+C Two-component system KO
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Two-Component System - Azoarcus olearius BH72
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C azo0165 phoR; phosphate regulon sensor protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C azo0164 phoB; phosphate regulon transcriptional regulatory protein K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
C azo2411 yycF; transcriptional regulatory protein K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
C azo1708 envZ1; probable osmolarity sensor protein K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C azo1709 ompR1; response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C azo0703 creC; catabolite repression sensor kinase for PhoB K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
C azo0704 creB; two-component system regulatory protein K07663 creB; two-component system, OmpR family, catabolic regulation response regulator CreB
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
C azo2945 copS; two component sensor kinase K07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]
C azo2946 copR; two component response regulator K07665 cusR; two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C azo2799 kdpD1; probable two component sensor protein K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C azo3094 kdpD2; probable sensor for high-affinity potassium transport system K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C azo2800 kdpE; two component system transcriptional regulatory protein K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
C azo3093 two component system transcriptional regulatory protein K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C azo3673 qseC2; two-component system histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C azo0263 probable two-component system histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C azo2745 ompR2; probable DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C azo0457 ragA; two-component response regulator K02483 K02483; two-component system, OmpR family, response regulator
C azo0975 basR; probable two-component response regulatory protein K02483 K02483; two-component system, OmpR family, response regulator
C azo0054 rstA; probable two-component response regulator K02483 K02483; two-component system, OmpR family, response regulator
C azo3615 ompR3; DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C azo0693 virG; probable DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C azo0979 tctD; probable transcriptional regulatory protein K02483 K02483; two-component system, OmpR family, response regulator
C azo3672 qseB2; DNA-binding response regulator K02483 K02483; two-component system, OmpR family, response regulator
C azo0264 qseB1; transcriptional regulatory protein K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
C azo0648 putative DNA-binding response regulator, LuxR family K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
C azo2979 elmS; putative two-component sensor histidine kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
C azo2971 putative two-component sensor histidine kinase K07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
C azo2980 gacA; probable transcriptional regulator, LuxR family K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
C azo2970 uvrY; probable two-component response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
C azo0569 vsrD1; DNA-binding response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
C azo1503 putative two-component response regulator K07689 uvrY; two-component system, NarL family, invasion response regulator UvrY
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
C azo0990 algZ; putative alginate biosynthesis protein AlgZ/FimS K08082 algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]
C azo0991 algR; probable alginate biosynthesis regulatory protein AlgR K08083 algR; two-component system, LytTR family, response regulator AlgR
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C azo0736 ntrB; nitrogen regulation protein NR(II) K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C azo0735 ntrC; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
C azo3983 ntrY; probable nitrogen regulation protein K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C azo3982 ntrX; probable nitrogen assimilation regulatory protein K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
C azo1842 lapR; transcriptional regulatory protein K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
C azo3357 pilS; two component system sensor protein K02668 pilS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]
C azo3356 pilR; two component system response regulator K02667 pilR; two-component system, NtrC family, response regulator PilR
B GlrK-GlrR (amino sugar metabolism)
C azo2768 yfhK; putative two-component system sensor kinase K07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]
C azo2770 yfhA; putative two component transcriptional regulator K07715 glrR; two-component system, NtrC family, response regulator GlrR
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C azo0448 dctB1; sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C azo1915 dctB2; sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C azo0447 dctD1; transcriptional regulatory protein K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C azo1914 dctD2; transcriptional regulatory protein K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
C azo3810 hoxJ; hydrogen uptake histidine-kinase K19661 hupT; two-component system, NtrC family, sensor histidine kinase HupT/HoxJ [EC:2.7.13.3]
C azo3805 hoxA; hydrogenase transcriptional regulatory protein K19641 hupR; two-component system, NtrC family, response regulator HupR/HoxA
B Unclassified
C azo0072 putative sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C azo3492 putative sensor histidine kinase K02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]
C azo3191 atoC; probable acetoacetate metabolism regulatory protein K02481 flgR; two-component system, NtrC family, response regulator
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ACheA family
B CheA-CheYBV (chemotaxis)
C azo0408 cheA1; putative chemotaxis protein histidine kinase K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C azo1462 cheA3; chemotaxis protein cheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C azo1451 cheA2; chemotaxis protein cheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C azo1460 cheY3; chemotaxis response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C azo0411 cheY1; probable chemotaxis response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C azo1450 cheY2; putative chemotaxis response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C azo2058 ccdB; probable response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C azo3946 putative two component transcriptional regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C azo0402 cheB1; probable protein glutamate-methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C azo1456 cheB2; protein glutamate-methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C azo1459 cheV2; probable chemotaxis protein CheV-like K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
C azo1458 cheV1; probable chemotaxis protein CheV-like K03415 cheV; two-component system, chemotaxis family, chemotaxis protein CheV
B ChpA-ChpB/PilGH (chemosensory)
C azo3457 pilL; putative pilus biogenese protein K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
C azo3453 pilG; pilus protein K02657 pilG; twitching motility two-component system response regulator PilG
C azo3454 pilH; pilus protein K02658 pilH; twitching motility two-component system response regulator PilH
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
C azo1491 divK; probable polar differentiation response regulator K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
C azo0918 dctS; two-component sensor kinase K11711 dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3]
C azo0917 two-component response regulator K11712 dctR; two-component system, LuxR family, response regulator DctR
B TtrS-TtrR (tetrathionate respiration)
C azo2672 conserved hypothetical sensor histidine kinase K13040 ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]
B FixL-FixJ (nitrogen fixation)
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
C azo2715 fleS; putative sensory box sensor histidine kinase K10942 flrB; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]
C azo2714 fleR; sigma-54 dependent response regulator K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
C azo3686 rpfG; probable response regulator K13815 rpfG; two-component system, response regulator RpfG
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C azo3438 vsrB; putative virulence regulator protein K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
B NasS-NasT
B Unclassified
C azo2482 putative hybrid sensor and regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
C azo2575 gacS; putative two-component hybrid sensor and regulator K11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023