+F Repair protein KO #

  DNA Repair and Recombination Proteins - Actinoplanes sp. SE50/110

% ! AEukaryotic type B SSBR (single strand breaks repair) C Direct repair D ACPL_7690 methylated-DNA-[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D ACPL_8360 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D ACPL_257 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] C BER (base exicision repair) D DNA glycosylases E ACPL_847 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E ACPL_6387 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E ACPL_8051 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E ACPL_8102 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases D Long Patch-BER factors E DNA polymerase delta complex E DNA polymerase epsilon complex D Short Patch-BER factors D Other BER factors C NER (nucleotide excision repair) D GGR (global genome repair) factors E XPC-HR23B-CETN2 complex E Cul4-DDB2 complex E NER4 complex D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase II complex E Cul4-CSA complex E Other TCR factor D TFIIH complex E ACPL_526 DNA excision repair protein ERCC-3 K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4] D RPA (replication factor A) D Other NER factors C MMR (mismatch excision repair) D Mismatch and loop recognition factors D MutL homologs D DNA polymerase delta complex D RPA (replication factor A) D RFC (replication factor C) D Other MMR factors B DSBR (double strand breaks repair) C HR (homologous recombination) D MRN(MRX) complex D BRCA1-core complex D BRCA1-A complex D BRCA1-B complex D BRCA1-C complex D BRCA complex D RecA family proteins D Rad52 family proteins D Rad54 family proteins D RecQ family DNA helicases D Bloom's syndrome complex (BTR) D RPA (replication factor A) D Protein phosphatase 4 D AP-5 complex D SMC5-SMC6 complex D Other HR factors C NHEJ (non-homologous end-joining) D DNA-PK complex D MRX complex D DNA Ligase 4 complex D X-family DNA polymerases D Other NHEJ factors C FA (Fanconi anemia) pathway D FA core complex D FA core complex binding factors D Bloom's syndrome complex (BTR) D FANCD2-I complex D Downstream FA components D Other FA pathway factors C Other DSBR factors D Protein phosphatase 6 D Ubiquitin ligases D Others B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases C B-family DNA polymerases C A-family DNA polymerase C Rad6 epistasis group C Other TLS factors B Check point factors C Rad9-Hus1-Rad1 complex C HRAD17(Rad24)-RFC complex C Rad17-Mec3-Ddc1 complex C FPC (fork protection complex) C Triple T complex C BAG6-UBL4A-GET4 complex C Other check point factors B Other factors with a suspected DNA repair function C DNA polymerases C Nucleases C Helicases C PSO4 complex C Modulation of nucleotide pools D ACPL_133 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_1657 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_1923 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_7674 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_7752 7,8-dihydro-8-oxoguanine triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_7959 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_874 Nudix hydrolase 6 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_875 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_7108 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] # AProkaryotic type B SSBR (single strand breaks repair) C Direct repair D ACPL_7690 methylated-DNA-[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D ACPL_8360 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] D ACPL_257 phrB; deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3] D ACPL_7422 cry1; Cryptochrome-1 K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13] C BER (base exicision repair) D DNA glycosylases E ACPL_847 ung; uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27] E ACPL_1892 mug; TDG/mug DNA glycosylase family protein K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28] E ACPL_7174 DNA polymerase bacteriophage-type K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E ACPL_939 udgB; uracil-DNA glycosylase superfamily K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27] E ACPL_7689 AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21] E ACPL_6387 DNA-3-methyladenine glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21] E ACPL_8051 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31] E ACPL_7848 tag; DNA-3-methyladenine glycosylase I K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20] E ACPL_7316 fpg; formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E ACPL_8276 formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18] E ACPL_7182 nei1; endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E ACPL_7528 endonuclease VIII K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18] E ACPL_8102 nth; endonuclease III K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18] D AP endonucleases E ACPL_5312 xthA; exodeoxyribonuclease III K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] E ACPL_6791 endonuclease/exonuclease/phosphatase K01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2] E ACPL_1702 nfo; deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] E ACPL_8347 end; deoxyribonuclease IV K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2] E ACPL_1058 deoxyribonuclease V K05982 nfi; deoxyribonuclease V [EC:3.1.21.7] D RecJ D DNA ligase E ACPL_3138 ligA; DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E ACPL_7390 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D DNA polymerase I E ACPL_1827 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] C NER (nucleotide excision repair) D GGR (global genome repair) factors E ACPL_1848 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A E ACPL_1834 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B E ACPL_1850 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C E ACPL_7611 DNA helicase II / ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E ACPL_7625 DNA helicase II / ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E ACPL_8324 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E ACPL_889 pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E ACPL_1827 polA; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7] E ACPL_3138 ligA; DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E ACPL_7390 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D TCR (transcription coupled repair) factors E DNA-directed RNA polymerase complex (RNAP) F ACPL_773 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] F ACPL_774 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] F ACPL_811 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] F ACPL_6468 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] E TRCF (transcription-repair coupling factor) F ACPL_927 trcF; transcription-repair coupling factor (superfamily II helicase) K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] C MMR (mismatch excision repair) D Mismatch and loop recognition factors D Molecular matchmaker D Strand discrimination factor D DNA exonucleases E ACPL_7701 xseA; exodeoxyribonuclease VII large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6] E ACPL_7702 xseB; Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6] D DNA polymerase III holoenzyme E ACPL_1776 dnaE; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7] E ACPL_117 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] E ACPL_1392 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7] E ACPL_496 holB; DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7] E ACPL_1659 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E ACPL_6692 dnaQ; DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7] E ACPL_8134 dnaZ; DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7] D DNA ligase E ACPL_3138 ligA; DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E ACPL_7390 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] D Other MMR factors E ACPL_7611 DNA helicase II / ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E ACPL_7625 DNA helicase II / ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E ACPL_8324 UvrD/REP helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E ACPL_889 pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4] E ACPL_1290 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E ACPL_5803 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein E ACPL_8344 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein B DSBR (double strand breaks repair) C HR (homologous recombination) D RecBC pathway proteins E ACPL_5485 recD; exodeoxyribonuclease V alpha subunit K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5] E ACPL_7172 recA; recombinase A K03553 recA; recombination protein RecA E ACPL_6534 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA E ACPL_6533 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E ACPL_6535 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] E ACPL_6465 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] E ACPL_7050 Nuclease sbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50 E ACPL_7049 Nuclease sbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11 D RecFOR pathway proteins E ACPL_7172 recA; recombinase A K03553 recA; recombination protein RecA E ACPL_8045 radA; DNA repair protein RadA/Sms K04485 radA; DNA repair protein RadA/Sms E ACPL_119 recF; DNA replication and repair protein recF K03629 recF; DNA replication and repair protein RecF E ACPL_7327 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4] E ACPL_1420 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O) E ACPL_8132 recR; Recombination protein recR K06187 recR; recombination protein RecR E ACPL_6353 recN; DNA repair protein recN K03631 recN; DNA repair protein RecN (Recombination protein N) E ACPL_6534 ruvA; Holliday junction ATP-dependent DNA helicase ruvA K03550 ruvA; holliday junction DNA helicase RuvA E ACPL_6533 ruvB; Holliday junction DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4] E ACPL_6535 ruvC; Holliday junction resolvase K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10] D AddAB pathway proteins D Other HR factor D Archaeal homologous recombinant proteins E ACPL_7050 Nuclease sbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50 E ACPL_7049 Nuclease sbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11 C NHEJ (non-homologous end-joining) D Two-component NHEJ DNA repair complex E ACPL_521 DNA end-binding protein Ku K10979 ku; DNA end-binding protein Ku E ACPL_1154 ligD; DNA ligase (ATP) K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] E ACPL_519 DNA ligase (ATP) K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] E ACPL_520 DNA ligase (ATP) K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] E ACPL_6882 hypothetical protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1] D SHIIR (short-homology-independent illegitimate recombination) E Facilitator F ACPL_124 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F ACPL_6685 gyrA; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2] F ACPL_123 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F ACPL_6686 gyrB; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2] F ACPL_2717 Topoisomerase IB K03168 topA; DNA topoisomerase I [EC:5.6.2.1] F ACPL_490 topA; DNA topoisomerase I K03168 topA; DNA topoisomerase I [EC:5.6.2.1] E Supressor F ACPL_7345 Integration host factor subunit beta K03530 hupB; DNA-binding protein HU-beta D SHDIR (short-homology-dependent illegitimate recombination) E RecET pathway F ACPL_1420 recO; DNA repair protein recO K03584 recO; DNA repair protein RecO (recombination protein O) F ACPL_8132 recR; Recombination protein recR K06187 recR; recombination protein RecR F ACPL_3138 ligA; DNA ligase (NAD+) K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] F ACPL_7390 ligA; NAD-dependent DNA ligase LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2] E Facilitator E Supressor F ACPL_3072 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F ACPL_6571 recQ; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F ACPL_708 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4] F ACPL_1848 uvrA; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A F ACPL_1834 uvrB; excinuclease ABC subunit B K03702 uvrB; excinuclease ABC subunit B B TLS (translesion DNA synthesis) factors C Y-family DNA polymerases D ACPL_1975 dinB; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] D ACPL_6891 dinP; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7] C Other SOS response factors D ACPL_7172 recA; recombinase A K03553 recA; recombination protein RecA D ACPL_2149 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D ACPL_5550 lexA; repressor LexA K01356 lexA; repressor LexA [EC:3.4.21.88] D ACPL_7151 lexA; LexA-like transcriptional repressor K01356 lexA; repressor LexA [EC:3.4.21.88] D ACPL_6353 recN; DNA repair protein recN K03631 recN; DNA repair protein RecN (Recombination protein N) D ACPL_1739 DNA-directed DNA polymerase K14161 imuB; protein ImuB D ACPL_1740 dnaE; DNA polymerase III subunit alpha K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7] D ACPL_1290 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ACPL_5803 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ACPL_8344 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein D ACPL_7171 recX; Regulatory protein recX K03565 recX; regulatory protein B Other factors with a suspected DNA repair function C DNA polymerase C DNA helicases D ACPL_7960 dinG; ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3] D ACPL_7179 lhr; ATP-dependent helicase Lhr and Lhr-like helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4] C Modulation of nucleotide pools D ACPL_133 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_1657 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_1923 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_7674 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_7752 7,8-dihydro-8-oxoguanine triphosphatase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_7959 RNA pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_874 Nudix hydrolase 6 K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_875 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55] D ACPL_7343 NUDIX hydrolase K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69] D ACPL_6345 NUDIX hydrolase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58] D ACPL_7108 dUTP pyrophosphatase K01520 dut; dUTP diphosphatase [EC:3.6.1.23] D ACPL_649 nrdL; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D ACPL_7148 nrdE; ribonucleoside-diphosphate reductase alpha chain K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1] D ACPL_650 nrdM; ribonucleoside-diphosphate reductase beta chain K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1] C Others D ACPL_7211 putative manganese-dependent inorganic pyrophosphatase K06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3] ! #
#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 29, 2025