Lys metalloendopeptidase [EC:3.4.24.20] B Family M36: fungalysin family C ACPL_661 hypothetical protein K01417 MEP; extracellular elastinolytic metalloproteinase [EC:3.4.24.-] B Family M38: beta-aspartyl dipeptidase family B Family M41: FtsH endopeptidase family C ACPL_2109 AAA ATPase central domain protein K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] C ACPL_8090 ftsH; cell division protease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-] B Family M42: glutamyl aminopeptidase family B Family M43: cytophagalysin family B Family M44 B Family M48: Ste24 endopeptidase family C ACPL_748 heat shock protein HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] C ACPL_967 Zn-dependent protease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-] B Family M49: dipeptidyl-peptidase III family B Family M50: S2P protease family C ACPL_3194 hypothetical protein K16922 yydH; putative peptide zinc metalloprotease protein C ACPL_7538 cyclic nucleotide-binding protein K16922 yydH; putative peptide zinc metalloprotease protein B Family M54 B Family M55: DppA aminopeptidase family B Family M56 C ACPL_3030 hypothetical protein K02172 blaR1; bla regulator protein blaR1 B Family M67 B Family M72 B Family M73 B Family M74 B Family M80 B Family M82 C ACPL_247 membrane protein-like protein K24131 prsW; protease PrsW [EC:3.4.-.-] C ACPL_5470 hypothetical protein K24131 prsW; protease PrsW [EC:3.4.-.-] C ACPL_7980 Protease prsW K24131 prsW; protease PrsW [EC:3.4.-.-] B Family M85 B Family M88 B Family M90 B Family M98 # AAsparagine peptide lyases B Family N1 B Family N8 # AMixed peptidases B Family P1: DmpA aminopeptidase family B Family P2 # ASerine peptidases B Family S1: chymotrypsin family C ACPL_2903 peptidase S1 and S6 chymotrypsin/Hap K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C ACPL_7539 pepD; PepD-like putative serine protease K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C ACPL_7841 peptidase S1 and S6 chymotrypsin/Hap K08372 pepD; putative serine protease PepD [EC:3.4.21.-] C ACPL_7193 streptogrisin C K18546 sprC; streptogrisin C [EC:3.4.21.-] C ACPL_6799 sprD; Streptogrisin-D K18547 sprD; streptogrisin D [EC:3.4.21.-] B Family S3: togavirin family B Family S6 B Family S7: flavivirin family B Family S8: subtilisin family C ACPL_4119 aprA; peptidase S8/S53 subtilisin kexin sedolisin K01342 aprE; subtilisin [EC:3.4.21.62] C ACPL_6704 protease K14645 K14645; serine protease [EC:3.4.21.-] C ACPL_1597 Furin K14743 mycP; membrane-anchored mycosin MYCP [EC:3.4.21.-] C ACPL_4726 aprX; peptidase S8 and S53 subtilisin kexin sedolisin K17734 aprX; serine protease AprX [EC:3.4.21.-] B Family S9: prolyl oligopeptidase family C ACPL_7650 dipeptidyl-peptidase 4 K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5] C ACPL_393 ptrB; oligopeptidase B K01354 ptrB; oligopeptidase B [EC:3.4.21.83] B Family S10 B Family S11: D-Ala-D-Ala carboxypeptidase A family C ACPL_5026 dacC; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] C ACPL_6659 dac; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5/6) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4] B Family S12: D-Ala-D-Ala carboxypeptidase B family B Family S13: D-Ala-D-Ala peptidase C family C ACPL_8094 dac; D-alanyl-D-alanine carboxypeptidase / D-alanyl-D-alanine-endopeptidase (penicillin-binding protein 4) K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-] B Family S14: ClpP endopeptidase family C ACPL_1353 ATP-dependent Clp protease, protease subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C ACPL_1354 ATP-dependent Clp protease, protease subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C ACPL_1841 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] C ACPL_7529 ATP-dependent Clp protease, protease subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] B Family S15 B Family S16: lon protease family C ACPL_7600 PDZ domain-containing protein K07177 K07177; Lon-like protease B Family S21: assemblin family B Family S24: LexA family C ACPL_2149 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] C ACPL_5550 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] C ACPL_7151 lexA; LexA-like transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88] B Family S26: signal peptidase I family C ACPL_4250 lepB; Signal peptidase I T K03100 lepB; signal peptidase I [EC:3.4.21.89] C ACPL_6959 Signal peptidase I T K03100 lepB; signal peptidase I [EC:3.4.21.89] C ACPL_7275 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C ACPL_7276 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C ACPL_7497 sip2; signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89] C ACPL_824 zan; Zonadhesin K13280 SEC11; signal peptidase I [EC:3.4.21.89] B Family S28 B Family S31 B Family S32 B Family S33 C ACPL_4738 proline iminopeptidase K01259 pip; proline iminopeptidase [EC:3.4.11.5] C ACPL_6143 ephA; epoxide hydrolase K27108 ephA_B; epoxide hydrolase A/B [EC:3.3.2.-] B Family S41: C-terminal processing peptidase family C ACPL_4397 putative ctpA-like serine protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102] B Family S45 C ACPL_7002 penicillin amidase K01434 pac; penicillin G amidase [EC:3.5.1.11] B Family S49: protease IV family B Family S50 B Family S51 C ACPL_3786 cphB; cyanophycinase domain protein K13282 cphB; cyanophycinase [EC:3.4.15.6] C ACPL_6521 cphB; cyanophycinase K13282 cphB; cyanophycinase [EC:3.4.15.6] B Family S53 B Family S54: Rhomboid family B Family S55: SpoIVB peptidase family B Family S62 B Family S66 B Family S77: phage prohead processing peptidase family B Family S78 # AThreonine peptidases B Family T1: proteasome family C ACPL_5242 prcA; proteasome alpha subunit K03432 psmA; proteasome alpha subunit [EC:3.4.25.1] C ACPL_5243 prcB; proteasome beta subunit K03433 psmB; proteasome beta subunit [EC:3.4.25.1] B Family T2 B Family T3: gamma-glutamyltransferase family C ACPL_6641 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] C ACPL_733 ggt; gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] # APeptidases of unknown catalytic type B Family U32 B Family U62 C ACPL_7651 TldDlike protein K03568 tldD; TldD protein # APeptidase inhibitors B Family I1: Kazal family B Family I2: Kunitz - BPTI family B Family I4: serpin family B Family I11: ecotin family B Family I17: WAP-type family B Family I25: cystatin family B Family I27: calpastatin family B Family I32: IAP family B Family I34: IA3 family B Family I35: timp family B Family I39: alpha2M family B Family I47: latexin family B Family I49: proSAAS family B Family I51: IC family B Family I57: staphostatin B family B Family I63 B Family I80 B Family I87 B Family I93 ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 20, 2025 #
Classification taken and modified from MEROPS