+D Transcription factors KO
#
Transcription Factors - Actinoplanes sp. SE50/110
%
!
AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
C AP-1(-like) components, Fos
C AP-1(-like) components, Maf
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
C CREB
C C/EBP-like factors
C bZIP/PAR
C Plant bZIP factors
C ZIP only
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
C Myogenic transcription factors
C Achaete-Scute
C Tal/Twist/Atonal/Hen, Lymphoid factors
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
C Tal/Twist/Atonal/Hen, HEN
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
C Hairy, Fungal regulators
C Factors with PAS domain
C Yabby
C INO
C HLH domain only
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
C Cell cycle controlling factors, Myc
C Cell cycle controlling factors, Mad/Max
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
C RF-X
C AP-2 (bHSH)
B Zinc finger
C Cys4 thyroid hormone receptor-like
C Cys4 hepatocyte nuclear factor 4-like
C Cys4 estrogen receptor-like
C Cys4 nerve growth factor IB-like
C Cys4 Fushi tarazu-F1-like
C Cys4 germ cell nuclear factor
C Cys4 Knirps/DAX1-like
C Cys4 GATA-factors
C Cys2His2 SP/KLF family and related proteins
C Cys2His2 GLI-like
C Cys2His2 Snail
C Cys2His2 BTB-ZF factors
C Cys2His2 BED
C Cys2His2 PRDM
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
C Cys2HisCys zinc factors
C Cys3His zinc factors
C Cys2CysHis zinc factors
C CXXC CpG-binding proteins
D ACPL_5787 DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
B Helix-turn-helix
C Homeo domain ANTP: HOXL
C Homeo domain ANTP: NKL
C Homeo domain Paired-related
C Homeo domain LIM
C Homeo domain POU
C Homeo domain SINE
C Homeo domain ZF
C Homeo domain CUT
C Homeo domain PROS
C Homeo domain TALE
C Homeo domain other
C Fork head/winged helix developmental regulators
C Fork head/winged helix tissue-specific regulators
C Fork head/winged helix cell cycle-controlling factors, E2F
C Fork head/winged helix cell cycle-controlling factors, DP
C Fork head/winged helix other regulators
C Stork head/winged helix factors
C Heat shock factors
C Tryptophan clusters Myb, Myb-factors
C Tryptophan clusters Myb, Myb-like factors
C Tryptophan clusters Ets-type
C Tryptophan clusters interferon-regulating factors
C TEA domain
C ARID
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
C RHR (Rel homology region) Ankyrin only
C RHR (Rel homology region) NF-AT
C STAT
C p53
C MADS-box regulators of differentiation, MEF-2
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
C SAND domain-containing proteins
C TATA-binding proteins
C HMG SOX
C HMG TCF-1
C HMG TOX
C HMG2-related
C UBF
C Other HMG box factors
C Heteromeric CCAAT factors
C Grainyhead
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
C Cold-shock domain factors, FRG Y2-like
C Runt
C MYRF
B Other transcription factors
C HMGI(Y)
C NUPR
C Pocket domain Rb
C Pocket domain CBP
C T-box
C DMRT
C LRRFIP
C TCP
C AP2/ERF
C WRKY
C LOB
C GRAS
C Copper-fist proteins fungal regulators
C Others
#
AProkaryotic type
B Helix-turn-helix
C AraC family
D ACPL_7689 AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
D ACPL_1231 ftrA; HTH-type transcriptional regulator glxA K13633 ftrA; AraC family transcriptional regulator, transcriptional activator FtrA
D ACPL_2743 HTH-type transcriptional regulator glxA K13633 ftrA; AraC family transcriptional regulator, transcriptional activator FtrA
C LysR family
D ACPL_4251 metR; putative RuBisCO transcriptional regulator K03576 metR; LysR family transcriptional regulator, regulator for metE and metH
D ACPL_7632 Chromosome initiation inhibitor K05596 argP; LysR family transcriptional regulator, arginine and lysine transport system/DNA replication regulator
C DeoR family
D ACPL_7996 Glycerol-3-phosphate regulon repressor K02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor
D ACPL_6374 Putative aga operon transcriptional repressor K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor
C LacI family
D ACPL_1034 HTH-type transcriptional repressor purR K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_2162 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_2307 HTH-type transcriptional repressor purR K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_2484 bxlR; LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_4661 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_5369 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_5383 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_5673 LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_6039 PurR-like HTH-type transcriptional repressor K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_625 celR; HTH-type transcriptional regulator celR K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_6673 rbsR; LacI family transcriptional regulator K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D ACPL_3868 LacI family transcription regulator K05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG
D ACPL_6842 LacI family transcriptional regulator K05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG
D ACPL_7018 transcriptional regulator, LacI family K05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG
C GntR family
D ACPL_3023 yvoA; Mannosyl-D-glycerate transport/metabolism system repressor mngR K03710 K03710; GntR family transcriptional regulator
D ACPL_5261 HTH-type transcriptional regulator frlR K03710 K03710; GntR family transcriptional regulator
D ACPL_654 HTH-type transcriptional repressor yvoA K03710 K03710; GntR family transcriptional regulator
D ACPL_1794 GntR family transcriptional regulator / MocR family aminotransferase K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
D ACPL_1927 yisV-like uncharacterized HTH-type transcriptional regulator K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
C TetR/AcrR family
D ACPL_4452 tetR; putative HTH-type transcriptional regulator yttP K09017 rutR; TetR/AcrR family transcriptional regulator
D ACPL_3332 mtrR; HTH-type transcriptional regulator mtrR K19736 aefR; TetR/AcrR family transcriptional regulator, regulator of autoinduction and epiphytic fitness
D ACPL_7668 putative HTH-type transcriptional regulator K19736 aefR; TetR/AcrR family transcriptional regulator, regulator of autoinduction and epiphytic fitness
D ACPL_3049 TetR family transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D ACPL_311 yxaF-like uncharacterized HTH-type transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D ACPL_4526 dhaR; HTH-type transcriptional repressor dhaR K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D ACPL_5909 yxaF-like uncharacterized HTH-type transcriptional regulator K16137 nemR; TetR/AcrR family transcriptional regulator, transcriptional repressor for nem operon
D ACPL_3934 ydeS-like uncharacterized HTH-type transcriptional regulator K18301 mexL; TetR/AcrR family transcriptional regulator, mexJK operon transcriptional repressor
D ACPL_4236 yezE-like uncharacterized HTH-type transcriptional regulator K19335 bdcR; TetR/AcrR family transcriptional regulator, repressor for divergent bdcA
D ACPL_5453 TetR family transcriptional regulator K21961 ethR; TetR/AcrR family transcriptional regulator, ethionamide resistance regulator
D ACPL_1896 mtrR; HTH-type transcriptional regulator mtrR K21962 acnR; TetR/AcrR family transcriptional regulator, transcriptional repressor of aconitase
D ACPL_6074 tcmR; HTH-type transcriptional regulator tcmR K24699 mftR; TetR/AcrR family transcriptional regulator, regulator of mycofactocin system
D ACPL_2966 HTH-type transcriptional regulator betI K23778 rcdA; TetR/AcrR family transcriptional regulator, regulator of biofilm formation and stress response
C Lrp/AsnC family
D ACPL_2476 putative HTH-type transcriptional regulator K03718 asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA
D ACPL_2813 putative HTH-type transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D ACPL_3104 Leucine-responsive regulatory protein K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D ACPL_415 putative HTH-type transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
C LuxR family
D ACPL_3989 HTH-type transcriptional regulator malT K03556 malT; LuxR family transcriptional regulator, maltose regulon positive regulatory protein
D ACPL_3991 HTH-type transcriptional regulator malT K03556 malT; LuxR family transcriptional regulator, maltose regulon positive regulatory protein
C MarR family
D ACPL_4565 HTH-type transcriptional regulator hpr K03712 marR; MarR family transcriptional regulator, multiple antibiotic resistance protein MarR
D ACPL_1571 Organic hydroperoxide resistance transcriptional regulator K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
D ACPL_4356 ohrR; HTH-type transcriptional regulator sarZ K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
C MerR family
D ACPL_8260 soxR; Redox-sensitive transcriptional activator soxR K13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR
D ACPL_203 hspR; Redox-sensitive transcriptional activator soxR K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D ACPL_7238 putative heavy metal-dependent transcriptional regulator K13640 hspR; MerR family transcriptional regulator, heat shock protein HspR
D ACPL_252 ycgE-like uncharacterized HTH-type transcriptional regulator K22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator
C Fur family
D ACPL_1433 fur; Ferric uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D ACPL_7953 Ferric uptake regulation protein K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D ACPL_2234 hypothetical protein K22297 furA; Fur family transcriptional regulator, stress-responsive regulator
D ACPL_7819 fur; Ferric uptake regulation protein K22297 furA; Fur family transcriptional regulator, stress-responsive regulator
C IclR family
D ACPL_2354 kdgR; Pectin degradation repressor protein kdgR K02624 pcaR; IclR family transcriptional regulator, pca regulon regulatory protein
C CRP/FNR family
D ACPL_1681 Anaerobic regulatory protein K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
D ACPL_8104 hlyX; Regulatory protein hlyX K10914 crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein
C Rrf2 family
C ArsR family
D ACPL_1828 arsR; ArsR family transcriptional regulator K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D ACPL_212 cadC; Cadmium efflux system accessory-like protein K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D ACPL_4644 Cadmium efflux system accessory protein K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D ACPL_1434 putative HTH-type transcriptional regulator K22298 smtB; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor
C XRE family
D ACPL_5156 transcriptional regulator, XRE family K21686 prpR; XRE family transcriptional regulator, fatty acid utilization regulator
D ACPL_7185 XRE family transcriptional regulator K27043 clgR; XRE family transcriptional regulator, stress-response regulator
C PadR family
D ACPL_1966 uncharacterized protein K10947 K10947; PadR family transcriptional regulator
D ACPL_2208 Coproporphyrinogen 3 oxidase, aerobic K10947 K10947; PadR family transcriptional regulator
D ACPL_4249 hypothetical protein K10947 K10947; PadR family transcriptional regulator
D ACPL_4985 transcriptional regulator, PadR-like family K10947 K10947; PadR family transcriptional regulator
D ACPL_524 transcriptional regulator, PadR-like family K10947 K10947; PadR family transcriptional regulator
D ACPL_5432 uncharacterized protein K10947 K10947; PadR family transcriptional regulator
D ACPL_6985 PadR family transcriptional regulator, regulatory protein PadR K10947 K10947; PadR family transcriptional regulator
C Other families
D ACPL_7142 ideR; Iron-dependent repressor ideR K26252 dtxR; DtxR family transcriptional regulator, iron-dependent repressor
D ACPL_3031 copY; putative transcriptional regulator K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
D ACPL_7716 birA; BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D ACPL_569 nadR; Transcriptional regulator nadR K06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]
D ACPL_2062 yrhO-like uncharacterized protein K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D ACPL_7864 rex; AT-rich DNA-binding protein K01926 rex; redox-sensing transcriptional repressor
D ACPL_3277 hypothetical protein K27097 espR; ESX-1-secreted protein regulator
D ACPL_2874 putative HTH-type transcriptional regulator K07729 K07729; putative transcriptional regulator
D ACPL_4775 Putative HTH-type transcriptional regulatory protein K07729 K07729; putative transcriptional regulator
D ACPL_7350 putative HTH-type transcriptional regulator K07729 K07729; putative transcriptional regulator
B Ribbon-helix-helix
C CopG family
C Other families
D ACPL_5475 putA; 1-pyrroline-5-carboxylate dehydrogenase K13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
B Other transcription factors
C BglG family
C Others
D ACPL_1051 transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D ACPL_7558 transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D ACPL_7570 transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D ACPL_8115 transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D ACPL_866 wblB; transcription factor WhiB K18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D ACPL_7609 transcriptional regulatory protein WhiB-like WhiB7 K18958 whiB7; WhiB family transcriptional regulator, redox-sensing transcriptional regulator
D ACPL_711 Copper-sensing transcriptional repressor csoR K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D ACPL_6072 putative regulatory protein embR K22894 embR; SARP family transcriptional regulator, regulator of embCAB operon
D ACPL_8379 parB; putative chromosome-partitioning protein parB K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D ACPL_8038 CarD family transcriptional regulator K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
D ACPL_6417 argR; Arginine repressor K03402 argR; transcriptional regulator of arginine metabolism
D ACPL_1405 hrcA; Heat-inducible transcription repressor hrcA K03705 hrcA; heat-inducible transcriptional repressor
D ACPL_1652 phaN; phenylacetic acid degradation operon negative regulatory protein K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
D ACPL_7845 paaX; Phenylacetic acid degradation operon negative regulatory protein paaX K02616 paaX; phenylacetic acid degradation operon negative regulatory protein
D ACPL_6478 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D ACPL_5880 hypothetical protein K07733 alpA; prophage regulatory protein
D ACPL_7265 hypothetical protein K07733 alpA; prophage regulatory protein
D ACPL_1118 putative transcriptional regulator K07735 algH; putative transcriptional regulator
D ACPL_1771 DnaK suppressor-like protein K06204 dksA; RNA polymerase-binding transcription factor
D ACPL_3602 DnaK-like suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D ACPL_5291 DnaK-like suppressor protein K06204 dksA; RNA polymerase-binding transcription factor
D ACPL_7149 nrdR; NrdR-like transcriptional regulator K07738 nrdR; transcriptional repressor NrdR
D ACPL_1753 Protein mraZ K03925 mraZ; transcriptional regulator MraZ
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: August 21, 2025
#
Classification taken and modified from TRANSFAC 7.0