+D Transcription factors KO
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Transcription Factors - Bacillus sp. SD-4
%
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AEukaryotic type
B Basic leucine zipper (bZIP)
C AP-1(-like) components, Jun
C AP-1(-like) components, Fos
C AP-1(-like) components, Maf
C AP-1(-like) components, NF-E2
C AP-1(-like) components, Fungal regulators
C AP-1(-like) components, CRE-BP/ATF
C CREB
C C/EBP-like factors
C bZIP/PAR
C Plant bZIP factors
C ZIP only
B Basic helix-loop-helix (bHLH)
C Ubiquitous (class A) factors
C Myogenic transcription factors
C Achaete-Scute
C Tal/Twist/Atonal/Hen, Lymphoid factors
C Tal/Twist/Atonal/Hen, Mesodermal Twist-like factors
C Tal/Twist/Atonal/Hen, HEN
C Tal/Twist/Atonal/Hen, Mesp
C Tal/Twist/Atonal/Hen, Atonal
C Tal/Twist/Atonal/Hen, Pancreatic factors
C Hairy, Hairy/E(SPL)
C Hairy, Fungal regulators
C Factors with PAS domain
C Yabby
C INO
C HLH domain only
B Basic helix-loop-helix/leucine zipper (bHLH-ZIP)
C Ubiquitous bHLH-ZIP factors
C Cell cycle controlling factors, Myc
C Cell cycle controlling factors, Mad/Max
C Other bHLH-ZIP factors
B Other basic domains
C NF-1
C RF-X
C AP-2 (bHSH)
B Zinc finger
C Cys4 thyroid hormone receptor-like
C Cys4 hepatocyte nuclear factor 4-like
C Cys4 estrogen receptor-like
C Cys4 nerve growth factor IB-like
C Cys4 Fushi tarazu-F1-like
C Cys4 germ cell nuclear factor
C Cys4 Knirps/DAX1-like
C Cys4 GATA-factors
C Cys2His2 SP/KLF family and related proteins
C Cys2His2 GLI-like
C Cys2His2 Snail
C Cys2His2 BTB-ZF factors
C Cys2His2 BED
C Cys2His2 PRDM
C Cys2His2 metabolic regulators in fungi
C Cys2His2 others
C Cys2HisCys zinc factors
C Cys3His zinc factors
C Cys2CysHis zinc factors
C CXXC CpG-binding proteins
D LCG60_16640 dcm; (GenBank) DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D LCG60_22655 dcm; (GenBank) DNA (cytosine-5-)-methyltransferase K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Cys6 metabolic regulators in fungi
C Other zinc fingers
B Helix-turn-helix
C Homeo domain ANTP: HOXL
C Homeo domain ANTP: NKL
C Homeo domain Paired-related
C Homeo domain LIM
C Homeo domain POU
C Homeo domain SINE
C Homeo domain ZF
C Homeo domain CUT
C Homeo domain PROS
C Homeo domain TALE
C Homeo domain other
C Fork head/winged helix developmental regulators
C Fork head/winged helix tissue-specific regulators
C Fork head/winged helix cell cycle-controlling factors, E2F
C Fork head/winged helix cell cycle-controlling factors, DP
C Fork head/winged helix other regulators
C Stork head/winged helix factors
C Heat shock factors
C Tryptophan clusters Myb, Myb-factors
C Tryptophan clusters Myb, Myb-like factors
C Tryptophan clusters Ets-type
C Tryptophan clusters interferon-regulating factors
C TEA domain
C ARID
B beta-Scaffold factors with minor groove contacts
C RHR (Rel homology region) Rel/Ankyrin
C RHR (Rel homology region) Ankyrin only
C RHR (Rel homology region) NF-AT
C STAT
C p53
C MADS-box regulators of differentiation, MEF-2
C MADS-box regulators of differentiation, Homeotic genes
C MADS-box regulators of differentiation, Yeast regulators
C MADS-box responders to external signals
C SAND domain-containing proteins
C TATA-binding proteins
C HMG SOX
C HMG TCF-1
C HMG2-related
C UBF
C Other HMG box factors
C Heteromeric CCAAT factors
C Grainyhead
C Cold-shock domain factors, DbpA-like
C Cold-shock domain factors, YB-1/DbpB-like
C Cold-shock domain factors, FRG Y2-like
C Runt
C MYRF
B Other transcription factors
C HMGI(Y)
C NUPR
C Pocket domain Rb
C Pocket domain CBP
C T-box
C DMRT
C LRRFIP
C TCP
C AP2/ERF
C WRKY
C LOB
C GRAS
C Copper-fist proteins fungal regulators
C Others
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AProkaryotic type
B Helix-turn-helix
C AraC family
D LCG60_07635 AraC family transcriptional regulator K13652 K13652; AraC family transcriptional regulator
D LCG60_05195 AraC family transcriptional regulator K13653 K13653; AraC family transcriptional regulator
D LCG60_15720 AraC family transcriptional regulator K13653 K13653; AraC family transcriptional regulator
D LCG60_06935 bifunctional transcriptional activator/DNA repair enzyme AdaA K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
D LCG60_24420 adaA; (GenBank) bifunctional transcriptional activator/DNA repair enzyme AdaA K13530 adaA; AraC family transcriptional regulator, regulatory protein of adaptative response / methylphosphotriester-DNA alkyltransferase methyltransferase [EC:2.1.1.-]
C LysR family
D LCG60_06715 LysR family transcriptional regulator K21755 bsdA; LysR family transcriptional regulator, salicylic acid-responsive activator of bsdBCD
D LCG60_18800 LysR family transcriptional regulator K21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon
C DeoR family
D LCG60_24520 DeoR/GlpR family DNA-binding transcription regulator K03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor
D LCG60_24615 spoIIID; (GenBank) sporulation transcriptional regulator SpoIIID K06283 spoIIID; putative DeoR family transcriptional regulator, stage III sporulation protein D
D LCG60_02580 helix-turn-helix transcriptional regulator K23774 ccpN; DeoR family transcriptional regulator, catabolite repression regulator
C LacI family
D LCG60_04410 ccpA; (GenBank) catabolite control protein A K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D LCG60_20455 rbsR; (GenBank) ribose operon transcriptional repressor RbsR K02529 galR; LacI family transcriptional regulator, galactose operon repressor
D LCG60_29035 substrate-binding domain-containing protein K02529 galR; LacI family transcriptional regulator, galactose operon repressor
C GntR family
D LCG60_20625 treR; (GenBank) trehalose operon repressor K03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor
D LCG60_01380 phnF; (GenBank) phosphonate metabolism transcriptional regulator PhnF K24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator
D LCG60_24135 GntR family transcriptional regulator K03710 K03710; GntR family transcriptional regulator
D LCG60_14830 FadR family transcriptional regulator K05799 pdhR; GntR family transcriptional regulator, transcriptional repressor for pyruvate dehydrogenase complex
D LCG60_12200 PLP-dependent aminotransferase family protein K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
D LCG60_20860 PLP-dependent aminotransferase family protein K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
D LCG60_25600 PLP-dependent aminotransferase family protein K00375 K00375; GntR family transcriptional regulator / MocR family aminotransferase
D LCG60_09405 PLP-dependent aminotransferase family protein K18907 norG; GntR family transcriptional regulator, regulator for abcA and norABC
D LCG60_01505 GntR family transcriptional regulator K07979 ytrA; GntR family transcriptional regulator
D LCG60_23965 gntR; (GenBank) gluconate operon transcriptional repressor GntR K11476 gntR; GntR family transcriptional regulator, gluconate operon transcriptional repressor
C TetR/AcrR family
D LCG60_03660 TetR family transcriptional regulator K13770 ysiA; TetR/AcrR family transcriptional regulator, fatty acid metabolism regulator protein
D LCG60_08135 TetR family transcriptional regulator K22106 fatR; TetR/AcrR family transcriptional regulator, repressor of fatR-cypB operon
C Lrp/AsnC family
D LCG60_08530 Lrp/AsnC family transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
D LCG60_14535 Lrp/AsnC family transcriptional regulator K03719 lrp; Lrp/AsnC family transcriptional regulator, leucine-responsive regulatory protein
C LuxR family
D LCG60_03540 gerE; (GenBank) spore germination transcription factor GerE K01994 gerE; LuxR family transcriptional regulator, transcriptional regulator of spore coat protein
C MarR family
D LCG60_16010 HTH-type transcriptional regulator Hpr K09682 hpr; MarR family transcriptional regulator, protease production regulatory protein HPr
D LCG60_14665 MarR family transcriptional regulator K15973 mhqR; MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor
D LCG60_03425 MarR family transcriptional regulator K23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator
C MerR family
D LCG60_18945 glnR; (GenBank) transcriptional repressor GlnR K03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor
D LCG60_06200 MerR family transcriptional regulator K11923 cueR; MerR family transcriptional regulator, copper efflux regulator
D LCG60_21640 MerR family transcriptional regulator K22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator
D LCG60_22195 MerR family transcriptional regulator K21902 yfmP; MerR family transcriptional regulator, repressor of the yfmOP operon
C Fur family
D LCG60_01575 transcriptional repressor K03711 fur; Fur family transcriptional regulator, ferric uptake regulator
D LCG60_02505 transcriptional repressor K02076 zurR; Fur family transcriptional regulator, zinc uptake regulator
D LCG60_25405 perR; (GenBank) peroxide-responsive transcriptional repressor PerR K09825 perR; Fur family transcriptional regulator, peroxide stress response regulator
C IclR family
D LCG60_12300 IclR family transcriptional regulator K19333 kdgR; IclR family transcriptional regulator, KDG regulon repressor
C CRP/FNR family
D LCG60_05745 yeiL; (GenBank) transcriptional regulator YeiL K16326 yeiL; CRP/FNR family transcriptional regulator, putaive post-exponential-phase nitrogen-starvation regulator
D LCG60_22380 transcriptional regulator YeiL K16326 yeiL; CRP/FNR family transcriptional regulator, putaive post-exponential-phase nitrogen-starvation regulator
C Rrf2 family
D LCG60_03080 Rrf2 family transcriptional regulator K17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor
C ArsR family
D LCG60_07000 arsR; (GenBank) arsenical resistance operon transcriptional regulator ArsR K03892 arsR; ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
D LCG60_20805 metalloregulator ArsR/SmtB family transcription factor K21903 cadC; ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor
D LCG60_05215 autorepressor SdpR family transcription factor K26993 sdpR; ArsR family transcriptional regulator, repressor of sdpIR and other operons
C XRE family
D LCG60_14930 helix-turn-helix domain-containing protein K19449 sinR; XRE family transcriptional regulator, master regulator for biofilm formation
C PadR family
D LCG60_01265 PadR family transcriptional regulator K10947 K10947; PadR family transcriptional regulator
D LCG60_02140 PadR family transcriptional regulator K10947 K10947; PadR family transcriptional regulator
D LCG60_05810 PadR family transcriptional regulator K10947 K10947; PadR family transcriptional regulator
D LCG60_09885 PadR family transcriptional regulator K10947 K10947; PadR family transcriptional regulator
D LCG60_19205 PadR family transcriptional regulator K10947 K10947; PadR family transcriptional regulator
C Other families
D LCG60_02130 mntR; (GenBank) transcriptional regulator MntR K11924 mntR; DtxR family transcriptional regulator, manganese transport regulator
D LCG60_15845 BlaI/MecI/CopY family transcriptional regulator K02171 blaI; BlaI family transcriptional regulator, penicillinase repressor
D LCG60_21395 biotin--[acetyl-CoA-carboxylase] ligase K03524 birA; BirA family transcriptional regulator, biotin operon repressor / biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]
D LCG60_08525 helix-turn-helix transcriptional regulator K20480 nprR; HTH-type transcriptional regulator, quorum sensing regulator NprR
D LCG60_20790 tetratricopeptide repeat protein K20480 nprR; HTH-type transcriptional regulator, quorum sensing regulator NprR
D LCG60_24970 helix-turn-helix transcriptional regulator K20391 plcR; HTH-type transcriptional regulator, pleiotropic regulator of extracellular virulence genes
D LCG60_13935 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D LCG60_16585 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D LCG60_18190 TrmB family transcriptional regulator K23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator
D LCG60_26810 purR; (GenBank) pur operon repressor K09685 purR; HTH-type transcriptional regulator, purine operon repressor
D LCG60_09015 sigma-54-dependent Fis family transcriptional regulator K21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR
D LCG60_14850 helix-turn-helix domain-containing protein K02647 cdaR; carbohydrate diacid regulator
D LCG60_11200 rocR; (GenBank) arginine utilization transcriptional regulator RocR K06714 rocR; arginine utilization regulatory protein
D LCG60_25180 sigma 54-interacting transcriptional regulator K06714 rocR; arginine utilization regulatory protein
D LCG60_27275 redox-sensing transcriptional repressor Rex K01926 rex; redox-sensing transcriptional repressor
D LCG60_00235 codY; (GenBank) GTP-sensing pleiotropic transcriptional regulator CodY K03706 codY; transcriptional pleiotropic repressor
D LCG60_07895 helix-turn-helix transcriptional regulator K07727 K07727; putative transcriptional regulator
D LCG60_04130 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
D LCG60_06360 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
D LCG60_15030 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
D LCG60_18265 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
D LCG60_18790 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
D LCG60_20305 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
D LCG60_20350 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
D LCG60_23400 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
D LCG60_26215 helix-turn-helix transcriptional regulator K07729 K07729; putative transcriptional regulator
B Ribbon-helix-helix
C CopG family
D LCG60_23515 antitoxin endoai K07723 ndoAI; CopG family transcriptional regulator / antitoxin EndoAI
C Other families
B Other transcription factors
C BglG family
D LCG60_16495 PRD domain-containing protein K03488 licT; beta-glucoside operon transcriptional antiterminator
D LCG60_01370 glcT; (GenBank) ptsGHI operon transcription antiterminator GlcT K03480 glcT; transcriptional antiterminator
D LCG60_08165 BglG family transcription antiterminator K03483 mtlR; mannitol operon transcriptional activator
D LCG60_17195 BglG family transcription antiterminator K03491 licR; probable licABCH operon transcriptional regulator
C Others
D LCG60_24460 metal-sensing transcriptional repressor K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D LCG60_28655 csoR; (GenBank) copper-sensing transcriptional repressor CsoR K21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor
D LCG60_12630 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K06284 abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes
D LCG60_26855 AbrB/MazE/SpoVT family DNA-binding domain-containing protein K06284 abrB; AbrB family transcriptional regulator, transcriptional pleiotropic regulator of transition state genes
D LCG60_26770 spoVT; (GenBank) stage V sporulation protein T K04769 spoVT; AbrB family transcriptional regulator, stage V sporulation protein T
D LCG60_22780 spo0J; (GenBank) stage 0 sporulation protein Spo0J K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D LCG60_22790 noc; (GenBank) nucleoid occlusion protein K03497 parB; ParB family transcriptional regulator, chromosome partitioning protein
D LCG60_04605 transcription factor YdeB K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
D LCG60_19430 transcription factor YdeB K07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription
D LCG60_16100 glpP; (GenBank) glycerol uptake operon antiterminator GlpP K02443 glpP; glycerol uptake operon antiterminator
D LCG60_20945 glycerol-3-phosphate responsive antiterminator K02443 glpP; glycerol uptake operon antiterminator
D LCG60_01980 argR; (GenBank) arginine repressor ArgR K03402 argR; transcriptional regulator of arginine metabolism
D LCG60_02675 hrcA; (GenBank) heat-inducible transcriptional repressor HrcA K03705 hrcA; heat-inducible transcriptional repressor
D LCG60_09700 tenA; (GenBank) thiaminase II K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D LCG60_17480 tenA; (GenBank) thiaminase II K03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]
D LCG60_17460 tenI; (GenBank) thiazole tautomerase TenI K10810 tenI; thiazole tautomerase (transcriptional regulator TenI) [EC:5.3.99.10]
D LCG60_26635 ctsR; (GenBank) transcriptional regulator CtsR K03708 ctsR; transcriptional regulator of stress and heat shock response
D LCG60_18620 cggR; (GenBank) gapA transcriptional regulator CggR K05311 cggR; central glycolytic genes regulator
D LCG60_13170 sugar-binding transcriptional regulator K05346 deoR; deoxyribonucleoside regulator
D LCG60_08020 sugar-binding transcriptional regulator K11531 lsrR; lsr operon transcriptional repressor
D LCG60_00560 pyrR; (GenBank) bifunctional pyrimidine operon transcriptional regulator/uracil phosphoribosyltransferase K02825 pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]
D LCG60_03090 RsfA family transcriptional regulator K06314 rsfA; prespore-specific regulator
D LCG60_22255 RsfA family transcriptional regulator K06314 rsfA; prespore-specific regulator
D LCG60_20090 paiB; (GenBank) protease synthase/sporulation negative transcriptional regulator PaiB K07734 paiB; transcriptional regulator
D LCG60_03915 nrdR; (GenBank) transcriptional regulator NrdR K07738 nrdR; transcriptional repressor NrdR
D LCG60_19405 hutP; (GenBank) hut operon transcriptional regulator HutP K09683 hutP; hut operon positive regulatory protein
D LCG60_15625 competence protein ComK K02250 comK; competence protein ComK
D LCG60_26185 competence protein ComK K02250 comK; competence protein ComK
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: July 3, 2025
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Classification taken and modified from TRANSFAC 7.0