+E Transcription factors KO
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Transcription Factors - Bicyclus anynana (squinting bush brown)
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AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
D 112048501 X-box-binding protein 1 K09027 XBP1; X box-binding protein 1
D 112047037 transcription factor Jun K04448 JUN; transcription factor AP-1
C AP-1(-like) components, Fos
D 112058375 transcription factor kayak isoform X1 K04379 FOS; proto-oncogene protein c-fos
D 112052356 transcription factor kayak K21406 ATF3; activating transcription factor 3
C AP-1(-like) components, Maf
D 112054295 transcription factor MafA-like K07595 MAFA; transcription factor MAFA
D 112046082 transcription factor MafK K09037 MAFF_G_K; transcription factor MAFF/G/K
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
D 112043820 uncharacterized protein LOC112043820 isoform X2 K04450 ATF2; cyclic AMP-dependent transcription factor ATF-2
D 112051663 activating transcription factor of chaperone K04374 ATF4; cyclic AMP-dependent transcription factor ATF-4
C CREB
D 112052434 cyclic AMP response element-binding protein B isoform X1 K05870 CREB1; cyclic AMP-responsive element-binding protein 1
D 112053617 cyclic AMP response element-binding protein A K09048 CREB3; cyclic AMP-responsive element-binding protein 3
D 112050426 uncharacterized protein LOC112050426 K09054 ATF6A; cyclic AMP-dependent transcription factor ATF-6 alpha
C C/EBP-like factors
D 112049088 CCAAT/enhancer-binding protein gamma K10049 CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma
D 112043233 CCAAT/enhancer-binding protein K10052 CEBPN; CCAAT/enhancer binding protein (C/EBP), invertebrate
C bZIP/PAR
D 128199632 transcription factor ces-2-like K09056 DBP; albumin D box-binding protein
D 112053458 transcription factor ces-2-like K09056 DBP; albumin D box-binding protein
D 112045504 thyrotroph embryonic factor isoform X1 K09057 HLF; hepatic leukemia factor
C Plant bZIP factors
C ZIP only
D 112056105 transcription factor atf-2 K12114 VRI; vrille
D 112054461 transcription factor VBP-like K09062 GT; protein giant
D 112054466 thyrotroph embryonic factor-like K09062 GT; protein giant
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
D 112053170 protein daughterless isoform X1 K15603 TCF4_12; transcription factor 4/12
C Myogenic transcription factors
D 112052032 transcription factor SUM-1 K18484 MYF5; myogenic factor 5
C Achaete-Scute
D 112055615 achaete-scute complex protein T3 K09067 ASCL; achaete-scute complex protein
D 112050300 achaete-scute complex protein T3-like K09067 ASCL; achaete-scute complex protein
D 112050318 achaete-scute complex protein T3-like K09067 ASCL; achaete-scute complex protein
D 112046021 neurogenic differentiation factor 1-like K09067 ASCL; achaete-scute complex protein
C Tal/Twist/Atonal/Hen, Lymphoid factors
D 112051998 uncharacterized protein LOC112051998 isoform X1 K09068 TAL; T-cell acute lymphocytic leukemia protein
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
D 112049514 protein Fer3-like K09069 TWIST; twist
D 112057243 transcription factor 15 isoform X1 K09070 TCF15; transcription factor 15
D 112048856 heart- and neural crest derivatives-expressed protein 2 isoform X1 K18486 HAND2; heart-and neural crest derivatives-expressed protein 2
D 112044715 transcription factor 21 K09072 MSC; musculin (activated B-cell factor-1)
D 112048315 pancreas transcription factor 1 subunit alpha K09073 PTF1A; pancreas-specific transcription factor 1a
D 112058390 protein Fer3-like K22400 FERD3L; Fer3-like protein
C Tal/Twist/Atonal/Hen, HEN
D 112056637 helix-loop-helix protein 1 K09075 NHLH; nescient helix-loop-helix protein
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
D 112047898 protein atonal-like K09083 ATOH1_7; atonal protein 1/7
D 112055221 transcription factor ATOH8 K09084 ATOH8; atonal protein 8
D 112054528 protein dimmed K08040 BHLHB8; class B basic helix-loop-helix protein 8
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
D 112048538 NADPH oxidase activator-like K09090 HESN; hairy and enhancer of split, invertebrate
D 112051896 hairy/enhancer-of-split related with YRPW motif protein 1 K09090 HESN; hairy and enhancer of split, invertebrate
D 112045264 enhancer of split mbeta protein-like K09090 HESN; hairy and enhancer of split, invertebrate
D 112043553 protein hairy K09090 HESN; hairy and enhancer of split, invertebrate
D 112051893 enhancer of split mbeta protein-like K09090 HESN; hairy and enhancer of split, invertebrate
D 112049903 hairy/enhancer-of-split related with YRPW motif protein K09091 HEY; hairy and enhancer of split related with YRPW motif
D 112047231 transcription factor cwo isoform X1 K27237 CWO; transcription factor CWO
C Hairy, Fungal regulators
C Factors with PAS domain
D 112043391 aryl hydrocarbon receptor isoform X2 K09093 AHR; aryl hydrocarbon receptor
D 112058365 hypoxia-inducible factor 1-alpha isoform X1 K08268 HIF1A; hypoxia-inducible factor 1 alpha
D 112046886 aryl hydrocarbon receptor nuclear translocator homolog isoform X1 K09097 ARNT; aryl hydrocarbon receptor nuclear translocator
D 112046576 protein trachealess isoform X3 K09098 NPAS1_3; neuronal PAS domain-containing protein 1/3
D 112046861 PAS domain-containing protein cky-1-like K26457 NPAS4; neuronal PAS domain-containing protein 4
D 112046622 PAS domain-containing protein cky-1-like isoform X1 K26457 NPAS4; neuronal PAS domain-containing protein 4
D 112057195 circadian locomoter output cycles protein kaput isoform X1 K02223 CLOCK; circadian locomoter output cycles kaput protein [EC:2.3.1.48]
D 112055514 protein cycle isoform X1 K02296 ARNTL; aryl hydrocarbon receptor nuclear translocator-like protein 1
D 112045799 single-minded homolog 1 isoform X1 K09100 SIM; single-minded
C Yabby
C INO
C HLH domain only
D 112044717 protein extra-macrochaetae K17696 EMC; DNA-binding protein inhibitor ID, other
D 112053089 transcription factor collier isoform X1 K09103 EBF; early B-cell factor
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
D 112051842 upstream stimulatory factor 2 K09106 USF; upstream stimulatory factor
D 112056120 sterol regulatory element-binding protein 1 K07197 SREBP1; sterol regulatory element-binding transcription factor 1
D 112043929 transcription factor AP-4 K09108 TFAP4; transcription factor AP-4
C Cell cycle controlling factors, Myc
D 112046269 myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
C Cell cycle controlling factors, Mad/Max
D 112044316 protein max isoform X1 K04453 MAX; Max protein
D 112042875 max-like protein X K09113 MLX; MAX-like protein X
D 112049412 max dimerization protein 4-like isoform X1 K09114 MXD; MAX dimerization protein
D 112049929 max-binding protein MNT isoform X1 K09115 MNT; MAX-binding protein
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
D 112055300 nuclear factor 1 B-type isoform X1 K09172 NFIN; nuclear factor I, invertebrate
C RF-X
D 112047386 transcription factor RFX3 K09173 RFX1_2_3; regulatory factor X 1/2/3
D 112045630 uncharacterized protein LOC112045630 K09175 RFX7; DNA-binding protein RFX7
C AP-2 (bHSH)
D 112052398 transcription factor AP-2-epsilon K09180 TFAP2N; transcription factor AP-2, invertebrate
B Zinc finger
C Cys4 thyroid hormone receptor-like
D 112052885 ecdysone-inducible protein E75 isoform X1 K08701 NR1D3; nuclear receptor subfamily 1 group D member 3
D 112056919 probable nuclear hormone receptor HR3 isoform X1 K14033 NR1F4; nuclear receptor subfamily 1 group F member 4
D 112043737 ecdysone receptor isoform X1 K14034 NR1H1; ecdysone receptor
D 112049558 nuclear hormone receptor HR96 K14035 NR1IN; nuclear receptor subfamily 1 group I
C Cys4 hepatocyte nuclear factor 4-like
D 112057996 hepatocyte nuclear factor 4-gamma isoform X1 K08704 NR2A4; hepatocyte nuclear factor 4
D 112047418 protein ultraspiracle homolog isoform X1 K14030 NR2B4; nuclear receptor subfamily 2 group B member 4
D 112056206 nuclear receptor subfamily 2 group C member 2 isoform X1 K08543 NR2C1; testicular receptor 2
D 112045046 protein dissatisfaction K08545 NR2E1; nuclear receptor subfamily 2 group E member 1
D 112053835 nuclear receptor subfamily 2 group E member 1-like K08545 NR2E1; nuclear receptor subfamily 2 group E member 1
D 112043779 photoreceptor-specific nuclear receptor K08546 NR2E3; nuclear receptor subfamily 2 group E member 3
D 112048597 steroid receptor seven-up, isoforms B/C K14032 NR2F3; nuclear receptor subfamily 2 group F member 3
C Cys4 estrogen receptor-like
D 112046916 steroid hormone receptor ERR2 isoform X1 K08703 NR3BN; estrogen-related receptor ERR
C Cys4 nerve growth factor IB-like
D 112044883 probable nuclear hormone receptor HR38 K08558 NR4A2; nuclear receptor subfamily 4 group A member 2
C Cys4 Fushi tarazu-F1-like
D 112048033 nuclear hormone receptor FTZ-F1 isoform X1 K08705 NR5A3; nuclear receptor subfamily 5 group A member 3
D 112053467 nuclear hormone receptor FTZ-F1 beta K08705 NR5A3; nuclear receptor subfamily 5 group A member 3
C Cys4 germ cell nuclear factor
D 112055319 hormone receptor 4 isoform X1 K09185 NR6AN; nuclear receptor subfamily 6 group A
C Cys4 Knirps/DAX1-like
D 112043430 knirps-related protein-like K08706 NR0AN; nuclear receptor subfamily 0 group A
D 112043431 protein embryonic gonad K08706 NR0AN; nuclear receptor subfamily 0 group A
C Cys4 GATA-factors
D 112058203 GATA-binding factor C isoform X1 K17894 GATA2; GATA-binding protein 2
D 112049848 transcription factor GATA-4-like K09183 GATA4; GATA-binding protein 4
D 112043747 GATA zinc finger domain-containing protein 1 K23407 GATAD1; GATA zinc finger domain-containing protein 1
D 112047441 transcriptional repressor p66-alpha K23194 GATAD2; transcriptional repressor p66
D 112048529 arginine-glutamic acid dipeptide repeats protein K05628 RERE; arginine-glutamic acid dipeptide repeats protein
D 112046452 metastasis-associated protein MTA3 K11660 MTA; metastasis-associated protein MTA
D 112046682 transcriptional regulator ATRX homolog isoform X1 K10779 ATRX; transcriptional regulator ATRX
C Cys2His2 SP/KLF family and related proteins
D 112054442 transcription factor Sp4 isoform X1 K09194 SP4; transcription factor Sp4
D 112053460 transcription factor Sp9 isoform X1 K09199 SP9; transcription factor Sp9
D 112053215 dendritic arbor reduction protein 1 isoform X1 K09206 KLF5; krueppel-like factor 5
D 112058613 Krueppel-like factor 3 K09206 KLF5; krueppel-like factor 5
D 112047864 Krueppel-like factor luna isoform X1 K09207 KLF6_7; krueppel-like factor 6/7
D 112055404 zinc finger protein 358 K12379 HKB; huckebein
C Cys2His2 GLI-like
D 112048258 zinc finger protein GLI1-like K09232 GLIS1_3; zinc finger protein GLIS1/3
D 112054806 zinc finger protein GLIS2 K09233 GLIS2; zinc finger protein GLIS2
D 112045649 zinc finger protein ZIC 4 K09227 ZICN; zinc finger protein ZIC, invertebrate
D 112046560 transcriptional activator cubitus interruptus K16799 CI; transcriptional activator cubitus interruptus
C Cys2His2 Snail
D 112058590 zinc finger protein SNAI2-like K05706 SNAI2; snail 2
D 112046294 transcriptional repressor scratch 2-like K09219 SCRT; scratch
D 112047230 MDS1 and EVI1 complex locus protein EVI1-A-like K25795 INSM; insulinoma-associated protein
C Cys2His2 BTB-ZF factors
D 112058094 zinc finger protein 121 K24385 MYNN; myoneurin
D 112047298 protein tramtrack, beta isoform isoform X1 K09237 TTK; tramtrack
D 112047636 broad-complex core protein isoforms 1/2/3/4/5 isoform X1 K02174 BR-C; broad-complex core protein
C Cys2His2 BED
D 112050772 zinc finger BED domain-containing protein 4 K24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]
C Cys2His2 PRDM
D 112048387 uncharacterized protein LOC112048387 isoform X1 K24501 PRDM1; PR domain zinc finger protein 1 [EC:2.1.1.-]
D 112048943 histone-lysine N-methyltransferase PRDM16 K04462 MECOM; [histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:2.1.1.367]
D 112050999 PR domain zinc finger protein 5 isoform X1 K22534 PRDM5; PR domain zinc finger protein 5 [EC:2.1.1.-]
D 112045806 zinc finger protein OZF K22534 PRDM5; PR domain zinc finger protein 5 [EC:2.1.1.-]
D 112058226 uncharacterized protein LOC112058226 K20797 PRDM8; PR domain zinc finger protein 8 [EC:2.1.1.-]
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
D 112044996 protein sister of odd and bowel-like K09215 OSR; odd-skipped
D 112044997 protein odd-skipped K09215 OSR; odd-skipped
D 112044995 protein bowel K09215 OSR; odd-skipped
D 112056445 transcriptional regulator ovo isoform X1 K09216 OVOL; ovo
D 112048732 zinc finger protein Gfi-1 K09223 GFI1; growth factor independent 1
D 112050060 fez family zinc finger protein erm K09223 GFI1; growth factor independent 1
D 112043028 uncharacterized protein LOC112043028 isoform X1 K09239 HIVEP; human immunodeficiency virus type I enhancer-binding protein
D 112051540 zinc finger protein PLAGL1-like K19484 PLAG1; zinc finger protein PLAG1
D 112051226 uncharacterized protein LOC112051226 K20210 RREB1; ras-responsive element-binding protein 1
D 112057850 B-cell lymphoma/leukemia 11A isoform X2 K22045 BCL11A; B-cell lymphoma/leukemia 11A
D 112047797 transcriptional repressor CTCF isoform X1 K23195 CTCF; transcriptional repressor CTCF
D 112045192 uncharacterized protein LOC112045192 isoform X1 K23317 MTF1; metal regulatory transcription factor 1
D 112046369 zinc finger protein basonuclin-2-like K24146 BNC; zinc finger protein basonuclin
D 112046383 zinc finger protein basonuclin-2-like K24146 BNC; zinc finger protein basonuclin
D 112052019 transcriptional repressor protein YY1 isoform X1 K09201 YY; transcription factor YY
D 112046202 replication protein A 70 kDa DNA-binding subunit K07466 RFA1; replication factor A1
D 112056136 zinc finger and BTB domain-containing protein 17 isoform X1 K23480 ZNF362_384; zinc finger protein 362/384
D 112056645 zinc finger protein rotund-like isoform X4 K23480 ZNF362_384; zinc finger protein 362/384
D 112049625 zinc finger protein 423 homolog isoform X3 K22870 ZNF423; zinc finger protein 423
D 112047011 zinc finger protein 79 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112047088 zinc finger protein 25 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112047090 zinc finger protein 62 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112047093 zinc finger protein 555 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112047117 zinc finger protein 551 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112047121 zinc finger protein 615 isoform X2 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112047122 zinc finger protein 709 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112047472 zinc finger protein 551-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 112047738 zinc finger protein 2 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112055735 zinc finger protein 271-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112055786 gastrula zinc finger protein XlCGF46.1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112056004 zinc finger protein 182-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112048272 zinc finger protein 891 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112048544 zinc finger protein 699 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112048852 protein suppressor of hairy wing-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 112048939 zinc finger protein 525 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112057015 zinc finger protein ZFP2 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112049214 zinc finger protein ZFP2 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112049372 zinc finger protein 260 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112049376 gastrula zinc finger protein XlCGF57.1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112058092 zinc finger protein 271 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112049495 zinc finger protein 37 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112058413 zinc finger protein 189 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112043044 zinc finger protein 470 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112050594 zinc finger protein 431 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112050786 zinc finger protein 567 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112043627 zinc finger protein 436-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112051119 zinc finger protein 91 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112051127 zinc finger imprinted 3 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112051237 zinc finger protein 224 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112051255 zinc finger protein 501 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112043909 PR domain zinc finger protein 15 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112051707 gastrula zinc finger protein XlCGF57.1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112052433 zinc finger protein 26 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112052879 gastrula zinc finger protein XlCGF52.1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112045536 zinc finger protein 816 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112045558 zinc finger protein 431 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112053067 zinc finger protein 12 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112053393 zinc finger protein 33B K09228 KRAB; KRAB domain-containing zinc finger protein
D 112045796 zinc finger protein 436 isoform X2 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112053808 PR domain zinc finger protein 5 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112050505 zinc finger protein 28 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112043448 zinc finger protein 271 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 128199555 zinc finger protein 431-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112045580 zinc finger protein 431-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112057586 zinc finger protein 568-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 112055132 zinc finger protein 568-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112056823 zinc finger protein 84-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 128199595 zinc finger protein 271-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 128199620 gastrula zinc finger protein XlCGF26.1-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 112052515 gastrula zinc finger protein XlCGF57.1-like K09228 KRAB; KRAB domain-containing zinc finger protein
D 128199675 zinc finger protein 271-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112057567 zinc finger protein 271 isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112054056 zinc finger protein 271-like isoform X1 K09228 KRAB; KRAB domain-containing zinc finger protein
D 112046999 fez family zinc finger protein erm-like K24502 FEZF; Fez family zinc finger protein
D 112047366 uncharacterized protein LOC112047366 isoform X2 K25209 CASZ1; zinc finger protein castor
D 112049443 histone H4 transcription factor K25794 HINFP; histone H4 transcription factor
D 112055123 protein krueppel-like K09231 KR; krueppel
D 112048899 Krueppel-like factor 16 K13943 CBT; cabut
D 112058025 protein hunchback-like K09213 HB; hunchback
D 112049470 protein glass K09214 GL; glass
D 112045021 protein drumstick K22535 DRM; drumstick
C Cys2HisCys zinc factors
D 112047931 zinc finger protein ush isoform X3 K17441 ZFPM1; zinc finger protein ZFPM1
D 112053759 histone acetyltransferase KAT8-like K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D 112050434 histone acetyltransferase KAT8-like K11308 MYST1; histone acetyltransferase MYST1 [EC:2.3.1.48]
D 112058507 histone acetyltransferase KAT7 K11307 MYST2; histone acetyltransferase MYST2 [EC:2.3.1.48]
D 112051853 histone acetyltransferase KAT6B isoform X1 K11306 MYST4; histone acetyltransferase MYST4 [EC:2.3.1.48]
D 112052347 histone acetyltransferase Tip60 K11304 TIP60; histone acetyltransferase HTATIP [EC:2.3.1.48]
D 112052724 uncharacterized protein LOC112052724 isoform X1 K24387 L3MBTL; lethal(3)malignant brain tumor-like protein
C Cys3His zinc factors
D 112045874 roquin-1 K15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein
D 112044045 uncharacterized protein DDB_G0288805 isoform X1 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
C Cys2CysHis zinc factors
D 112047790 THAP domain-containing protein 1 K23203 THAP1_3; THAP domain-containing protein 1/3
C CXXC CpG-binding proteins
D 112051161 histone-lysine N-methyltransferase trithorax isoform X1 K09186 MLL1; [histone H3]-lysine4 N-trimethyltransferase MLL1 [EC:2.1.1.354]
D 112058369 CXXC-type zinc finger protein 1 K14960 CXXC1; COMPASS component SPP1
D 112052909 CXXC-type zinc finger protein 1 isoform X1 K14960 CXXC1; COMPASS component SPP1
D 112047331 methylcytosine dioxygenase TET isoform X1 K24309 TET2_3; methylcytosine dioxygenase TET2/3 [EC:1.14.11.80]
D 112047809 DNA (cytosine-5)-methyltransferase 1 isoform X1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 112043560 DNA (cytosine-5)-methyltransferase 1 K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D 112053444 jmjC domain-containing histone demethylation protein 1 isoform X1 K10276 FBXL10_11; F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
D 112046596 uncharacterized protein LOC112046596 K11485 MTF2; metal regulatory transcription factor 2
D 112056927 protein shuttle craft K12236 NFX1; transcriptional repressor NF-X1
D 112047033 CCHC-type zinc finger nucleic acid binding protein K09250 CNBP; cellular nucleic acid-binding protein
D 112044502 zinc finger C4H2 domain-containing protein isoform X1 K24369 ZC4H2; zinc finger C4H2 domain-contaning protein
D 112056562 interferon regulatory factor 2-binding protein-like A K22383 IRF2BP; interferon regulatory factor 2-binding protein
B Helix-turn-helix
C Homeo domain ANTP: HOXL
D 112046991 homeobox protein Hox-B1b-like K09301 HOX_1; homeobox protein HoxA/B/D1
D 112057771 homeotic protein proboscipedia K09302 HOX_2; homeobox protein HoxA/B2
D 112057772 homeobox protein DTH-1-like K09303 HOX_3; homeobox protein HoxA/B/D3
D 112057793 homeobox protein DLX-3-like K09303 HOX_3; homeobox protein HoxA/B/D3
D 112057774 homeobox protein Hox-C4 K09304 HOX_4; homeobox protein HoxA/B/C/D4
D 112057777 homeotic protein Sex combs reduced K09305 HOX_5; homeobox protein HoxA/B/C5
D 112057778 homeobox protein Hox-B5a K09307 HOX_7; homeobox protein HoxA/B7
D 112057779 homeotic protein antennapedia K09307 HOX_7; homeobox protein HoxA/B7
D 112057782 homeotic protein ultrabithorax K09307 HOX_7; homeobox protein HoxA/B7
D 112057784 homeobox protein abdominal-A homolog isoform X1 K09307 HOX_7; homeobox protein HoxA/B7
D 112044183 homeobox protein Hox-C4a-like K09310 GSH; homeobox protein GSH
D 112055412 homeobox protein CDX-1 isoform X2 K09312 CDX1_4; homeobox protein CDX1/4
D 112057798 retinal homeobox protein Rx2-like K09320 EVX; homeobox even-skipped homolog protein
D 112051685 segmentation protein even-skipped-like isoform X1 K09320 EVX; homeobox even-skipped homolog protein
D 112048243 homeobox protein GBX-1 K09321 GBX; homeobox protein GBX
D 128198844 homeobox protein Hox-B4-like K09322 MEOX; homeobox protein MOX
D 112057786 homeobox protein abdominal-B isoform X1 K09300 ABDB; homeobox protein abdominal-B and related proteins
C Homeo domain ANTP: NKL
D 112045425 homeobox protein slou K09309 NKX1; homeobox protein Nkx-1
D 112054758 thyroid transcription factor 1-like K09342 NKX2-1; homeobox protein Nkx-2.1
D 112053919 homeobox protein vnd-like K08029 NKX2-2; homeobox protein Nkx-2.2
D 112047853 homeobox protein Dlx6a-like K09343 NKX2-3; homeobox protein Nkx-2.3
D 112053316 homeobox protein bagpipe-like K09995 NKX3-2; homeobox protein Nkx-3.2
D 112043977 homeobox protein HMX3-B-like K09349 NKX5; homeobox protein Nkx-5
D 112055223 homeotic protein distal-less isoform X1 K18488 DLX2; homeobox protein DLX2
D 112051741 T-cell leukemia homeobox protein 2-like K15607 TLX3; T-cell leukemia homeobox protein 3
D 112048172 homeobox protein DBX1-B-like K09339 HLX1; homeobox protein HLX1
D 112044014 homeotic protein empty spiracles-like K09317 EMX; homeobox protein EMX
D 112053006 homeobox protein invected-like isoform X1 K09319 EN; homeobox protein engrailed
D 112053007 segmentation polarity homeobox protein engrailed K09319 EN; homeobox protein engrailed
D 112047193 homeobox protein MSX-2-like K09341 MSX; homeobox protein MSX
D 112047854 muscle segmentation homeobox-like K09341 MSX; homeobox protein MSX
D 112047859 muscle segmentation homeobox K09341 MSX; homeobox protein MSX
D 112053314 homeobox protein BarH-like 1b isoform X1 K09353 LBX; homeobox protein LBX
D 112043836 hematopoietically-expressed homeobox protein hhex-like K08024 HHEX; homeobox protein HEX
D 112051348 homeobox protein B-H1-like K09360 BARHL; BarH-like
D 112042835 brain-specific homeobox protein homolog K24874 BSX; brain-specific homeobox protein
D 112050368 homeobox protein engrailed-like SMOX-2 K24875 DBX; homeobox protein DBX
C Homeo domain Paired-related
D 112054675 homeobox protein aristaless isoform X1 K09452 ARX; homeobox protein aristaless-related
D 112056678 homeobox protein aristaless K09452 ARX; homeobox protein aristaless-related
D 112046545 paired box protein Pax-6-like K09452 ARX; homeobox protein aristaless-related
D 112043320 homeobox protein aristaless-like 3 K09451 ALX4; homeobox protein aristaless-like 4
D 112044796 retina and anterior neural fold homeobox protein 2-like K09324 GSC; homeobox protein goosecoid
D 112055086 homeobox protein OTX1 isoform X1 K09326 OTX1; homeobox protein OTX1
D 112052864 homeobox protein unc-4-like K09328 UNC4; homeobox protein Unc-4
D 112057036 homeotic protein ocelliless-like K09329 PRRX; paired mesoderm homeobox protein
D 112052469 paired mesoderm homeobox protein 2B-like K09330 PHOX2; paired mesoderm homeobox protein 2
D 112052085 short stature homeobox protein 2-like K09331 SHOX; short stature homeobox protein
D 112051930 retinal homeobox protein Rx1-like K09332 RAX; retina and anterior neural fold homeobox protein
D 112054788 visual system homeobox 2-like isoform X1 K09336 VSX2; visual system homeobox protein 2
D 112044601 dorsal root ganglia homeobox protein-like K24895 DRGX; dorsal root ganglia homeobox protein
D 112051926 homeobox protein orthopedia-like K24901 OTP; homeobox protein orthopedia
D 112050541 paired box protein Pax-1 K09382 PAX1_9; paired box protein 1/9
D 112056518 paired box protein Pax-5 isoform X1 K15608 PAX2; paired box protein 2
D 112045587 protein gooseberry isoform X1 K09381 PAX3_7; paired box protein 3/7
D 112047137 paired box protein Pax-6 isoform X1 K08031 PAX6; paired box protein 6
D 112050962 paired box protein Pax-6-like K08031 PAX6; paired box protein 6
D 112055116 paired box protein Pax-6-like isoform X1 K08031 PAX6; paired box protein 6
C Homeo domain LIM
D 112048867 insulin gene enhancer protein ISL-1 K09370 ISL1; insulin gene enhancer protein ISL-1
D 112043801 LIM homeobox transcription factor 1-beta K09371 LMX1; LIM homeobox transcription factor 1
D 112054918 LIM/homeobox protein Lhx5 isoform X1 K09372 LHX1; LIM homeobox protein 1
D 112045833 LIM/homeobox protein Lhx2 K09373 LHX2_9; LIM homeobox protein 2/9
D 112045866 protein apterous K09373 LHX2_9; LIM homeobox protein 2/9
D 112044899 LIM/homeobox protein Lhx3 isoform X1 K09374 LHX3_4; LIM homeobox protein 3/4
D 112050429 LIM/homeobox protein Awh K09375 LHX6_8; LIM homeobox protein 6/8
D 112052465 muscle LIM protein Mlp84B isoform X2 K09377 CSRP; cysteine and glycine-rich protein
C Homeo domain POU
D 112053646 POU domain, class 2, transcription factor 3L-like K09364 POU2F; POU domain transcription factor, class 2
D 112055872 silk gland factor 3 K09365 POU3F; POU domain transcription factor, class 3
D 112045880 inhibitory POU protein isoform X1 K09366 POU4F; POU domain transcription factor, class 4
D 112048768 POU domain, class 6, transcription factor 2 isoform X4 K09368 POU6F; POU domain transcription factor, class 6
C Homeo domain SINE
D 112046084 homeobox protein SIX2 K19472 SIX2; homeobox protein SIX2
D 112044525 homeobox protein SIX6-like K19473 SIX3_6; homeobox protein SIX3/6
D 112058106 uncharacterized protein LOC112058106 K15615 SIX4; homeobox protein SIX4
C Homeo domain ZF
D 112046569 zinc finger homeobox protein 4 K09378 ZFHX3; zinc finger homeobox protein 3
D 112051909 zinc finger protein 1 isoform X1 K23560 ZEB2; zinc finger homeobox protein 2
C Homeo domain CUT
D 112051626 homeobox protein cut isoform X1 K09313 CUTL; homeobox protein cut-like
D 112055301 hepatocyte nuclear factor 6 K08026 ONECUT1; one cut domain, family member 1 (hepatocyte nuclear factor 6)
C Homeo domain PROS
D 112058346 homeobox protein prospero isoform X1 K20211 PROX1; prospero homeobox 1
C Homeo domain TALE
D 112056072 homeobox protein extradenticle isoform X1 K09355 PBX1; pre-B-cell leukemia transcription factor 1
D 112047058 uncharacterized protein LOC112047058 isoform X1 K19383 TGIF1; homeobox protein TGIF1
D 112047943 uncharacterized protein LOC112047943 isoform X1 K19383 TGIF1; homeobox protein TGIF1
D 112045732 homeobox protein araucan isoform X1 K24889 IRX; iroquois-class homeodomain protein IRX
D 112045741 homeobox protein caupolican isoform X1 K24889 IRX; iroquois-class homeodomain protein IRX
D 112048682 iroquois-class homeodomain protein irx-5 K24890 MKX; homeobox protein Mohawk
D 112054591 homeobox protein homothorax isoform X3 K16672 HTH; homeobox protein homothorax
C Homeo domain other
D 112057765 homeobox protein rough-like K09362 K09362; homeo domain only family, other
C Fork head/winged helix developmental regulators
D 112058387 silk gland factor 1 K08035 FOXA2; forkhead box protein A2, hepatocyte nuclear factor 3-beta
D 112058309 fork head domain-containing protein crocodile-like K09396 FOXC; forkhead box protein C
D 112048829 fork head domain transcription factor slp2-like K09385 FOXG; forkhead box protein G
D 112048837 fork head domain transcription factor slp2-like K09385 FOXG; forkhead box protein G
D 112058157 uncharacterized protein LOC112058157 isoform X1 K09407 FOXN; forkhead box protein N
D 112056130 forkhead box protein N3-like isoform X1 K09407 FOXN; forkhead box protein N
C Fork head/winged helix tissue-specific regulators
D 112048083 forkhead box protein J1-A-like K09402 FOXJ1; forkhead box protein J1
C Fork head/winged helix cell cycle-controlling factors, E2F
D 112042864 transcription factor E2F2 isoform X1 K09389 E2F2; transcription factor E2F2
D 112055668 transcription factor E2F4 K04682 E2F4_5; transcription factor E2F4/5
D 112054320 transcription factor E2F7 K09391 E2F7_8; transcription factor E2F7/8
C Fork head/winged helix cell cycle-controlling factors, DP
D 112058605 transcription factor Dp-1 isoform X1 K04683 TFDP1; transcription factor Dp-1
C Fork head/winged helix other regulators
D 112052774 forkhead box protein D5-like K09397 FOXD; forkhead box protein D
D 112046780 forkhead box protein F1-like K09399 FOXF; forkhead box protein F
D 112053292 forkhead box protein I2 K09403 FOXJ2_3; forkhead box protein J2/3
D 112046537 forkhead box protein K1 isoform X1 K09404 FOXK; forkhead box protein K
D 112042844 forkhead box protein O isoform X1 K09408 FOXO3; forkhead box protein O3
D 112048259 forkhead box protein P1 K23582 FOXP1; forkhead box protein P1
D 112053828 fork head domain-containing protein FD4-like K09411 FOXX; forkhead box protein, other
D 112053829 fork head domain-containing protein FD4-like K09411 FOXX; forkhead box protein, other
C Heat shock factors
D 112049613 heat shock factor protein isoform X1 K09414 HSF1; heat shock transcription factor 1
C Tryptophan clusters Myb, Myb-factors
D 112045610 myb protein isoform X1 K21769 MYBL2; myb-related protein B
C Tryptophan clusters Myb, Myb-like factors
D 112048080 transcription factor Adf-1-like K09427 ADF1; Adh transcription factor 1
D 112051752 uncharacterized protein LOC112051752 K09427 ADF1; Adh transcription factor 1
D 112055931 transcription factor Adf-1 K09427 ADF1; Adh transcription factor 1
D 112056440 transcription factor Adf-1 K09427 ADF1; Adh transcription factor 1
D 112051753 uncharacterized protein LOC112051753 K09427 ADF1; Adh transcription factor 1
D 112045958 uncharacterized protein LOC112045958 K09427 ADF1; Adh transcription factor 1
C Tryptophan clusters Ets-type
D 112051403 uncharacterized protein LOC112051403 isoform X1 K09428 ELF1_2_4; E74-like factor 1/2/4
D 112053799 ETS-related transcription factor Elf-3 K17102 EHF; ETS homologous factor
D 112049197 ets DNA-binding protein pokkuri K03211 ETV6_7; ETS translocation variant 6/7
D 112044315 ETS-like protein pointed K02678 ETS1; C-ets-1
D 112042889 DNA-binding protein D-ETS-3 isoform X1 K09436 FLI1; friend leukemia integration 1 transcription factor
D 112047758 DNA-binding protein Ets97D isoform X1 K09441 GABPA; GA-binding protein transcription factor, alpha
D 112047597 DNA-binding protein D-ETS-4 isoform X1 K09442 SPDEF; SAM pointed domain-containing ETS transcription factor
D 112043654 DNA-binding protein D-ETS-6-like isoform X1 K09443 K09443; ETS-type family, other
C Tryptophan clusters interferon-regulating factors
C TEA domain
D 112049271 protein scalloped isoform X1 K09448 TEAD; transcriptional enhancer factor
C ARID
D 112046638 trithorax group protein osa isoform X1 K11653 ARID1; AT-rich interactive domain-containing protein 1
D 112042920 protein dead ringer isoform X3 K25856 ARID3; AT-rich interactive domain-containing protein 3
D 112044270 AT-rich interactive domain-containing protein 4A isoform X1 K19195 ARID4B; AT-rich interactive domain-containing protein 4B
D 112053811 uncharacterized protein LOC112053811 K25857 ARID5; AT-rich interactive domain-containing protein 5
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
D 112053564 uncharacterized protein LOC112053564 K02580 NFKB1; nuclear factor NF-kappa-B p105 subunit
D 112048826 embryonic polarity protein dorsal isoform X1 K09254 REL; c-Rel proto-oncogene protein
C RHR (Rel homology region) Ankyrin only
D 112043665 NF-kappa-B inhibitor cactus K04734 NFKBIA; NF-kappa-B inhibitor alpha
D 112051486 tonsoku-like protein K09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2
C RHR (Rel homology region) NF-AT
D 112049338 uncharacterized protein LOC112049338 isoform X2 K17335 NFAT5; nuclear factor of activated T-cells 5
C STAT
D 112051221 signal transducer and activator of transcription 5B isoform X1 K11224 STAT5B; signal transducer and activator of transcription 5B
C p53
D 112042832 cellular tumor antigen p53 K04451 TP53; tumor protein p53
C MADS-box regulators of differentiation, MEF-2
D 112048189 myocyte-specific enhancer factor 2 isoform X1 K09260 MEF2A; MADS-box transcription enhancer factor 2A
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
D 112050897 serum response factor homolog isoform X1 K04378 SRF; serum response factor
C SAND domain-containing proteins
D 112045868 deformed epidermal autoregulatory factor 1 K23041 DEAF1; deformed epidermal autoregulatory factor 1
C TATA-binding proteins
D 112044786 uncharacterized protein LOC112044786 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D 112044793 TATA-box-binding protein K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
D 112057183 TATA box-binding protein-like 1 isoform X1 K03120 TBP; transcription initiation factor TFIID TATA-box-binding protein
C HMG SOX
D 112051870 SOX domain-containing protein dichaete K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 112051875 transcription factor sox-2-like K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 112051876 transcription factor SOX-14-like K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 112054091 transcription factor SOX-21-like K09267 SOX1S; transcription factor SOX1/3/14/21 (SOX group B)
D 112058304 transcription factor Sox-14 K16796 SOX2; transcription factor SOX2 (SOX group B)
D 112048339 transcription factor Sox-12 isoform X1 K23581 SOX4; transcription factor SOX4 (SOX group C)
D 112051487 transcription factor Sox-5 K09269 SOX5_6_13; transcription factor SOX5/6/13 (SOX group D)
D 112046310 uncharacterized protein LOC112046310 isoform X1 K20225 CIC; capicua transcriptional repressor
D 112055898 uncharacterized protein LOC112055898 K21643 BBX; HMG box transcription factor BBX
C HMG TCF-1
D 112058326 protein pangolin, isoforms A/H/I/S isoform X1 K04491 TCF7L2; transcription factor 7-like 2
C HMG2-related
D 112048198 FACT complex subunit Ssrp1 K09272 SSRP1; FACT complex subunit SSRP1/POB3
C UBF
C Other HMG box factors
C Heteromeric CCAAT factors
D 112051082 nuclear transcription factor Y subunit alpha K08064 NFYA; nuclear transcription factor Y, alpha
D 112045065 uncharacterized protein LOC112045065 K08065 NFYB; nuclear transcription Y subunit beta
D 112055996 nuclear transcription factor Y subunit gamma isoform X1 K08066 NFYC; nuclear transcription factor Y, gamma
C Grainyhead
D 112046894 protein grainyhead isoform X1 K09275 TFCP2; transcription factor CP2 and related proteins
D 112045935 transcription factor CP2-like protein 1 isoform X1 K09275 TFCP2; transcription factor CP2 and related proteins
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
D 112047844 Y-box factor homolog K09276 YBX1; Y-box-binding protein 1
C Cold-shock domain factors, FRG Y2-like
C Runt
D 112045253 runt-related transcription factor 3 K08367 RUNX1; runt-related transcription factor 1
D 112045254 segmentation protein Runt-like K20213 RUN; RUNX transcription factor Runt
D 112045245 protein lozenge K20214 LZ; RUNX transcription factor Lozenge
C MYRF
D 112045120 uncharacterized protein LOC112045120 isoform X2 K24768 MYRF; myelin regulatory factor [EC:3.4.-.-]
B Other transcription factors
C HMGI(Y)
D 112048559 high mobility group protein HMGI-C K09283 HMGA2; high mobility group AT-hook protein 2
C NUPR
D 112057189 nuclear protein 1 K15626 NUPR1; nuclear protein 1
E Line #4
C Pocket domain Rb
D 112058002 retinoblastoma-like protein 1 K04681 RBL1; retinoblastoma-like protein 1
C Pocket domain CBP
D 112047417 histone lysine acetyltransferase CREBBP isoform X1 K04498 EP300; E1A/CREB-binding protein [EC:2.3.1.48]
C T-box
D 112057712 T-related protein K10172 BRA; brachyury protein
D 112055356 T-box transcription factor TBX1-like K10175 TBX1; T-box protein 1
D 112048640 optomotor-blind protein isoform X6 K10176 TBX2; T-box protein 2
D 112043550 T-box transcription factor TBX6 isoform X1 K10180 TBX6; T-box protein 6
D 112048684 T-box transcription factor TBX20-like isoform X1 K10185 TBX20; T-box protein 20
D 112048683 T-box transcription factor TBX20-like isoform X1 K10185 TBX20; T-box protein 20
C DMRT
D 112047805 doublesex- and mab-3-related transcription factor A2 K19491 DMRT4_5; doublesex- and mab-3-related transcription factor 4/5
C LRRFIP
C TCP
C AP2/ERF
C WRKY
C LOB
C Copper-fist proteins fungal regulators
C Others
D 112045052 calmodulin-binding transcription activator 2 K21596 CAMTA; calmodulin-binding transcription activator
D 112047422 transcription factor glial cells missing 2-like K21598 GCM; chorion-specific transcription factor GCM
D 112058296 transmembrane protein 18 K22145 TMEM18; transmembrane protein 18
D 112044437 coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial-like K22758 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2
D 112044438 coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial K22758 CHCHD2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2
D 112052246 suppressor of hairless protein K06053 RBPSUH; recombining binding protein suppressor of hairless
D 112052880 uncharacterized protein LOC112052880 K23804 GON4L; GON-4-like protein
D 112055400 uncharacterized protein LOC112055400 K23804 GON4L; GON-4-like protein
D 112047001 transcriptional activator protein Pur-alpha isoform X5 K21772 PURA; transcriptional activator protein Pur-alpha
D 112055794 heterogeneous nuclear ribonucleoprotein M isoform X1 K24992 MYEF2; myelin expression factor 2
D 112050026 uncharacterized protein LOC112050026 K26458 NKRF; NF-kappa-B-repressing factor
#
AProkaryotic type
B Helix-turn-helix
C AraC family
C LysR family
C DeoR family
C LacI family
C GntR family
C TetR/AcrR family
C Lrp/AsnC family
C LuxR family
C MarR family
C MerR family
C Fur family
C IclR family
C CRP/FNR family
C Rrf2 family
C ArsR family
C XRE family
C PadR family
C Other families
B Ribbon-helix-helix
C CopG family
C Other families
B Other transcription factors
C BglG family
C Others
!
#
#[ BRITE | KEGG2 | KEGG ]
#Last updated: June 7, 2024
#
Classification taken and modified from TRANSFAC 7.0