+E Polyketide biosynthesis proteins KO #

  Polyketide Biosynthesis Proteins - Bacillus velezensis TrigoCor1448

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APolyketide synthase (PKS) B Modular type I PKS C cis-AT PKS D Erythronolide PKS D Oleandomycin synthase D Pikromycin PKS D Avermectin PKS D Tylactone synthase D Protomycinolide IV synthase D Niddamycin PKS D Rapamycin PKS D Immunomycin PKS D Ansamitocin PKS D Rifamycin PKS D Polyene macrolide PKS D Pimaricinolide synthase D Candicidin PKS D Soraphen PKS D Stigmatellin PKS D Mycolactone PKS D Coelimycin PKS D Aureothin PKS D Spectinabilin PKS D Phthiocerol / Phenolphthiocerol PKS C trans-AT PKS D Bacillanene hybrid PKS-NRPS E AJ82_08230 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_09625 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_12510 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_09620 acyltransferase K15328 pksD; bacillaene synthase trans-acting acyltransferase E AJ82_09650 polyketide synthase K13611 pksJ; bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksJ/BaeJ E AJ82_09655 polyketide synthase K13612 pksL; bacillaene polyketide synthase PksL/BaeL E AJ82_09660 polyketide synthase K13613 pksM; bacillaene polyketide synthase PksM/BaeM E AJ82_09665 polyketide synthase K13614 pksN; bacillaene biosynthesis, polyketide synthase / nonribosomal peptide synthetase PksN/BaeN E AJ82_09670 polyketide synthase K13615 pksR; bacillaene polyketide synthase PksR/BaeR D Chivosazol hybrid PKS-NRPS E AJ82_08230 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_09625 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_12510 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E ------ chiPKS; chivosazol hybrid polyketide synthase / nonribosomal peptide synthetase [SCL:sce4137 sce4136 sce4135 sce4134 sce4133] D Macrolactin PKS E AJ82_08230 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_09625 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_12510 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_08235 polyketide synthase K25842 mlnB; macrolactin polyketide synthase MlnB E AJ82_08240 polyketide synthase K25843 mlnC; macrolactin polyketide synthase MlnC E AJ82_08245 polyketide synthase K25844 mlnD; macrolactin polyketide synthase MlnD E AJ82_08250 polyketide synthase K25845 mlnE; macrolactin polyketide synthase MlnE E AJ82_08255 polyketide synthase K25846 mlnF; macrolactin polyketide synthase MlnF E AJ82_08260 polyketide synthase K25847 mlnG; macrolactin polyketide synthase MlnG E AJ82_08265 MlnH K25848 mlnH; macrolactin polyketide synthase MlnH D Difficidin PKS E AJ82_08230 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_09625 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_12510 malonyl CoA-ACP transacylase K15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains E AJ82_12480 polyketide synthase K25850 dfnE; difficidin synthase DfnE E AJ82_12475 polyketide synthase K25851 dfnF; difficidin synthase DfnF E AJ82_12470 polyketide synthase K25852 dfnG; difficidin synthase DfnG E AJ82_12465 polyketide synthase K25853 dfnH; difficidin synthase DfnH E AJ82_12460 polyketide synthase K25854 dfnI; difficidin synthase DfnI E AJ82_12455 DfnJ K25855 dfnJ; difficidin synthase DfnJ D Rhizoxin hybrid PKS-NRPS D Myxovirescin hybrid PKS-NRPS E ------ taPKS; myxovirescin biosynthesis, hybrid polyketide synthase / nonribosomal peptide synthetase [MXA:MXAN_3935 MXAN_3933 MXAN_3932] D Albicidin synthase, hybrid PKS-NRPS E ------ albXIII; albicidin synthase trans-acting acyltransferase AlbXIII [XAL:XALC_1516] E ------ albPKS; albicidin synthase, hybrid polyketide synthase / nonribosomal peptide synthetase [XAL:XALC_1529 XALC_1532 XALC_1523] D Etnangien PKS E ------ etnPKS; etnangien polyketide synthase [SCL:sce3188 sce3189 sce3190 sce3191 sce3192 sce3193] B Iterative type I PKS C Fungal nonreducing PKS (NR-PKS) C Fungal partially reducing PKS (PR-PKS) C Fungal highly reducing PKS (HR-PKS) C Fungal hybrid type D Zearalenone synthase D Asperfuranone NR/HR-PKS E ------ AFOE; asperfuranone biosynthesis, nonreducing iterative type I polyketide synthase AfoE [ANI:ANIA_01034] E ------ AFOG; asperfuranone biosynthesis, highly reducing iterative type I polyketide synthase AfoG [ANI:ANIA_01036] C Bacterial type B Type II PKS C C9-C14 cyclized polyketide type D Spore pigment PKS C C7-C14 cyclized polyketide type D Octaketide PKS D Nonaketide PKS D Decaketide PKS B Type III PKS C Plant type C Fungal type C Bacterial type D AJ82_11470 chalcone synthase K16167 bpsA; alkylresorcinol/alkylpyrone synthase D ------ arsB; alkylresorcinol synthase [AVN:Avin_29550] D ------ arsC; alkylpyrone synthase [AVN:Avin_29530] B PKS-NRPS hybrid C Bacterial type (modular) D Myxalamid hybrid PKS-NRPS D Myxothiazol hybrid PKS-NRPS E ------ mtaPKS; myxothiazol hybrid polyketide synthase / nonribosomal peptide synthetase [SUR:STAUR_4014 STAUR_4015 STAUR_4016 STAUR_4017 STAUR_4018 STAUR_4019] D Coronatine hybrid PKS-NRPS D Microcystin synthetase D Epothilone synthetase D Bleomycin synthetase D Colibactin synthetase C Fungal type (trans-ER, iterative) D Aspyridone synthetase C Fungal type (iterative) # ANonribosomal peptide synthetase (NRPS) B Linear NRPS C ------ EASA; emericellamide biosynthesis, nonribosomal peptide synthetase EasA [ANI:ANIA_02545] C ------ lgrABCD; linear pentadecapeptide gramicidin synthetase [BBE:BBR47_28920 BBR47_28930 BBR47_28940 BBR47_29500] C ------ mcnABCE; cyanopeptolin synthetase [MAR:MAE_60030 MAE_60020 MAE_60010 MAE_60000] C ACV synthetase C Bacitracin synthetase C Viomycin synthetase C Pristinamycin I synthetase C Tyrocidine synthetase C Surfactin family lipopeptide synthetase D AJ82_01995 peptide synthetase K15654 srfAA; surfactin/lichenysin synthetase A D AJ82_02015 peptide synthetase K15656 srfAC; surfactin/lichenysin synthetase C C Iturin family lipopeptide synthetase D AJ82_10330 peptide synthetase K15661 ituA; iturin family lipopeptide synthetase A D AJ82_10325 peptide synthetase K15662 ituB; iturin family lipopeptide synthetase B D AJ82_10320 peptide synthetase K15663 ituC; iturin family lipopeptide synthetase C C Fengycin family lipopeptide synthetase D AJ82_10475 peptide synthetase K15664 ppsA; plipastatin/fengycin lipopeptide synthetase A D AJ82_10470 peptide synthetase K15665 ppsB; plipastatin/fengycin lipopeptide synthetase B D AJ82_10465 peptide synthetase K15666 ppsC; plipastatin/fengycin lipopeptide synthetase C D AJ82_10460 peptide synthetase K15667 ppsD; plipastatin/fengycin lipopeptide synthetase D D AJ82_10455 ATP-dependent isoleucine adenylase K15668 ppsE; plipastatin/fengycin lipopeptide synthetase E C Arthrofactin type cyclic lipopeptide synthetase C Vancomycin synthetase C Nocardicin synthetase D AJ82_16415 antibiotic transporter K05375 mbtH; MbtH protein C Bialaphos synthetase C L-2-amino-4-methoxy-trans-3-butenoic acid synthetase B Iterative NRPS C Enterobactin synthetase D AJ82_16425 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D AJ82_16430 entE; enterobactin synthase subunit E K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Bacillibactin synthetase D AJ82_16425 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D AJ82_16430 entE; enterobactin synthase subunit E K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D AJ82_16420 diguanylate cyclase K04780 dhbF; glyine---[glycyl-carrier protein] ligase [EC:6.2.1.66] C Gramicidin synthetase B Nonlinear NRPS C Yersiniabactin synthetase C Pyochelin synthetase C Mycobactin synthetase C Vibriobactin synthetase D AJ82_16425 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D AJ82_16430 entE; enterobactin synthase subunit E K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Myxochelin synthetase D AJ82_16430 entE; enterobactin synthase subunit E K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] D AJ82_16425 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] C Petrobacin synthetase C Syringomycin synthetase C Vanchrobactin synthetase D AJ82_16425 Isochorismatase K01252 entB; bifunctional isochorismate lyase / aryl carrier protein [EC:3.3.2.1 6.3.2.14] D AJ82_16430 entE; enterobactin synthase subunit E K02363 entE; 2,3-dihydroxybenzoate---[aryl-carrier protein] ligase [EC:6.3.2.14 6.2.1.71] C Isonitrile lipopeptide synthase # APolyketide tailoring proteins B Hydrolase B Ketoreductase B Oxygenase C AJ82_09675 cytochrome P450 K15468 pksS; cytochrome P450 family 107 subfamily K polypeptide 1 B Methylase C AJ82_11465 hypothetical protein K16168 bpsB; methyltransferase B Glycosyltransferase B Halogenase B beta-Branched incorporating proteins C AJ82_09615 poly(3-hydroxyalkanoate) synthetase K15327 pksC; polyketide biosynthesis malonyl-CoA-[acyl-carrier-protein] transacylase C AJ82_05485 polyketide beta-ketoacyl:ACP synthase K00646 pksF; malonyl-[acp] decarboxylase [EC:4.1.1.124] C AJ82_09630 poly(3-hydroxyalkanoate) depolymerase K15337 acpK; polyketide biosynthesis acyl carrier protein C AJ82_09635 3-hydroxy-3-methylglutaryl-ACP synthase K15311 pksG; 3-carboxymethyl-3-hydroxy-acyl-[acp] synthase [EC:2.3.3.22] C AJ82_12445 3-hydroxy-3-methylglutaryl-ACP synthase K15311 pksG; 3-carboxymethyl-3-hydroxy-acyl-[acp] synthase [EC:2.3.3.22] C AJ82_09640 polyketide biosynthesis enoyl-CoA hydratase K15312 pksH; 3-carboxymethyl-3-hydroxy-acyl-[acp] dehydratase [EC:4.2.1.181] C AJ82_09645 polyketide biosynthesis enoyl-CoA hydratase K15313 pksI; 4-carboxy-3-alkylbut-2-enoyl-[acp] decarboxylase [EC:4.1.1.125] C AJ82_12440 polyketide biosynthesis enoyl-CoA hydratase K15313 pksI; 4-carboxy-3-alkylbut-2-enoyl-[acp] decarboxylase [EC:4.1.1.125] B Others # ANonribosomal peptide tailoring proteins B Reductase B Thioesterase C AJ82_02020 thioesterase K15657 srfATE; external thioesterase TEII B Oxygenase B Glycosyltransferase B Aminotransferase B Others ! #
#[ COMPOUND | BRITE | KEGG2 | KEGG ]
#Last updated: May 29, 2025