+C Two-component system KO
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Two-Component System - Azospirillum sp. TSH100
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C E6C72_04555 PAS domain-containing protein K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C E6C72_04580 phoB; phosphate regulon transcriptional regulatory protein PhoB K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
C E6C72_01225 response regulator K07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
C E6C72_10040 HAMP domain-containing protein K07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]
C E6C72_10045 response regulator K07659 ompR; two-component system, OmpR family, phosphate regulon response regulator OmpR
B RstB-RstA
B CpxA-CpxR (envelope stress response)
C E6C72_14850 HAMP domain-containing histidine kinase K07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]
C E6C72_14855 response regulator transcription factor K07662 cpxR; two-component system, OmpR family, response regulator CpxR
C E6C72_14875 response regulator K07662 cpxR; two-component system, OmpR family, response regulator CpxR
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
C E6C72_15775 HAMP domain-containing histidine kinase K07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C E6C72_17280 response regulator transcription factor K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
C E6C72_26110 response regulator K07772 torR; two-component system, OmpR family, torCAD operon response regulator TorR
C E6C72_29410 response regulator K07772 torR; two-component system, OmpR family, torCAD operon response regulator TorR
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
C E6C72_13280 sensor histidine kinase K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C E6C72_20535 extracellular solute-binding protein K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C E6C72_24375 extracellular solute-binding protein K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
C E6C72_13275 response regulator transcription factor K07774 tctD; two-component system, OmpR family, response regulator TctD
C E6C72_20540 response regulator transcription factor K07774 tctD; two-component system, OmpR family, response regulator TctD
C E6C72_24380 response regulator transcription factor K07774 tctD; two-component system, OmpR family, response regulator TctD
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
C E6C72_04740 HAMP domain-containing protein K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
C E6C72_14260 HAMP domain-containing histidine kinase K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
C E6C72_04735 response regulator transcription factor K14981 chvI; two-component system, OmpR family, response regulator ChvI
C E6C72_14265 response regulator transcription factor K14981 chvI; two-component system, OmpR family, response regulator ChvI
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
C E6C72_21650 HAMP domain-containing protein K18143 adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]
C E6C72_21655 response regulator transcription factor K18144 adeR; two-component system, OmpR family, response regulator AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C E6C72_05360 response regulator K02483 K02483; two-component system, OmpR family, response regulator
C E6C72_05635 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C E6C72_06310 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C E6C72_08885 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C E6C72_11445 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C E6C72_13515 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C E6C72_13715 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C E6C72_15780 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
C E6C72_18395 response regulator transcription factor K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
C E6C72_00915 response regulator transcription factor K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
C E6C72_10035 response regulator transcription factor K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
C E6C72_20255 response regulator transcription factor K07684 narL; two-component system, NarL family, nitrate/nitrite response regulator NarL
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B BtsS-BtsR (pyruvate reutilization)
C E6C72_28475 sensor histidine kinase K27882 btsS; two-component system, LytTR family, low-concentration pyruvate sensor kinase [EC:2.7.13.3]
C E6C72_28470 yehT; two-component system response regulator BtsR K27883 btsR; two-component system, LytTR family, low-concentration pyruvate response regulator
B PyrS-PyrR (pyruvate reutilization)
B Unclassified
C E6C72_14935 sensor histidine kinase K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C E6C72_14940 yehT; two-component system response regulator BtsR K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C E6C72_10715 PAS domain-containing protein K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C E6C72_10710 ntrC; nitrogen regulation protein NR(I) K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
C E6C72_10705 PAS domain-containing sensor histidine kinase K13598 ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]
C E6C72_10700 sigma-54-dependent Fis family transcriptional regulator K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
B AtoS-AtoC (cPHB biosynthesis)
C E6C72_18455 atoS; two-component system sensor histidine kinase AtoS K07710 atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]
C E6C72_18450 atoC; acetoacetate metabolism transcriptional regulator AtoC K07714 atoC; two-component system, NtrC family, response regulator AtoC
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
C E6C72_17780 sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C E6C72_29235 sensor histidine kinase K10125 dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]
C E6C72_17785 sigma-54-dependent Fis family transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
C E6C72_29230 sigma-54-dependent Fis family transcriptional regulator K10126 dctD; two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
C E6C72_21040 PAS domain-containing protein K19661 hupT; two-component system, NtrC family, sensor histidine kinase HupT/HoxJ [EC:2.7.13.3]
C E6C72_20995 sigma-54-dependent Fis family transcriptional regulator K19641 hupR; two-component system, NtrC family, response regulator HupR/HoxA
B Unclassified
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ACheA family
B CheA-CheYBV (chemotaxis)
C E6C72_01695 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C E6C72_11510 chemotaxis protein CheW K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C E6C72_13355 response regulator K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C E6C72_26730 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C E6C72_27395 hybrid sensor histidine kinase/response regulator K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C E6C72_01320 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C E6C72_01690 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C E6C72_04080 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C E6C72_08855 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C E6C72_12795 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C E6C72_13420 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C E6C72_26725 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C E6C72_27385 response regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C E6C72_01720 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C E6C72_11515 response regulator K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C E6C72_11520 cheB; chemotaxis-specific protein-glutamate methyltransferase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C E6C72_13350 response regulator K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C E6C72_19765 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C E6C72_26710 cheB; chemotaxis-specific protein-glutamate methyltransferase CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C E6C72_27380 chemotaxis response regulator protein-glutamate methylesterase K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C E6C72_19220 chemotaxis protein K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
C E6C72_20205 PAS domain S-box protein K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
C E6C72_20260 response regulator K13924 cheBR; two-component system, chemotaxis family, CheB/CheR fusion protein [EC:2.1.1.80 3.1.1.61]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
C E6C72_17670 GAF domain-containing protein K11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]
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ACell cycle family
B PleC-PleD (cell fate control)
C E6C72_07465 two-component sensor histidine kinase K07716 pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]
C E6C72_12410 PleD family two-component system response regulator K02488 pleD; two-component system, cell cycle response regulator [EC:2.7.7.65]
C E6C72_12415 response regulator K11443 divK; two-component system, cell cycle response regulator DivK
C E6C72_17310 response regulator K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
C E6C72_09230 response regulator K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C E6C72_12080 response regulator K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C E6C72_27355 response regulator transcription factor K13584 ctrA; two-component system, cell cycle response regulator CtrA
C E6C72_28315 response regulator transcription factor K13584 ctrA; two-component system, cell cycle response regulator CtrA
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
C E6C72_29785 sigma-54-dependent Fis family transcriptional regulator K10912 luxO; two-component system, repressor protein LuxO
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
C E6C72_08210 PAS domain S-box protein K11711 dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3]
C E6C72_08205 response regulator transcription factor K11712 dctR; two-component system, LuxR family, response regulator DctR
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
C E6C72_18070 histidine kinase K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
C E6C72_22065 PAS domain S-box protein K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
C E6C72_06080 response regulator K14987 fixJ; two-component system, LuxR family, response regulator FixJ
C E6C72_22070 response regulator transcription factor K14987 fixJ; two-component system, LuxR family, response regulator FixJ
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
C E6C72_13460 sigma-54-dependent Fis family transcriptional regulator K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
C E6C72_23850 sensor histidine kinase K17060 aauS; two-component system, sensor histidine kinase AauS [EC:2.7.13.3]
C E6C72_23845 sigma-54-dependent Fis family transcriptional regulator K17061 aauR; two-component system, response regulator AauR
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
C E6C72_27685 response regulator K13815 rpfG; two-component system, response regulator RpfG
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C E6C72_26785 ActS/PrrB/RegB family redox-sensitive histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C E6C72_28190 HAMP domain-containing histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C E6C72_26790 ActR/PrrA/RegA family redox response regulator transcription factor K15012 regA; two-component system, response regulator RegA
C E6C72_28195 response regulator transcription factor K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C E6C72_08945 response regulator K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
C E6C72_09525 response regulator K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
C E6C72_09930 PAS domain S-box protein K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
C E6C72_14570 response regulator K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
C E6C72_27780 HAMP domain-containing protein K20975 K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]
B PdtaS-PdtaR
C E6C72_10610 response regulator K22010 pdtaR; two-component system, response regulator PdtaR
C E6C72_29550 response regulator K22010 pdtaR; two-component system, response regulator PdtaR
B NasS-NasT
B Unclassified
C E6C72_03250 histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS
C E6C72_03255 histidine kinase K20971 ladS; two-component system, sensor histidine kinase LadS
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: October 8, 2024