+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Bacillus velezensis UCMB5033
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C RBAU_1504 lspA; signal peptidase II K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
B Family A25: gpr protease family
C RBAU_2518 gpr; spore endopeptidase K06012 gpr; spore protease [EC:3.4.24.78]
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
B Family A36
C RBAU_1490 spoIIGA; protease processing pro-sigma-E K06383 spoIIGA; stage II sporulation protein GA (sporulation sigma-E factor processing peptidase) [EC:3.4.23.-]
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
C RBAU_0268 pcp; pyrrolidone-carboxylate peptidase K01304 pcp; pyroglutamyl-peptidase [EC:3.4.19.3]
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C RBAU_0653 guaA; GMP synthetase K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C RBAU_0554 Glutamine amidotransferase K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
B Family C40
C RBAU_0926 lytF; gamma-D-glutamate-meso-diaminopimelate muropeptidase (major autolysin) K19223 lytF; peptidoglycan DL-endopeptidase LytF [EC:3.4.-.-]
C RBAU_0931 conserved exported protein of unknown function K19224 lytE; peptidoglycan DL-endopeptidase LytE [EC:3.4.-.-]
C RBAU_1886 cwlS; peptidoglycan hydrolase (cell wall-binding d,l-endopeptidase) K19220 cwlS; peptidoglycan DL-endopeptidase CwlS [EC:3.4.-.-]
C RBAU_3339 cwlO; secreted cell wall DL-endopeptidase K21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]
C RBAU_1261 ykfC; gamma-D-glutamyl-L-diaminoacid endopeptidase K20742 ykfC; gamma-D-glutamyl-L-lysine dipeptidyl-peptidase [EC:3.4.14.13]
B Family C44
C RBAU_0669 purF; glutamine phosphoribosylpyrophosphate amidotransferase K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C RBAU_1833 gltA; glutamate synthase (large subunit) K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C RBAU_0196 glmS; L-glutamine-D-fructose-6-phosphate amidotransferase K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C RBAU_2891 asnB; asparagine synthetase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C RBAU_1055 asnO; asparagine synthetase K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C RBAU_2953 pfpI; Intracellular protease 1 K05520 yhbO; deglycase [EC:3.5.1.124]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
C RBAU_3724 yxeI; penicillin V acylase K24041 yxeI; penicillin V amidase [EC:3.5.1.11]
B Family C60
C RBAU_0909 srtA; sortase A K07284 srtA; sortase A [EC:3.4.22.70]
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
C RBAU_2256 ypbD; putative membrane protease K07052 K07052; CAAX protease family protein
C RBAU_0601 ydiL; putative membrane protease K07052 K07052; CAAX protease family protein
C RBAU_3911 yyaK; putative integral inner membrane protein K07052 K07052; CAAX protease family protein
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AMetallo peptidases
B Family M1
B Family M2
B Family M3
C RBAU_1115 pepF; oligoendopeptidase F K08602 pepF; oligoendopeptidase F [EC:3.4.24.-]
B Family M4: thermolysin family
C RBAU_1436 nprE; extracellular neutral metalloprotease K01400 nprE; bacillolysin [EC:3.4.24.28]
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
B Family M14: carboxypeptidase A family
C RBAU_2451 yqgT; putative gamma-D-glutamyl-L-diamino acid endopeptidase K01308 yqgT; g-D-glutamyl-meso-diaminopimelate peptidase [EC:3.4.19.11]
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
C RBAU_1911 yodJ; D-alanyl-D-alanine carboxypeptidase lipoprotein K07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]
C RBAU_0279 cwlK; Peptidoglycan L-alanyl-D-glutamate endopeptidase K17733 cwlK; peptidoglycan LD-endopeptidase CwlK [EC:3.4.-.-]
B Family M16: pitrilysin family
B Family M17: leucyl aminopeptidase family
C RBAU_3041 pepA; leucyl aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
B Family M18
B Family M19: membrane dipeptidase family
B Family M20
C RBAU_2846 ytjP; putative dipeptidase K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C RBAU_2357 yqjE; putative deacylase K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
C RBAU_3738 pepT; peptidase T (tripeptidase) K01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]
C RBAU_0993 yhaA; putative amidohydrolase K01436 yhaA; amidohydrolase [EC:3.5.1.-]
C RBAU_0368 yxeP; putative amidohydrolase K21613 scmP; N-acetylcysteine deacetylase [EC:3.5.1.-]
C RBAU_0297 amhX; amidohydrolase K14665 amhX; amidohydrolase [EC:3.5.1.-]
C RBAU_1379 dapL; N-acetyl-diaminopimelate deacetylase K05823 dapL; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]
C RBAU_3088 pucF; allantoate amidohydrolase K02083 allC; allantoate deiminase [EC:3.5.3.9]
B Family M23
C RBAU_3074 lytH; sporulation-specific L-Ala-D-Glu endopeptidase K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-]
B Family M24
C RBAU_0145 mapA; methionine aminopeptidase K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C RBAU_0765 mapB; methionine aminopeptidase B K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C RBAU_2415 yqhT; putative aminopeptidase K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
C RBAU_3260 ywaD; Aminopeptidase YwaD K19701 ywaD; aminopeptidase YwaD [EC:3.4.11.6 3.4.11.10]
B Family M29: aminopeptidase T family
C RBAU_1402 ampS; aminopeptidase K19689 ampS; aminopeptidase [EC:3.4.11.-]
B Family M32: carboxypeptidase Taq family
C RBAU_2168 ypwA; metal-dependent carboxypeptidase K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C RBAU_0074 ftsH; cell-division protein and general stress protein (class III heat-shock) K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
C RBAU_1004 yhfE; putative endoglucanase K01269 yhfE; aminopeptidase [EC:3.4.11.-]
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C RBAU_1304 htpX; membrane protease K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C RBAU_2640 spoIVFB; membrane metalloprotease K06402 spoIVFB; stage IV sporulation protein FB [EC:3.4.24.-]
C RBAU_1617 rseP; inner membrane zinc metalloprotease required for the extracytoplasmic stress response mediated by sigma(E) (YaeL) K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
C RBAU_1254 dppA; D-alanyl-aminopeptidase K16203 dppA1; D-amino peptidase [EC:3.4.11.-]
B Family M56
B Family M67
B Family M72
B Family M73
C RBAU_2430 tasA; major biofilm matrix component K06336 tasA; spore coat-associated protein N
B Family M74
B Family M80
B Family M82
C RBAU_2249 prsW; protease required for RsiW anti-sigma(W) degradation K24131 prsW; protease PrsW [EC:3.4.-.-]
B Family M85
B Family M88
B Family M90
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C RBAU_0837 mpr; extracellular glutamyl endopeptidase K01318 sspA; glutamyl endopeptidase [EC:3.4.21.19]
C RBAU_3142 htrB; HtrA-like serine protease K04771 degP; serine protease Do [EC:3.4.21.107]
C RBAU_1252 htrA; membrane bound serine protease Do, quality control protease (heat-shock protein) K04771 degP; serine protease Do [EC:3.4.21.107]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C RBAU_1012 aprE; serine alkaline protease (subtilisin E) K01342 aprE; subtilisin [EC:3.4.21.62]
C RBAU_1489 bpr; bacillopeptidase F K13276 bpr; bacillopeptidase F [EC:3.4.21.-]
C RBAU_1283 isp; intracellular serine protease K13275 isp; major intracellular serine protease [EC:3.4.21.-]
C RBAU_3665 vpr; extracellular serine protease K14647 vpr; minor extracellular serine protease Vpr [EC:3.4.21.-]
C RBAU_3695 epr; extracellular serine protease K13277 epr; minor extracellular protease Epr [EC:3.4.21.-]
C RBAU_1689 aprX; alkaline serine protease K17734 aprX; serine protease AprX [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C RBAU_0012 dacA; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C RBAU_2272 dacB; D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5*) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C RBAU_2298 dacF; D-alanyl-D-alanine carboxypeptidase (penicilin binding protein) K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
C RBAU_0186 amiE; amidase hydrolyzing N-acetylmuramyl-L-Ala bond of MurNAc peptides K21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]
B Family S13: D-Ala-D-Ala peptidase C family
C RBAU_1820 dacC; D-alanyl-D-alanine carboxypeptidase K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C RBAU_3321 clpP; ATP-dependent Clp protease proteolytic subunit K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C RBAU_2664 lonA; class III heat-shock ATP-dependent LonA protease K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
C RBAU_2665 lonB; LonB ATP-dependent protease K04076 lonB; ATP-dependent Lon protease [EC:3.4.21.53]
C RBAU_1468 ylbL; putative degradative enzyme K07177 K07177; Lon-like protease
B Family S21: assemblin family
B Family S24: LexA family
C RBAU_1742 lexA; transcriptional repressor of the SOS regulon K01356 lexA; repressor LexA [EC:3.4.21.88]
B Family S26: signal peptidase I family
C RBAU_1398 sipT; type I signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89]
C RBAU_2283 sipS; type I signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89]
C RBAU_1033 sipV; type I signal peptidase K03100 lepB; signal peptidase I [EC:3.4.21.89]
C RBAU_2431 sipW; type I signal peptidase K13280 SEC11; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
C RBAU_0841 yfhM; putative epoxide hydrolase-like protein K22369 EPHX4; epoxide hydrolase 4 [EC:3.3.-.-]
B Family S41: C-terminal processing peptidase family
C RBAU_1908 ctpA; carboxy-terminal processing protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C RBAU_3377 ctpB; PDZ-containing carboxyl-terminal protease processing protease K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
B Family S45
B Family S49: protease IV family
C RBAU_2785 sppA; signal peptide peptidase K04773 sppA; protease IV [EC:3.4.21.-]
B Family S50
B Family S51
C RBAU_0861 ygaJ; putative peptidase K05995 pepE; dipeptidase E [EC:3.4.13.21]
B Family S53
B Family S54: Rhomboid family
B Family S55: SpoIVB peptidase family
C RBAU_2392 spoIVB; regulatory membrane-associated serine protease (SpoIVB peptidase) K06399 spoIVB; stage IV sporulation protein B [EC:3.4.21.116]
B Family S62
B Family S66
C RBAU_1259 ldcA; muropeptide L,D-carboxypeptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
C RBAU_1861 yocD; putative carboxypeptidase K01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C RBAU_1574 clpQ; two-component ATP-dependent protease (N-terminal serine protease) K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
B Family T3: gamma-glutamyltransferase family
C RBAU_1826 ggt; membrane bound gamma-glutamyltranspeptidase K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C RBAU_3467 ywrD; putative enzyme K22602 hpxW; oxamate amidohydrolase [EC:3.5.1.126]
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APeptidases of unknown catalytic type
B Family U32
C RBAU_2582 yrrO; putative hydrolase K08303 prtC; U32 family peptidase [EC:3.4.-.-]
C RBAU_2583 yrrN; putative hydrolase K08303 prtC; U32 family peptidase [EC:3.4.-.-]
B Family U62
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
C RBAU_1823 iseA; inhibitor of cell-separation enzymes K23598 iseA; iseA protein
B Family I87
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2024
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Classification taken and modified from MEROPS