+F Repair protein KO
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DNA Repair and Recombination Proteins - Anopheles stephensi (Asian malaria mosquito)
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 118508423 activating signal cointegrator 1 complex subunit 3 K18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]
D 118509688 deoxyribodipyrimidine photo-lyase isoform X1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 118504423 single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
E 118506669 N-glycosylase/DNA lyase K03660 OGG1; N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E 118510607 recombination repair protein 1 isoform X1 K10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]
D Long Patch-BER factors
E DNA polymerase delta complex
F 118505959 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
F 118515318 DNA polymerase delta subunit 2-like isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
F 118509849 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
F 118514706 neurofilament heavy polypeptide K03504 POLD3; DNA polymerase delta subunit 3
E DNA polymerase epsilon complex
F 118507826 DNA polymerase epsilon catalytic subunit 1 K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
F 118507828 DNA polymerase epsilon subunit 2 K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
F 118509779 DNA polymerase epsilon subunit 3 K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
F 118511837 DNA polymerase epsilon subunit 4 K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
E 118511037 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 118507297 flap endonuclease 1 K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E 118512576 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D Short Patch-BER factors
E 118504766 DNA repair protein XRCC1 K10803 XRCC1; DNA-repair protein XRCC1
D Other BER factors
E 118506089 probable tyrosyl-DNA phosphodiesterase K10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]
E 118502892 aprataxin-like K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 118504672 aprataxin-like K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 118503302 aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 118504082 uncharacterized protein F21D5.5 K08073 PNKP; bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78]
E 118517458 high mobility group protein DSP1-like K10802 HMGB1; high mobility group protein B1
E 118505793 poly [ADP-ribose] polymerase K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
F 118502574 DNA repair protein complementing XP-C cells homolog K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 118502575 DNA repair protein complementing XP-C cells homolog K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 118504347 DNA repair protein complementing XP-C cells homolog isoform X1 K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 118505452 DNA repair protein complementing XP-C cells homolog K10838 XPC; xeroderma pigmentosum group C-complementing protein
F 118517430 UV excision repair protein RAD23 homolog B-like K10839 RAD23; UV excision repair protein RAD23
E Cul4-DDB2 complex
F 118509359 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 118510145 cullin-4A isoform X1 K10609 CUL4; cullin 4
F 118508296 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
F 118513996 DNA-directed RNA polymerase II subunit RPB1 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 118510016 probable cyclin-dependent serine/threonine-protein kinase DDB_G0292550 K03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]
F 118504901 DNA-directed RNA polymerase II subunit RPB2 K03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]
F 118517684 DNA-directed RNA polymerase II subunit RPB3 K03011 RPB3; DNA-directed RNA polymerase II subunit RPB3
F 118507958 DNA-directed RNA polymerase II subunit Rpb4 K03012 RPB4; DNA-directed RNA polymerase II subunit RPB4
F 118511199 DNA-directed RNA polymerases I, II, and III subunit RPABC1 K03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1
F 118510394 DNA-directed RNA polymerases I, II, and III subunit RPABC2 K03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2
F 118506291 DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
F 118503365 DNA-directed RNA polymerases I, II, and III subunit RPABC3 K03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3
F 118514664 DNA-directed RNA polymerase II subunit RPB9 K03017 RPB9; DNA-directed RNA polymerase II subunit RPB9
F 118505995 DNA-directed RNA polymerases I, II, and III subunit RPABC5 K03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5
F 118512571 DNA-directed RNA polymerase II subunit RPB11 K03008 RPB11; DNA-directed RNA polymerase II subunit RPB11
F 118507341 DNA-directed RNA polymerases I, II, and III subunit RPABC4 K03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4
E Cul4-CSA complex
F 118509359 RING-box protein 1A K03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]
F 118510145 cullin-4A isoform X1 K10609 CUL4; cullin 4
F 118508296 DNA damage-binding protein 1 K10610 DDB1; DNA damage-binding protein 1
E Other TCR factor
F 118507855 transcription elongation factor 1 homolog K25829 ELOF1; transcription elongation factor 1
D TFIIH complex
E 118504059 general transcription and DNA repair factor IIH helicase subunit XPB K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
E 118504338 general transcription and DNA repair factor IIH helicase subunit XPD K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
E 118507750 general transcription factor IIH subunit 1 K03141 TFIIH1; transcription initiation factor TFIIH subunit 1
E 118506071 general transcription factor IIH subunit 2-like K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 118516534 general transcription factor IIH subunit 2-like K03142 TFIIH2; transcription initiation factor TFIIH subunit 2
E 118511682 general transcription factor IIH subunit 3 K03143 TFIIH3; transcription initiation factor TFIIH subunit 3
E 118503822 general transcription factor IIH subunit 4 K03144 TFIIH4; transcription initiation factor TFIIH subunit 4
E 118514154 general transcription factor IIH subunit 5 K10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit
E 118504956 cyclin-dependent kinase 7 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 118512601 cyclin-H K06634 CCNH; cyclin H
E 118508976 CDK-activating kinase assembly factor MAT1 K10842 MNAT1; CDK-activating kinase assembly factor MAT1
D RPA (replication factor A)
E 118506450 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 118509143 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 118511128 replication protein A 14 kDa subunit B-like K10740 RPA3; replication factor A3
D Other NER factors
E 118512103 DNA repair protein complementing XP-A cells homolog K10847 XPA; DNA-repair protein complementing XP-A cells
E 118503470 DNA excision repair protein ERCC-1 K10849 ERCC1; DNA excision repair protein ERCC-1
E 118503249 DNA repair endonuclease XPF K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
E 118509286 DNA repair protein complementing XP-G cells K10846 ERCC5; DNA excision repair protein ERCC-5
E 118512576 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
E 118506161 MMS19 nucleotide excision repair protein homolog K15075 MET18; DNA repair/transcription protein MET18/MMS19
E 118513742 cullin-3 K03869 CUL3; cullin 3
E 118506897 cullin-5 K10612 CUL5; cullin 5
E 118503480 elongin-C K03872 ELOC; elongin-C
E 118508494 elongin-B K03873 ELOB; elongin-B
E 118507905 transcription elongation factor B polypeptide 3 isoform X1 K15076 ELOA; elongin-A
E 118512306 protein lingerer isoform X1 K26545 UBAP2; ubiquitin-associated protein 2
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E 118510965 DNA mismatch repair protein spellchecker 1 K08735 MSH2; DNA mismatch repair protein MSH2
E 118505738 probable DNA mismatch repair protein Msh6 K08737 MSH6; DNA mismatch repair protein MSH6
D MutL homologs
E 118504065 DNA mismatch repair protein Mlh1 K08734 MLH1; DNA mismatch repair protein MLH1
E 118511377 mismatch repair endonuclease PMS2 isoform X1 K10858 PMS2; DNA mismatch repair protein PMS2
D DNA polymerase delta complex
E 118505959 DNA polymerase delta catalytic subunit K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
E 118515318 DNA polymerase delta subunit 2-like isoform X1 K02328 POLD2; DNA polymerase delta subunit 2
E 118509849 DNA polymerase delta subunit 2-like K02328 POLD2; DNA polymerase delta subunit 2
E 118514706 neurofilament heavy polypeptide K03504 POLD3; DNA polymerase delta subunit 3
D RPA (replication factor A)
E 118506450 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 118509143 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 118511128 replication protein A 14 kDa subunit B-like K10740 RPA3; replication factor A3
D RFC (replication factor C)
E 118507123 replication factor C subunit 1 K10754 RFC1; replication factor C subunit 1
E 118505412 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
E 118513239 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
E 118514558 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
E 118511536 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
D Other MMR factors
E 118511037 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
E 118503277 exonuclease 1 K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
E 118517458 high mobility group protein DSP1-like K10802 HMGB1; high mobility group protein B1
E 118512576 DNA ligase 1 isoform X1 K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
E 118511259 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 118507536 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 118504812 nibrin K10867 NBN; nibrin
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
E 118505037 DNA topoisomerase 2-binding protein 1 K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D BRCA1-C complex
E 118511259 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 118507536 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
E 118504812 nibrin K10867 NBN; nibrin
D BRCA complex
E 118514196 breast cancer type 2 susceptibility protein homolog K08775 BRCA2; breast cancer 2 susceptibility protein
E 118504473 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
D RecA family proteins
E 118504473 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 118502636 DNA repair protein RAD51 homolog 3-like isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 118511345 DNA repair protein RAD51 homolog 4 K10871 RAD51L3; RAD51-like protein 3
E 118511558 DNA repair protein XRCC2-like K10879 XRCC2; DNA-repair protein XRCC2
E 118507871 DNA repair protein XRCC3-like K10880 XRCC3; DNA-repair protein XRCC3
D Rad52 family proteins
D Rad54 family proteins
E 118511739 DNA repair and recombination protein RAD54-like K10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]
E 118514220 DNA repair and recombination protein RAD54B-like K10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]
D RecQ family DNA helicases
E 118505895 ATP-dependent DNA helicase Q1-like K10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]
E 118515312 Werner syndrome ATP-dependent helicase-like K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 118502686 Werner syndrome ATP-dependent helicase-like K10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]
E 118504501 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 118510330 uncharacterized protein LOC118510330 isoform X1 K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
E 118504741 uncharacterized protein LOC118504741 isoform X1 K10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]
D Bloom's syndrome complex (BTR)
E 118504501 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 118507568 DNA topoisomerase 3-beta K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 118510567 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 118505897 uncharacterized protein LOC118505897 K10990 RMI1; RecQ-mediated genome instability protein 1
D RPA (replication factor A)
E 118506450 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
E 118509143 replication protein A 32 kDa subunit K10739 RFA2; replication factor A2
E 118511128 replication protein A 14 kDa subunit B-like K10740 RPA3; replication factor A3
D Protein phosphatase 4
E 118502640 serine/threonine-protein phosphatase 4 catalytic subunit K15423 PPP4C; serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]
E 118509805 uncharacterized protein LOC118509805 isoform X1 K15424 PPP4R1; serine/threonine-protein phosphatase 4 regulatory subunit 1
E 118503509 serine/threonine-protein phosphatase 4 regulatory subunit 2 K15425 PPP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2
E 118506777 serine/threonine-protein phosphatase 4 regulatory subunit 3 K17491 SMEK; protein phosphatase 4 regulatory subunit 3
D AP-5 complex
D SMC5-SMC6 complex
E 118506240 structural maintenance of chromosomes protein 5 K22803 SMC5; structural maintenance of chromosomes protein 5
E 118502353 structural maintenance of chromosomes protein 6 isoform X1 K22804 SMC6; structural maintenance of chromosomes protein 6
E 118511566 non-structural maintenance of chromosomes element 1 homolog K22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]
E 118510726 non-structural maintenance of chromosomes element 3 homolog K22823 NSMCE3; non-structural maintenance of chromosomes element 3
E 118511205 EP300-interacting inhibitor of differentiation 3 K22825 NSMCE4; non-structural maintenance of chromosomes element 4
D Other HR factors
E 118508453 crossover junction endonuclease EME1 K10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]
E 118505673 exonuclease 3'-5' domain-containing protein 2 isoform X1 K20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]
E 118515232 crossover junction endonuclease MUS81-like K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 118513579 crossover junction endonuclease MUS81-like K08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]
E 118504866 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 118506690 structure-specific endonuclease subunit SLX1 homolog K15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]
E 118504991 flap endonuclease GEN K15338 GEN1; holliday junction resolvase GEN1/YEN1 [EC:3.1.-.-]
E 118513203 uncharacterized protein LOC118513203 K19026 SPG11; spatacsin
E 118511935 zinc finger FYVE domain-containing protein 26 homolog K19027 ZFYVE26; zinc finger FYVE domain-containing protein 26
E 118507711 mortality factor 4-like protein 1 K11339 MORF4L1; mortality factor 4-like protein 1
E 118510502 deoxynucleoside triphosphate triphosphohydrolase SAMHD1 K22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]
E 118513931 fidgetin-like protein 1 isoform X1 K22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]
E 118503028 uncharacterized protein LOC118503028 K23112 BRAT1; BRCA1-associated ATM activator 1
E 118510367 uncharacterized protein F09G8.5 isoform X1 K23456 CFAP410; cilla- and flagella-associated protein
E 118510081 BRCA2-interacting transcriptional repressor EMSY K25790 EMSY; BRCA2-interacting transcriptional repressor EMSY
E 118515258 uncharacterized protein LOC118515258 K25791 HSF2BP; heat shock factor 2-binding protein
E 118505937 uncharacterized protein LOC118505937 K25791 HSF2BP; heat shock factor 2-binding protein
E 118510498 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
E 118511841 Werner Syndrome-like exonuclease K22807 WRNexo; werner syndrome-like exonuclease [EC:3.1.11.-]
C NHEJ (non-homologous end-joining)
D DNA-PK complex
E 118504995 X-ray repair cross-complementing protein 6 K10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1
E 118509068 X-ray repair cross-complementing protein 5 K10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2
E 118502668 DNA-dependent protein kinase catalytic subunit-like K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D MRX complex
E 118511259 double-strand break repair protein MRE11 K10865 MRE11; double-strand break repair protein MRE11
E 118507536 DNA repair protein RAD50 K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D DNA Ligase 4 complex
E 118502805 DNA ligase 4-like K10777 LIG4; DNA ligase 4 [EC:6.5.1.1]
E 118504183 non-homologous end-joining factor 1 K10980 NHEJ1; non-homologous end-joining factor 1
D X-family DNA polymerases
D Other NHEJ factors
E 118502892 aprataxin-like K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 118504672 aprataxin-like K10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]
E 118503302 aprataxin and PNK-like factor isoform X1 K13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]
E 118515886 protein artemis-like K10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]
C FA (Fanconi anemia) pathway
D FA core complex
E 118511917 uncharacterized protein LOC118511917 K10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]
E 118511416 Fanconi anemia group M protein homolog K10896 FANCM; fanconi anemia group M protein
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
E 118504501 Bloom syndrome protein homolog K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
E 118507568 DNA topoisomerase 3-beta K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 118510567 DNA topoisomerase 3-alpha K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
E 118505897 uncharacterized protein LOC118505897 K10990 RMI1; RecQ-mediated genome instability protein 1
D FANCD2-I complex
E 118505986 Fanconi anemia group D2 protein homolog K10891 FANCD2; fanconi anemia group D2 protein
E 118511602 Fanconi anemia group I protein homolog K10895 FANCI; fanconi anemia group I protein
D Downstream FA components
E 118514196 breast cancer type 2 susceptibility protein homolog K08775 BRCA2; breast cancer 2 susceptibility protein
D Other FA pathway factors
E 118504473 DNA repair protein RAD51 homolog A K04482 RAD51; DNA repair protein RAD51
E 118502636 DNA repair protein RAD51 homolog 3-like isoform X1 K10870 RAD51L2; RAD51-like protein 2
E 118503831 ubiquitin carboxyl-terminal hydrolase 9 K11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]
E 118506129 WD repeat-containing protein 48 homolog K15361 WDR48; WD repeat-containing protein 48
C Other DSBR factors
D Protein phosphatase 6
E 118506855 serine/threonine-protein phosphatase 6 catalytic subunit K15498 PPP6C; serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]
E 118513009 serine/threonine-protein phosphatase 6 regulatory subunit 1 isoform X1 K15501 PPP6R3; serine/threonine-protein phosphatase 6 regulatory subunit 3
E 118502837 uncharacterized protein LOC118502837 isoform X1 K15502 ANKRD28; serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A
D Ubiquitin ligases
E 118507417 probable E3 ubiquitin-protein ligase HERC2 K10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]
D Others
E 118506637 telomerase Cajal body protein 1 homolog K23314 WRAP53; telomerase Cajal body protein 1
E 118510912 gastrulation defective protein 1 homolog K24752 WDR70; WD repeat-containing protein 70
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D 118506470 DNA polymerase eta K03509 POLH; DNA polymerase eta [EC:2.7.7.7]
D 118508490 DNA polymerase iota K03510 POLI; DNA polymerase iota [EC:2.7.7.7]
D 118513086 DNA repair protein REV1 K03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]
C B-family DNA polymerases
D 118502506 DNA polymerase zeta catalytic subunit isoform X1 K02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]
C A-family DNA polymerase
C Rad6 epistasis group
D 118506263 ubiquitin-conjugating enzyme E2-17 kDa isoform X1 K10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]
D 118514244 ubiquitin-conjugating enzyme E2 variant 2 K10704 UBE2V; ubiquitin-conjugating enzyme E2 variant
D 118509354 ubiquitin-conjugating enzyme E2 N K10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]
C Other TLS factors
D 118511037 proliferating cell nuclear antigen K04802 PCNA; proliferating cell nuclear antigen
D 118506902 sprT-like domain-containing protein Spartan K24051 SPRTN; SprT-like domain-contaning protein Spartan
D 118517525 uncharacterized protein LOC118517525 K24051 SPRTN; SprT-like domain-contaning protein Spartan
B Check point factors
C Rad9-Hus1-Rad1 complex
D 118507581 cell cycle checkpoint control protein RAD9A K10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]
D 118504154 checkpoint protein HUS1 K10903 HUS1; HUS1 checkpoint protein
D 118506691 uncharacterized protein LOC118506691 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C HRAD17(Rad24)-RFC complex
D 118512712 cell cycle checkpoint protein RAD17 K06662 HRAD17; cell cycle checkpoint protein
D 118505412 replication factor C subunit 4 K10755 RFC2_4; replication factor C subunit 2/4
D 118513239 replication factor C subunit 2 K10755 RFC2_4; replication factor C subunit 2/4
D 118514558 replication factor C subunit 3 K10756 RFC3_5; replication factor C subunit 3/5
D 118511536 replication factor C subunit 5 K10756 RFC3_5; replication factor C subunit 3/5
C Rad17-Mec3-Ddc1 complex
D 118506691 uncharacterized protein LOC118506691 K02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]
C FPC (fork protection complex)
D 118508128 protein timeless homolog isoform X1 K10997 TIMELESS; replication fork protection complex subunit TIMELESS/Tof1/Swi1
D 118509270 protein TIPIN homolog K10998 TIPIN; replication fork protection complex subunit TIPIN/Csm3/Swi3
D 118508295 claspin-like K25773 CLSPN; claspin
C Triple T complex
D 118502951 TELO2-interacting protein 1 homolog K20403 TTI1; TELO2-interacting protein 1
C BAG6-UBL4A-GET4 complex
D 118513054 large proline-rich protein BAG6 isoform X1 K23390 BAG6; large proline-rich protein BAG6
D 118506956 ubiquitin-like protein 4A-B K23388 UBL4; ubiquitin-like protein 4
D 118505402 Golgi to ER traffic protein 4 homolog K23387 GET4; golgi to ER traffic protein 4
C Other check point factors
D 118517699 serine/threonine-protein kinase ATR K06640 ATR; serine/threonine-protein kinase ATR [EC:2.7.11.1]
D 118511628 serine/threonine-protein kinase ATM K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D 118513733 serine/threonine-protein kinase grp K02216 CHEK1; serine/threonine-protein kinase CHEK1 [EC:2.7.11.1]
D 118509132 ovarian-specific serine/threonine-protein kinase Lok-like K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 118513441 ovarian-specific serine/threonine-protein kinase Lok isoform X1 K06641 CHEK2; serine/threonine-protein kinase CHEK2 [EC:2.7.11.1]
D 118502694 uncharacterized protein LOC118502694 isoform X1 K05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]
D 118508867 14-3-3 protein zeta isoform X1 K16197 YWHAB_Q_Z; 14-3-3 protein beta/theta/zeta
D 118517541 14-3-3 protein epsilon K06630 YWHAE; 14-3-3 protein epsilon
D 118510785 protein sickie isoform X1 K19483 NAV2; neuron navigator 2 [EC:5.6.2.4]
D 118513986 wee1-like protein kinase K06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]
D 118506664 uncharacterized protein LOC118506664 K02633 PER2; period circadian protein 2
D 118509409 mediator of DNA damage checkpoint protein 1-like isoform X1 K20780 MDC1; mediator of DNA damage checkpoint protein 1
D 118506900 plastin-1 isoform X1 K17336 PLS3; plastin-3
D 118510355 protein downstream neighbor of son homolog K22422 DONSON; protein downstream neighbor of Son
D 118508588 vacuolar protein sorting-associated protein 4B K12196 VPS4; vacuolar protein-sorting-associated protein 4
D 118505578 abscission/NoCut checkpoint regulator K24778 ZFYVE19; abscission/NoCut checkpoint regulator
D 118512333 replication stress response regulator SDE2 K25059 SDE2; replication stress response regulator SDE2
B Other factors with a suspected DNA repair function
C DNA polymerases
D 118512159 DNA polymerase theta K02349 POLQ; DNA polymerase theta [EC:2.7.7.7]
D 118504810 myb-binding protein 1A-like K02331 POL5; DNA polymerase phi [EC:2.7.7.7]
C Nucleases
D 118514262 LOW QUALITY PROTEIN: uncharacterized protein LOC118514262 K10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]
D 118517643 DNA cross-link repair 1A protein-like K15340 DCLRE1A; DNA cross-link repair 1A protein
D 118503538 ankyrin repeat and LEM domain-containing protein 1 K21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1
C Helicases
D 118503060 helicase POLQ-like K19178 HELQ; POLQ-like helicase [EC:5.6.2.4]
C PSO4 complex
D 118510232 pre-mRNA-processing factor 19 K10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]
D 118504482 cell division cycle 5-like protein K12860 CDC5L; pre-mRNA-splicing factor CDC5/CEF1
D 118508455 pre-mRNA-splicing factor SPF27 K12861 BCAS2; pre-mRNA-splicing factor SPF27
D 118512795 pleiotropic regulator 1 K12862 PLRG1; pleiotropic regulator 1
C Modulation of nucleotide pools
D 118506935 8-oxo-dGDP phosphatase NUDT18 K17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D 118511127 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D 118511057 ribonucleoside-diphosphate reductase large subunit K10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]
D 118513289 ribonucleoside-diphosphate reductase subunit M2 isoform X1 K10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D 118509688 deoxyribodipyrimidine photo-lyase isoform X1 K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E 118504423 single-strand selective monofunctional uracil DNA glycosylase K10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]
D AP endonucleases
D RecJ
D DNA ligase
D DNA polymerase I
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
E TRCF (transcription-repair coupling factor)
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
D DNA polymerase III holoenzyme
D DNA ligase
D Other MMR factors
E 118508294 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
D RecFOR pathway proteins
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
E Supressor
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
E Facilitator
E Supressor
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C Other SOS response factors
D 118508294 single-stranded DNA-binding protein, mitochondrial K03111 ssb; single-strand DNA-binding protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
C Modulation of nucleotide pools
D 118511127 deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
C Others
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#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024