+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Bacillus sp. SDLI1

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS E AUL54_18785 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_02040 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_03375 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_02045 acyltransferase K15328 pksD; bacillaene synthase trans-acting acyltransferase E AUL54_02015 non-ribosomal peptide synthetase K13611 pksJ; bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksJ/BaeJ E AUL54_02010 polyketide synthase K13612 pksL; bacillaene polyketide synthase PksL/BaeL E AUL54_02005 polyketide synthase K13613 pksM; bacillaene polyketide synthase PksM/BaeM E AUL54_02000 non-ribosomal peptide synthetase K13614 pksN; bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksN/BaeN E AUL54_01995 polyketide synthase K13615 pksR; bacillaene polyketide synthase PksR/BaeR D Chivosazol hybrid PKS-NRPS E AUL54_18785 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_02040 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_03375 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS E AUL54_18785 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_02040 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_03375 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_03370 polyketide synthase K25842 mlnB; macrolactin polyketide synthase MlnB E AUL54_03365 polyketide synthase K25843 mlnC; macrolactin polyketide synthase MlnC E AUL54_03360 polyketide synthase K25844 mlnD; macrolactin polyketide synthase MlnD E AUL54_03355 polyketide synthase K25845 mlnE; macrolactin polyketide synthase MlnE E AUL54_03350 polyketide synthase K25846 mlnF; macrolactin polyketide synthase MlnF E AUL54_03345 polyketide synthase K25847 mlnG; macrolactin polyketide synthase MlnG E AUL54_03340 MlnH K25848 mlnH; macrolactin polyketide synthase MlnH D Difficidin PKS E AUL54_18785 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_02040 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_03375 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AUL54_18810 polyketide synthase K25849 dfnD; difficidin synthase DfnD E AUL54_18815 polyketide synthase K25850 dfnE; difficidin synthase DfnE E AUL54_18820 polyketide synthase K25851 dfnF; difficidin synthase DfnF E AUL54_18825 polyketide synthase K25852 dfnG; difficidin synthase DfnG E AUL54_18830 polyketide synthase K25853 dfnH; difficidin synthase DfnH E AUL54_18835 polyketide synthase K25854 dfnI; difficidin synthase DfnI E AUL54_18840 DfnJ K25855 dfnJ; difficidin synthase DfnJ D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:AN1034.2] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:AN1036.2] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS C C7-C14 cyclized polyketide type D Octaketide PKS D Nonaketide PKS D Decaketide PKS B Type III PKS C Plant type C Fungal type C Bacterial type D AUL54_00290 chalcone synthase K16167 bpsA; alkylresorcinol/alkylpyrone synthase D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:AN2545.2] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase D AUL54_09000 non-ribosomal peptide synthetase K15654 srfAA; surfactin/lichenysin synthetase A D AUL54_08995 non-ribosomal peptide synthetase K15655 srfAB; surfactin/lichenysin synthetase B D AUL54_08990 non-ribosomal peptide synthetase K15656 srfAC; surfactin/lichenysin synthetase C C Iturin family lipopeptide synthetase D AUL54_01495 non-ribosomal peptide synthetase K15661 ituA; iturin family lipopeptide synthetase A D AUL54_01500 non-ribosomal peptide synthetase K15662 ituB; iturin family lipopeptide synthetase B D AUL54_01505 non-ribosomal peptide synthetase K15663 ituC; iturin family lipopeptide synthetase C C Fengycin family lipopeptide synthetase D AUL54_01355 non-ribosomal peptide synthetase K15664 ppsA; plipastatin/fengycin lipopeptide synthetase A D AUL54_01360 non-ribosomal peptide synthetase K15665 ppsB; plipastatin/fengycin lipopeptide synthetase B D AUL54_01365 non-ribosomal peptide synthetase K15666 ppsC; plipastatin/fengycin lipopeptide synthetase C D AUL54_01370 non-ribosomal peptide synthetase K15667 ppsD; plipastatin/fengycin lipopeptide synthetase D D AUL54_01375 non-ribosomal peptide synthetase K15668 ppsE; plipastatin/fengycin lipopeptide synthetase E C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D AUL54_15205 protein mbtH K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D AUL54_15195 isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D AUL54_15190 entE; 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Bacillibactin synthetase D AUL54_15195 isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D AUL54_15190 entE; 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D AUL54_15200 non-ribosomal peptide synthetase K04780 dhbF; glyine---[glycyl-carrier protein] ligase [EC:6.2.1.66] C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase D AUL54_15195 isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D AUL54_15190 entE; 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Myxochelin synthetase D AUL54_15190 entE; 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D AUL54_15195 isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase D AUL54_15195 isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D AUL54_15190 entE; 2,3-dihydroxybenzoate-AMP ligase K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase C AUL54_01990 cytochrome K15468 pksS; cytochrome P450 family 107 subfamily K polypeptide 1 B Methylase C AUL54_00295 hypothetical protein K16168 bpsB; methyltransferase B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins C AUL54_02050 poly(3-hydroxyalkanoate) synthetase K15327 pksC; polyketide biosynthesis malonyl-CoA-[acyl-carrier-protein] transacylase C AUL54_02035 poly(3-hydroxyalkanoate) depolymerase K15337 acpK; polyketide biosynthesis acyl carrier protein C AUL54_18850 3-hydroxy-3-methylglutaryl-ACP synthase K15311 pksG; 3-carboxymethyl-3-hydroxy-acyl-[acp] synthase [EC:2.3.3.22] C AUL54_02030 3-hydroxy-3-methylglutaryl-ACP synthase K15311 pksG; 3-carboxymethyl-3-hydroxy-acyl-[acp] synthase [EC:2.3.3.22] C AUL54_02025 enoyl-CoA hydratase K15312 pksH; 3-carboxymethyl-3-hydroxy-acyl-[acp] dehydratase [EC:4.2.1.181] C AUL54_18855 enoyl-CoA hydratase K15313 pksI; 4-carboxy-3-alkylbut-2-enoyl-[acp] decarboxylase [EC:4.1.1.125] C AUL54_02020 enoyl-CoA hydratase K15313 pksI; 4-carboxy-3-alkylbut-2-enoyl-[acp] decarboxylase [EC:4.1.1.125] B Others # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase C AUL54_08985 thioesterase K15657 srfATE; external thioesterase TEII B Oxygenase B Glycosyltransferase B Aminotransferase B Others C AUL54_07445 hypothetical protein K01779 racD; aspartate racemase [EC:5.1.1.13] ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: February 19, 2024